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Treatment Protocol for ASD January 21, 2006 A Treatment Protocol for Autistic Spectrum Disorders (ASD) Dietrich Klinghardt MD, PhD My experience… 9 Treated numerous cases of children and adults diagnosed with conditions on the autistic spectrum successfully in both Europe and North America 9 Read the very practical information provided by www.DefeatAutismYesterday.org (Dana Gorman) 9 Read written material from the “Autism Research Institute” (ph) 619-281-7165 9 Studied a number of scientific papers on the subject 9 Carefully listened to my patients 9 Gained much knowledge from my own diagnostic technique, autonomic response testing (ART) – Joachim Mutter: Mercury and Autism: Accelerating Evidence. Neuroendocrinol Lett 2005; 26 (5): 439-446, Institute for Environmental Medicine and Hospital Epidemiology, University Hospital Freiburg, Germany. • Collaborated with me for many years and works at my Alma Mater in Freiburg, Germany. • E-mail: [email protected] 2 Dr. Dietrich Klinghardt 1 Treatment Protocol for ASD – January 21, 2006 Autonomic Response Testing • • • Every parent should learn it to help in the difficult daily decision making process Has helped to guide researchers world wide to look in the right direction Alternatives: EAV (i.e. MSA) – Current recommended lab testing for biochemical markers • • • Mostly only available to a wealthy elite Misguided in that it looks at the outcome of a toxic insult, not at the cause There is still no reliable in-vivo test that can determine the body burden of mercury or any other toxin • Has not led to the necessary political and judicial action – We have knowingly sacrificed numerous generations of children in order to protect the current corporate interests – Western countries are run by politicians who are mostly attorneys and not scientists – They have proven to be largely unable to understand scientific facts and findings and are unable to understand the urgency behind many issues. 3 With heavy emphasis on lab testing desperate parents are financing ongoing medical research on ASD that should be funded by medical schools and governments. The situation has turned moms into scientists and mental and biochemical heavyweights and turned them away from motherhood and playfulness, the very quality the children need to be nurtured and to recover. 4 Dr. Dietrich Klinghardt 2 Treatment Protocol for ASD January 21, 2006 The 5 A’s – In the German literature it is well established that 6 illnesses have the same underlying causes and respond to similar treatment strategies: • • • • • • Autism Allergies Atopic skin diseases Asthma ADHD Seizure Disorders – The treatment suggestions outlined in this paper can be applied to a large degree also to these six illnesses. 5 Common physical findings in ASD (all consistent with expected and reported findings of severe mercury toxicity) – Blocked “mirror-neurons” in frontal cortex (inability to respond to mom’s feelings, love, gaze, smile) – Inflammatory Bowel Disease – Increased size of frontal lobe and white matter – Cerebellar atrophy (reduced number of Purkinje cells) – Increased “neuronal packing” in cortex – Cytoarchitectural changes in subcortical structures – Micro-and astroglia activation with leaky blood brain barrier – Altered glutamate receptors – Hippocampal damage – Elevation of inflammatory cytokines in brain and CSF: MCP-1, IFNgamma – IgA deficiency and increased IgE – Lymphopenia – T-cell abnormalities – Abnormal NK cell function 6 Dr. Dietrich Klinghardt 3 Treatment Protocol for ASD January 21, 2006 Common energetic findings in ASD – – – – – – – – – – Energy body/soul displaced into the surrounding area near the physical body (huge energy field) Enhanced energetic perception (child knows what you are doing behind their back) Enhanced capability for telepathic communication Perceptions and communications cannot be received in, and down-stepped into, the physical body (function of tubulin, which is destroyed by Hg) Very responsive to properly used Energy Medicine applications Switching and blocked regulation Hyperactivity in most meridian systems Autonomic dysfunction Severe 2nd and 6th Chakra abnormalities Because of extraordinary energetic sensitivity the ASD child becomes recipient of unhealed transgenerational family issues (this perpetuates the illness) 7 The single cause of autism – Autism is a new man made condition – and therefore avoidable in the future – Occurrence and severity of autism is directly related to toxin exposure in a child with inadequate genes (those that code for detoxification enzymes) – Autism is not multifactorial: CNS-mercury plays the key single role in causing autism – 3 main sources of mercury toxicity… 8 Dr. Dietrich Klinghardt 4 Treatment Protocol for ASD January 21, 2006 Three main sources of mercury toxicity: 1. Thimerosal from vaccines, Rh-prevention (Rhogam), other medications • Autism and ASD is absent in the Amish community where children are not vaccinated. As soon as they do, they also become ill • Nigeria: the Bill and Melinda Gates foundation – – – – – Forced vaccinations with the help of GAVI (Global Alliance for Vaccines and immunization) onto African countries Amount of thimerosal, which was known to cause trouble in US children and outlawed in the US in 1999, was doubled in the vaccines for Africa pushed by Gates Since introduction of mass vaccine program in China an estimated 1.5 million children became ill with ASD since 1999. An unknown number of children (in the hundred thousands) in Nigeria alone developed ASD after forced vaccinations. There was no ASD in Nigeria before. Awareness of vaccine-ASD connection causing imprisonment and worse Corporate strategies involving other countries 9 Three main sources of mercury toxicity: Dr. Dietrich Klinghardt 2. Environmental (Environmental mercury release, special education rates and autism disorder: an ecological study of Texas. F.Palmer et al., Health and Place, Vol 12, Issue 2, June 2006, pp 203-209) ”on average, for each 1000 lb of environmentally released mercury, there was….a 61% increase in the rate of autism” 3. Mother (2/3rds of body burden passed on to child during gestation and breastfeeding) – Most biochemical, developmental, medical and behavioral findings in autism are secondary to mercury toxicity. 10 5 Treatment Protocol for ASD January 21, 2006 Synergistic factors (factors that increase toxic effects of mercury) – Testosterone: • Recent use of Lupron has successfully improved ASD symptoms (to lower testosterone in children with elevated levels). • I use a special preparation of a homeopathic homaccord of testosterone, which lowers testosterone naturally. • PC-SPES (several Chinese herbs) has been used successfully to lower testosterone in older male ASD patients. • Ground flax seeds (1-2 tbsp/day) in yogurt or cottage cheese are successfully binding hormone metabolites in the gut preventing reabsorption – Zinc has a well documented synergistic toxic effect with mercury (beware of too much zinc!) – All other toxic metals • Most researched is lead: an LD 1 of lead given to a group of rats (=the dose that is lethal to 1% of the rats in the group) at the same time with an LD 1 of mercury caused the death of all rats (LD 100). In mercury toxicology 1+1=100 – Most environmental toxins (recent papers on PBDEs, phthalates, bisphenol A) 11 Genetic polymorphisms and absent genes – Glutathione S-transferases (type M1 responsible for detoxifying many environmental toxins). • – Solution: enhance