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Cell Division
Mitosis & Cytokinesis
Cell Division = Mitosis
“ During
life, we
go from one cell
to ~ 75 trillion
cells.
“ Mitosis=
process of
division of a
somatic cell
(not a sex cell)
Cell Division - 2 Parts
I. Mitosis =
cell (nuclear) division
II. Cytokinesis =
division of cytoplasm,
formation of
2 identical cells
Sequence of Cell Cycle
IPMAT
“Interphase
“Prophase
“Metaphase
“Anaphase
“Telophase
Mitosis Includes :
“Prophase
“Metaphase
“Anaphase
“Telophase
Cytokinesis
(division of cytoplasm)
Cytokinesis
(division of cytoplasm)
“ Starts
during Mitosis (Telophase)
“ Completed
after Mitosis is
complete
During Interphase :
“Normal
cell f(x)s
“DNA Synthesis
“Duplication of
organelles
“DNA in form of
chromatin
Prophase
“ Chromosomes
coil & bcm
visible Sister
chromatids
“ Nuclear
envelope
disappears
“ Nucleolus
disappears
“ Spindle forms
Sister chromatid
Prophase
“Spindle
forms
between
centrioles
“Nuclear
envelope and
nucleoli
disappear
Prophase
Prepare to divide!
Metaphase
“ Sister
chromatids line
up at equator
of the
metaphase
plate
spindle
pole
Sister
chromatid
Metaphase
Meet me in the middle,
metaphase!
Anaphase
“ Centromeres
divide
“ Sister chromatids
separate from one
another
“ Sister chromatids
move to opposite
poles (centrioles)
Anaphase
Run away, run away!
Telophase
“ Chromosomes
uncoil and become
invisible (now in form of chromatin)
“ Spindle disappears
“ Nuclear envelope
“ Nucleolus re-appears
(Cell prepares to return to interphase
state)
Cytokinesis
“ Division
into two identical DAUGHTER
CELLS
“ Starts during Telophase
“ Finishes after Telophase is over
Animation of mitosis &
cytokinesis
animation
Whitefish cells during mitosis
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