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Last updated September, 2005
Rapid Response Radiotherapy Program
5-Year Summary
January 1999 – December 2004
Last updated September, 2005
Toronto Sunnybrook Regional Cancer Centre
Rapid Response Radiotherapy Program
5-Year Summary
Introduction
Rapid Response Radiotherapy Program (RRRP) at Toronto-Sunnybrook Regional Cancer Centre (TSRCC) has been
set up since 1996. Its mission is to deliver timely palliative radiotherapy to relieve symptoms in patients with
advanced cancer. Since then, the program has expanded to incorporate the Bone Metastases Clinic (BMC) jointly
run by orthopedic surgeons, radiation oncologists, palliative care physicians, interventional radiologists, nurses
and radiation therapist. It is the first of its kind in Canada providing multidisciplinary care to cancer patients with
bony metastases.
RRRP and BMC continue to expand and the membership currently includes:
Radiation Oncologists:
Lisa Barbera
Toni Barnes
Edward Chow (Bone Metastases Site Chair)
Cyril Danjoux (RRRP Chair)
Andrew Loblaw (spinal cord compression)
May Tsao
Orthopedic Surgeons:
Terry Axelrod
Joel Finkelstein
Michael Ford
Hans Kreder
David Stephen
Albert Yee (Bone Metastases Clinic Co-Chair)
Radiologists:
Richard Aviv
Monique Christakis
Joel Rubenstein
Linda Probyn
Robyn Pugash
Sean Symons
Radiation Therapist:
Emily Sinclair
Clinical Trials:
Mary O’Brien
Robin Norton-Tkalec
Medical Physicist:
Parminder Basran
Palliative Care Physicians:
Nina Horvath
Jeff Myers
Debbie Selby
Lesia Wynnychuk
Medical Oncologists:
Scott Berry
Mark Clemons
Yoo Ko
Maureen Trudeau
Pharmacists:
Trudi Schueller
Social Service:
Margaret Fitch
Magdeline Winterhoff
Laboratory Medicine:
David Cole
Reinhold Veith
Basic Science:
Gurmit Singh (Director of Research, Hamilton
Research Cancer Centre)
Shun Wong
Bioengineers:
Tomas Skrinskas
Cari Whyne
Nurses:
Grace Chan
Michelle Davis
Ernest Dixon
Cathy Doyle
Macey Farhadian
Rosemary Irish
Last updated September, 2005
T-SRCC Rapid Response Radiotherapy Program (RRRP)
The Rapid Response Radiotherapy Program was initiated in 1996. The Program consists of the Palliative
radiotherapy and bone metastases clinic. The Bone Metastases is recognized as a separate site group at TSRCC
under the leadership of Drs. Edward Chow and Dr. Joel Finkelstein and will not be included in the rest of this
report.
Palliative Radiotherapy Clinics
From the initial two clinics per week, the Palliative Radiotherapy clinics have increased to six half-day clinics per
week. In January 1999, the Radiation Oncologists involved with the program decided that the RRRP should not
only provide service but also be academically productive. Drs. Ewa Szumacher and Juhu Kamra are no longer
involved with the RRRP clinics. Dr. Toni Barnes has joined the RRRP program. Dr. Szumacher is pursing an MSc
in Education and will continue managing the monthly Palliative Care Rounds at TSRCC.
This report summarizes the academic activities of the RRRP.
Bone Metastases Clinic
A multidisciplinary Bone Metastases Clinic was started in January 1999 and is held on alternate Fridays. It is
staffed by the RRRP radiation oncologists, orthopedic surgeons, palliative care physician, nurses, and radiation
therapist. This year the Bone Metastases was recognized as a separate site group at the TSRCC under the
leadership of Drs. Edward Chow and Dr. Joel Finkelstein.
This report summarizes the academic activities of the RRRP.
Last updated September, 2005
EDUCATION
Monthly Palliative Care Rounds
CME Monthly Rounds:
The rounds are organized by Dr. E. Szumacher and held on the last Tuesday of the Month from 1-2
p.m. in the R.D.T. Jenkin Auditorium. They are accredited for MOCERT credits.
The subjects discussed during 2004 were:
Date
Title
Presenter(s)
January 27
"Palliative Radiotherapy in Bone and Brain Metastases – a Drs. Rebecca Wong and Andrea
research update from PMH”
Bezjak
February 24
"CANNABINOIDS - A NEW FRONTIER"
Dr. Vincent Maida
March 30
Preliminary results of a randomized study of accelerated
whole brain irradiation in patients with brain metastases
Dr. Phillip Davey
May 25
Information resources available to TSRCC STAFF
Ahtasham Rizvi
June 29
When Life Threatening Illness Strikes Our Loved Ones,
Our Children Grieve Too
Alva Murray, Jeanette Browne, Lisa
Brewitt, June Galbraith
September 28
An Overview on Art Therapy & Music Therapy
and Implications for Cancer Care
Susanne Watson-Bongard, Laurel
Young
The subjects discussed during 2003 were:
Date
Title
Presenter(s)
January 28
Palliative Care Emergencies (cases)
Drs. Andrew Loblaw, Cyril Danjoux,
Nina Horvath
February 25
New Research in Pain Management
Dr. Larry Librach
June 24
Palliative Care in the Elderly
Dr. Russell Goldman
September 30
Technology in Palliative Radiotherapy - which simulator
should we use?
Dr. Cyril Danjoux
October 28
Suffering and Healing in Palliative Care - the Patient,
Family and the and the Professional Caregiver
Mary Vachon and Nana Jokura
Last updated September, 2005
November 25
Issues in the Management of Patients with Brain
Metastases: Case-based discussions
Dr. May Tsao
The subjects discussed during 2002 were:
Date
Title
Presenter(s)
January 29
In search of the best palliative RT schedule for lung
cancer
Dr. Andrea Bezjak
March 26
Examining a novel neuroprotectant in malignant spinal
cord compression: human recombinany erythropoetin
Dr. Andrew Loblaw
April 30
Determination of the patient expectation of a clinically
relevant partial response as achieved with palliative
external beam radiotherapy for bone metastases
Dr. Edward Chow
May 28
Physicians’ expectation of palliative bone radiation –
where do we go from here?
Dr. Paula Wilson
October 22
Single Dose Pamidronate and External Beam
Radiotherapy for Painful Bone Metastases - Does it
work?”
Dr. Rebecca Wong
November 12
Quality of life in patients with brain metastases treated
with a palliative course of radiotherapy
Dr. May Tsao,
Ms. Grace Chan
Dr. Edward Chow
December 10
Is a trial of immediate vs. delayed radiotherapy for
asymptomatic brain metastases feasible?