glutathione-SH production and availability: chlorella in high doses, NDF, alpha lipoic acid 25-50 mg every 6 hours 3 days on, 11 days off, methyl-B12 shots. Consider nasal glutathione drops/spray. Consider TD-glutathione on alternating non-DMPS days Methylation and related enzymes (COMT= enzyme responsible for breaking down unneeded neurotransmitters, MTHFR or methylene tetrahydrofolate reductase, MTRR or methionine synthase reductase). Consequence of reduced methylation capacity: reduced DNA methylation means: altered activity and function of proteins, altered neurotransmitter function, reduced synthesis of membranephosphatidylcholine • Solution: give BioPure Phospholipid Exchange ½ tbsp/day, use methylated B 12 (chlorella has highest amount found in nature) and methylated folic acid or folinic acid (there is need for hydroxyl-B12 and folic acid as well), adjust diet frequently using ART testing. Our homeopathic program is handling this issue beautifully (see below) – Sulfation genes (i.e: transsulfuration pathway depressed in ASD: low homocysteine, cysteine, methionine and glutathione) – Acetylation genes – Enzymes of cytochrome p450 pathway • • • Solution: use homeopathic sulfur (see below) Solution: use homeopathic program given below Solution: use homeopathic “Hepar comp” (see below) 12 Dr. Dietrich Klinghardt 6 Treatment Protocol for ASD January 21, 2006 Damages caused by Hg injury in ASD children – Enzymes: No researcher ever found any enzyme system in the body that has not been damaged by mercury. We have about 25,000 genes carrying the building plan for all of our enzyme systems. Together with epigenomic mechanisms each gene controls the manufacture of about 1,000 different gene variations. Some outcomes of mercury induced damage: • • • • • • • • • Whatever enzyme or system any particular researcher has ever looked at, there was Hgcaused damage. Much of it is reversible for quite some time Damaged blood brain barrier (astrocytes) with secondary toxic insults Defective gut barrier (leaky gut) with rapid food allergy development Developmental delay Changes in “mirror-neurons” of frontal cortex and limbic system Lack of clipping of non-serving dendritic connections Neurotransmitter dysfunction Maladaptation of every system( ie: poor nutritional intake) Blocks PPAR (peroxysome proliferators activator receptor): peroxysomes are cell organelles; they are the “liver” of the cell, responsible both for neutralizing toxic substances and for producing the special thing each cell is about: hormones in the hormone glands, bile in the liver cells, enzymes in the pancreas cells, etc. Recently the drug ACTOS has been used in ASD to increase the amount of peroxysomes produced in the cell. It has been overlooked, that chlorophyll (highest in chlorella) also induces the PPAR very effectively without the high cost and side effects of the medical drug. 13 Damages caused by Hg injury in ASD children (cont.) – The lack of central intelligent control of the immune system and the damage to aspects of the immune system itself leads to: • defective vigilance • failure to recognize self vs. other (autoimmune diseases www.MELISA.org) • inadequate response to invading microbes • failure to recognize microbial molecular mimicry • many other aspects of immune incompetence • this in turn leads to invasion of the system by opportunistic microbes and inability to respond to vaccine induced microbes appropriately 14 Dr. Dietrich Klinghardt 7 Treatment Protocol for ASD January 21, 2006 Most common opportunistic infections in ASD: – – – – – – – – Measles virus persistent in the intestinal tract Giardia and amoebas Roundworm, threadworms and tapeworms Herpes viruses Strep infections and consequences (chorea minor) Borrelia burgdorferi and co-infections (out of 8 recently tested children we found Bb IG-M positive in 7 with the Western Blot test) Molds and fungi Mycoplasma Helpful tests: Immunosciences (310- 657 1077) – Premier Autism Panel (measles, strep, viruses, Hg markers) – Multi-peptide ELISA test for Borrelia and co-infections – Mold Panel 15 The relationship between mercury and microbes – Microbial involvement is compartment specific: those areas contaminated with mercury are most immune compromised (absent immune surveillance in these areas) and become ideal breeding places for invading microbes. Compartmentalized Herpes viruses are known to be responsible for seizure foci in the brain in ASD children – Trying to eliminate the opportunistic microbes before reaching a reasonable degree of toxin elimination in the involved area is not possible. – Antibiotic, nutrient and herbal uptake in a toxin contaminated area is only minimal and will ultimately not succeed. – Most important long term strategy: decontaminate the most crucial areas in the CNS before attempting major antimicrobial strategy There is no cure of autism without eliminating the different forms of mercury from most body compartments. 16 Dr. Dietrich Klinghardt 8 Treatment Protocol for ASD January 21, 2006 Is it not enough to eliminate the mercury then? Mercury is the match that ignited the forest fire (multiple biochemical aberrations). It is not enough to extinguish the match if you want to stop the forest fire – once it is burning. A lot more action on different fronts is needed. – Elimination of all synergistic toxins – Recognition and activation of defective enzyme systems – Identifying and treating the 7 perpetuating factors: 1. 2. 3. 4. food allergies systemic family issues and early psychological/emotional trauma ongoing toxin exposure (mold, carpet floors, etc) unhealed focal areas or interference fields: umbilical scar, circumcision scar, head trauma from birth, chronic intestinal inflammation, tonsil infection 5. geopathically disturbed sleeping location and electrosmog 6. defective dentition and facial development of head/neck/jaw structure 7. persistent chronic stealth infection 17 Klinghardt Autism Protocol Five steps: 1. Symptomatic relief (with every non-invasive method currently available) 2. Identify and treat/eliminate all 7 risk factors 3. Decontaminate: identify and decontaminate compartmentalized mercury, environmental, mycoand other toxins 4. Treat: identify and treat opportunistic infections 5. Restore damaged nervous system, immune system and gastrointestinal tract 18 Dr. Dietrich Klinghardt 9 Treatment Protocol for ASD January 21, 2006 I. Symptomatic Relief What to eat and what not to eat: Best: ART or MSA testing for all foods. Should be done once/month to adjust for rapid changes 2nd best: therapeutic 14-day food elimination trial 3nd best: Coca pulse test (whenever possible) 4th best: lab testing: IgG, ELISA-Act for delayed reactions, food sensitivity panel from Carbon-Based Corporation (needs all 3 to get close to the truth) 19 I. Symptomatic Relief What to eat and what not to eat: – Common sense diet: eliminate all grains (especially gluten containing barley, rye, oats, wheat and spelt (b.r.o.w.s), all cow dairy, all soy, all corn, all nonorganic food) – Specific carbohydrate diet (avoid disaccarides – use only monosaccarides) – based on observation that Hg has destroyed ability to make enzymes that digest disaccarides (disaccaridases) – Give enzymes at the end of each meal (digestive enzymes are ph dependent and work in alkaline environments. The Ph in the stomach is 1.5 before eating and 4.5 at the end of a meal - much more alkaline) – Use HLC MindLinx probiotic (Pharmax): Lactobacillus crispatus (CLT221) and Lactob.rhamnosus (CLT341) degrade exorphins from casein