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Patrick J. Bolan Center for Magnetic Resonance Research 2021 6th Street SE, Minneapolis MN 55419 [email protected] 612/625-6526 Education 2003 1993 Ph.D. Biomedical Engineering, University of Minnesota, Minneapolis MN B.S. Mechanical Engineering, University of Illinois, Urbana IL Experience 2005 – Present 2003 – 2005 2000 – 2002 1997 – 1999 1994 – 1997 1993 – 1994 1989 – 1993 Assistant Professor Post-doctoral Associate Graduate Research Associate Sole Proprietor Associate Software Developer Graduate Research Associate Coop Student Center for Magnetic Resonance Research, Minneapolis MN Center for Magnetic Resonance Research, Minneapolis MN Center for Magnetic Resonance Research, Minneapolis MN Software development, database specialist The Premisys Corporation, Chicago IL Department of Nuclear Engineering, Berkeley CA Fermi National Accelerator Laboratory, Batavia IL Honors and Awards 2007 2006 2004 2003 2002 2002 2001 1999 1994 1993 RSNA Excellence in Design Award for Education Exhibit RSNA Research Scholar Masonic/Dietz Family Award for Educational Travel University of Minnesota Doctoral Dissertation Fellowship University of Minnesota Medical School Dean's Office Award Bill Negendank Award, ISMRM Cancer Workshop Best Poster, Design of Medical Devices Conference, University of Minnesota University of Minnesota Graduate School Fellowship National Science Foundation Graduate Fellowship University of California Regent's Fellowship Professional Societies International Society of Magnetic Resonance in Medicine, 2000-present Radiological Society of North America, 2005-present Reviewing Journals Grants 1/7 Magnetic Resonance in Medicine NMR in Biomedicine Journal of Magnetic Resonance Imaging IEEE Transactions in Medical Imaging MAGMA NIH CSR ZRG1 DTCS-A, Mail reviewer 2010 University of Minnesota Interdisciplinary Informatics Seed Grant, 2009 Singapore Biomedical Resource Council, 2008 Netherlands Organization for Scientific Research (NOW) Veni Grants, 2007 updated 10/18/2010 Peer-Reviewed Manuscripts 1. Bolan PJ, DelaBarre L, Baker EH, Merkle H, Everson LI, Yee D, Garwood M. Eliminating Spurious Sidebands in 1H MRS of Breast Lesions. Magn Reson Med 2002; 48:215-222 2. Bolan PJ, Meisamy S, Baker EH, Lin J, Emory T, Nelson M, Everson LI, Yee D, Garwood M. In vivo quantification of choline compounds in the breast with 1H MR spectroscopy. Magn Reson Med 2003; 50:11341143 3. Bolan PJ, Henry PG, Baker EH, Meisamy S, Garwood M. Measurement and correction of respiration-induced B0 variations in breast 1H MRS at 4 Tesla. Magn Reson Med 2004; 52:1239-1245 4. Meisamy S, Bolan PJ, Baker EH, Bliss RL, Gulbahce E, Everson LI, Nelson MT, Emory TH, Tuttle TM, Yee D, Garwood M. Neoadjuvant chemotherapy of locally advanced breast cancer: predicting response with in vivo 1H MR spectroscopy--a pilot study at 4 T. Radiology 2004; 233:424-431 5. Malgorzata M, Henry PG, Bolan PJ, Vaughan B, Seaquist ER, Gruetter R, Ugurbil K, Garwood M. Uncovering hidden in vivo resonances using editing based on localized TOCSY. Magn Reson Med 2005; 53:783-789 6. Bolan PJ, Nelson MT, Yee D, Garwood M. Imaging in Breast Cancer: Magnetic Resonance Spectroscopy. Breast Cancer Research 7:149-152 2005 7. Meisamy S, Bolan PJ, Baker EH, Pollema MG, Le CT, Kelcz F, Lechner