Dr. Peiman Haddad
The subjects discussed during 2001 were:
Date
Title
Presenter(s)
January 30
Radiotherapy and Radiosurgery Treatment for Brain
Metastases
Dr. Philip Davey
February 27
Home Palliative Care
Dr. Russell Goldman
March 27
Treatment for the Breast – Metastatic Breast Cancer
Dr. Maureen Trudeau
April 24
Ethics in Palliative Care
Dr. Philip Hebert
May 29
Nutrition and Cancer
Ms. Pauline Wisdom
June 26
Role of Radiation Therapist in Palliative Radiotherapy
Ms. Ruth Connolly
Last updated September, 2005
September 25
Helping Others – Lending a Canadian Hand to a Most
Dedicated Physician: Outreach medical Clinic – Guyana,
South America
Toronto-Sunnybrook Regional Cancer Centre
Dr. Ewa Szumacher,
Dr. C. Booth, and
Ms. Kim Stefaniuk
October 30
Herbal Oncology: Science and Quack
Dr. Stanley Zheng
November 27
Update on Hormone Refractory Prostate Cancer
Dr. Scott Berry
The subjects discussed during 2000 were:
Date
Title
Presenter(s)
January 25
HDR Brachytherapy for Lung Cancer
Dr. Judith Balogh
February 29
Grief Management
Dr. Michelle Chaban
April 25
Care for the Dying Patient
Dr. Nina Horvath
May 30
Quality of Life as an End Point of Clinical Trials in
Oncology
Dr. Ian Tannock
June 27
Are Biosphonates An Effective Analgesia for Bone PainA Systemic review
Dr. Rebecca Wong
September 26
Research in Palliative Care – The Role of the
Biostatistician
Ms. Edmee Franssen
October 31
Bisphonates for Bone Metastases Update
Dr. Mark Vincent
November 28
From Hipprocrates To Hospice: A Historical Perspective
On Palliative Medicine
Dr. Charles Hayter
December 26
Cancelled – Christmas
The subjects discussed during 1999 were:
Date
Title
Presenter(s)
January 26
Metastatic disease to the spine.
Metastatic disease and pathological fracture of the
extremities.
Dr. J. Finkelstein
Dr. D. Stephen
February 23
Radiosurgery for brain metastases.
Dr. P. Davey
Last updated September, 2005
March 30
Pain and Symptom Management.
Dr. L. Librach
April 27
Single Dose Half Body Irradiation - 20 year Review.
Dr. C. Danjoux
May 25
Palliative Radiotherapy. An underused modality.
Dr. P. Kirkbride
June 29
Palliative Care Information Centre Metropolitan Toronto.
C .M. Freer
September 28
Adult learning and Patient Education.
B. Page
October 26
Evidence based Palliative Care.
Dr. A. Bezjak
November 30
Supportive Care for individuals living with cancer.
Dr. M. Fitch
.
Last updated September, 2005
Hot Spot
In response to a satisfaction survey from our referring physicians who wanted better communication, we initiated
a Quarterly Newsletter “HOT SPOT” in Feb 1999. The Newsletter is distributed to our referring physicians,
hospitals and other health Care workers. Requests for the newsletter has increased our circulation to over 1000.
The newsletter is also available on the TSRCC web site: http://www.tsrcc.on.ca/RRRP.htm. The February 2003
issue marked our 5th anniversary. We produced and mailed a special issue to all Ontario Family Physicians,
General Practitioners, and the regular list of readers.
The Editorial Board of Hot Spot consists of:
Editor:
Associate Editors:
Consultant:
Advisors:
Dr. C. Danjoux
Dr. E. Chow, Dr. R. Wong, and Ms. L. Andersson
Dr. S. Wong
Dr. T. Barnes, Dr. S. Berry, Dr. A. Bezjak, Dr. M. Fitch,
Dr. L. Librach, Ms. K. Stefaniuk, Dr. M. Tsao,
Dr. M. Vachon, Ms. M. Winterhoff, Ms. D. Adams
Editorial & Financial Manager: Mrs. M. Frost
The publication of the newsletter is made possible by the financial support of pharmaceutical & radiotherapy
equipment companies. Attached as Appendix E is a copy of the content of previous issues and inserts of Hot
Spot.
Last updated September, 2005
RESEARCH
1999-2004 Research
Grants
1. Integrin mediated mechanotransduction of cyclic hydrostatic pressure in intervertebral disc cells cultured in
vitro. North American Spine Society: Operating Grant ($50,000) 2001 – 2002 (PI – Dr. Yee)
2. Integrin mediated mechanotransduction of cyclic hydrostatic pressure in intervertebral disc cells cultured in
vitro. Sunnybrook Trust: Operating Grant. Sunnybrook & Women’s College Health Sciences Centre: Toronto,
Ontario ($25,000) 2001 – 2002 (PI – Dr. Yee)
3. Development of a metastatic femur model to study pressurization during prophylactic fixation. Dean’s Fund,
University of Toronto ($10,000) 2001-2002 (PI – Dr. Whyne)
4. Prediction of burst fracture risk in the metastatic thoracic spine with finite element analysis, NSERC Research
Grant ($96,000) 2001-2005 (PI – Dr. Whyne)
5. Integrin mediated mechanotransduction of cyclic hydrostatic pressure in rabbit intervertebral disc cells cultured
in vitro. Dean’s Fund, University of Toronto ($10,000) 2001-2002 (PI – Dr. Yee)
6. Integrin mediated mechanotransduction of cyclic hydrostatic pressure in rabbit intervertebral disc cells cultured
in vitro. Sunnybrook Trust ($25,000) 2001-2002 (PI – Dr. Yee)
7. Integrin mediated mechanotransduction of cyclic hydrostatic pressure in rabbit intervertebral disc cells cultured
in vitro. North American Spine Society ($50,000 US) 2001-2002 (PI – Dr. Yee)
8. Prevention of neurologic sequelae from malignant spinal cord compression: development and testing of a
tailored educational intervention and comprehension questionnaire. Aventis Pharmaceuticals, Inc ($10,000)
January 2002 (PI – Dr. Loblaw)
9. Assessment of the impact of a patient education intervention for patients living with bone metastases. TSRCC
Radiation Oncology Intramural funding ($4,120) March 2002 (Co-Investigator – Dr. Loblaw)
10. Malignant spinal cord compression: the Princess Margaret Hospital experience. Ortho-Biotech ($4,750) April
2002 (PI – Dr. Loblaw)
11. Recombinant human erythropoetin (r-HuEPO) in the prevention of neurologic sequelae from malignant spinal
cord compression: a proof of principle study. Ortho Biotech ($40,410 over 6 months) October 2002 (PI – Dr.
Loblaw)
12. Provision of quality of life information to physicians and nurses: Development & evaluation of touch screen
technology in palliative oncology practice. CIHR ($58,575 over 6 months) October 2002 (Co-Investigator – Dr.