and gluten (1 cap or 1/4tsp with each meal) – If still breastfeeding: continue, but have mom take 10 tabl BioPure chlorella 3-4 times per day to clear toxins from milk 20 Dr. Dietrich Klinghardt 10 Treatment Protocol for ASD January 21, 2006 I. Symptomatic Relief What to eat and what not to eat: – Formulas: Non-dairy (Neocate) or predigested (Alimentum, Nutramigen) Give the child chlorella (tablets to chew – more is better. Swiss mothers have reported complete resolution of their children’s autism by giving 120 or more tablets chlorella/day. Kids either love it or hate it) Use Beta-Glucan based probiotic from BioPure on and off Super Baby Foods Cookbook – – – 21 I. Symptomatic Relief The Biomedical approach: – Vitamin B6 (Bernard Rimland: “Autism Research Review international” Vol 1, No4, 1987): • • At least 21 papers show benefits in autism when given in high doses: 300-500 mg/day or 30 mg/kg/day as pyridoxalHCL. I like to do a 6 week trial. If client has no beneficial response during that time I continue to give closer to normal doses for the entire length of treatment time. Given as P-5-P may need lesser dose Seizure control: 300 mg B6/kg/day (Pietz) 22 Dr. Dietrich Klinghardt 11 Treatment Protocol for ASD January 21, 2006 I. Symptomatic Relief The Biomedical approach: – When using B6 approach, obligatory: • • Magnesium Citrate : 400 mg /day or at least 25% of mg dose of B6 or at least 10 mg/kg body weight Zinc ( I only recommend low dose supplementation because of synergistic effect with mercury). Always use some copper when using zinc long term. Copper is needed to fight infections. Recent copper-phobia based on misunderstanding of hair and element analysis (copper used up by immune system appears displaced in hair and aging red cells) B-6 overdose is rare but has to be recognized when not using ART testing. Leads to easily reversible neuropathy recognized by: -Child shakes hands as if to get circulation back -difficulty picking up objects such as foods -difficulty walking because of numbness on bottom of feet 23 I. Symptomatic Relief The Biomedical approach: – Vitamin C : 100 mg/kg minimum (ARRI 6/1) – B-complex: many children respond poorly to the available products. I recommend high doses of pantothenic acid, niacin and B2 only – or nutritional yeast if tolerated 24 Dr. Dietrich Klinghardt 12 Treatment Protocol for ASD January 21, 2006 I. Symptomatic Relief The Biomedical approach: – B 12 and folic acid: there has been great controversy regarding B 12 and folic acid. Recently folinic acid or methylated folic acid (L-5-methyl-tetrahydrofolate) have been recommended over folic acid. Dana Gorman (and us) find folic acid in combination with hydroxy-B12 (5:2 ratio) more commonly helpful when given at the same time sublingually several times/day. It is best to use ART testing to find which form of folic acid is the right form for this particular patient today • • Folic acid: de-methylates toxic substances Hydroy-B12: has been found to remove toxic nitric oxide compounds from brain Multi-mineral supplement in high doses (M.Gentile) Dimethylglycine: using 125 mg tablets: start with ½-1 tabl 4 times/day. Increase dose until stimming/regression improves. Give next dose when effect lost. Up to 20 tabl/day in divided doses 25 I. Symptomatic Relief The Biomedical approach: – Methyl-B12 (J.Neubrander) 64.5mcg/kg given subcutaneously once every 3 days (takes often several months before showing positive results) use 25 mcg/ml concentration Other recommended supplements: • • • • • • • Calcium citrate 600-1200 mg/day Fish oil (Nordic Naturals): 2 tsp/day Udo’s Oil: 1-2 tsp/day Folinic acid (if it tests better then folic only): 8001600mcg/day Vit E <5 years: 200/day >5 years: 400/day Vit A (use Biotics emulsion): 5000-7500/day Selenium: 200mcg/day 26 Dr. Dietrich Klinghardt 13 Treatment Protocol for ASD January 21, 2006 I. Symptomatic Relief The Biomedical approach: – Low dose Naltrexone (LDN): start with 0.1 mg at bedtime and work up to 4.5 mg if no effect is seen. Immune modulation. Significant symptom reduction in over 50% of ASD children – Blue light: if hyperactivity is part of the picture, wearing blue glasses or using a blue lightbulb (with the Dinshah method or simply in the light fixture in the child’s primary room) – Read the advice given by Dana Gorman www.DefeatAutismYesterday.com 27 II. Identify and treat/eliminate the 7 risk factors 1. Food allergies – I know how difficult it is already to feed a healthy child. Feeding an ill child and having lots of food restrictions can be a nightmare. Stretch and try your best. And: compromise. Don’t drive yourself nuts. Food allergies and sensitivities change rapidly in the ASD child, especially during Hg detox. We use ART (or MSA) as a fast low cost predictor of the most suitable food at this particular time. The available lab work is cumbersome, unreliable (see papers by Dr Alan Gaby MD) and very expensive. ART has been reliable and extremely helpful and can be learned by any mom or dad. I suggest that the family only buys food that is ok for the autistic child and not have any of the forbidden foods in the house. As the child improves so will the food sensitivities. They are not the cause but a symptom of the illness. The details of the Specific Carbohydrate Diet are published in the DAN protocols. I recommend the rotation diet, which was first made public by Sally Rockwell. Metabolic typing and the blood group diet have been helpful tools in some, not all patients. Because of the gluteo-morphin and caseo-morphin issue cow dairy and gluten should not be eaten, even if there is no allergy. ART testing is a more reliable predictor: if yogurt or Swiss cheese test ok, they can be eaten without adverse effects (on that day). – – – 28 Dr. Dietrich Klinghardt 14 Treatment Protocol for ASD January 21, 2006 II. Identify and treat/eliminate the 7 risk factors 2. Systemic family issues and early psychological / emotional trauma – Unresolved transgenerational trauma predisposes to childhood diseases including autism. Some insights are communicated in my paper on the 5 levels of healing (www.neuraltherapy.com). Often therapy and biomedical intervention does not progress until a family healing constellation has been done by an experienced therapist. Unresolved trauma in the child’s ancestry creates a disturbance in the field which will filter down into the child’s psyche, nervous system and metabolic functioning. It is never too late to heal wounds from the past. The constellation work is unique: the therapy can be done for the child by any living family member 29 II. Identify and treat/eliminate the 7 risk factors 3. Ongoing toxin exposure (mold, carpet floors, plastics from bottled drinking water, flouride, further vaccinations, toxic bedding, etc) – Every parent of an autistic child should be asked to organize an “indoor air quality inspection” by an expert in the field. Often we find significant mold levels in homes, insufficient ventilation, polluted crawling spaces that leak toxic gases into the indoor environment, outgasing of volatile organic compounds (VOCs) from carpet floors or toxic building materials and many other problems that have synergistic effects with mercury in the brain. We also saw children becoming ill after the neighborhood was sprayed by government licensed pest control efforts or after the toddler/childcare facility was re-carpeted or started using TV dinners for the children which were microwaved in their respective plastic containers. Use Carbon Based Corp urine test for solvent/plastic metabolites. 