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Mad Cow Disease Scrapie in sheep SKEPTICS????? What are proteins? How do they differ from DNA and RNA? How can a protein without hereditary material infect another organism and the increase in numbers resulting in disease??????? BIOCHEMISTRY!!! The chemistry of life………….. 2 General Categories of Compounds… 1. They DO NOT contain carbon! 2. Inorganic Compounds: Organic Compounds: The DO contain carbon! Carbon Compounds!!! The “Swiss Army Knife” of Chemistry!!! Chapter 3 4 major organic compounds we will be learning about are: 1. carbohydrates 2. lipids 3. proteins 4. nucleic acids Review: Atoms Atomic mass = P and N (nucleus) Atomic no. = # of P (same as no. of e-) Shells: “maximum” 1st shell = 2 electrons 2nd shell = 8 electrons 3rd shell = 8 electrons 4th shell = 18 electrons 5th shell = 18 electrons 6th shell = 32 electrons 7th shell = 32 electrons What does each line (bond) represent?? Each line represents a pair of electrons from the OUTER RINGS OF THE ATOMS. Let’s try CH4 Carbon’s atomic number is 6 Hydrogen’s atomic number is 1 DRAW THIS COMPOUND WITH COVALENT BONDS, THEN A STRUCTURAL FORMULA! Carbon Bonding! * Carbon is essential to life for several reasons: It can form strong stable (usually non-polar) covalent bonds It can form up to 4 chemical bonds It can form multiple bonds Carbon can bond to form a number of different shapes! Straight chain, branched and ring!! Large Carbon Molecules 1. Monomers = small simple molecule. 2. Polymers = repeated single molecule units linked together Continue… 3. Macromolecules: large polymers Functional Groups Clusters of atoms that influence the properties of the molecules they compose! 1. Hydroxyl group -OH Alcohol (usually “ol” ending) Organic compound with hydroxyl group attached to one of its carbon atoms Examples: 1. ethanol = found in alcoholic beverages, causes cell death in liver and brain cells CH3CH2OH More Examples of Alcohols 2. Methanol = wood alcohol, can cause blindness or even death when consumed (formaldehyde) 3. Glycerol = humans need this alcohol to assemble certain molecules necessary for life (lipids) 4 Major Elements in Living Organisms!! – show examples! Carbon: 4 bonds - “C” Nitrogen: 3 Bonds - “N” Oxygen: 2 bonds - “O” Hydrogen: 1 bond - “H” Let’s Practice!! Molecular Formulas = WORDS IN CHEMISTRY!! Structural Formulas = PICTURES IN CHEMISTRY!!! Draw the structural formulas for the following: H2O CO2 CH3OH CH3CH2CH2CH2CH3 CH3CH2OH CH3CHOHCHOHCH2OH Still Harder!!! H2NCH2COOH C6H12O6 What is the molecular formula for the following? What is the molecular formula?? Let us practice with “Play-doh”……. Cell’s energy: ATP + H2OADP The energy compound of living cells! Adenosine triphosphate ATP * Short for Adenosine Tri-Phosphate. ATP is closely related to nucleic acids. Composed of Ribose, Adenine & a phosphate group Phosphate group has ability to bind/release additional phosphate group allowing it to store or release energy