Loblaw)
13. Evaluation of Remineralization Due to Radiotherapy for Breast Cancer Patients With Bony Metastases Using
Computerized Tomography (CT) Density Measurements - $15,565 (US). The Susan G. Komen Breast Cancer
Foundation. Chow E (PI), Danjoux C, Wong R, Szumacher E, Sixel K and Finkelstein J. 1999
14. A Prospective Assessment of Symptom Palliation for Patients Attending A Rapid Response Radiotherapy
Program and Bone Metastases Clinic - $10,000. Geoffrey H Wood Foundation Grant. Chow E (PI), Danjoux C,
Wong R, and Szumacher E. 2000
Last updated September, 2005
15. Validity and Utility of Biomechanically Determined Guidelines in Metastatic Burst Fracture Risk Assessment $38,000. Canadian Breast Cancer Foundation Ontario Chapter. Whyne C, Finkelstein J and Chow E (Coinvestigator). 2000
16. Determination of the Patient Expectation of a Clinically Relevant Partial Response as Achieved with Palliative
External Beam Radiotherapy for Bone Metastases - $10,000. University of Toronto Dean's Fund Competition for
New Staff Grants. Chow E (PI), Hruby G and Danjoux C. 2001
17. Prospective Validation of a Predictive Model for Survival in Metastatic Cancer Patients Attending an Outpatient
Palliative Radiotherapy Clinic - $8,000. Radiation Program Fund, Toronto-Sunnybrook Regional Cancer Centre.
Chow E (PI). 2002
18. Quality of life in patients with brain metastases treated with a palliative course of radiotherapy -$ 10,350.
Radiation Program Fund, Toronto-Sunnybrook Regional Cancer Centre. Tsao MN, Chow E (Co-investigator), and
Grace Chan. 2002
19. A Prospective Study of Biomechanically-Based Guidelines in Metastatic Burst Fracture Risk Prediction $330,000. Canadian Breast Cancer Research Initiative. 2003 – 2006. Whyne C (PI), Yee A, Kreder H, Finkelstein
J, Chow E (Co-investigator), Weller I, Barnes E, Clemons M and Trudeau M. 2003
20. A Clinical Trial to Reduce Acute Skin Toxicity for Breast Radiation Using Intensity Modulated Radiation
Therapy (IMRT) - $350,424. Canadian Institute of Health Research. 2003 – 2006. Pignol JP (PI), Benk V,
Rakovitch E, Paszat L, Bezjak A, Sixel K, Szumacher E, Tsao M, Chow E (Co-investigator) and Ackerman I. 2003
21. Validation of a predictive model for survival in metastatic cancer patients attending an outpatient palliative
radiotherapy clinic - $180,192. Canadian Institute of Health Research. 2004 – 2007. Chow E (PI), Panzarella T,
Bezjak A and Wu J. 2004
22. Development of a Canadian-led international bone metastases module to accompany European Organization
for Research and Treatment of Cancer Quality of Life Group core questionnaire (the EORTC QLQ-C30) for future
clinical trials in patients with bone metastases. - $271,483. National Cancer Institute of Canada. 2005-2008. Chow
E (PI), Clemons M, Wu J Bezjak A, Brundage M, Yee A, Bottomley A, Velikova G, and Hoskin P. 2005
23. Prospective quality of life study in patients with brain metastases. TSRCC intramural fund $10 000.
24. A phase II trial evaluating the benefit of zoledronic acid in breast cancer patients with progressive bone
metastases despite standard bisphosphonate therapy. Principal Investigator: M Clemons, Co-Investigators: S
Verma, M Trudeau. Granting Agency: Canadian Breast Cancer Foundation - Ontario Chapter. $93,000 over 1
year.
25. Evaluation of the palliative benefit due to ibandronate for breast cancer patients with progressive bone
metastases despite standard bisphosphonate therapy using pain scores, quality of life measures and biochemical
markers of bone turnover. Principal Investigator: M Clemons Co-Investigators: David Coles, George
Dranitsaris, Kathleen Pritchard, Sunil Verma, Maureen Trudeau Granting agency: Arms length grant-in-aid from
Roche ($160 000)
26. Should bisphosphonates be continued for life in patients with metastatic breast cancer?
Principal Investigator: M Clemons Granting Agency: Cancer Care Ontario, New Drug Funding Program ($5,000)
S&WCHSC Department of Medicine Student Summership Program Scholarship ($4,000)
Education in Bone Metastases Research
M. Clemons has recently compiled a McGill University CD-ROM Program in Oncology presentation on, Clinical Use
of Bisphosphonates in the Treatment of Skeletal Complications in Breast Cancer Patients with Bone Metastasis.
Last updated September, 2005
Carol Gillies R.T.T.,M.Sc.
Postgraduate Education:
2003
M.Sc. Radiography (Therapy)
Anglia Polytechnic University, Cambridge, U.K.
Thesis: An Integrated Clinic Model for the Multidisciplinary Management of Bone Metastases
Professional Recognition:
2004 A Multidisciplinary Collaborative Approach to the Management of Bone Metastases
Certificate of Merit, Percy Ghent Memorial Award exhibit competition, Ontario Association of
Medical Radiation Technologists
Publications
Peer Review
1. Chow E, Reardon DA, Shah AB, Jenkins JJ, Langston J, Heideman RL, Sanford RA, Kun LE, Merchant TE.
Pediatric Choroid Plexus Neoplasms. International Journal of Radiation Oncology, Biology and Physics
44(2): 249-254, 1999
2. Chow E, Danjoux CE, Pataki I, Franssen E, Jenkin RDT. Effect of Hemoglobin on Radiotherapy Response in
Paediatric Medulloblastoma. Should Children with a Low Haemoglobin be transfused for Radiation
Treatment? Medical and Pediatric Journal 32: 395-397, 1999
3. Chow E, Jenkins JJ, Burger PC, Reardon DA, Langston JW, Sanford RA, Heideman RL, Kun LE, Merchant TE.
Malignant Evolution of Choroid Plexus Papilloma. Pediatric Neurosurgery 31: 127-130, 1999
4. Andersson L, Chow E, Finkelstein J, Connolly R, Danjoux C, Szumacher E, Wong R, Stephen D, Axelrod T.
The Ultimate One-Stop for Cancer Patients with Bone Metastases: New Combined Bone Metastases Clinic.
Canadian Oncology Nursing Journal 9: 103-104, 1999
5. Chow E, Merchant TE, Pappo A, Jenkins JJ, Shah AB, Kun LE. Cutaneous and Subcutaneous Ewing’s
Sarcoma: An Indolent Disease. International Journal of Radiation Oncology, Biology and Physics 46(2):
433-438, 2000
6. Chow E, Wong R, Vachon M, Connolly R, Andersson L, Szumacher E, Franssen E, Danjoux C. Referring
Physicians’ Satisfaction with the Rapid Response Radiotherapy Program (RRRP), Toronto-Sunnybrook
Regional Cancer Centre (TSRCC) Survey Results. Supportive Care in Cancer 8: 405-409, 2000
7. Chow E, Danjoux C, Wong R, Szumacher E, Franssen E, Fung K, Finkelstein J, Andersson L, Connolly R.
Palliation of Bone Metastases: A Survey of Patterns of Practice among Canadian radiation oncologists.
Radiotherapy and Oncology 56: 305-314, 2000
8. Warde P, Gospodarowicz MK, Panzarella T, Chow E, Murphy T, Catton CN, Sturgeon JFG, Moore M, Milosevic
M, Jewett MAS. Long Term Outcome and Cost in the Management of Stage I Testicular Seminoma.
