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Get Up on Stage: The Role of Imaging in TNM Staging of Breast Cancer Back to Top LL-BRE2435 Geraldine H Chang , MD Julie Bykowski , MD Jade Quijano De Guzman , MD Hyung W Choi , BA Sarah L Blair , MD Haydee Ojeda-Fournier , MD PURPOSE/AIM 1. Discuss the radiologist role in breast cancer staging 2. Review the updated 7th ed. TNM system 3. Illustrate with multiple imaging modalities the clinical staging system 4. Self assessment using sample cases CONTENT ORGANIZATION Introduction; 7th Ed of Cancer Staging Manual; Principles and rules of staging; Clinical v. pathologic staging; Imaging modalities used to stage breast cancer; Tumor size; Multifocal and multi centric disease; Regional lymph node evaluation; Distant metastasis; Putting it all together; Sample cases in quiz format; Conclusion SUMMARY The staging of breast cancer has been developed and is maintained by the American Joint Committee on Cancer (AJCC). Patients are grouped according to extent of disease based on the tumor size, lymph nodes involved and metastasis using the TNM system. Staging is used to guide treatment, assign patients into clinical trials, and provide prognosis. The radiologist plays an important role in the clinical staging of breast cancer and is able to provide accurate primary tumor size, assessment of lymph nodes and presence or absence of distant metastasis.