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Informatics Research Directions
SysMO/EraSysBIO
• Workflows running behind a web page
– Better support for viewing data
inputs/outputs/tweaking parameters
• Research Objects (with and without workflow
components)
• Read/write from spreadsheets and in Sys Bio
formats
Systems Biology
• Workflows for finding and extracting
parameter values and/or experimental data
for plotting against model simulations
• Pathway analyses
• Omics analyses – microarray, proteomics etc
• Comparative genomics
Main Areas
• Next Gen sequencing
– Downstream analysis
– Genomic data mining
• Medical Systems Biology
– Very familiar comparative genomics, multi-omics
analysis and eventually linking data and models
– Big distributed consortia, impact
• BioBanking
Other local users
• Ancient DNA Next Gen data. Ancient TB
infection
• Sort of local – Afsaneh pulmonary diseases
systems biology
• Work with gynacolgy department – rerunn of
Paul and Afsaneh’s microarray workflows
Features from other projects that
would be useful
• Sparql service from eLico
• Shim library from Next Gen workbench
• Better support for adding local/remote perl
scripts – external tools?/scape
• More support for running workflows over web
• Renderers –
– cytoscape (elico),
– DAS/genome browser (TSB?)
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