Canadian Journal of Urology 7: 967-972, 2000
9. Chow E, on behalf of the International Bone Metastases Consensus Working Party. International Bone
Metastases Consensus on Endpoint Measurements for Future Clinical Trials – Proceedings of the First Survey
and Meeting (work in progress). Clinical Oncology 13: 82-84, 2001
10. Chow E, Connolly R, Franssen E, Fung KW, Vachon M, Andersson L, Schueller T, Stefaniuk K, Szumacher E,
Hayter C, Pope J, Finkelstein J, Danjoux C. Prevalence of Underdosage of Cancer Bone Pain in Patients
Referred for Palliative Radiotherapy and its Potential Implications in Radiotherapy Trials. Annals The Royal
College of Physicians and Surgeons of Canada 34: 217-222, 2001 and 34: 290, 2001
11. Chow E, Andersson L, Wong R, Vachon M, Hruby G, Franssen E, Fung K, Harth T, Pach B, Pope J, Connolly J,
Schueller T, Stefaniuk K, Szumacher E, Hayter C, Finkelstein J and Danjoux C. Patients with Advanced
Cancer---A Survey of the Understanding of their Illness and Expectations from Palliative Radiotherapy for
Symptomatic Metastases. Clinical Oncology 13: 204 – 208, 2001
12. Chow E, Harth T, Hruby G, Finkelstein J, Wu J and Danjoux C. How Accurate are Physicians’ Clinical
Prediction of Survival and the Available Prognostic Tools in Estimating Survival Times in Terminally Ill Cancer
Patients? - A Systematic Review - Clinical Oncology 13: 209 – 218, 2001
Last updated September, 2005
13. Chow E, Connolly R, Wong R, Franssen E, Fung KW, Pach B, Vachon M, Andersson L, Schueller T, Stefaniuk
K, Szumacher E, Hayter C, Pope J, Finkelstein J, Danjoux C. Use of the CAGE Questionnaire for Screening
Problem Drinking in an Out-Patient Palliative Radiotherapy Clinic. Journal of Pain and Symptom Management
21: 491 – 497, 2001
14. Chow E, Wong R, Connolly R, Hruby G, Franssen E, Fung KW, Vachon M, Andersson L, Pope J, Holden L,
Szumacher E, Schueller T, Stefaniuk K, Finkelstein J, Hayter C, Danjoux C. Prospective Assessment of
Symptom Palliation for Patients Attending a Rapid Response Radiotherapy Program – Feasibility of Telephone
Follow-Up. Journal of Pain and Symptom Management 22(2): 649 – 656, 2001
15. Chow E, Wong R, Hruby G, Connolly R, Franssen E, Fung K, Andersson L, Schueller T, Stefaniuk K,
Szumacher E, Hayter C, Pope J, Finkelstein J and Danjoux C. Prospective Patient-Based Assessment of
Effectiveness of Palliative Radiotherapy for Bone Metastases in an Out-Patient Radiotherapy Clinic.
Radiotherapy and Oncology 61: 77 – 82, 2001
16. Szumacher E, Wighton A, Franssen E, Chow E, Tsao M, Ackerman E, Andersson L, Kim J, Wojcicka A, Ung Y,
Sixel K, Hayter C. Phase II Study Assessing the Effectiveness of Biafine Cream as a Prophylactic Agent for
Radiation Induced Acute Skin Toxicity to the Breast in Women Undergoing Radiotherapy with Concomitant
CMF Chemotherapy. International Journal of Radiation Oncology, Biology and Physics 51: 81 – 86, 2001
17. Wu J, Bezjak A, Chow E, Kirkbride P. Treatment Endpoints following Palliative Radiotherapy for Painful Bone
Metastases: Need for a Consensus Definition? Clinical Oncology 14: 70 – 77, 2002
18. Chow E. Radiation treatment for breast cancer. Canadian Family Physician 48: 1065-1069, 2002
19. Chow E, Fung KW, Panzarella T, Bezjak A, Danjoux C, Tannock I. A predictive model for survival in
metastatic cancer patients attending an out-patient palliative radiotherapy clinic. International Journal of
Radiation Oncology, Biology and Physics 53(5): 1291-1302, 2002
20. Chow E, Payne D, O’Sullivan B, Pintilie M, Liu F, Waldron J, Warde P, Cummings B. Radiotherapy alone in
Patients with Advanced Nasopharyngeal Cancer: Comparison with an Intergroup Study. Is Combined
Modality Treatment Really Necessary? Radiotherapy and Oncology 63: 269-274, 2002
21. Wong R, Franssen E, Szumacher E, Connolly R, Evans M, Page B, Chow E, Hayter C, Harth T, Andersson L,
Pope J, Danjoux C. What do patients living with advanced cancer and their carers want to know? - A needs
assessment. Supportive Care in Cancer 10: 408-415, 2002
22. Chow E, Wu J, Hoskin P, Coia L, Bentzen S, Blitzer P on behalf of the International Bone Metastases
Consensus Working Party. International consensus on palliative radiotherapy endpoints for future clinical
trials in bone metastases. Radiotherapy and Oncology 64: 275-280, 2002
23. Wai, EK, Finkelstein JA, Tangente RP, Holden L, Chow E, Ford M, Yee A. Quality of Life in Surgical Treatment
of Metastatic Spine Disease. Spine 28(5): 508-512, 2003
24. Szumacher E, Franssen E, Hayter C, Chow E, Andersson L, Wong R, Loblaw A, Danjoux C. Multidisciplinary
Radiation Oncology Palliative Care Rounds as a Continuing Educational Activity Implementing the Rapid
Response Radiotherapy Program at the Toronto Sunnybrook Regional Cancer Centre. Journal of Cancer
Education 18(2): 86-90, 2003
25. Finkelstein J, Zaveri G, Wai E, Vidmar M, Kreder H, Chow E. A population-based study of surgery for spinal
metastases. Journal of Bone & Joint Surgery (Br) 85(7) : 1045-1050, 2003
26. Finlay M, Sherman C, Rubenstein J, Wierzbicki R, Chow E. A late relapse of primary Krukenberg tumor with
bone metastases: a case report. Clinical Oncology 15(8): 500-503, 2003
27. Wu J, Bezjak A, Chow E, Cross P, Genest P, Grant N, Kirkbride P, Roy I, Whelan T, Fitzgibbon E, Wong R. A
consensus development approach to define national research priorities in bone metastases - Proceedings
from NCIC CTG workshop. Clinical Oncology 15: 496-499, 2003
28. Rakovitch E, Tsao M, Ung Y, Pignol JP, Cheung P, Chow E. Comparison of the efficacy and acute toxicity of
weekly versus daily chemoradiotherapy for non-small-cell lung cancer: a meta-analysis International Journal
of Radiation Oncology, Biology and Physics 58(1): 196-203, 2004
29. Enright K, Clemons M, Chow E. Utilization of palliative radiotherapy for breast cancer patients with bone
metastases treated with bisphosphonates – Toronto Sunnybrook Regional Cancer Centre experience.
