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TM PureHeart Barry W. Ritz, PhD Institute for Functional Medicine May 30, 2013 Screening + Supplements = SuccessTM “Beyond Lipids” • Underlying factors • Lipid balance • Blood flow, vascular function • CoQ10 status • Glucose metabolism • Oxidative stress • Co-support • Medications • Supplements • Lifestyle www.pureheartprotocol.com Cleveland HeartLab Roadmap Step 1 Step 2 Step 3 Contact Cleveland HeartLab® Determine Clinical Goals -algorithms Choose from Pure Encapsulations® Supplements www.pureheartprotocol.com Retest after 3-6 months Cleveland HeartLab Roadmap Step 1 Step 2 Contact Cleveland HeartLab® Determine Clinical Goals Myeloperoxidase (MPO): Proprietary marker for arterial wall health. ≥ 480 pmol/L Step 3 Choose from Pure Encapsulations® Supplements Support healthy Alpha Lipoic Acid glucose metabolism* w/GlucophenolTM, Metabolic Xtra Support healthy SR-CoQ10 w/PQQ or CoQ10 levels* Ubiquinol VESIsorb® Support antioxidant defense* ResCu-SRTM or Resveratrol VESIsorb® *These statements have not been reviewed by the Food & Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease. Pure Encapsulations® Supplements • • • • • Research-based Professionally dosed Hypoallergenic Formulated for sensitive individuals Avoiding: Common allergens, coatings, shellacs, binders, fillers, excipients, artificial flavors, artificial sweeteners, or colors *These statements have not been evaluated by the Food & Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease. Healthy glucose metabolism* Metabolic Xtra • Berberine HCl, alpha-lipoic acid, resVida (transresveratrol), Zychome (Cr dinicocysteinate) • Insulin receptor function (AMPK, SIRT1) and glucose homeostasis* *These statements have not been evaluated by the Food & Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease. Healthy glucose metabolism* Alpha Lipoic Acid w/ Glucophenol Insulin sensitivity and glucose clearance* *These statements have not been evaluated by the Food & Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease. * Inflammation Response Glucose Uptake Healthy glucose metabolism* * *These statements have not been evaluated by the Food & Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease. Plasma CoQ10 (mcg/mL) Healthy CoQ10 levels* SR-CoQ10 with PQQ Extended Release • Microactive® slow release CoQ10 • PQQ (pyrroloquinoline quinone) • Complementary mechanisms in cardioprotection and cognitive/neuronal health* *These statements have not been evaluated by the Food & Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease. Healthy CoQ10 levels* Ubiquinol VESIsorb • Ubiquinol- Active antioxidant form of CoQ10 • Self-assembling colloidal delivery system for maximum absorption *These statements have not been evaluated by the Food & Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease. Healthy CoQ10 levels* *These statements have not been evaluated by the Food & Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease. Resveratrol Antioxidant defense* • Microactive® high bioavailability, sustained release resveratrol and curcumin- consistent delivery • Exclusive, proprietary formula Curcumin ResCu-SRTM *These statements have not been evaluated by the Food & Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease. ResCu-SRTM Antioxidant defense* Payette C et al. Sex differences in postprandial plasma tumor necrosis factor-α, interleukin-6, and C-reactive protein concentrations. Metab Clin Exp (2009) 58:1593-1601 *These statements have not been evaluated by the Food & Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease. Screening + Supplements = SuccessTM • • Easy as 1-2-3 Please visit our microsite for more information • ResCu-SR www.PureHeartProtocol.com