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Hands - on Project idea The process of discovery and development of drugs is ever longer and costly. It happens in an environment of research teams from different organizations (coming from the pharmaceutical industry, academia, SMEs, etc.) often placed in distant locations where there the need for constant discussions and interactions. Those communications seldom take place based on graphical elements (3D, 2D, images…) that might require strict confidentiality due to their high industrial value. Consequently, the majority of interactions is performed in presence meetings, which is costly and time consuming. The idea is to develop a software that enables research teams from the drug discovery and development sector (pharmaceutical, biotechnological, etc) to collaborate from a distance and discuss in real time over graphical elements (3D molecules, result tables, images, etc.) without the need of face-to-face meetings so often, accelerating the entire process. Hands - on Basic Characteristics • Small-medium collaborative project • Funding: around 3.000.000 € • Length: maximum of 3 years • Related fields: IST – eHealth, IST – eWork, GROWTH, Quality of Life, etc. Possible topics: • IST II.2.2: New methods of work and electronic commerce - Smart organisations To explore and validate novel technologies, applications, architectures and practices aimed at supporting the transformation of profit and non-profit entities into "smart" organisations: knowledge driven, internetworked, dynamically adaptive to new organisational forms and practices, learning as well as agile in their ability to create and exploit the opportunities offered by the digital economy.” • IST II.1.5: Promoting broad adoption of eCommerce & eWork in regional and sectoral settings. • GROWTH 1.4.1: New methods of organisation, work and human capital improvement The aim is to develop new organisational and work practices together with developments in industrial products, processes and services, and the appropriate human capital, competence and skills. RTD should address methodologies and tools for efficient organisation, knowledge and technology management, and support close integration and networking of people, organisations and technologies, recognising the importance for innovation / competitiveness of better procurement methods and decision making tools. Hands - on Potential Partners Name Type Country Expertise Profile Fundació Biomèdica (FBM) Non-profit research centre Spain Modelling 3D, software, drug discovery research - Lab. Vida S.A. (LV) Private company Spain Pharmaceutical company Usual collaborator IBMF Technologies (IBMF) Private company UK Software / hardware development generic Known Università de Milano (UMI) Academia Italy Drug discovery research Unknown – Guru Universidade Santiago de Compostela (USC) Academia Spain Drug discovery research Usual collaborator AstraSeneca (AS) Private company Sweden Top pharmaceutical company Unknown Drug Discovery Software Srl (DDS) Private company – SME Italy Molecular software development Known Joint Research Center (JRC) European Commission Europe Generic software research Unknown Digital Security UK (DIGI) Private company UK Security, encryptation Unknown Universitat de Catalunya (UCAT) Academia Spain Software development Known – Guru Instituto de Tecnología de Murcia (ITM) Non-profit research centre Spain Security, encryptation Usual collaborator University of Bremen (UBR) Academia Germany Molecular software development, drug discovery research Unknown – Guru Microsoluciones SL (MICRO) Private company – SME Spain Software development (generic) Usual collaborator Transgen SL (TGEN) Private company France Biotech Unknown University of Düsseldorf (UD) Academia Germany Drug discovery research Usual collaborator Hands - on Exercise 1 1) List the objectives of the project 2) Select an acronym 3) Choose the partners for the consortium Hands - on WRAP-UP 1 Project objectives LINK3D aims to develop, test and prepare the commercial exploitation of a real-time, interactive distant collaboration environment for professionals working in an strategically crucial field: Molecular Discovery (MD). The specific objectives of the project are: 1) To gather detailed requirements of MD professionals in terms of tele collaboration. 