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Download Still - International Journal of Pharmaceutical Compounding
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MP SA VOLUME 15 NUMBER 2 Discontinued Drugs— Still Available? Loyd V. Allen, Jr., PhD, RPh Editor-in-Chief International Journal of Pharmaceutical Compounding Edmond, Oklahoma LE Over the past 50 years, thousands of drug products have been discontinued by manufacturers for a number of different reasons, including manufacturers going out of business, low sales, decisions to cut products, companies merging together and eliminating items that do not sell above a certain cutoff level, manufacturing problems resulting in excessive costs to continue manufacturing, and, in a few cases, the U.S. Food and Drug Administration’s (FDA) decisions concerning safety/ effectiveness. Regardless of the reason for discontinuing a drug, the problem is that physicians and patients no longer have access to the drug to which they have become accustomed and may be dependent. To overcome the problem involving drugs not removed by the FDA for safety/effectiveness, compounding pharmacists can continue to provide the medication for the physicians/patients if the active pharmaceutical ingredient (API) is available and if the technology involved in its preparation does not prohibit compounding. Some technology, including metered dose inhalers, transdermal patch systems, liposomal injections, dry powder inhalers, and some others, are not amenable to compounding. However, the majority of discontinued drugs can be compounded. Discontinued drug products that are unavailable can pose very serious problems that can even be life threatening for a patient or can result in chronic disabilities or a decreased quality of life. Pharmacists are trained to provide physicians and patients with needed medications in many situations. At www.CompoundingToday.com, the International Journal of Pharmaceutical Compounding provides a list of over 8,000 drugs that have been discontinued and, in many cases, their formulations are available. Pharmacists can periodically check this list and make plans accordingly to assist physicians and patients. The future will probably see more drugs being discontinued for a number of reasons, and many of these offer compounding pharmacists additional opportunities to be of service to you, the prescriber. For your convenience and informational purposes, we have included a noninclusive list of discontinued medications. Please note that only the brand name is presented here and each may have numerous dosage forms, some or all of which may be discontinued, some may remain on the market, and some may be available as generics. Please call your local compounding pharmacist for information on the availability of discontinued drugs that can be compounded for your patients. Example Drugs Withdrawn from the Market. Denorex Depo-Medrol Depo-Testosterone Desyrel Diamox Didronel Dilaudid Dimetane Diprolene Diuril Diutensin Dolophine Dolor Dolprn #3 Dorcol Dovonex Doxidan Dristan Durabolin Duracef Duragesic Dynacirc E.E.S. Edecrin Elavil Enduron Equagesic Ergomar EryPed Fergon Fiorinal Fiorinal with Codeine Fleets Flavored Castor Oil Floxin Fluonid Foille Forhistal Fostex Fototar Fungacetin Furacin Furadantin Furoxone Gantanol Gantrisin Garamycin Geocillin Geopen Grisactin Halcion Haldol Hibiclens Hibitane Histadyl Histaspan Hycodan Hydeltrasol Hydergine Hydromox Hygroton Ilosone Imodium Imuran Inderide Ismelin Isoptin Isopto Carpine Isopto Cetamide Isuprel Iverest Kantrex Kari-Rinse Kefzol Kenacort Kenalog Ketaject Kytril Lamisil Lariam Lasan Lasix Levsin Librium Liquiprin Lodine Loridine Lovenox Loxitane Marezine Maxaquin Maxidex Mellaril Mepergan Mesantin Metaprel Meted Midrin Mintezol Moban Monistat Mucomyst Mycelex Mycitracin Mycolog Mycostatin Mysteclin-F Naftin Nalfon Naphcon Narcan Naturetin Navane Nebcin Neo-Cortef NeoDecadron Neo-Delta-Cortef Neo-Hydeltrasol Neo-Polycin Neotrizine Nilstat Normodyne Novahistine Numorphan Oncovin Oruvail Otobiotic Pamine Panmycin Panthoderm Paredrine Pathocil PBZ Pediamycin Pediazole Pen-Vee K Pepcid Percocet Percodan Percogesic with Codeine Percorten Periactin Phenaphen with Codeine Phenergan Phenergan with Codeine pHisoAC pHiso-Dan Platinol Polaramine Poly-Histine DX Polysporin Ophthalmic Povan Pragmatar Prevacid Primatene Priscoline Pro-Banthine Proketazine Prolixin Propion Protropin Proventil Prozac Pyrroxate Quibron Quinamm Rapamune Rautrax-N Rectal MediconeHC Redisol Reglan Relafen Rezamid Rhulicaine Rhulicort Rhulihist Rifadin Risperdal Robaxisal Robinul Robitussin Romilar Rondec Roniacol Rose Bengal Ru-Hist Ru-Tuss Ru-Vert Sansert Seba-Nil Sebaveen Sebisol Sebulex Sebutone Septra Serax Sinequan Sinutab Skelaxin Sominex Sopronol Sotradecol Sparine Spectazole SpectroBid Spectrocin Stadol Stomaseptine Suby’s Solution G Sulfatrim Sultrin Sumycin Super-Anahist Suprax Surfacaine Surfadil Symmetrel Tagamet Tapazole Tedral Tempra Tenormin Terfonyl Terra-Cortril Terramycin Tetra-Bid Tetracyn Theelin Theofed Theoral Thiosulfil Thorazine Thru Ting Tofranil Torecan Tricodene Trilafon Trisoralen Tuamine Unipen Urecholine Vacuetts Vagitrol Valisone Vancocin Vasocon Vasodilan Vasotec Verequad Vermox Versed Vibramycin V-Cillin Vioform-HC Vistaril Vlemasque Vleminckx’ Voltaren Winstrol Wyanoids Zantac Zemo Zomax LE MP SA Achromycin Achrostatin Acnaveen Acne aid Acne-Dome Actidil Adriamycin Aldomet Aldoril Alupent Ambenyl Americaine Amiodarone Anacin with Codeine Anaspaz-PB Ancef Anectine Anspor Antabuse Antepar Anthra-Derm Antivert Apresoline Aralen Aramine Aricept Aristocort Artane Arthralgen Aspergel Atarax Aureomycin AVC B&O Baclofen Bactine Bactocill Bactrim Banthine Belladenal Bellergal Bendectin Bentyl Betalin S Biaxin Bleph-30 Brethine Brevital Bufferin with Codeine Bumex Buticaps Butisol Cafergot Calan Calcimar Calcitriol Calmol 4 CANASA Cas-Evac Ceclor Cefobid Cefotan Celestone Cerumenex Cetapred Chloraseptic Chloroptic-P Chlor-Trimeton Chymoral Claritin Clinoril Clistin Collyrium Coly-Mycin M Compazine Co-Pyronil Cor-Tar-Quin Cortef Cortisporin Ophthalmic Cotrim Cyclospasmol Cytoxan Dantrium Decadron Decholin Sodium Delalutin Deltasone Note: Please note that all these may not necessarily be available for compounding. Please call your compounding pharmacist for availability. RxTriad-A publication of the International Journal of Pharmaceutical Compounding. © 2012 IJPC. All rights reserved.