MC, Luikens BA, Carlson RA, Brandt KR, Amrami KK, Nelson MT, Everson LI, Emory TH, Tuttle TM, Yee D, Garwood M. Adding in Vivo Quantitative 1H MR Spectroscopy to Improve Diagnostic Accuracy of Breast MR Imaging: Preliminary Results of Observer Performance Study at 4.0 T. Radiology 2005; 236(2):465-475 8. Bolan PJ, Yacoub E, Garwood M, Ugurbil K, Harel N. In vivo micro-MRI of intracortical neurovasculature. NeuroImage 2006, 32(1):62-9 9. Vaughan JT, DelaBarre L, Snyder C, Garwood M, Adriany G, Bolan PJ, Akgun C, Strupp J, Anderson P, Van de Moortele PF, Ugurbil K: RF Technology and Techniques for Highest Field MRI. In: Proceedings of IEEE Trans Biomed Eng, 2006 10. Nelson MT, Everson LI Garwood G, Emory T, Bolan PJ. Magnetic Resonance Spectroscopy in the Diagnosis and Treatment of Breast Cancer. Seminars in Breast Disease 2008; 11(2) 100-5 11. Haddadin I, McIntosh A, Meisamy S, Corum C, Styczynski-Snyder A, Powell N, Nelson M, Yee D, Garwood M, Bolan PJ. Metabolite Quantification and High-Field MRS in Breast Cancer. NMR in Biomedicine 2009; 22(1): 65-76 12. Vaughan JT, Snyder CJ, DelaBarre LJ, Bolan PJ, Tian J, Bolinger L, Adriany G, Anderson P, Strupp J, Ugurbil K. Whole-body Imaging at 7T: Preliminary Results. Magn Reson Med 2009; 61(1): 244-8 13. Corum CA, McIntosh AD, Bolan PJ, Nelson M, Snyder AL, Powell NJ, Boyum J, Emory TH, Yee D, Tuttle TM, Everson LI, Garwood M. Feasibility of Single-Voxel MRS Measurement of Apparent Diffusion Coefficient of Water in Breast Tumors. Magn Reson Med 2009, 61(5):1232-7 14. Harel N, Bolan PJ, Turner R, Ugurbil K, Yacoub E. Recent advances in high-resolution MR application and its implications for neurovascular coupling research. Frontiers in Neuroenergetics 2010, 1 (130): 1-8 Book Chapters 1. Garwood M, McIntosh A, Bolan PJ, Meisamy S, Snyder CJ, Stycznski A, DelaBarre L, Ellerman J, Gulbahce E, Tuttle T, Everson LI, Emory TH, Nelson MT, Yee D, Vaughan JT: Clinical Assessment of Breast Cancer using 1H MRS at High Magnetic Field. In Biomedical Magnetic Resonance: Proceedings of the International Workshop. Ed. Jagannathan NR. New Delhi: Jaypee, 2005. 412-422 Conference Abstracts 1. Merkle H, DelaBarre L, Bolan PJ, Baker EH, Everson LI, Yee D, Garwood M. Transceive Quadrature Breast Coils and Applications at 4 Tesla. In: Proceedings of the 9th Annual Meeting ISMRM, Glasgow, 2001 2. Bolan PJ, Baker E, DelaBarre L, Merkle H, Yee D, Everson LI, Garwood M. Effects of Gd-DTPA on breast 1H MRS at 4T. In: Proceedings of the 87th Annual Meeting RSNA, Chicago, 2001 3. DelaBarre L, Bolan PJ, Garwood M. Improving Dynamic Range in 3D MRI with RF Pulses Producing Quadratic Phase. In: Proceedings of the 9th Annual Meeting ISMRM, Glasgow, 2001 2/7 updated 10/18/2010 4. Baker EH, DelaBarre L, Bolan PJ, Merkle H, Yee D, Everson LI, Garwood M. Characterization of Benign and Malignant Breast Lesions Using 1H MRS at 4 Tesla. In: Proceedings of the 9th Annual Meeting ISMRM, Glasgow, 2001 5. Baker EH, Bolan PJ, DelaBarre L, Merkle H, Yee D, Everson LI, Garwood M. Monitoring Response to Neoadjuvant Chemotherapy for Locally Advanced Breast Cancer Using 4T 1H MRS. In: Proceedings of the 10th Annual Meeting ISMRM, Honolulu, 2002 6. Bolan PJ, Baker EH, Garwood M. Localization Schemes for Reducing Gradient-Induced Sidebands in MRS. In: Proceedings of the 10th Annual