30 Dr. Dietrich Klinghardt 15 Treatment Protocol for ASD January 21, 2006 II. Identify and treat/eliminate the 7 risk factors 4. Unhealed focal areas or interference fields – Umbilical scar, circumcision scar, head trauma from birth, chronic intestinal inflammation, tonsil infection and other scars. Scars and traumatized body parts create abnormal input into the ANS with resultant adverse multi-system effects Chronically infected tonsils are often a major contributing problem in brain inflammation/autism (Review paper on my web site www.neuraltherapy.com) Degenerated tonsils often house multiple bacterial and viral colonies and produce potent brain neurotoxins Be prepared that currently ENT doctors often do not believe that tonsil infections are problematic - and resist performing a tonsilectomy Chronic intestinal infections and infestations create a gutinterference field which has to be adressed energetically, biologically and biochemically – – – – II. 31 Identify and treat/eliminate the 7 risk factors 4. Unhealed focal areas or interference fields Diagnosis: – Immunosciences Autism Panel tests for anti-strep antibodies – We also use the chair-side dental test for thioethers developed by Boyd Haley (www.ALTcorp.org) on the tonsils. It will often show high levels of toxicity. Treatment: – Trial with Sanum remedies: Pleo SanPseu, San Strep and Pleo Not 5 drops 3 times daily for 6 weeks followed by Pleo Sancom drops twice daily for 1 year – or direct injection with neural therapy technique into the tonsils – Use Tonsilla comp from Heel 1 oral vial once weekly for 1-2 years (multiple other benefits) • • regenerative cryotherapy (Dr. Sergej Dorochov, www.kryopraxis.de) conventional tonsilectomy 32 Dr. Dietrich Klinghardt 16 Treatment Protocol for ASD January 21, 2006 Tonsilla compositum suis organ hormone nosode – – – – – – – – – – Acidicum ascorbium D6 Glandula lymphatica suis D8 Tonsilla suis D28 Medulla ossis suis D10 Funiculus umbicalis suis D10 Splen suis d10 Hypothalamus suis D10 Hepar suis D10 Embryo suis D13 Cortex glandulae suprarenalis suis D13 – – Cortisonum aceticum D13(Catalyst) Levothyroxinum D13 – – Pyrogenium nosode D 198 Psoriasis nosode D28 II. – – – – – – – Pulsatilla D6 , Conium D4 Galium Aparine D6, Aesculus D6 Echinacea Angustifolia D4 Tartarius stibatus D6 Dulcamara D4,Coccus Cacti D6 Gentiana Lutea D6 Geranium robertanium D6 – – – – – – Ferrum Phos phoricum d10 Calcium Phosphoricum d10 Merc. Sol Hahn. D13 Sulfur D8 Baryum Carbonicum D28 Acidicum Sarcolacticum D6 plant mineral 33 Identify and treat/eliminate the 7 risk factors 5. Geopathically disturbed sleeping location and electrosmog – ASD children are electro-sensitive and cannot tolerate abnormal electric fields from cordless phones, faulty wiring in home, head end of bed too close to electric outlet or wiring in wall, wireless internet, close-by cell phone tower/transmitter or radio tower Diagnosis: – best: exam by Building Biology trained expert (Robert Steller) – inspection by local electrician – ART testing Treatment: – demand switch or disconnect fuses for every outlet in child’s bedroom walls – buy chorded phones for home or disconnect cordless phone at bedtime – no wireless internet – inspect neighborhood for cellphone microwave emitters – move house if needed Dr. Dietrich Klinghardt 34 17 Treatment Protocol for ASD January 21, 2006 II. Identify and treat/eliminate the 7 risk factors 6. Defective dentition (occlusion) and facial development of jaw structure – – Evaluation and tx by cranial osteopath (D.O.) Cranio-sacral therapy (be aware of large quality differences between practitioners) See experienced older orthodontic biological dentist (Dr. Dino Paulos, Victoria, Dr. Ara Elmajian, Vancouver, Dr. F.Robeson, Tacoma WA) – – Read book: “Dental Distress Syndrome” by Al Fonder 35 II. Identify and treat/eliminate the 7 risk factors 7. Biochemical and nutritional deficiencies – This is referred to today as the “Biomedical Approach” and has been the focus of the teaching of DAN, DAY and most other organizations Most rewarding is the diagnosis and tx of mineral deficiencies (ART, MSA, red cell minerals, hair analysis) and fatty acid disorders (red cell membrane fatty acids/Patricia Kane, PhD) Mercury affects every aspect of biochemistry. Without addressing the Hg toxicity at the deepest level, no permanent progress is made with the biomedical approach – – 36 Dr. Dietrich Klinghardt 18 Treatment Protocol for ASD January 21, 2006 III. The ethyl mercury elimination protocol Once ethyl mercury is introduced (as thimerosal) into the body via injection, it is picked up by unmyelinated nerves and travels inside the axons of the nerves in less then 24 hours to the spinal chord – In another 24 hours it reaches the brain, where it is initially taken up by the astrocytes. They become ill and start failing in one of their most important jobs: to create the blood brain barrier http://missinglink.ucsf.edu – 37 III. The ethyl mercury elimination protocol – Later the Hg is taken up by all protein molecules inside the brain and brain-cells: GAGs in matrix, receptors on cell walls, enzymes, structural molecules, GTP, the enzyme which creates tubulin (see article by Joachim Mutter), enzymes of the citric acid cycle inside the mitochondria, etc. www.lbl.gov Dr. Dietrich Klinghardt 38 19 Treatment Protocol for ASD January 21, 2006 III. The ethyl mercury elimination protocol – The main volume of mercury is trapped in the connective tissue of the muscles, bones, ligaments outside the CNS. Magnified 100,000 times Magnified 50,000 times 39 III. The ethyl mercury elimination protocol – It is also trapped in the lymphatic tissue and adipose tissue – Overall, only a small amount reaches the brain. This amount is responsible for most symptoms http://education.yahoo.com 40 Dr. Dietrich Klinghardt 20 Treatment Protocol for ASD January 21, 2006 III. The ethyl mercury elimination protocol Principles of detox: 1. The order • Clear the emunctories (excretory organs) first of mercury and other toxins (Heel remedies are ideal) Remove the bulk of Hg first which is not bound in the CNS (iv DMPS and Vit C, DMSA orally, DTPA, chlorella are ideal) Remove the brain-Hg last (transdermal DMPS, oral cilantro, microcurrent) • • 41 III. The ethyl mercury elimination protocol Principles of detox: 2. The chemistry • Hg is bound in different molecular arrangements: – – – • • • • metallic Hg (only in fatty tissue) inorganic salts (connective tissue) organic molecules (methyl, ethyl and phenyl mercury) There are virtually dozens or hundreds of differences how Hg is bound in the tissues, inside cell structures and organelles No single detox agent can address all forms of Hg in the body. A good program uses sequentially different agents. Essentials: – – – A protein rich diet corrected for blood type (D’Adamo), metabolic type (Wolcott) and food sensitivities. Mineral supplementation to compete with toxic metals at binding site (liquid minerals from Melanie Gentile PhD). Correct for all known or suspected vitamin/nutrient deficiencies 42 Dr. Dietrich Klinghardt 21 Treatment Protocol for ASD January 21, 2006 III. The ethyl mercury elimination protocol Principles of detox: 3. The program: • • • • Give BioPure chlorella to detoxify the intestinal tract ( 2 weeks) – 10-60 tbl 3 times/day. After 2 weeks reduce dose to 8 tbl 3 times/day. Include NDF 10 drops twice a day in water for 2 months or the entire length of program Add matrix electrolyte to all drinks and to food (2 tbsp/day) From day 1: give 1 tsp BioPure Phospholipid Exchange (Alpha-lipoic acid, Magnesium, EDTA and Phospholipids) After 4 weeks add: 2-10 drops cilantro (BioPure) in hot water at bedtime. Rub 5 drops into wrists and 5 drops into ankles twice daily (front and back). 