2) To develop a set of software applications, configuring a real-time telecollaboration environment for Drug Discovery professionals. 3) To test the system in real-life environments, both for interorganisational and intra-organisational collaborative settings and considering the different types of actors involved (industry, academia). 4) To analyse the potential market, the business possibilities of the LINK3D system, and prepare its commercial exploitation, considering extension to other sectors. Hands - on WRAP-UP 1 Partners LINK3D: Name Type Country Expertise Profile Fundació Biomèdica (FBM) Non-profit research centre Spain Modelling 3D, software, drug discovery research - Lab. Vida S.A. (LV) Private company Spain Pharmaceutical company Usual collaborator AstraSeneca (AS) Private company Sweden Pharmaceutical company Unknown Drug Discovery Software Srl (DDS) Private company – SME Italy Molecular software development Known Digital Security UK (DIGI) Private company UK Security, encryptation Unknown Universitat de Catalunya (UCAT) Academia Spain Software development Known – Guru University of Düsseldorf (UD) Academia Germany Drug discovery research Usual collaborator Hands - on Exercise 2 1) List the Work Packages 2) Define Deliverables and Milestones 3) Assign Work Packages Leaders Hands - on WRAP-UP 2 List of Work Packages: WP1 Project management and co-ordination (FBM) WP2 User requirements gathering (FBM) WP3 System specifications (DDS) WP4 System development (UCAT) WP5 In-process testing (DDS) WP6 Real-world testing (FBM) WP7 Exploitation (DDS) WP8 Dissemination (FBM) WP9 Assessment and evaluation (FBM) Hands - on WRAP-UP 2 Tasks: WP1 Project management and co-ordination (FBM) T1.1. Day to day operational management T1.2. Project co-ordination WP2 User requirements gathering (FBM) T2.1 Planning T2.2 Execution T2.3 Analysis of results WP3 System specifications (DDS) T3.1 File formats T3.2 Communication protocols T3.3 Security issues T3.4 Definition of standard hardware configuration requirements T3.5 Global definition of the system specifications Hands - on WRAP-UP 2 Lista de Tasks: WP4 System development (UCAT) T4.1 Development of the communication protocols T4.2 Development of the whiteboard metaphors and graphical engines T4.3 Development of the security T4.4 System adjustments T4.5 User manuals WP5 In-process testing (DDS) T5.1 Planning T5.2 Execution T5.3 Analysis of results Hands - on WRAP-UP 2 Tasks: WP6 Real-world testing (FBM) T6.1 Testing planning (inter-organisational setting) T6.2 Testing execution (inter-organisational setting) T6.3 Analysis of results (inter-organisational setting) T6.4 Testing planning (intra-organisational setting) T6.5 Testing execution (intra-organisational setting) T6.6 Analysis of results (intra-organisational setting) T6.7 Integration of testing results WP7 Exploitation (DDS) T7.1 Market analysis T7.2 IPR issues T7.3 Business plan T7.4 Extension to other industrial sectors Hands - on WRAP-UP 2 Tasks: WP8 Dissemination (FBM) T8.1 Web site T8.2 Brochure T8.3 Other activities WP9 Assessment and evaluation (FBM) T9.1. Quality assurance T9.2. Risk management T9.3. Project evaluation Hands - on WRAP-UP 2 Deliverables list: Del. no. Deliverable name WP no. Del. type* Delivery (proj. month) D1 Report on the set-up of the organisation and infrastructure of the LINK3D project 1 Report 3 D2 Project presentation 8 Document 3 D3 Report on user requirements (investigation methods and results) 2 Report 4 D4 Dissemination and use plan 8 Report 6 D5 Report on the specifications of the LINK3D system 3 Specification 7 D6 First version of the LINK3D system including user manuals 4 Prototype 19 D7 Report on the in-process testing (methods and results) 5 Report 19 D8 First report on real-world testing of the LINK3D system (methods and results) 6 Report 22 D9 Report on the specifications of the improved LINK3D system 3 Specification 23 D10 Report on market analysis 7 Report 24 D11 Improved version of the LINK3D system including user manuals 4 Prototype 26 D12 Final report on real-world testing of the LINK3D system (methods and results) 6 Report 29 D13 Final report on dissemination activities 8 Report 30 D14 Report on the business plan 7 Report 30 D15 Assessment