Meeting ISMRM, Honolulu, 2002 7. Bolan PJ, DelaBarre L, Baker EH, Merkle H, Everson LI, Yee D, Garwood M. Correcting Respiratory-Induced Frequency Shifts in Breast MRS at High Field. In: Proceedings of the 10th Annual Meeting ISMRM, Honolulu, 2002 8. Baker EH, Bolan PJ, DelaBarre L, Merkle H, Yee D, Everson LI, Ruter ST, Colford JW, Garwood M. Evaluation of Breast Abnormalities Using MRI and 1H MRS at 4T. In: Proceedings of the 102nd Annual ARRS, 2002 9. Bolan PJ, Baker EH, Meisamy S, Lin JC, Yee D, Garwood M. Quantification of Cho Levels in Breast Tissue using In Vivo MRS at 4T. In: Proceedings of the ISMRM Workshop on In Vivo Functional and Molecular Assessment of Cancer, 2002 10. Baker EH, Bolan PJ, Lin J, Sestero B, Everson L, Garwood M. Problems and Pitfalls in Magnetic Resonance Spectroscopy of the Breast. In: Proceedings of the 88th Annual Meeting RSNA, 2002 11. Meisamy S, Bolan PJ, Warren K, Gulbahce E, Baker EH, Lin JC, Nelson M, Yee D, Tuttle T, Garwood M. In Vivo Monitoring Response to Neoadjuvant Chemotherapy in Breast Cancer: A Quantitative Comparison between High Field MRI/MRS and Immunohistochemistry (Ki67). In: Proceedings of the 11th Annual Meeting ISMRM, Toronto, 2003 12. Bolan PJ, Baker EH, Meisamy S, Lin JC, Yee D, Garwood M. Quantification of In Vivo Breast MRS. In: Proceedings of the 11th Annual Meeting ISMRM, Toronto, 2003 13. Meisamy S, Bolan PJ, Everson L, Nelson M, Yee D, Garwood M, et al. Value of Adding MRS to MRI in Predicting Response to Neoadjuvant Chemotherapy of Locally Advanced Breast Cancer. In: Proceedings of the 89th Annual Meeting RSNA, Chicago, 2003 14. Meisamy S, Bolan PJ, Devine R, Chamberlain R, Kelcz F, Luikens B, Carlson R, Nelson MT, Everson LI, Emory T, Yee D, Garwood M. The Value of 1H MRS in Improving Clinical Assessment for the diagnosis of Breast Cancer: A Clinical Blind Study at 4 Tesla. In: Proceedings of the 12th Annual Meeting ISMRM, Kyoto, 2004 15. Lin J, Bolan PJ, Rickert B, De Larco J, Wuertz B, Sachdev D, Yee D, Garwood M. Detecting Early Tumor Response to Chemotherapy Using in vivo 1H MRS. In: Proceedings of the 12th Annual Meeting ISMRM, Kyoto, 2004 16. Bolan PJ, Aufferman WF, Henry P-G, Garwood M. Feasibility of Computer-Intensive Methods for Estimating the Variance of Spectral Fitting Parameters. In: Proceedings of the 12th Annual Meeting ISMRM, Kyoto, 2004 17. Meisamy S, Bolan PJ, Chamberlain R, Lin J, Nelson MT, Everson LI, Emory T, Yee D, Garwood M. The Effects of Breast Radiographic Markers on MRI and MRS: Ex Vivo Testing of Artifacts at High Magnetic Field (4 Tesla). In: Proceedings of the 12th Annual Meeting ISMRM, Kyoto, 2004 18. Marjanska M, Henry P-G, Bolan PJ, Gruetter R, Ugurbil K, Garwood M. Uncovering Hidden In Vivo Resonances Using 1D-TOCSY-LASER Spectroscopy. In: Proceedings of the 12th Annual Meeting ISMRM, Kyoto, 2004 19. Bolan PJ, Henry P-G, Baker EH, Meisamy S, Garwood M. Impact of Respiration-Induced B0 Variations on Quantitative 1H MRS of Breast Cancer at High Field. In: Proceedings of the ISMRM Workshop on Advances in Experimental and Clinical MR in Cancer Research, Manchester, 2004 20. Meisamy S, Nelson M, Bolan PJ, Emory T, Braun N, Garwood M. Development of New Soft Tissue Breast Radiographic Marker for Breast Biopsy and Other Soft Tissue Tumors. In: Proceedings of the 90th Annual