43 III. The ethyl mercury elimination protocol Principles of detox: 3. The program: • • • • • (cont.) Ideal: use “Toxaway” foot bath from BioPure 3 times per week to activate the detox related ANS functions (often dramatic initial results) After another 2 months start TD DMPS: 1.5 mg/kg body weight every other day (rub into most soft skin areas: front of neck, wrists and ankles are best, in boys also scrotum). Always pause any of the detox agents when patient aggrevated/worse until crisis is over. Focus on homeopathics during crisis. After 6 months, consider TD-DMSA. TD EDTA has not shown any results in my experience Consider glutathione inhalation or nasal spray (Key pharmacy, Kent, WA). Oral glutathione has only a local effect in the gut and a placebo effect 44 Dr. Dietrich Klinghardt 22 Treatment Protocol for ASD January 21, 2006 IV. Treating infections and infestations Primary advice: first treat, then try to confirm diagnosis. This is especially true for Lyme Borreliosis. – Worms: • • Vermox 100 mg twice daily for 3 days, repeat after 21 day pause Often needs follow up treatments. Biltricide is most effective at high doses (30 mg/kg body weight 3 times per day on day 1, 20 mg/kg day 2 and 10 mg/kg day 3, repeat after 21 day pause). – Giardia/amoebas: • Tinidazol. 75 kg Adult dose: 500 mg twice daily for 10 days. • Adjust dose according to body weight but stay on the high side. • Follow with BioPure freeze dried garlic 1-2 caps after each meal 3 times/day for 2-3 years or for good 45 IV. Treating infections and infestations − Bacterial/fungal/mycoplasma: – Intracellular microbes: • • • BioPure Noni: start with full dose: 2 drops per year of age twice daily in glass water. • Reduce dose during Herxheimer reactions • Lab testing for Lyme and co-infections can be done successfully after 8 weeks of continuous treatment (IgeneX lab in Palo Alto, Cal) www.lymelink.com • BioPure Samento: start with 2 drops in glass water once daily If no worsening (=Herxheimer reaction) increase slowly to 2 drops per year of age twice daily to a maximum of 1 dropper full twice daily Treats most known extracellular microbes Dr. Dietrich Klinghardt 46 23 Treatment Protocol for ASD January 21, 2006 IV. Treating Infections Mold – Many homes in the US have elevated levels of mold (aspergillus, cladosporium, stachybotrys) caused by poor building plan and materials – Have indoor air quality inspection – Use propolis room vaporizer (kills most known indoor molds, bacteria and viruses) – Use matrix microbes in spray bottle and spray entire home twice weekly (competing healthy microbes which create a health inducing milieu) – Fluconazole and Nystatin orally 47 IV. Treating infections and infestations – Viral infections (HSV 1, HHV 6, EBV, VZ, CMV) respond excellent to management with Heel homeopathics – Measles: • • • 400,000 units Vit A palmitate in 3 divided doses for 2 consecutive days only. Repeat after 6 months, then once yearly Also works on other viruses (HPV, etc) Guidelines published in “Biomedical assessment options for children with Autism and related problems” by J Pangborn and S Baker, Autism research Institute, 4182 Adams Ave, San Diego, CA 92116, Oct 2002 edition, pp 216-220 48 Dr. Dietrich Klinghardt 24 Treatment Protocol for ASD January 21, 2006 V. Healing the damage 1. Neurodevelopmental therapies Best time: earlier is better - but child may not be ready to participate. Has to be included no later then 9 months into program – Ed Snap: creating an intrauterine environment to regress the neurons to a stage where everything was and still is possible. Dramatic results – Color therapy: College of Syntonic Optometry or Dinshah method – Sound therapy: Tomatis therapy or “bastardized” versions of it: the listening program – EEG biofeedback – Newer techniques involving touch, movement and sensory stimulation of all kinds 2. Homeopathy (see above) 3. Live cell therapy (available only in Canada, offshore and in Europe) 4. Stem cell therapy (available in Mexico, soon also in Nevada) 5. Treat mom and dad for PTSD 49 The synergistic use of homeopathic medicine in the treatment of ASD – ASD cannot be healed with the biomedical approach (=supplements and drugs) alone. It has failed. My teacher in homeopathy, the late Gerhard Koehler MD, PhD made a simple observation. – There are 3 types of healing agents and methods: • Suppression therapies: anti-inflammatories, anti-biotics, anti-fungals, anti-tumor agents, etc • Substitution therapies: insulin, thyroid hormone, minerals, etc • Regulation therapies: homeopathy, herbs, neural therapy, acupuncture – Illnesses can only be lastingly healed, if the self-regulation of the system is fully restored and fully functional. This cannot be achieved with suppression methods or substitution methods. It can only be achieved with regulation medicine. The leading treatment is, and always was, homeopathy. 50 Dr. Dietrich Klinghardt 25 Treatment Protocol for ASD January 21, 2006 The synergistic use of homeopathic medicine in the treatment of ASD Homeopathy Basics: There are 2 fundamentally different approaches used in homeopathy today. 1. Classical Homeopathy • • • Uses single remedies Remedy is determined by repertorizing Advantage: works on 1st, 2nd and 3rd level. Most elegant healing method, if it succeeds (today rather an exception) • Disadvantage: takes many years of training and experience. Most advanced and alive “culture” of classical homeopathy is found today in India and Germany 51 The synergistic use of homeopathic medicine in the treatment of ASD Homeopathy Basics: 2. Reckewegs Homotoxicology • • • • • • • Uses multiple synergistic remedies - which are focused around a particular medical theme - at the same time (combination formulas) Its use can be based on Western diagnostic systems Very effective Requires little training to use correctly Very safe to use Most advanced development: the formulations by Dr Reckeweg (Heel/BHI) Disadvantage: – – Almost no effect on higher levels of consciousness Not respected by classical homeopaths 52 Dr. Dietrich Klinghardt 26 Treatment Protocol for ASD January 21, 2006 The synergistic use of homeopathic medicine in the treatment of ASD 3 carriers of homeopathic healing energy: 1. Liquids (water alone, or water plus alcohol or saline or minerals) – Advantage: holds the energy very strongly for up to hundreds of years – Disadvantage: • When kept in plastic bottles, becomes contaminated with Phthalates, Bisphenol A and Dioxin. More expensive to mail. When alcohol is used, may interfere with religious beliefs (people that have succeeded in AA) or belief that it may cause growth of intestinal yeast. Some folks have a true alcohol allergy. When no alcohol is used, bacterial or yeast growth may occur over time depending on source of material. No difference in the different solutions regarding how long information is stored. Heel offers multiple dose bottles in water/alcohol base (35Vol % ethyl alcohol) and oral sips (“single-dose-vials”) which are water or saline based without alcohol. The single dose vials are approved in Germany and most civilized countries for injection in humans and animals. In the US injection of these remedies would constitute an “off-label” use. • • • 53 The synergistic use of homeopathic medicine in the treatment