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Prevention Strategies:
Emerging Trends and Issues
Kimberly E. Davis, Ph.D.
July 17, 2010
Center for Cancer Research and Therapeutic Development
Center for Cancer Research and Therapeutic Development
• New cases in 2009: 192,280
• Deaths in 2009: 27,360
• Approximately 1 in 6 American men
Source: American Cancer Society. Cancer Facts & Figures 2009. Atlanta: American Cancer Society; 2009.
Center for Cancer Research and Therapeutic Development
• Prostate cancer is detected at an earlier age in
African-American men than Caucasian men and
they had a higher PSA level at diagnosis.
• Prostate Cancer incidence and mortality is higher
in African-American men than any other ethnic
group.
Sources: Horner MJ, Ries LAG, Krapcho M, Neyman N, Aminou R, Howlader N, Altekruse SF, Feuer EJ, Huang L, Mariotto A, Miller
BA, Lewis DR, Eisner MP, Stinchcomb DG
Edwards BK (eds). SEER Cancer Statistics Review, 1975-2006, National Cancer Institute. Bethesda, MD,
http://seer.cancer.gov/csr/1975_2006/, based on November 2008 SEER data submission, posted to the SEER web site, 2009.
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Incidence
Mortality
Source: SEER 9 areas. Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103).
Regression lines are calculated using the Joinpoint Regression Program Version 3.3.1, April 2008, National Cancer
Institute.
Center for Cancer Research and Therapeutic Development
• Health Lifestyle Factors
–Eat Sensibly
–Stop smoking if you smoke
–Drink alcohol in moderation
–Be physically active
–Maintain a healthy weight.
–Limit your chemical exposure (pesticides
and herbicides)
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• Guidelines for a Healthy Diet
–5+ servings of fruits and vegetables per
day
–Limit red meat (beef, pork, or lamb) and
processed meats (hot dogs or luncheon
meats)
–Plant Based Diet
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• Limit High Fat Foods
– fast food, fried food, baked goods
• Limit Simple Carbohydrates
– table sugar, fruit juice, soda, corn syrup
• High Fiber Diet
– apples, citrus fruits, oat bran
• Omega 3 Fatty Acid
– salmon, mackerel, nuts,
• Omega 9 Fatty Acid
– olive oil and canola oil
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•
•
•
•
•
Lycopene
Pomegranates
Selenium and Vitamin E
Calcium
Vitamin D
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• Race / Ethnicity
– African-American men have the highest risk and are
more likely to be diagnosed at an advanced stage.
• Family History
– Having a father or brother with prostate cancer more
than doubles a man’s risk of developing this disease
– This risk is much higher for men with several affected
relatives, particularly if their relatives were young at the
time the cancer is found.
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• African-American men should be screened
for prostate cancer after of age of 45.
• Prostate cancer is 95% treatable if detected
early.
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• Basic Research
• Genetics
• Prevention
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QUESTIONS
Kimberly E. Davis, Ph.D.
[email protected]
Center for Cancer Research and Therapeutic Development