Meeting RSNA, Chicago, 2004 21. Meisamy S, Bolan PJ, Nelson M, Everson L, Kelcz F, Garwood M, et al. The Value of Adding Quantitative 1H MRS for Improving Diagnostic Accuracy of Breast MRI: Results from an Observer Performance Study at High Field. In: Proceedings of the 90th Annual Meeting RSNA, Chicago, 2004 3/7 updated 10/18/2010 22. Marjanska M, Henry P-G, Bolan PJ, Gruetter R, Ugurbil K, Garwood M. Uncovering Hidden In Vivo Resonances Using 1D-TOCSY-LASER Spectroscopy. In: Proceedings of the 45th Annual Meeting ENC, Asilomar, 2004 23. Bolan PJ, Yacoub E, Garwood M, Harel N. In Vivo Micro-MRA of the Cat Intracortical Vasculature at 9.4T. In: Proceedings of the 13th Annual Meeting ISMRM, Miami, 2005 24. McIntosh A, Bolan PJ, Meisamy S, Styczynski A, Everson LI, Nelson MT, Emory T, Tuttle TM, Yee D, Garwood M. Using quantitative choline measurements to predict axillary node status in human breast cancer, in vivo. In: Proceedings of the13th Annual Meeting ISMRM, Miami 2005 25. McIntosh A, Bolan PJ, Meisamy S, Corum C, Styczynski A, Everson L, et al. Evaluation of 118 Women with Radiographic Breast Abnormalities Using High Field Quantitative 1H MRS and DCE MRI In Vivo. In: Proceedings of the 91st Annual Meeting RSNA, Chicago, 2005 26. Bolan PJ, Nelson M, Garwood M. A Novel Tissue Marker for Multimodal Breast Imaging. In: Proceedings of the 91st Annual Meeting RSNA, Chicago, 2005 27. Bolan PJ, Snyder CJ, DelaBarre LJ, Bolinger L, Garwood M, Vaughan JT. Preliminary Experience with Breast 1H MRS at 7 Tesla. In: Proceedings of the 14th Annual Meeting ISMRM, Seattle, 2006 28. Iltis IV, Bolan PJ, Merkle H, Snyder CJ, Corum CA, Ugurbil K, Garwood M, Henry PG. Localized 13C NMR Spectroscopy in the Human Breast In Vivo. In: Proceedings of the 14th Annual Meeting ISMRM, Seattle, 2006 29. Corum CA, McIntosh AD, Styczynski AL, Powell NJ, Kruse JR, Bolan PJ, Nelson M, Emory TH, Yee D, Tuttle TM, Everson LI, Garwood M. Breast Cancer Diagnosis Using Single-Voxel MRS Measurement of Apparent Diffusion Coefficient of Water. In: Proceedings of the 14th Annual Meeting ISMRM, Seattle, 2006 30. Moeller S, Prashanthi V, Snyder CJ, Delabarre LJ, Bolan PJ, Vaughan JT, Ugurbil K, Garwood M. Decoupling in Multi-Channel Bilateral Breast Imaging with Quadrature Coils. In: Proceedings of the 14th Annual Meeting ISMRM, Seattle, 2006 31. McIntosh AD, Corum C, Bolan PJ, Styczynski A, Powell N, Everson L, et al. A Quantitative Analysis of Water T2 Measurements in Benign and Malignant Breast Lesions In Vivo at 4 Tesla. In: Proceedings of the 92nd Annual Meeting RSNA, Chicago, 2006 32. Bolan PJ, Kolbe AB, Nelson MT. A Novel Soft Tissue Marker for Multimodal Breast Imaging with Positive MRI Contrast. In Proceedings of the 15th Annual Meeting ISMRM, Berlin 2007 33. Styczynski Snyder AL, Snyder CJ, Delabarre LJ, van de Moortele P-F, Vaughan JT, Ugurbil K, Garwood M, Bolan PJ. Preliminary Experience with Liver MRI and 1H MRS at 7 Tesla. In Proceedings of the 15th Annual Meeting ISMRM, Berlin 2007 34. Meisamy S, McIntosh A, Corum C, Styczynski Snyder AL, Bolan PJ, Garwood M, Haddadin IS, Powell N, Eberly L, Everson LI, Emory TH, Nelson M, Yee D, Tuttle T. Neoadjuvant Chemotherapy of Locally Advanced Breast Cancer: Predicting Response with Quantitative in Vivo 1H MR Spectroscopy at 4 Tesla in 31 Patients. In Proceedings