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TRIGGERFISH
Glaucoma Monitoring System
BME 181
Brittany M. Alphonse Biomedical Engineering
Table of Contents



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
Glaucoma
Current Glaucoma
Monitoring Systems
Triggerfish Glaucoma
Monitoring System
Triggerfish System
Components
Benefits
Glaucoma


Progressive and Irreversible Disease

leads to blindness

fluid accumulates in eye
high levels of liquid inside eye
Diameter of cornea changes
Deterioration of Optic Nerve




Asymptomatic
Contributor of disease:

frequent changes in pressure over the span of a day
high peaks in levels during night

40+ years of age


4% of population is affected
Current Glaucoma Monitoring Systems


Measures static intraocular pressure
Single Snapshots in Time


Monitoring in Overnight Sleep Labs



taken during the day when pressure is lowest
cumbersome
expensive
Frequent Punctual Measurements


affects intraocular pressure
checks pressure peaks
Triggerfish System


Created by SENSIMED
First of its Kind on the
market





constant reading device
Safety Approval in
Europe last year
Expected U.S. Food and
Drug Administration
Approval in late 2011


Non-Invasive Continuous
Monitoring System
Measures Intraocular
Pressure up to 24 hours
Does Not Interfere with
Normal Vision
Constant Reading for
Fraction of Price
Triggerfish System Components
Sensor and Processor

Disposable Contact Lens





MEMS Sensor


soft
hydrophilic
silicone
sensor and microprocessor on
outer edge
strain gauge monitors diameter
change in cornea
Telemetry Microprocessor


Processes level changes
transmits to receiver
Components Continued
Antenna

Circular Antenna




taped around the eye
Sends Energy to Sensor
Receives Measurement
Information
Connected to Portable
Recorder

thin flexible data cable
Components Continued
Recorder/ Receiver




Battery Powered
Stores Measured
Information
Wirelessly Uploads
Information
Worn Around Neck
Software


Ophthalmologist
Receives Information
Visualize Intraocular
Pressure Profile
Benefits of Triggerfish System

Improved Understanding of Pressure Change
 pressure



during day versus night
More Efficient
Personalized Drug Delivery and Treatment
Adapt Treatment
 dependent


on changing conditions
Sensor is Placed Outside of Vision Field
Early Diagnosis and Treatment
References for Pictures



http://www.sensimed.ch/S-Trig-benefits.htm
http://www.technologyreview.com/business/24931
/page1/
http://www.sensimed.ch/S-Trig-solution.htm