and evaluation report 9 Report 30 Hands - on WRAP-UP 2 Milestones list: M1 Definition of user requirements M2 Completion of the system specifications (first version) M3 Completion of the first version of the LINK3D system M4 Completion of the first stage of the real-world testing M5 Completion of the market analysis M6 Completion of the improved system specifications M7 Completion of an improved version of the LINK3D system M8 Completion of the second stage of the real-world testing M9 Completion of the business plan M10 LINK3D project completion Hands - on Exercise 3 1) GANTT chart 2) PERT diagram Hands - on WRAP-UP 3 Hands - on Exercise 4 • Responsibility Assignment Matrix, defined by project roles R: Responsible W: Major contribution I: Minor contribution Hands - on WRAP-UP 4: RAM LINK3D FMB LV AS WP1 - Project Management and Coordination R WP2 - User requirements gathering R WP3 - System specifications I WP4 - System development W WP5 - In-process testing R I I WP6 - Real-world testing R W W WP7 - Exploitation W WP8 - Dissemination R WP9 - Assessment and evaluation R DDS DIGI W W UD W W W R I UCAT W W W W R W W I W R W I I I I I I I I I I Hands - on Exercise 5 • RAM of efforts • 3 steps: • Relative weight of each WP • Estimate the total effort amount • Estimate the breakdown of efforts per task Hint: the total amount can be estimated dividing the total funding by 5000-10000 Euro (depending on the consortium profile). Hint: Estimate the relation between R, W, I: • W= 2 I • R= 3 I Hands - on WRAP-UP 5: RAM LINK3D FMB LV AS WP1 - Project Management and Coordination 15 WP2 - User requirements gathering 17 WP3 - System specifications 4 WP4 - System development 36 WP5 - In-process testing 13 4 4 WP6 - Real-world testing 35 23 23 WP7 - Exploitation 13 WP8 - Dissemination 8 WP9 - Assessment and evaluation 11 DDS DIGI 10 11 UD 10 11 11 13 3 UCAT 8 pm total pm target Weight WP 35 35 7 50 50 10 9 9 35 35 7 36 54 125 125 25 8 8 4 50 50 10 23 105 105 21 50 50 10 25 25 5 25 25 5 500 100 19 13 6 3 3 3 3 4 4 4 4 3 total pm 151 41 45 57 72 93 41 500 Full-time Equivalents (FTE) 4,2 1,1 1,2 1,6 2,0 2,6 1,1 13,9 Hands - on Exercise 6 • Construct the budget • Take into account the type of expenditure: personnel, equipment, consumables, travel, subcontracting, indirect costs. • Take into account that funding agencies do not always cover 100% of the direct costs of the project (difference between “budget” and “funding”). Hands - on WRAP-UP 6: Budget LINK3D FMB LV AS DDS DIGI UCAT UD total pm 151 41 45 57 72 93 41 Full-time Equivalents (FTE) 4,2 1,1 1,2 1,6 2,0 2,6 1,1 4000 4500 6000 5500 7000 3500 3900 0,6 0,45 0,3 0,6 0,6 0,6 0,6 45000 30000 30000 45000 30000 45000 30000 104 39 39 21 53 71 39 417024 173750 231667 118021 369583 247292 150583 Other direct costs 31110 27987 25763 17073 22107 34095 27987 Overheads max. 268880 78188 77229 81056 235014 168832 107142 Total costs 717014 279924 334659 216151 626705 450218 285712 EC contribution 537761 139962 167330 162113 313353 337664 214284 15 0 0 10 0 10 0 Personnel costs 60000 0 0 55000 0 35000 0 Subcontracting 2000 0 0 1000 1000 1000 0 Other direct costs 4476 0 0 7956 0 4826 0 Overheads max. 38686 0 0 37774 0 23895 0 Total costs 105162 0 0 101730 1000 64721 0 EC contribution 105162 0 0 101730 1000 64721 0 Average personnel rate Overhead rate Other costs (travel, consumables, etc.) RTD total pm Personnel costs Subcontracting Management total pm Hands - on WRAP-UP 6: Budget LINK3D Other FMB LV AS DDS DIGI UCAT UD 32 3 6 25 19 13 3 126190 12500 38095 138046 131944 44097 10833 Other direct costs 9414 2013 4237 19970 7893 6080 2013 Overheads max. 81363 5625 12700 94809 83902 30106 7708 Total costs 216967 20138 55031 252825 223739 80283 20555 EC contribution 216967 20138 55031 252825 223739 80283 20555 151 41 45 57 72 93 41 500,0 Personnel costs 603214 186250 269762 311066 501528 326389 161417 2359626 Subcontracting 2000 0 0 1000 1000 1000 0 5000 Other direct costs 45000 30000 30000 45000 30000 45000 30000 255000 Overheads max. 388929 83813 89929 213640 318917 222833 114850 1432910 Total costs 1039143 300063 389690 570706 851444 595222 306267 4052536 TOTAL COSTS EC contribution 859889 160100 222361 516669 538092 482668 234839 3014618 TOTAL FUNDING total pm Personnel costs Subcontracting TOTAL total pm