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Infections / Inflammations Urinary Tract Infection Most common infection complicating Pregnancy Etiology Pressure on ureters and bladder causing Stasis with compression of ureters Reflux Hormonal effects cause decrease tone of bladder Assessment Dysuria, frequency, urgency lower abdominal pain; costal vertebral pain fever Interventions Monthly cultures Oral Sulfonamides; Amoxicillin, Ampicillin, Cephalosporins, NO tetracyclines Increase fluid intake to 3 – 4 liters / day Knee chest position Complication Uterine Irritability, Premature labor T O R C H A Infections T = Toxoplasmosis O = Other Syphilis, Gonorrhea, Chlamydial,Hepatitis A or B R = Rubella C = Cytomegalovirus H = Herpes A = Aids Toxoplasmosis Etiology Protozoan infection. Raw meat and cat litter Maternal and Fetal Effects Mom - flu-like symptoms, lymphadenopathy Fetus – stillborn, premature birth, microcephaly; mental retardation Interventions / Nursing Care Instruct to cook meat thoroughly * Avoid changing cat litter * Advise to wear gloves when working in the garden Treatment: Sulfa drugs * Syphilis Etiology • Spirochete – Treponema Pallium Maternal and Fetal Effects May pass across the placenta to fetus causing spontaneous abortion. Major cause of late,second trimester abortions Infant born with congenital anomalies Syphilis Intervention: • 1. Penicillin • 2. Advise to return for prenatal visits monthly to assess for reinfection. • 3. Advise that if treated early, fetus may not be infected Gonorrhea Etiology – Neisseria Gonorrhoeae Maternal and Fetal Effects: May get infected during vaginal delivery causing Ophthalmia neonatorium (blindness) in the infant Mom will experience dysuria, frequency, urgency Major cause Pelvic Inflammatory Disease which leads to infertility. Treated with Treat partner!! Rocephin Spectinomycin Chlamydia Three times more common than gonorrhea. Etiology – Chlamydia trachomatis Maternal and Fetal Effects Mom – pelvic inflammatory disease, dysuria, abortions, pre-term labor Fetus -- Stillbirth, Chylamydial pneumonia Interventions Erythromycin, doxycycline, zithromax Advise treatment of both partners is very important Hepatitis A or B Highly contagious when transmitted by direct contact with blood or body fluids Maternal and Fetal Effects: • • • All moms should be tested for Hep B during pregnancy Fetus may be born with low birth weight and liver changes\ May be infected through placenta, at time of birth, or breast milk Intervention: • Recommend Hepatitis B vaccination to both mother and baby after delivery. Rubella Etiology Spread by droplet infection or through direct contact with articles contaminated with nasopharyngeal secretions. Crosses placenta Maternal and Fetal Effects Mom– fever, general malaise, rash Most serious problem is to the fetus--causes many congenital anomalies (cataracts, heart defects) Intervention Determine immune status of mother. If titer is low, vaccine given in early postpartum period CYTOMEGALOVIRUS Etiology -- Member of the Herpes virus • Crosses the placenta to the fetus or contracted during delivery. Cannot breast feed because transmitted through breast milk Effects on Mom and Fetus • Mom – no symptoms, not know until after birth of the baby Fetus -- Severe brain damage; Eye damage • Intervention No drug available at this time Teach mom should not breast feed baby Isolate baby after birth Herpes Simplex Type 2 Maternal and Fetal Effects Painful lesions, blisters that may rupture and leave shallow lesions that crust over and disappear in 2-6 weeks Culture lesions to detect if Herpes, No cure If mom has an outbreak close to delivery, then cannot deliver vaginally. Must deliver by Cesarean birth *Virus is lethal to fetus if inoculated at birth Intervention: Zivorax AIDS • Etiology: Human Immunodeficiency Virus, HIV Transmission of HIV to the fetus from seropositive mom by: Perinatal transmission – through the placenta at birth when the infant is exposed to maternal blood and vaginal secretions. Through breast milk **The virus must enter the baby’s bloodstream to produce infection. Maternal and Fetal Effects: Mom - brief febrile illness after exposure to with symptoms of fatigue and lymphadenopathy Fetus has less than 2% chance of being infected because of meds, cesarean delivery, and bottlefeeding. No symptoms until about 1 year of age HIV Diagnosis: The mother can be diagnosed by the ELISA test and confirmed using the Western Blot. Assess immunodeficiency as determined by CD4+ lymphocyte count Evaluate risk of disease progression by assessing plasma HIV-1 which provides information about the viral load (amount of virus present in the body). Interventions Provide Emotional Support Teach measures to promote wellness Give Antiretroviral drugs – zidovudine (ZDV) or Retrovir (AZT) Oral drug daily IV drugs during labor and delivery Oral liquid form of drugs to newborn starting 8 hours after delivery for 6 weeks Provide information about resources The End RETURN