Supportive Care in Cancer 12(1): 48-52, 2004
30. Chow E, Tsao M, Harth T. Does psychosocial intervention improve survival in cancer? A meta-analysis.
Palliative Medicine 18: 25-31, 2004
31. Barnes E, DeBoer G, Chow E. Symptom control and palliative care content of abstracts presented at the
Canadian Association of Radiation Oncologists Annual Meeting. Supportive Care in Cancer 12(2): 91-94, 2004
32. Roth SE, Mousavi P, Finkelstein J, Chow E, Whyne CM. Metastatic burst fracture risk prediction using
biomechanically based equations. Clinical Orthopedics and Related Research 419: 83-90, 2004
Last updated September, 2005
33. Chow E, Holden L, Danjoux C, Vidmar M, Connolly R, Finkelstein J, Cheung G. Successful salvage using
percutaneous vertebroplasty in cancer patients with painful spinal metastases or osteoporotic compression
fractures. Radiotherapy and Oncology 70 (3): 265-267, 2004
34. Chow E, Holden L, Rubenstein J, Christakis M, Sixel K, Vidmar M, Finkelstein J, Hayter C, Loblaw A, Wong R,
Szumacher E, Danjoux C. Computed tomography (CT) evaluation of breast cancer patients with osteolytic
bone metastases undergoing palliative radiotherapy – A feasibility study. Radiotherapy and Oncology 70 (3):
291-294, 2004
35. Chow E, Davis L, Holden L, Schueller T, Wong R, Hayter C, Hruby G, Fung KW, Szumacher E, Loblaw A,
Danjoux C. A comparison of radiotherapy outcomes of bone metastases employing international consensus
endpoints and traditional endpoints. Supportive Cancer Therapy 1(3): 173-178, 2004
36. Chow E, Hruby G, Davis L, Holden L, Fung KW, Schueller, Wong R, Hayter C, Szumacher E, Loblaw A,
Danjoux C. Quality of life after local external beam radiotherapy for symptomatic bone metastases - a
prospective evaluation. Supportive Cancer Therapy 1(3): 179-184, 2004
37. Clemons M, Enright K, Cesta A, Charbonneau F, Chow E, Warr D, Kerr-Cresswell D, Chang J, Yogendran G,
Trudeau M, De Angelis C, Cottrell W, Dranitsaris G. Do physicians follow systemic treatment and funding
policy guidelines? A review of bisphosphonate use in patients with bone metastases from breast cancer.
Canadian Journal of Clinical Pharmacology. 11(1): e168-e178, 2004
38. Lock M, Chow E, Pond G, Do V, Danjoux C, Dinniwell D, Lea J, Bezjak A. Prognostic factors in brain
metastases: can we determine patients who do not benefit from whole brain radiotherapy? Clinical Oncology
16: 332-338, 2004
39. Barnes E, Chow E, Andersson L, Hayter C, Loblaw A, Lee D, Holden L, Chan G, Danjoux C. Communication
with referring physicians in a palliative radiotherapy clinic.
Supportive Care in Cancer 12: 669-673, 2004
40. Lutz S, Spence C, Chow E, Janjan N, Connor S. Survey on utilization of palliative radiotherapy in hospice
care. Journal of Clinical Oncology 22(17); 3581-3586, 2004
41. Chow E, Davis L, Panzarella T, Hayter C, Szumacher E, Loblaw A, Wong R, Danjoux C. Accuracy of survival
prediction by palliative radiation oncologists. International Journal of Radiation Oncology, Biology and Physics
61(3); 870-873, 2005
42. Chow E, Fung K, Bradley N, Davis L, Holden L, Danjoux C. Review of telephone follow-up experience at Rapid
Response Radiotherapy Program. Supportive Care in Cancer. (published on line Nov 5, 2004)
51. de Borja M, Chow E, Bovett G, Davis L, Gilles C. The correlation among patients and health
care professionals in assessing functional status using the Karnofsky and Eastern Cooperative
Oncology Group performance status scales. Supportive Cancer Therapy 2(1); 59-63, 2004
52. Chow E, Ling A, Davis L, Panzarella T, Danjoux C. Pain flare following external beam
radiotherapy and meaningful change in pain scores in the treatment of bone metastases.
Radiotherapy and Oncology 75; 64-69, 2005
53. Lee J, Holden L, Fung K, Danjoux, Chow E, Gillies C. Impact of severe acute respiratory
syndrome on patient access to palliative radiation therapy. Supportive Cancer Therapy 2(2); 109-113, 2005
54. Szumacher E, Wong R, Franssen E, Thomas HL, Chow E, Danjoux C, Hayter C, Andersson L. Patient
participation in decision making process involving palliative radiotherapy treatment for bone metastases.
International Journal of Radiation Oncology, Biology and Physics 61 (5); 1473-1481, 2005
55. Greig M, Chow E, Bovett G, Abdolell M, Gillies C. Level of concordance between proxy
and cancer patient’s ratings in brief pain inventory. Supportive Cancer Therapy ( in press)
56. Chow E, Davis L, Holden L, Tsao M, Danjoux C. Prospective assessment of patient rated
symptoms following whole brain radiotherapy for brain metastases. Journal of Pain and
Symptom Management 30(1); 18-23, 2005
57. Bradley N, Davis L, Chow E. Symptom distress in patients attending an outpatient
palliative radiotherapy clinic. Journal of Pain and Symptom Management 30(2); 123-133,
2005
58. Tsao M, Lloyd N, Wong R, Rakovitch E, Chow E, Laperriere N and the Supportive Care Guidelines Group of
Cancer Care Ontario’s Program in Evidence-based Care. Radiotherapeutic management of brain metastases:
a systematic review and meta-analysis. Cancer Treatment Reviews 31; 256-273, 2005
59. Danjoux C, Chow E, Hayter C, Tsao M, Barnes E, Holden L, Sinclair E, Drossos A,
Farhadian M. An innovative Rapid Response Radiotherapy Program to reduce waiting time
for palliative radiotherapy. Supportive Care in Cancer (published on line April 2005)
60. Mackillop WJ, Zhou S, Groome PA, Dixon P, Cummings BJ, Hayter C, Paszat L. Changes in the Use of
Last updated September, 2005
Radiotherapy in Ontario: 1984-1995. Int J Rad Oncol Biol Phys, 44(2):355-362, 1999.
61. Hayter C, Huff-Winters C, Paszat L, Youssef, Y, Shelley WE, Schulze K. A Prospective Trial of Short-Course
Radiotherapy plus Chemotherapy for Palliation of Dysphagia from Advanced Esophageal Cancer.
Radiotherapy and Oncology 56: 329-333, 2000.
62. Tsao MN, Sultanem K, Chiu D, Copps F, Dixon P, Easton D, Haddad P, Hayter C, Hoegler D, Wong R; National
Cancer Institute of Canada Workshop on Symptom Control in Radiation Oncology. Supportive care
management of brain metastases: what is known and what we need to know. Conference proceedings of the
National Cancer Institute of Canada (NCIC) Workshop on Symptom Control in Radiation Oncology. Clin Oncol
(R Coll Radiol). 2003 Oct;15(7):429-34.