of the 93rd Annual Meeting RSNA, Chicago 2007 35. Bolan PJ, Adriany G, Akgun C, Andersen P, Auerbach E, Delabarre L, Goerke U, Gozubuyuk A, Metzger G, Moeller S, Styczynski Snyder AL, Snyder CJ, Strupp J, Tian J, Van de Moortele P-F, Vaughan JT, Ugurbil K. Technical Aspects of Ultra-High Field (7 Telsa) Body MR Imaging and Spectroscopy. In Proceedings of the 93rd Annual Meeting RSNA, Chicago 2007 36. Goerke U, Bolan PJ, Akgun C, Adriany G, Snyder C, van de Moortele P-F, DelaBarre L, Harel N, Vaughan JT, Ugurbil K, Ellermann J. Ultrahigh Magnetic Field Imaging of the Knee Using a Transmit/Receive Array Coil. In Proceedings of the 16th Annual Meeting ISMRM, Toronto 2008 37. Snyder CJ, DelaBarre L, Metzger G, Akgun C, Bolan PJ, Ugurbil K, Vaughan JT. Separate Transmit and Receive Arrays for 7T Body Imaging. In Proceedings of the 16th Annual Meeting ISMRM, Toronto 2008 38. Akgun C, Snyder CJ, Moeller S, Bolan PJ, Vaughan JT, Ugurbil K, Van de Moortele P-F. Transmit and Receive FDTD Modeling as a Valuable Tool for RF Coil Development: Validation of Simulations with in Vivo Torso Imaging at 7 Tesla. In Proceedings of the 16th Annual Meeting ISMRM, Toronto 2008 39. Styczynski Snyder AL, Moeller S, Garwood M, Bolan PJ. Parallel Imaging in the Human Liver at 7 Tesla. In Proceedings of the 16th Annual Meeting ISMRM, Toronto 2008 4/7 updated 10/18/2010 40. Liimatainen T, Bolan PJ. Rapid B0 Shimming with Three Orthogonal Frequency Maps. In Proceedings of the 16th Annual Meeting ISMRM, Toronto 2008 41. Bolan PJ, Garwood, Rosen MA, Levering A, Blume JD, Gimpel J, Esserman LJ, Hylton N. Design of Quality Control Measures for a Multi-Site Clinical Trial of Breast MRS - ACRIN 6657. In Proceedings of the 16th Annual Meeting ISMRM, Toronto 2008 42. Metzger GJ, Weale P, DelaBarre LJ, Bolan PJ, Zuehlsdorff S, Nielles-Vallespin S, Van de Moortele P-F, Snyder CJ, Auerbach EJ, Vaughan JT, Ugurbil K, Jerecic R. Exploring the Promised Land of 7T for CMR with T-PAT Accelerated Imaging Techniques – First Results for Real Time Cardiac Function and Tagging in Volunteers. In Proceedings of the 12th Annual Meeting Soc Cardiovascular MR, Orlando FL 2009 43. Delabarre LJ, Weale P, Snyder CJ, van de Moortele P-F, Metzger GJ, Zuehlsdorff S, Nielles-Vallespin S, Bolan PJ, Auerbach E, Ugurbil K, Jerecic R, Vaughan JT. Cardiac Cine: Advances at 7T. In Proceedings of the 17th Annual Meeting ISMRM, Honolulu 2009 44. Brearley AM, Eberly LE, Mraz NR, Nelson MT, Yee D, Garwood M, Bolan PJ. Statistical Modeling of Longitudinal Total Choline Measurements during Chemotherapy. In Proceedings of the 17th Annual Meeting ISMRM, Honolulu 2009 45. Warmington LL, Adriany G, Snyder C, Auerbach EJ, Bolan PJ. 7T Breast Imaging with a 2-Channel Bilateral Loop Design. In Proceedings of the 17th Annual Meeting ISMRM, Honolulu 2009 46. Metzger GJ and Bolan PJ. Influence of Contrast-Dependent T2* Effects on DCE-MRI of the Prostate at 7T. In Proceedings of the 17th Annual Meeting ISMRM, Honolulu 2009 47. Zhao C, Bolan PJ, Sillerud L, Royce M, Wallace AM, Eberhardt S, Rosenberg R, Heintz P, Lomo L, Posse S. Proton-Echo-Planar-Spectroscopic-Imaging (PEPSI) in Human Breast. In Proceedings of the 17th Annual Meeting ISMRM, Honolulu 2009 48. Metzger GJ, Moeller S, Bolan PJ, Auerbach EJ, Park J-Y, Garwood M. Ultra Short Gradient Echo