of ASD 3 carriers of homeopathic healing energy: 2. – Sugar pellets (lactose) Overwhelming disadvantages: • • Hold energy of original remedy in the water coat surrounding all sugars in temperate climates, not in the actual sugar. Energy is weaker then the energy in liquid-based remedies All homeopathics available in US health food stores (Boiron, Sanum, BHI, Heel) use lactose in their homeopathic tablets or pellets. Lactose is a di-saccaride. Autistic children commonly have a lactose intolerance or allergy (defect in di-saccaridases). Lactose based homeopathic preparations are not suitable for use in autism. The DHU remedies (Deutsche Homeopatische Union) - which to my knowledge are not available in the US are the only “dry” classical homeopathic pellets that use a nonallergenic easy to digest mono-saccaride 54 Dr. Dietrich Klinghardt 27 Treatment Protocol for ASD January 21, 2006 The synergistic use of homeopathic medicine in the treatment of ASD 3 carriers of homeopathic healing energy: 3. Energy medicine applications: • • • • Audio/video tape (magnetized metals) Superimposed on pulsed microcurrent (KMT technology) Homeopathic “information” superimposed on laser beam, sound, magnetic field or other EM-carrier Digital information stored on computer 55 The use of Heel remedies in ASD – Only the oral sips are universally acceptable and ideal for all ASD patients (see previous) – Some important remedies are only available as alcoholic tincture or lactose based tablets (advantages have to be weighed carefully) – Use 20 minutes away from all food or drinks. If different homeopathic remedies are given orally at the same time, separate by 30 seconds – All available remedies have their appropriate place and time in the management of the typical ASD patient – I will give “recipes” from my office which have often been very helpful and are filling an important, but often overlooked, therapeutic gap 56 Dr. Dietrich Klinghardt 28 Treatment Protocol for ASD January 21, 2006 Why use the Heel remedies? ¾ Abundant and intelligent literature/learning support ¾ Easy to understand, use and integrate into an existing ASD program ¾ Regulation medicine is absolutely necessary to achieve long term results. Missing in most current DAN protocols ¾ Heavy metal detox in the brain can only be achieved by including regulation medicine into the program ¾ Does not need expensive long training to achieve excellent results (I have taught the use of the remedies to hundreds of practitioners in a few hours, who then went on and became experts in applying the remedies with excellent results in their programs) ¾ Inexpensive ¾ Safe and with no serious side effects ¾ Even the consistent use of the “wrong” remedies leads to improved ability of the system to self-regulate (vast German body of research) 57 How to target different tissues or body compartment? Homeopathics act most strongly on the germinal layer or in the system where they are introduced – Skin and brain are derived from ectoderm, the same embryonic layer. To reach the brain, the most profound effect is achieved by injecting the remedy into the surface 2 mm layer of the skin or using a transdermal cream (such as TD-DMPS). Sniffing (or dropping) the remedy up the nose (olfactory nerve and parasympathetic nerves connected to brain) is also effective. Example: Thalamus comp – If the Endoderm is to be reached (gut and appendages) it is best to swallow the medicine Example: Nux vomica Homaccord – If the mucous membranes are to be reached it is best to introduce the remedy simply into the oral mucosa (“sublingual application”) Example: Mucosa comp – If the lymph nodes of the intestinal tract are targeted, it is best to inject the remedy into the tonsils which govern the GALT (gut associated lymphatic tissue) Example: Lymphomyosot – If the Lymph nodes of the mediastinum are targeted (ie in asthma), the first “respiratory” lymph node group should be injected: the adenoids, Every application outside this system is less effective, but often the next best choice. The proper applications are taught in the courses of the Amercian Academy of Neural Therapy. Most US practitioners use homeopathics only orally with some results. 58 Dr. Dietrich Klinghardt 29 Treatment Protocol for ASD January 21, 2006 Autistic Spectrum Disorders: Basic Homeopathic Support Program General remarks: – Since most clinical tips here are recommending the use of the “single dose vials” and this paper is intended for both the European community and the US health care providers, the following instructions are generally to be followed. Notice, that the doses I recommend in ASD are much lower then the doses suggested for use in the general population (decreased ability to process and excrete mobilized toxins). They might be increased to the doses recommended in other writings as the patient improves. 59 Practitioners outside the US: – Inject 1 amp once weekly s.c (27 g/1/2”needle) – Or follow specific neural therapy recommendations for• intra-cutaneous use when treating brain and skin • subcutaneous use when addressing matrix of ground system/extracellular space • special injection techniques into acupuncture points, ganglia and glands when targeting the ANS or hormone system 60 Dr. Dietrich Klinghardt 30 Treatment Protocol for ASD January 21, 2006 US Practitioners: Most Heel oral sips contain 1.1 ml of remedy – Draw up the content of 2 vials with 21 g 1” needle into a 3 ml syringe (best: glass syringe) – squirt into small dropper bottle. Use 10 drops once daily, 5 days on, 2 days off (give entire left-over amount from dropper bottle on day 5). – If the bottle appears empty before day 5, fill up dropper bottle with filtered water, tap 50 times and keep using as before till day 5 (the residues on the glass-wall are enough to create an LM potency of the medicine which enhances the effect in an often almost magical way). – Keep the remedies initially in separate dropper bottles to be able to experiment with dosages/frequency of application (exactly as you already experiment with your vitamins and medications). – Later: remedies which are taken in the same pattern can be mixed together and a bottle can be prepared with a 1-week supply. If you observe that a remedy seems to have a positive effect but stops to work after less then 24 hours, consider giving 10 drops every 12 hours (or more often) 61 Step #1: “only fools rush in”(Elvis Presley): organize lymphatic and organ drainage before triggering a dumping of mercury and other toxins from their hiding places 62 Dr. Dietrich Klinghardt 31 Treatment Protocol for ASD January 21, 2006 Lymphomyosot® D12 D6 D5 D4 D3 Myosotis Gentiana Juglans Levothyroxin Ferrum Pinus Scrophularia Fumaria arvensis lutea jodatum silvestris nodosa officinalis Teucrium Sarsaparilla Natrium Geranium Veronica Equisetum Calcium Aranea scorodonia sulfuricum robertianum hiemale phosph. diadema Single Homeopathic Remedies Lymphomyosot: give continuously throughout program. Enhances lymph drainage from matrix and stabilizes thyroid. Best injected into submandibular lymph nodes or tonsils. Second best: oral drops 63 Ingredients Oral Vials Histaminum 12x, 30x, 200x Tablets Histaminum hydrochloricum 12x, 30x, 200x Characteristic Symptoms Support of detoxification; eczema; allergies Support of detoxification; eczema; allergies Histamin: give 5 drops before each meal – prevents food sensitivities very effectively. Try during stimming or regression reactions – decreases brain inflammation often rapidly. Try early on for every crisis. Very effective! 