63. Grunfeld E, Zitzelsberger L, Evans WK, Cameron R, Hayter C, Berman N, Stern H. Better knowledge translation
for effective cancer control: a priority for action. Cancer Causes and Control 2004: 15 (5): 503-10.
64. Grunfeld E, Zitzelsberger L, Hayter C, Berman N, Cameron R, Evans WK, Stern H.The role of knowledge
translation for cancer control in Canada. Chronic Dis Can. 2004 Spring;25(2):57-62.
65. Finkelstein, Joel A, Gillies, Carol, The Bone Metastases Clinic: A Multidimensional management approach,
Oncology Exchange, Vol. 2, No. 1, February 2003 Reprinted with permission in The Canadian Journal of
Medical Radiation Technologists, Vol. 35, No. 2, Summer 2004
66. Gainford MC, Dranitsaris G, Clemons M. Systemic Treatment Of Bone Metastases From Breast Cancer - All That
It Is Cracked Up To Be? Jornal of Clinical Oncology - letter (in press)
67. Gainford MC, Chow E, Cole DEC, Shim K, Clemons M. Systemic Treatment Of Bone Metastases From Breast
Cancer - All That It’s Cracked Up To Be? Innovations in Breast Cancer Management (in press)
68. Clemons M, Verma S. Should oral bisphosphonates be standard of care in women with early breast cancer?
Breast Cancer Research and Treatment 2005;90(3):315-8
69. Gainford MC, Dranitsaris G, Clemons M. Recent developments in bisphosphonates for patients with metastatic
breast cancer. British Medical Journal 2005 Apr 2;330(7494):769-73
70. Clemons M, Rea D. Perspectives on the future of bisphosphonate use in breast cancer patients. Seminars in
Oncology 2004; 31(5 Suppl 10): 87-91
71. Clamp A, Danson S, Nguyen H, Cole D, Clemons M. Assessment of therapeutic response in patients with
metastatic bone disease. Lancet Oncology 2004 5:607-16.
72. Verma S, Kerr-Cresswell D, Dranitsaris G, Charbonneau F, Trudeau F, Yogendran G, Cesta A-M, Clemons M.
Bisphosphonate use for the management of breast cancer patients with bone metastases: A survey of
Canadian Medical Oncologists. Supportive Care in Cancer 2004 Dec; 12(12):852-8. Epub 2004 Aug 21 Senior Principal Author.
73. Clemons M, Enright K, Cesta A, Charbonneau F, Chow E, Warr D, Kerr-Cresswell D, Chang J, Yogendran G,
Trudeau M, De Angelis C, Cottrell W, Dranitsaris G. Do physician follow systemic treatment and funding policy
guidelines? A review of bisphosphonate use in patients with bone metastases from breast cancer. The
Canadian Journal of Clinical Pharmacology 2004 Spring; 11(1): e168-78 (www.cjcp.ca <http://www.cjcp.ca>)
- Senior Principal Author.
74. Clemons M. Should All Breast Cancer Patients with Symptomatic Bone Metastases be Treated with
Bisphosphonates? Clinical Oncology (R Coll Radiol). 2004: 16(2): 108-111 - Senior Principal Author.
75. Roth SE, Rebello MM, Kreder HJ, Whyne CM. Pressurization of the Metastatic Femur During Prophylactic
Intramedullary Nail Fixation, J Trauma 2004 Aug;57(2):333-9.
76. Tschirhart C., Nagpurkar A., Whyne C. Effects of tumor location, shape and surface texture on metastatic burst
fracture risk using finite element analysis. Journal of Biomechanics 2004 May;37(5):653-60.
77. Roth SE, Mousavi P, Finkelstein J, Chow E, Kreder H, Whyne CM, Metastatic Burst Fracture Risk Prediction
Using Biomechanically Based Equations. Clin Orthop 2004 Feb;(419):83-90.
78. Reidy D, Ahn H, Mousavi P, Finkelstein J, Whyne CM, A Biomechanical Analysis of Intravertebral Pressures
During Vertebroplasty of Cadaveric Spines With and Without Simulated Metastases. Spine 2003 Jul
15;28(14):1534-9.
79. Mousavi P, Roth SE, Finkelstein J, Cheung G, Whyne C, Volumetric Quantification of Cement Leakage
Following Percutaneous Vertebroplasty in Metastatic and Osteoporotic Vertebrae. J. Neurosurg (Spine1) 2003
Jul;99(1 Suppl):56-9.
80. Whyne, CM., Hu, S., Lotz, J., Biomechanically derived guideline equations for burst fracture risk prediction in
the metastatically involved spine. J Spinal Disord Tech. 2003 Apr;16(2):180-5.
81. Whyne, CM., Hu, S., Lotz, J. Burst fracture in the metastatically involved spine. Development, validation, and
parametric analysis of a three-dimensional poroelastic finite element model. Spine 2003 Apr 1;28(7):652-60.
Last updated September, 2005
82. Whyne CM., Hu SS., Lotz JC. Parametric finite element analysis of vertebral bodies affected by tumors. J
Biomech. 2001 Oct;34(10):1317-24.
Accepted or In Press Refereed Papers (acceptance letters/proofs attached)
1. Burch S, Bisland SK, Bogaards A, Wilson B, Whyne C, Finkelstein J, Yee AJ: Photodynamic therapy for the
treatment of spinal metastases. Journal of Orthopaedic Research
2. Tschirhart C., Roth S., Whyne C. Biomechanical assessment of stability in the metastatic spine following
percutaneous vertebroplasty: Effects of cement distribution patterns and volume. Journal of Biomechanics
Submitted Refereed Papers
1. Burch S, Bisland S, Bogaards A, Whyne C, Yang B, Finkelstein J, Wilson B, Yee A Evaluation of vertebral
metastases in a preclinical rat model of breast carcinoma. Spine
2. Ahn H, Mousavi P, Roth S, Reidy D, Finkelstein J, Vitkin A, Whyne C Stability Of The Metastatic Spine, Pre
And Post Vertebroplasty. Journal of Spinal Dirsorders and Techniques
3. Ahn H, Mousavi P, Chin L, Roth S, Finkelstein J, Vitkin A, Whyne C. The effect of pre-vertebroplasty
tumor ablation using laser induced thermo-therapy on biomechanical stability and cement fill in the
metastatic spine. Spine
83.
