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Universidad Nacional de Piura “Facultad de Medicina Humana” Título : "Factors Of Risk Prevalentes In The Rejection Of Cornea Transplante In The PERUVIAN INSTITUTE OF OPHTHALMOLOGY, PIURA 1997 - 2001". Autor : ROGER JAVIER VELÁSQUEZ SAAVEDRA. Tesis : Para Optar El Titulo De Medico Cirujano En La Facultad De Medicina Humana De La Universidad Nacional De Piura. Objetivo : Which Are The Factors Of Risk Prevail For The Rejection In The Cornea Transplante In The Peruvian Institute Of Ophthalmology - Piura, 1997 2001? Tipo De Estudio : RESUMEN: METHODOLOGY: it is a type of observational, retrospective, traverse study, to correlate and of cabinet. They were studied all the patients that presented rejection to the transplante of it horns during the years 1997 - 2001 that were in total 29 patients. Inclusion approaches operated:patient of cornea transplante in the IPO - Piura that presented rejection to the implant, from January of 1997 until December of the 2001, of both sexes, of all the ages intervened for the first time, to participate, and subjected to surgery of other structures of the eye. Exclusion approaches: patients operated in other hospitals, clinical of Piura or another city, patient operated outside of this time, patient that has not been subjected to this surgery, patient that doesn't perceive light (blindness), subjected to cornea autotransplante, patient with irreversible cerebral damage and infectious process of the previous segment. RESULTS: the time between the death and the extraction of the fabric corneal was of 7.17 hours, the time between the conservation and the surgery was of 6.6 days. the vascularización corneal was in 20 cases 54.05%, the state of the ocular annexes was normal, the defects epiteliales were of 11 cases (29.73%) the pressure intraocular you to give in 13 cases (35.14%), the retransplante was given in 8 cases (21.62%), we had 8 cases of surgery associated to the vitreous one, as complications post operative had 11 cases (29.73%), of effects persistent epiteliales and 15 cases (40.54%) of ocular hypertension, the period of rejection was in the first 6 months, and the donor's age influenced in the rejection, the pathology but it frequents it was the queratopatia bullosa (19 cases) that represents 51.35%, they were not carried out histocompatibilidad tests for not being made in the country. RECOMMENDATIONS: To carry out the tests of histocompatibilidad of the donating and receiving fabric, to begin a combined work to modify the population's idiosyncrasy, to qualify the personnel responsible for the extraction of the fabric corneal, treatment preoperatorio of the vascular corneal in the receiver, control preoperatorio and post operative of the ocular hypertension, to provision from appropriate material to the areas from where knitted corneal is obtained.