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Estimating cost of dengue
treatment: Khon-Kaen Hospital,
THAILAND
Sukhontha Kongsin1, Sukhum Jiamton2,
Sirijitt Vasanawathana3, Petcherut Sirisuwan1,
Jose A. Suaya4 , Donald S. Shepard4
1Faculty
2Faculty
of Public Health, Mahidol University, Bangkok, Thailand
of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand
3Khon-Kaen Hospital, Thailand; 3Brandeis University, USA
ASTMH Annual Meeting
New Orleans, LA
Dec. 11, 2008
OBJECTIVE
To estimate the cost of dengue
hospitalised episode in one selected
province: Khon-Kaen Provincial
Hospital
Framework: Estimating cost of
dengue hospitalised episode
Cost of dengue
hospitalised
episode
DATA COLLECTION
 Subjects (or caregivers) interviewed once or twice
about illness, treatment, and caregiver visits.
 Medical record extraction form
 Lab data collected from records or tests during the
study.
 Information entered into customised Microsoft
Access database.
 Data exported to Excel and SPSS, cleaned,
aggregated by subject.
DATA ANALYSIS
 Key formula.
Total cost of resources- Quantity x unit cost.
 Quantity and unit cost can be obtained from
separate data sources.
 Example 1: Hospital costs
Hospitalisation cost- length of stay x cost per day
 Example 2: Lost time from self-employment or
household activities
Cost of lost time- day lost x value per day
CHARACTERISTICS OF THAILAND
Currency name
Exchange rate used
Baht
39.00
GDP, US$/capita
GDP, I$/capita
Ratio: GDP I$ / US$
2,750
8,440
3.07
Minimum daily wage, I$ (US$)
Cost per day of school, I$ (US$)
11.0 (3.6)
5.8 (1.9)
CHARACTERISTICS OF KHON-KAEN
PROVINCE (STUDY SITE)
Population (millions)
1.70
Main year of recruitment for study
Reported dengue cases in location
Children (0-14 yrs.), %
2005
746
78%
Adults (15 plus yrs.), %
Circulating dengue serotypes
Predominant
Unit costs in participating facilities
Per inpatient bed day, I$ (US$)
Per ambulatory visit, I$ (US$)
22%
1,2,3,4
4
263.9(86.0)
39.6(12.9)
CHARACTERISTICS OF PARTICIPANTS
Number of participants
Urban residence, %
Maximum level of education in household
Primary school or less, %
Secondary school, %
Vocational, college, or more, %
Dengue confirmed*, %
Days of fever, mean ± SD
Days of illness, mean ± SD
Any bleeding, %
Any leakage, %
173
30%
49%
31%
20%
24%
6.0 ± 3.5
10.8 ± 5.0
89%
66%
UTILIZATION OF HEALTH SERVICES AND IMPACT
PER DENGUE CASE BY STUDY SITE
Number of participants
Studying, %
Working, %
Health services utilization
Ambulatory visits, mean ± SD
Share in private sector, %
Hospital days, mean ± SD
Share in private sector, %
Household impact
School days lost, mean ± SD
Borne by patient, %
Work days lost, mean ± SD
Borne by patient, %
Total days affected, mean ± SD*
Borne by patient, %
173
100%
0%
4.2 ± 2.0
13%
4.9 ± 3.3
0%
5.5 ± 3.4
100%
3.9 ± 5.0
0%
18.6 ± 10.4
59%
MEANS (± STANDARD DEVIATIONS) OF COST
COMPONENTS PER DENGUE CASE
Direct cost, I$
Medical cost
Non-medical cost
Sub-total
1,436 ± 902
186 ± 129
1,621 ± 998
Indirect cost, I$
137 ± 99
Grand total cost, hospitalized case
In I$,
In US$
In days of GDP/capita
1,758 ± 1,079
573 ± 351
76 ± 47
82%
11%
92%
8%
100%
CONCLUSIONS
 The economic cost of dengue per case is
substantial
 The main component of the cost is the
hospital care, paid largely by government
 As the patients were children, the indirect
costs were relatively small
 Other studies that focused only on out of
pocket costs to households gave substantially
smaller numbers
Acknowledgements
 All dengue patients in the study
 All staff members: Khon-Kaen Hospital
 Mentors: Scott Halstead
 Special thanks to PDVI for financial support
 We highly appreciate supports from
Drs. Somsak Chunharas, Sutee Yoksan, Suwich
Thammapalo, Prida Malasit, Kanittha Boonthamchareon,
Nattakamol Chansathitporn and
Viroj Tangchareonsathein.