Non Peer Review
1. Chow E, Danjoux C, and Andersson L. Superior Vena Cava Syndrome. Patient Care Canada 10: 5760, 1999
2. Chow E, Danjoux C. A Need for Mentoring in Academic Radiation Oncology. Current Oncology 6:
103-105, 1999
3. Danjoux C, Chow E. Creating a Supportive Mentoring Environment for Academic Radiation Oncology.
Current Oncology 6: 106-107, 1999
4. Chow E, Finkelstein J, Connolly R, Andersson L, Pope J, Axelrod T, Stephen D, Szumacher E, Wong R,
Hayter C, Danjoux C. New combined bone metastases clinic: The ultimate one-stop for cancer
patients with bone metastases. Current Oncology 7: 205-208, 2000
5. Chow E, Finkelstein J, and Cheung G. Pain relief and fracture prevention in bone cancer and
osteoporotic patients with percutaneous vertebroplasty/ cementoplasty. Hospital News 13(8): 15,
2000
6. Chow E. Bone metastases: what is known and what is not known. Hospital News 13(8): 18, 2000
7. Chow E and Finkelstein J. New bone metastases clinic: the ultimate one stop for cancer patients with
bone metastases. Hospital News 13(8): 15, 2000
8. Danjoux C and Chow E. Palliative Radiotherapy Program, Rapid Response Radiotherapy Program and
Bone Metastases Clinic. Oncology Exchange 3(3): 8, 2000
9. Danjoux C, Szumacher E, Andersson L, Franssen E, Wong R, Chow E, Connolly R, Pope J, Hayter C.R,
Finkelstein J, Axelrod T, Stephan D, Sixel K, Thomas G, Schueller T, Stefaniuk K. Palliative
radiotherapy at Toronto-Sunnybrook Regional Cancer Centre. Current Oncology 7: 52-56, 2000
10. Chow E. An unexpected finding. Dealing with breast cancer in pregnancy. Parkhurst Exchange 9(7):
38-39, 2001
11. Lock M, Chow E. Survival prediction: Doctor how long do I have to live? Patient Care Canada 12: 46
– 48, 2001
12. Chow E, Bolderston A. The ins and outs of radiation. In Stride Winter 4 – 6, 2002
13. Chow E. What's involved in cancer clinical trials? In Stride Winter 8 , 2002
14. Chow E, Coia L, Wu J, Janjan N, Kirkbride P, Hoskin P, Blitzer P. This house believes that multiplefraction radiotherapy is a barrier to referral for palliative radiotherapy for bone metastases. Current
Oncology 9(3): 60-66, 2002
15. Wu J, Chow E. Survival of patients with bone metastases enrolled in randomized trials of palliative
radiotherapy. Current Oncology 9(3): 67-71, 2002
16. Ling A, Rubenstein J, Christakis M, Kreder M, Koren S, Chow E. Multiple stress fractures due to
osteopenia (likely from osteoporosis). Case reports from the University of Toronto Faculty of
Medicine. University of Toronto Medicine Journal 80(1): 45 and 48, 2002
17. Chow E, Holden L, Fung KW, Turner A, Andersson L, Pope J, Danjoux C. Edmonton Symptom
Assessment System scopes in metastatic cancer patients referred for palliative radiotherapy: a
comparison with scores in healthy individuals. Current Oncology 10(2): 133-137, 2003
18. Danjoux C, Franssen E, Chow E, Wong R, Connolly R, Andersson L, Holden L, Stefaniuk K, Schueller
T, Librach L, Pope J, Szumacher E, Hayter C. Sublingual fentanyl citrate for control of breakthrough
pain in patients referred for palliative radiotherapy. Current Oncology 11(1): 3-7, 2004
19. Chow E. Should I participate in clinical trials? In Stride Spring 8 , 2004
20. Li K, Fung K, Sinclair E, Danjoux C, Barnes E, Tsao M, Chow E. Correlation of pain scores
with functional interference in the Brief Pain Inventory. Current Oncology 12(2): 37-43,
2005
21. Hayter, C. R. The beginning of palliative radiotherapy in Canada. Hot Spot; 2:1, February 2000.
22. Hayter, C. R. Dr. Joseph-Ernest Gendreau and the early use of radium. Hot Spot; 2:2, May 2000.
23. Hayter, C. R. Private radiotherapy in Canada. Hot Spot; 2:3, August 2000
24. Hayter, C. R. Vera Peters: Canadian poineer in psychosocial oncology. Hot Spot; 2:4, November
2000.
25. Hayter, C. R. Cancer care before medicare. Hot Spot; 3:1, February 2001.
26. Hayter, C. R. The history of hospices. Hot Spot; 3:2, May 2001.
27. Hayter, C. R. The history of morphine. Hot Spot; 3:3, August 2001.
28. Hayter, C. R. The 50th anniversary of colbalt treatment. Hot Spot; 3:4, November 2001.
29. Hayter, C. R. The story of Essiac. Hot Spot; 4:1, February 2002.
30. Hayter, C. R. Blood and medicine. Hot Spot; 4:2, May 2002.
31. Hayter, C. R. Plants, poisons and potions: Drug treatments for cancer. Hot Spot; 4:3, August 2002.
32. Hayter, C.R. Charles Huggins; Canadian pioneer in hormone therapy. Hot Spot; 4:4, November 2002.
33. Hayter, C.R. A Century of Radiation Therapy In Canada Hot Spot; 5:1, February 2003.
34. Hayter, C.R. Spring fever. Hot Spot 5:2, May 2003.
35. Hayter, C.R. The History of Oxygen Therapy. Hot Spot 5: 3, August 2003.
36. Hayter, C.R. The Radium Institute of Toronto Hot Spot 5:4, November 2003
37. Hayter, C.R. The Montreal Neurological Institute Hot Spot 6:1, February 2004.
38. Hayter, C.R. Herbert Bruce: Ontario Cancer Visionary Hot Spot 6:2, May 2004
39. Hayter, C.R. The Canadian Society for the History of Medicine. Hot Spot 6:4 November 2004
40. Hayter, C.R. Alfred Hardisty Sellers: Ontario’s pioneer in cancer statistics. Hot Spot 7: 1 February
2005
Abstracts/Presentations
1. New Combined Bone Metastases Clinic: The Ultimate One Stop for Cancer Patients with Bony
Metastases. The Annual Palliative Care Conference, Toronto, Ontario, April 1999.
2. Rapid Response Radiotherapy Program: Survey on Referring Physicians’ Satisfaction. The Annual
Palliative Care Conference, Toronto, Ontario, April 1999.
3. Radiotherapy for Unresectable or Marginally Resectable Osteosarcoma.
The European Cancer Conference, Vienna, Austria, September 1999.
4. Cutaneous and Subcutaneous Ewing’s Sarcoma: An Indolent Disease.
American Society for Therapeutic Radiology and Oncology Annual Meeting, San Antonio, Texas,
October 1999.
5. Palliation of Bone Metastases: A Survey of Patterns of Practice in Canada. 6th Hong Kong
International Cancer Care Conference, Hong Kong, November 1999.
6. Prevalence of Positive CAGE in an Out-Patient Palliative Radiotherapy Clinic.
Canadian Association of Radiation Oncologists’ Annual Meeting, Edmonton, Alberta, September 2000.
3
7. How Accurate are Physicians' Clinical Prediction of Survival and the Available Prognostic Tools in
Estimating Survival Times of Terminally Ill Cancer Patients - A Systematic Review. Palliative Care
11th Annual Conference, Toronto, Ontario, April 2001.