Imaging of the Prostate at 7T. In Proceedings of the 18th Annual Meeting ISMRM, Stockholm 2010 49. Zhao C, Bolan P, Royce M, Wallace A, Sillerud L, Eberhardt S, Rosenberg R, Lomo L, Posse S. A Total Choline Quantification Method for Water- and Lipid-Suppressed Breast Spectra at 3T. In Proceedings of the 18th Annual Meeting ISMRM, Stockholm 2010 50. Tkac I, Zacharoff L, Bolan PJ, Dubinsky JM. Longitudinal Changes in the Neurochemical Profile of Huntington R6/2 Mice. In Proceedings of the 18th Annual Meeting ISMRM, Stockholm 2010 51. Mraz NR, Nelson MT, Kuehn-Hajder J, Metzger G, Bolan PJ. Operator Performance of Voxel Placement for Single-Voxel MRS of Breast Lesions. In Proceedings of the 18th Annual Meeting ISMRM, Stockholm 2010 52. Bolan PJ, Baker EH, DelaBarre LJ, Merkle H, Yee D, Nelson MT, Everson L, Garwood M. The Impact of GdDTPA on Breast 1H MRS. In Proceedings of the 18th Annual Meeting ISMRM, Stockholm 2010 53. Carter JS, Rattigan D, Kuehn-Hajder JE, Lakkadi N, Iltis I, Downs Jr. L, Bolan PJ. Monitoring Treatment Response in Ovarian Cancer with Quantitative MR Methods: Preliminary Results. In Proceedings of the ISMRM Workshop on Improving Cancer Treatment with Advanced MR, Santa Cruz, CA, 2010 54. Bolan PJ, Carter JS, Rattigan D, Kuehn-Hajder JE, Lakkadi N, Iltis I, Downs Jr. L. Presurgical Characterization of Ovarian Masses with Quantitative MR Methods: Preliminary Results. In Proceedings of the ISMRM Workshop on Improving Cancer Treatment with Advanced MR, Santa Cruz, CA, 2010 55. Carter JS, Kuehn-Hajder JE, Lakkadi N, Iltis I, Downs Jr. L, Bolan PJ. Quantitative, Multi-Parametric Imaging at 3 Tesla to Monitor Treatment Response in Ovarian Cancer. In Proceedings of the 13th Biennial Meeting of the International Gynecological Cancer Society, Prague, 2010 56. Zhao C, Bolan P, Sillerud L, Royce M, Wallace A, Eberhardt S, Rosenberg R, Lee S-J, Lomo L, Posse S. Total Choline Measurement in Human Breast Using High-Speed MR Spectroscopic Imaging at 3T. In Proceedings of the 33rd Annual San Antonio Breast Cancer Symposium, San Antonio, TX, 2010 5/7 updated 10/18/2010 Invited Presentations 2010 University of Texas Southwestern Symposium on Intermediary Metabolism in Cancer: In Vivo MR Spectroscopy of Breast Cancer 2010 Cancer Research UK / Cambridge Research Institute Syposium: Monitoring Chemotherapy Response in Breast Cancer with Magnetic Resonance Spectroscopy 2009 Fifth International Conference on MR-Mammography, Jena, Germany: MRI/MRS of Breast Cancer: Why Do We Measure Total Choline and How Do We Do Breast Spectroscopy? 2008 RSNA, Chicago IL. Education course: Advances in Breast Imaging: Impact of PET MR Imaging and CT 2008 RSNA, Chicago IL. Scientific Focus Session: What is Diffusion-Weighted imaging and Can I do it on My Magnet? 2008 University of Cincinnati College of Medicine, Cincinnati OH. BITREC Seminar Series: MR Spectroscopy of Breast Cancer 2008 ACR 33rd National Conference on Breast Cancer, Orland FL. Educational Workshop: Technical Aspects of MR Imaging 2008 ACR 33rd National Conference on Breast Cancer, Orland FL. MR Spectroscopy and High Field Strength MR for the Breast 2008 ISMRM, Toronto ON. Clinical MRS Educational Course: Assessment of Breast Cancer with MRS 2008 University of New Mexico Cancer Center, Albuquerque NM. Clinical Research Seminar: