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Pre eventiion an nd Ma anage ementt of O Obesitty – Ad dult – Amb bulato ory Clinica C al Pra actice e Guid deline e 1 Note: Active Table of Contents – Click to follow link TableofContents EXECUTIVE SUMMARY .............................................................................................................. 3 SCOPE ......................................................................................................................................... 3 METHODOLOGY ......................................................................................................................... 4 INTRODUCTION .......................................................................................................................... 5 RECOMMENDATIONS ................................................................................................................ 5 REFERENCES ............................................................................................................................. 6 Release Date: May 2015 Next Review Date: May 2017 2 ExecutiveSummary Guideline Overview The workgroup has agreed to endorse the 2013 Prevention and Management of Obesity for Adults created by the Institute for Clinical Systems Improvement (ICSI).1 Key Practice Recommendations 1. Clinicians should calculate body mass index (BMI) for their patients on an annual basis for screening and as needed for management. Classify BMI based on the body mass categories. Educate patients about their body mass index and associated risks for them. (ICSI Strong Recommendation, High Quality Evidence) 2. Clinicians should consider waist circumference measurement to estimate disease risk for patients who have normal or overweight BMI scores. (ICSI Strong Recommendation, Moderate Quality Evidence) 3. Clinicians need to carefully consider BMI and its associated mortality risk across different ethnicity, sex and age groups. (ICSI Strong Recommendation/Moderate Quality Evidence) 4. Waist circumference greater than or equal to 40 inches for males and 35 inches for females is an additional risk factor for complications related to obesity. Measuring waist circumference is recommended to further assess the patient. (ICSI Weak Recommendation, Moderate Quality Evidence) 5. Clinicians should use motivational interviewing techniques as a tool for encouraging behavior change. (ICSI Strong Recommendation, Moderate Quality Evidence) Companion/Collateral Documents 1. Prevention and Diagnosis Algorithm 2. BMI Index Ranges 3. FDA Approved Treatment of Obesity in Adults External Resources 1. Unity Health Insurance - Weight Management 2. Group Health Cooperative - Weight Management 3. Physicians Plus - Weight Management 4. Dean - Weight Management Scope Disease/Condition(s): Obesity, Overweight Clinical Specialty: Endocrinology, Family Medicine, Internal Medicine, Nursing, Nutrition, Preventive Medicine, and Surgery 3 Intended Users: Primary Care Physicians, Specialty Care Physicians, Advanced Practice Providers, Registered Dietitians, Pharmacists, Nursing Objective(s): To establish evidence-based recommendations for obesity prevention, diagnosis, and weight management in adult patients. Target Population: All adults 18 years of age and older. This guideline does not address pregnant women or bodybuilders/weight trainers. Interventions and Practices Considered: Behavioral approaches o o o o o Drug treatment o o o o Motivational Interviewing Goal setting Nutrition recommendations Physical activity prescription Behavioral management strategies Phentermine Orlistat Qsymia Lorcaserin Surgery. o o o o Adjustable Band Sleeve Gastrectomy Gastric Bypass Duodenal Switch Methodology Methods Used to Collect/Select the Evidence: Identification and selection of the evidence was completed by the Institute for Clinical Systems Improvement (ICSI). Literature search terms for the current revision of this document included adults (18 years and older), published since January 2005 – systematic reviews, randomized control trials, meta-analysis restricted to human studies, in the following topic areas: prevention, screening, treatments/drug studies, medications, gastric bypass and/or bariatric surgery, lipid and cholesterol screening, activity recommendations, genetic studies, activity recommendations, family-based therapy, readiness for change, motivational interviewing, goal setting, managing chronic conditions, binge eating disorders, binge eating disorder assessment and scale, and obesity with diabetes. Rating Scheme for the Strength of the Evidence/Recommendations: The quality of the evidence was rated using the Grading of Recommendations Assessment, Development and Evaluation (GRADE). See table below. 4 Table 1. ICSI GRADE Scheme Category High Quality Evidence Quality Definitions Further research is very unlikely to change our confidence in the estimate of effect. Moderate Quality Evidence Further research is likely to have an important impact on our confidence in the estimate of effect and may change the estimate. Low Quality Evidence Further research is very likely to have an important impact on our confidence in the estimate of effect and is likely to change. The estimate or any estimate of effect is very uncertain. Strong Recommendation The work group is confident that the desirable effects of adhering to this recommendation outweigh the undesirable effects. This is a strong recommendation for or against. This applies to most patients. The work group is confident that the benefits outweigh the risks but recognizes that the evidence has limitations. Further evidence may impact this recommendation. This is likely a recommendation that applies to all patients. The work group feels that the evidence consistently indicates the benefit of this action outweighs the harms. This recommendation might change when higher quality evidence becomes available. Weak Recommendation The work group recognizes that the evidence, though of high quality, shows a balance between estimates of harms and benefits. The best action will depend on local circumstances, patient values of preferences. The work group recognizes that there is a balance between harms and benefits, based on moderate quality evidence, or that there is uncertainty about the estimates of the harms and benefits of the proposed intervention that may be affected by new evidence. Alternative approaches will likely be better for some patients under some circumstances. The work group recognizes that there is significant uncertainty about the best estimates of benefits and harms. Introduction Over one third of adults in the United States are obese.4 Obesity is the second leading cause of preventable death, and associated with medical costs as much as $147 billion to $210 billion a year.5 Comorbidities include Type 2 diabetes, heart disease, hypertension, dyslipidemia, and certain cancers. Depression and obesity frequently cooccur.6 A 5-10% weight loss can reduce a patient’s risk of heart disease and diabetes that is clinically significant. This can be achieved and maintained with a high-intensity medical weight loss program even for the morbidly obese.1 Recommendations Recommendations related to the prevention, diagnosis and management of obesity in adult patients can be found in the 2013 ICSI guideline below or online at https://www.icsi.org/guidelines__more/catalog_guidelines_and_more/catalog_guidelines /catalog_endocrine_guidelines/obesity__adults/. Disclaimer CPGs are described to assist clinicians by providing a framework for the evaluation and treatment of patients. This Clinical Practice Guideline outlines the preferred approach for most patients. It is not intended to replace a clinician’s judgment or to establish a protocol for all patients. It is understood that some patients will not fit the clinical condition contemplated by a guideline and that a guideline will rarely establish the only appropriate approach to a problem. 5 References 1. Fitch A, Everling L, Fox C, et al. Prevention and Management of Obesity for Adults.: Institute for Clinical Systems Improvement; Updated May 2013. 2. Arroll B, Goodyear-Smith F, Crengle S, et al. Validation of PHQ-2 and PHQ-9 to screen for major depression in the primary care population. Ann Fam Med. 2010;8(4):348-353. 3. Kroenke K, Spitzer RL, Williams JB. The Patient Health Questionnaire-2: validity of a twoitem depression screener. Med Care. 2003;41(11):1284-1292. 4. Ogden CL, Carroll MD, Kit BK, Flegal KM. Prevalence of childhood and adult obesity in the United States, 2011-2012. JAMA. 2014;311(8):806-814. 5. Finkelstein EA, Trogdon JG, Cohen JW, Dietz W. Annual medical spending attributable to obesity: payer-and service-specific estimates. Health Aff (Millwood). 2009;28(5):w822-831. 6. Jenkins TM. Prevalence of overweight, obesity, and comorbid conditions among U.S. and Kentucky adults, 2000-2002. Prev Chronic Dis. 2005;2(1):A08. 6