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Structure and Function of the Plasma Membrane • Each living cell exists in a watery environment, which allows dissolved materials to move in and out the cell like oxygen, food & nutrients. • As the cell reacts with it’s ever changing surroundings it actively tries to keep conditions inside itself pretty constant. This internal balancing of conditions is called homeostasis. The Cell Membrane Function: All cells use the cell membrane to help maintain homeostasis. This is due to the membrane being selectively permeable meaning it can pick and choose what comes into and out of the cell. Structure: The membrane’s function is directly related to its structure. It consists of a lipid bilayer made of two layers of phospholipids sandwiched together and dotted with different types of proteins. Notice the polar heads (water loving) and non-polar tails (water fearing) Passive Transport vs. Active Weeee!! Transport ! • Passive transport – – Cell doesn’t use energy – Random movement of molecules from a high to low concentration. high low • Active transport – – Cell uses energy – Directed movement of molecules from a low to high concentration. This is gonna be hard work!! high low Passive Transport 3 types of passive transport: • Diffusion - transport of substances • Osmosis – transport of water • Facilitative Diffusion – transport with the help of carrier proteins (for molecules too large to pass through the membrane without help) Diffusion Transport of substances (other than water) from areas of high to low concentration. Diffusion occurs until the molecules are distributed evenly throughout. Diffusion Through Cell Uncharged and veryMembranes small molecules CO move straight through the middle non-polar region of the cell membrane without breaking it until equilibrium is reached (the same amount of solutes on both sides). These include very small molecules like oxygen, carbon dioxide, and water. For example: The capillary below is returning blood to the lungs, thus has a high concentration of carbon dioxide. The air sacs in the lungs have a lower concentration of carbon dioxide. Which way will the carbon dioxide go? CO2 2 CO2 CO2 CO2 CO2 CO2 CO2 bloodstream air sacs Osmosis • The diffusion of water across a selectively permeable membrane (high to low concentration) Notice the water rises on the left side of the tube, as water moves from right to left. The sugar concentration is higher on the left, so water moves through the membrane until the solutions are about equal in terms of sugar concentration Facilitated Diffusion • Diffusion of molecules with the aid of carrier proteins, located in the cell membrane, from high to low concentration Larger and charged ions or molecules are repelled by the cell membrane and must be transported through “doors” in the membrane called transport proteins. There are many different “doors” each only allowing a specific type of molecule through. Passive Transport vs. Active Weeee!! Transport ! • Passive transport – – Cell doesn’t use energy – Random movement of molecules from a high to low concentration. high low • Active transport – – Cell uses energy – Directed movement of molecules from a low to high concentration. – 3 Types • Protein Pumps • Endocytosis • Exocytosis This is gonna be hard work!! high low Protein Pump Sodium Potassium Pumps (Active Transport using proteins) 1. Protein Pumps transport proteins that require energy to do work •Example: Sodium / Potassium Pumps are important in nerve Protein changes shape to move responses. molecules: this requires energy! Types of Endocytosis Endocytosis – takes materials into the cell (low to high concentration) Examples Endocytosis Macrophage (white blood cell) engulfing bacteria Amoeba engulfing food. Exocytosis: materials exit the cell (low to high concentration)