Quantitative MR Spectroscopy of the Breast at High Field 2007 Minnesota Workshop on High Field MR Imaging and Spectroscopy & MRI of Brain Function, Minneapolis MN. Quantitative MR Spectroscopy of the Breast at High Field 2007 AMSE/UMN BME Design of Medical Devices Conference, Minneapolis MN. MR Imaging with Nanoparticle Contrast Agents 2006 ISMRM MR of Cancer Study Group Workshop: Frontiers in Metabolic, Molecular, and Clinical Imaging, Pocono Manor PA. MR Spectroscopy of the Breast 2006 ACRIN Think Tank on Novel Trial Designs in the Setting of Neoadjuvant Therapy for Breast Cancer. MR Spectroscopy as an In Vivo Biomarker 2006 New York Roentgen Society Annual Meeting, NY. Challenges and New Innovations in Breast Imaging: MRS 2006 Radiology Grand Rounds, New York Hospital-Weill Cornell Medical Center, NY. Quantitative in vivo MR Spectroscopy of Breast Cancer RSNA, Chicago IL. Breast Keynote Speaker, breast MR session. MR Spectroscopy of Breast Cancer: Methods and Applications 2005 2005 Breast MRI Educational Course, ISMRM, Miami FL. MR Spectroscopy of the Breast 2003 Minnesota Workshop on High Field MR Imaging and Spectroscopy & MRI of Brain Function, Minneapolis MN. Quantitative MRS of the Breast 1996 A/E/C Systems Conference, Los Angeles CA. Programming Languages in AutoCAD: ARX and ADS. Patents M. Garwood, K. Ugurbil, L. DelaBarre, P Bolan. Method and system for NMR using adiabatic RF pulses producing spatially quadratic phase. U.S. Patent No. 6,650,116 (2003) P. Bolan, M. Garwood. M. Nelson, D. Halpern. Tissue Marker for Multimodality Radiographic Imaging. U.S. Patent No. 7,702,378 (2010) 6/7 updated 10/18/2010 Research Support Pending Development of High-Field Magnetic Resonance Based Biomarkers for Ovarian Cancer NIH R01CA154576 (pending) Role: Co-Principal Investigator (Co-PIs: Bolan/Downs) Current Quantitative MRS of the Human Breast at 3T NIH R01 CA120509, 4/2007 – 11/2010 Role: Principal Investigator ACRIN Core PET Lab Physicist Agreement Subcontract from NIH CA80098, 1/2008 – 12/2010 Role: Principal investigator NMR Imaging and Localized Spectroscopy NIH P41 RR008079, 6/2008 – 5/2013 Role: Co-Principal Investigator, Core II, (PI: Ugurbil) Volumetric Mapping of Breast Cancer Biomarkers using High-Speed MR Spectroscopic Imaging NIH Challenge Grant RC1 EB010617-01, 2009-2010 Role: Consultant (PI: Posse) Correlation of Functional and Structural Units in Cerebral Cortex NIH R01 EB8008645, 9/2008 - 6/2012 Role: Co-investigator (PI: Harel) Past Breast MRI of Tumor Viability Komen Foundation, 5/2006 - 4/2008 Role: Co-investigator (PI: Todd Tuttle) Monitoring Chemotherapy Response in Metastatic Liver Cancer with Quantitative 1H MRS RSNA Research Scholar Grant, 7/2006- 6/2008 Role: Principal investigator Contrast Injectors for High Field MRI Studies Minnesota Medical Foundation Equipment Grant, 12/2007 - 11/2008 Role: Principal Investigator Uncovering the Spatial Origin of Tissue-fMRI Signals NIH R21 EB004460, 7/2006 – 6/2007 Role: Co-Investigator (PI: Harel) Coursework BPhys 8147 – Advanced Physics of MRI. (co-instructor, 2005) BPhys 8293 – Advanced Topics in Biomedical Magnetic Resonance Imaging and Spectroscopy. (co-instructor, 2006) EE 8860 – Seminar on Magnetics (guest lecturer, 2010) EE 8620 – Advanced Topics in Magnetics (guest lecturer, 2009) 7/7 updated 10/18/2010