64 Dr. Dietrich Klinghardt 32 Treatment Protocol for ASD January 21, 2006 Berberis Homaccord PPG MPG CPG IPG 200 30 20 10 0 Colocynthis Berberis vulgaris Veratrum album Berberis Homaccord (kidney drainage) give throughout metal detox. Best: as segmental therapy over the kidneys. 2nd best: 10 drops in glass water. May need to give 3 doses per day during detox-crisis. Use during entire length of program. 65 Hepar compositum D28 D13 D10 D8 D6 D4 D3 Chelidonium Carduus marianus China Lycopodium Hepar Vit. B12 suis Cynara scolimus Veratrum Taraxacum Avena sativa Orotic.Ac CholesteCalc.Carb rinum Pankreas Acidum Sulfur suis fumaricum Colon Histamin Natrium Ac suis Duodenum suis oxalaceticum Lipoic Vesica Acidum Fel fellea Acidum DL-malicum tauri suis a-ketogl. Thymus suis Hepar comp: give 2 weeks on, 1 week off during detox phase of program (1st 2 years) 66 Dr. Dietrich Klinghardt 33 Treatment Protocol for ASD January 21, 2006 Ingredients Sulphur 6X Thuja occidentalis 6X Vaccinotoxinum 8x Bufo rana 10X Psorinum 10X Medorrhinum 12X Natrum muriaticum 12X Syphilinum 12X Oleander 4X Cicuta virosa 5X Bacillinum 12X Characterisitics Itching, burning skin, worse from scratching Warts, carbuncles, brown spots on hands and arm Chronic eczema Itching and burning skin, pain runs up arm Intolerable itching, seborrhea Intense and incessant itching, worse at night Greasy skin, eruptions in blends of limbs, alopecia Reddish-brown eruption with disagreeable odor Very sensitive skin with bleeding, oozing eruptions Eczema without itching, chronic impetigo Ringworm, eczema of eyelids Psorinoheel: contains 3 miasmatic remedies (inherited weaknesses) except TB. Also contains thuja, an important vaccine antidote Give 10 drops twice/week for entire duration of treatment. Exception: use oral drops in alcohol if possible, not single use sips (only the “alcoholic drops” have syphilinum, which is most important). 67 Step# 2: Start metal detox program (after 2 months). Use TD DMPS, cilantro, fish oil, chlorella and other agents along with the following homeopathics… 68 Dr. Dietrich Klinghardt 34 Treatment Protocol for ASD Ingredients Sulphur 4X, 6X, 12X, 30X, 200X January 21, 2006 Characteristics Skin dry, scaly, unhealthy; great itching and burning, worse from scratching and washing; pruritus from warmth; hot, sweaty hands Schwef Heel: mobilizes mercury and all other toxins from their protein binding sites. Expect powerful increase in detox symptoms and positive long term effects. Start with 1 drop/day. Increase every 3 days till on 10 drops/once per day. Do not use during detox or Herxheimer reactions (not on days when patient clearly worse, which will happen!) 69 Ingredients Thuja occidentalis 4X, 12X, 30X, 200X, 1000X Characterisitics warts; polyps; carbuncles; herpetic eruptions sensitive to touch Thuja forte: universal vaccine antidote. 5 drops every other day for 3 months. Eliminates toxic vaccine residues and activates blocked detox enzymes 70 Dr. Dietrich Klinghardt 35 Treatment Protocol for ASD January 21, 2006 Step # 3: help the cells to wake up and regain their intelligence (and their ability to communicate and clear themselves of toxins) Wait 8 weeks (into program) before starting. 71 Thalamus compositum 10 10 10 8 8 MPG PPG CPG IPG 8 6 6 4 2 Gland. Suprarrenalis Thalamus opticus Pineal suis AMPc IPG Viscum album 0 MPG Thalamus Comp: contains healthy organ extracts of all major glands in brain and cAMP, which is needed for communicating incoming messages to the interior of each body cell. cAMP and cell wall communication is disturbed in all ASD patients. One amp/week for 3 months. Best: 3 drops into each nostril twice daily: 5 days on, 2 days off. 72 Dr. Dietrich Klinghardt 36 Treatment Protocol for ASD January 21, 2006 Coenzyme compositum – Contains catalysts/enzymes of the citric acid cycle (CAC) in the mitochondria. The CAC produces ATP – the gasoline with which most cells drive their particular activity ( ie: the peroxisomes inside each cell are responsible for most detoxification activities. For this they have a high need for ATP). Most toxins block individual steps of the CAC. Once the toxin is removed, the blockage often stays behind! Coenzyme comp often re-ignites the ATP production. Multiple body-systems start to function better soon after introduction of this remedy. Twice/week for 1st month, then once/week for entire treatment time. Change mode of application: im, s.c, i.c., intra-nasal, oral 73 Coenzyme compositum Amino acid Vitamins Catalysts of Krebs’s cycle Trace elements Homeop. remedies Other catalysts D10 D8 D6 Vit. C Vit. B6 Vit. B1 Vit. B2 Acidum Acidum Natrium citricumDL malicumoxalacet. α-lipon saeure ATP Nicotin- Acidum Acidum Natrium amid fumaricum succin. pyruv. Acidum Acidum Baryum Cystein cis-aconitum α-ketogl. oxalsucc. NAD Mg orotic Sulfur Cerium Pulsatilla oxalicum CoA Mn Hepar phosph. sulfuris 74 Dr. Dietrich Klinghardt 37 Treatment Protocol for ASD January 21, 2006 The Krebs/Citric Acid Cycle 75 – Step #4: clearing infections and infestations: use medical suggestions earlier in this paper. – Add these remedies: • Echinacea comp and Engystol: anti-viral defense system, also against staph and strep: give together for 6 weeks early in the parasite/infection control program and during viral infections (flu) in later stages of treatment. Best: 3 drops twice daily intranasally 76 Dr. Dietrich Klinghardt 38 0 Dr. Dietrich Klinghardt 20 10 6 Asclepias vincetoxicum 10 Asclepias vincetoxicum Asclepias vincetoxicum 5 Sulphur Sulphur 20 18 16 14 12 10 8 6 4 2 0 4 10 30 15 CPG Streptococcinum Staphylococcinum Influenzinum Cortisone Lachesis m utus Thuja occidentalis Pulsatilla Phytolaca decandra Gelsem ium serpervirens Euphorbium officinalis Euphatorium perfoliatum Bryonia alba Sanguinaria canadensis Rhus toxicodendrum Baptista tinctoria Arnica m ontana Echinacea angustifolia Aconitum napellus Hepar sulphur Zincum m etallicum Sulphur Phosphorus Mercurius corrosivus Arsenicum album Argentun nitricum Treatment Protocol for ASD January 21, 2006 Echinacea compositum IPG CPG PPG MPG 77 Engystol 30 25 MPG PPG CPG IPG MPG 78 39 Treatment Protocol for ASD January 21, 2006 – Step #5: Brain and System Repair: start after being on detox program at least for 4 months 79 Tonsilla compositum – Contains the homeopathic equivalent of stem cells and growth factors, adrenal and other healthy organ extracts and their RNA) – One amp/week. I-2 years. 80 Dr. Dietrich Klinghardt 40 Treatment Protocol for ASD January 21, 2006 Tonsilla compositum suis organ hormone nosode – – – – – – – – – – Acidicum ascorbium D6 Glandula lymphatica suis D8 Tonsilla suis D28 Medulla ossis suis D10 Funiculus umbicalis suis D10 Splen suis d10 Hypothalamus suis D10 Hepar suis D10 Embryo suis D13 Cortex glandulae suprarenalis suis D13 – Cortisonum aceticum D13(Catalyst) – Levothyroxinum D13 – – Pyrogenium nosode D 198 Psoriasis nosode D28 – – – – – – – Pulsatilla D6 , Conium D4 Galium Aparine D6, Aesculus D6 Echinacea Angustifolia D4 Tartarius stibatus D6 Dulcamara D4,Coccus Cacti D6 Gentiana Lutea D6 Geranium robertanium D6 – – – – – – Ferrum Phos phoricum d10 Calcium Phosphoricum d10 Merc. Sol Hahn. D13 Sulfur D8 Baryum Carbonicum D28 Acidicum Sarcolacticum D6 plant mineral 81 Ingredients Aesculus hippocastanum 4X Sarcolacticum acidum 4X Secale cornutum 4X Cuprum Sulphuricum 6X Melilotus 6X Placenta suis 6X Solanum nigrum 6X Strophanthus hispudus 6X Embryo totalis suis 8X Natrum pyruvicum 8X Vena suis 8X Arteria suis 10X Funiculus umbilicalis suis 10X Hypophysis suis 10X Tabacum 10X Vipera berus 10X Baryta carbonica 13X Plumbum iodatum 18X Characteristics Chilliness up and down back Tired feeling with muscular prostration, sore feeling all over Debility, anxiety, emaciation Cramp of plain and striped musculature Numb, aching knees, skin and extremities cold Peripheral circulatory disorders Violent restlessness, alternation of coldness and heat Generalized edema, swollen extremities Revitalization Promotes detoxification Varicose veins, crural ulcers Intermittent claudication Impairment of connective tissue Disorders of connective tissue function Legs and hands icy cold, limbs tremble Vericose veins, severe cramps in lower extremities Cold, clammy feet, icy coldness of body Muscular atrophy Placenta Comp: more growth factors from different sources. One amp/week 1-2 years 82 Dr. Dietrich Klinghardt 41 Treatment Protocol for ASD January 21, 2006 Other proven helpful remedies, which should be used only as needed: – Cerebrum Comp: should be tried once for 2 weeks. Continue only, if good effect – Nux vomica: try for abdominal distress – Valerianaheel: for ASD insomniacs and against brain herpes viruses – Apis Homaccord: to treat Borrelia infection and brain inflammation – Belladonna Homaccord: to reduce brain inflammation ( not suitable as long term remedy) 83 Ingredients Aesculus hippocastanum Cinchona officinalis Cocculus indicus Conium maculatum Gelsemium sempervirens Ruta graveolens Aconitum napellus Anacardium orientale Hyoscyamus niger Kali phosphoricum Thuja occidentalis Cerebrum suis Ignatia amara Kali bichromicum Manganum phosphoricum Ambra grisea Bothrops lanceolatus Embryo suis Hepar suis Magnesia phosphorica Phosphoricum acidum Placenta suis Selenium metallicum Sulphur Medorrhinum Arnica montana, radix Characteristics Head dullness and confusion Intense throbbing of head Profound sadness Disinterested; weak memory Dullness of mind Eye strain followed by headache Great fear; anxiety Impaired memory, absent-mindedness Deep stupor; confusion Confusion, irritability Memory deficiency Mental exhaustion, brain weakness Sad, uncommunicative Vertigo; frontal headache Weak memory, anemia Tearing pain in upper part of brain Speech and memory disorders Revitalization Stimulates hepatic function Inability to think clearly Apathetic, indifferent Peripheral circulation disturbances Mental labor fatigues; great debility Very forgetful, difficult thinking Weak memory, difficult concentration Indifferent, delirious 84 Dr. Dietrich Klinghardt 42 Treatment Protocol for ASD January 21, 2006 Nux vomica Homaccord D1000 D200 D30 D15 D10 D6 D3 D2 Nux Vomica Bryonia Lycopodium Colocynthis 85 Ingredients Valeriana officinalis 2X Picricum acidum 6X Prunus spinosa 2X Humulus lupulus 2X Hypericum perforatum 3X Melissa officinalis 2X Avena sativa 2X Chamomilla 2X Ammonium bromatum 2X Kali bromatum 2X Natrum bromatum 2X Characteristics over-sensitiveness; restlessness; insomnia heavy tired feeling; muscular debility; nervous exhaustion severe eye pain; anxious, short respiration day-time drowsiness; insomnia nerve injuries; melancholy nerve tonic; sedative nervous exhaustion; debility after illness whining restlessness; anxious, frightened dreams constrictive headache; nocturnal spasmodic cough extreme drowsiness; restless sleep sleeplessness; restlessness 86 Dr. Dietrich Klinghardt 43 Treatment Protocol for ASD January 21, 2006 Apis-Homaccord PPG MPG CPG IPG 1000 200 30 20 10 0 Antimonium tartaricum Scilla maritima Apisinum Apis mellifica 87 Belladonna-Homaccord 1000 PPG MPG CPG IPG 200 30 20 10 0 Belladonna Echinacea angustifolia 88 Dr. Dietrich Klinghardt 44 Treatment Protocol for ASD January 21, 2006 Clinical tips for parents Stool: – – – – – – Sesame seeds are worm eggs (ascaris) requires repeated courses of tx with Biltricide (take stool apart with stick from time to time to look for worm eggs) Apple seeds are tape worm eggs (treat with Albendazole). In boys: episodes of crazy behavior, often self destructive, is a sure sign of worm infestation (larvae often in brain). In girls: severe mood swings, if they are too tame and too easily steered, not enough own will (same cause) Light color: decreased bile flow and decreased detoxification via liver: increase Hepar comp or cilantro. Try dandelion with food (pick the older bitter leaves in your garden). Stop pushing detox agents that mainly use the liver as exit point (DMSA) Bloatedness is often a liver sign Diarrhea: often sign of overflow constipation (bypass phenomenon) try arsenicum album 30C from local health food store, Probiotics, change of food regime, Nux vomica (Heel) and Hepar comp, consider parasite regimen Chocolate pudding stool: enterocolitis (=infection) – check for measles, chlostridia, giardia and treat accordingly 89 Clinical tips for parents Urine: – Colorless urine: the kidneys are ‘plugged up”. Stop detox regime for a few days. Increase fluid intake and Berberis comp. Find practitioner who uses neural therapy (segmental treatment over kidney) – Monitor specific weight (buy strips from Walgreens): if on the heavy side, procede with detox, if on the light side: go slow – Low back pain and recurrent bladder infections are a sign that the program is working the kidneys too hard (not enough drainage support). Use D-mannose for recurrent infections (1 tsp q 4-6 h till resolved) 90 Dr. Dietrich Klinghardt 45 Treatment Protocol for ASD January 21, 2006 Clinical tips for parents – Odors: complete list in “DAN!2005 Physician’s Training Manual (619-281- 7165) page 8 91 Clinical tips for parents Magnesium deficiency (even if high dose is given) – list by Sid Baker MD – Muscle cramps and twitches (can also be copper deficiency! if Mag fails, try homeopathic cuprum met 12 X several times/day: you have used too much zinc and depleted the copper stores) – Constipation – Lump in throat – Sensitivity to loud noise and high pitched sounds – Cold hands and feet – Insomnia (try also homeopathic Valerian Heel) or Mag Phos 6 X at bedtime) – Carbohydrate cravings and intolerance (also chromium/vanadium – try herbal extract of gymnema) – Numbness and tingling – Cannot take deep breath 92 Dr. Dietrich Klinghardt 46 Treatment Protocol for ASD January 21, 2006 Clinical tips for parents Magnesium deficiency Generalized abdominal tenderness, palpable hardened small bowel loops: giardia (good stool test will show it, DiagnosTech in Seattle) – Treat with Tinidazole 250-500 mg bid for 10 days – Followed by 6 month course of freeze dried garlic 1-2 cap after each meal – Nux vomica-Homaccord (Heel) to detoxify drug residues 93 Clinical tips for parents Seizures: herpes virus (HSV-1, VZ or HHV-6) in brain inside Hg deposit: use finger acupressure (Y.Omura) to increase uptake of Hg detox meds and antivirals in affected area – Check for Electrosmog in sleeping glocation – Use high dose B-6 (see above) or medical drugs (Lamictal or Valproate) until underlying cause is resolved (usually about 1 year of detox) 94 Dr. Dietrich Klinghardt 47 Treatment Protocol for ASD January 21, 2006 Clinical tips for parents Child holding lower abdomen: pain Headaches: have experienced dentist or D.O. check the dental occlusion – Cilantro tea at bedtime ( 10 drops in hot water, BioPure) Recurrent ear infections/sinusitis: consider reflux at night (GERD). – Eat earlier and lighter for dinner – Heel Nux Vomica homaccord at bedtime – Cranio-sacral therapy (re-sets vagus nerve) – KMT lymphatic drainage Skin symptoms: family constellation (unresolved shame in family history, etc.) 95 96 Dr. Dietrich Klinghardt 48