8. International Consensus on Palliative Radiotherapy Endpoints for Future Clinical Trials in Bone
Metastases. American Society for Therapeutic Radiotherapy and Oncology Annual Meeting, San
Francisco, California, November 2001.
9. Successful salvage with percutaneous vertebroplasty for breast cancer patients with osteoporotic
fractures or painful bone metastases failing palliative radiotherapy. Controversies in the Etiology,
Detection and Treatment of Breast Cancer: 2002, Toronto, Ontario, June 2002.
10. A Predictive Model for Survival in Metastatic Cancer Patients Attending an Out-Patient Palliative
Radiotherapy Clinic. 18th UICC International Cancer Congress, Oslo, Norway, June 2002.
11. Successful salvage with percutaneous vertebroplasty for cancer patients with painful bony metastases
failing palliative radiotherapy or with osteoporotic compression fractures. American Society for
Therapeutic Radiotherapy and Oncology Annual Meeting, New Orleans, Louisiana, October 2002.
12. Evaluating remineralization in breast cancer patients with osteolytic bone metastases undergoing
palliative radiotherapy using computerized tomography (CT) density measurements – a feasibility
study. American Society for Therapeutic Radiotherapy and Oncology Annual Meeting, Salt Lake City,
Utah, October 2003.
13. Quality of life after local external beam radiotherapy for symptomatic bone metastases – a
prospective evaluation. American Society for Therapeutic Radiotherapy and Oncology Annual
Meeting, Salt Lake City, Utah, October 2003.
14. Prospective assessment of quality of life following whole brain radiotherapy for brain metastases.
MASCC/ISOO 16th International Symposium Supportive Care in Cancer, Miami Beach, Florida, June
2004.
15. Meaningful change in pain scores in the treatment of bone metastases. MASCC/ISOO 16th
International Symposium Supportive Care in Cancer, Miami Beach, Florida, June 2004.
16. Hayter C, Ege G, Danjoux C. Women Pioneers of Radiotherapy in Canada (poster). Royal College
Annual Meeting, Edmonton, September 2000.
17. Szumacher E, Franssen E, Lewellyn TH, Chow E, Danjoux C, Hayter C, Wong R, Andersson L, Pope J,
Holden L. Patients’ Decisional Preferences in Palliative Radiotherapy for Bone Metastases (preliminary
results; podium). CARO Annual Meeting, Toronto, October 2002. Ibid., 68.
18. Danjoux C, Hayter C, Battista J. The 50th Anniversary of the Cobalt 60 Bomb: A Canadian
Contribution to the War on Cancer (poster). CARO Annual Meeting, Toronto, October 2002. Ibid., 99.
19. Wong RKS, Franssen E, Danjoux C, Bezjak A, Loblaw D, Chow E, Szumacher E, Choo R, Morton G,
Levin W, McLean M, Hayter C, Wilson P, O’Brien M, Taylor D, Fung K. A Randomized Double Blind
Placebo Controlled Trial of Radiotherapy +/- Single Dose Pamidronate for Pain Relief in Patients with
Painful Bone Metastases (poster). CARO Annual meeting, Toronto, October 2002. Ibid., 129.
20. Chow E, Davis L, Hruby G, Holden L, Fung K, Connolly R, Andersson L, Pope J, Loblaw A, Hayter C,
Szumacher E, Kamra J, Wong R, Danjoux C, Quality of life after local external beam radiotherapy for
symptomatic bone metastases – a prospective evaluation, CARO annual meeting 2003, Radiotherapy
and Oncology 69 (2003 supp 1), #95.
21. Lukka H, Hayter C, Warde P, Morris J, Julian J, Gopodarowicz M. Levine M, A randomized trial
comparing two fractionation schemes for patients with localized prostate cancer, CARO annual
meeting 2003, Montreal, Radiotherapy and Oncology 69 (2003 supp 1), #26.
22. H Lukka, C Hayter, P Warde, J Morris, J Julian, M Gospodarowicz, M Levine. McMaster University,
University of Toronto, University of British Columbia, Ontario Clinical Oncology Group, National
Cancer Institute of Canada Clinical Trials Group. A Randomized Trial Comparing Two Fractionation
Schedules for Patients with Localized Prostate Cancer, Int J Radiat Oncol Biol Phys. 2003 Oct 1;57(2
Suppl):S126
23. Holden L, Rubenstein J, Christakis M, Danjoux C, Sixel K, Vidmar M, Connolly R, Finkelstein J,
Szumacher E, Hayter C, Wong R, Chow E. Evaluating remineralization in breast cancer patients with
osteolytic bone metastases undergoing palliative radiotherapy using computerized tomography (CT)
4
24.
25.
26.
27.
density measurements – a feasibility study. Int J Radiat Oncol Biol Phys. 2003 Oct 1;57(2
Suppl):S357-8.
Nyhof-Young J and Hayter C. Evidence-based Resource Development: Formative Evaluation of a
Web-based Virtual Experience in Radiation Oncology Radiotherapy & Oncol 2004 72(Supplement
1):S45(#150)
Holden L, Hayter C. A Survey to Assess Cancer Patients' Awareness of and Interest in Hypnosis for
Pain and Distressing Procedures. (podium) Canadian Association for Psychosocial Oncology annual
meeting, Victoria B.C. April 2005
Hayter C, “Medical History: An Antidote to Physician Burnout,” 38th International Congress on the
History of Medicine, Istanbul, Turkey, Sept 2002.
Tsao MN, Bradley N, Sinclair E, Holden L, Chow E and the RRRP group. Reasons for poor accrual in
a quality of life study involving patients with brain metastases. Canadian Association of Radiation
Oncologists, Halifax, Nova Scotia, September 2004.
28. Bradley N, Sinclair E, Holden L, Chow E, Chan G, Yau V, Danjoux C, Barnes E, Hayter C, Tsao MN
Reasons for poor accrual in a quality of life study involving patients with brain metastases. The
Ontario Provincial Conference on Palliative and End-of-Life Care, Toronto, April 2004.
29. Bradley N, Sinclair E, Holden L, Chow E, Chan G, Yau V, Danjoux C, Barnes E, Hayter C, Tsao MN
Reasons for poor accrual in a quality of life study involving patients with brain metastases. The
Biennial Canadian Neuro-Oncology Meeting, Toronto, May 2004.
30. Bradley N, Sinclair E, Danjoux C, Barnes E, Tsao M, Farhadian M, Yee A, Chow E. The do-notresuscitate order: Incidence of documentation in patient charts of cancer patients referred for
palliative radiotherapy. The Ontario Provincial Conference on Palliative and End-of-Life Care,
Toronto, Ontario, April 3-5, 2005.
31. Doyle M, Barnes E, Tsao M, Chow E, Bradley N, Li K, Sinclair E, Farhadian M, Danjoux C. Referring
physicians expectations of palliative whole brain radiotherapy. The Ontario Provincial Conference on
Palliative and End-of-Life Care, Toronto, Ontario, April 3-5, 2005.
32. Doyle M, Loblaw A, Tsao M, Bradley N, Barnes E, Schueller T, Panzarella T, Sinclair E, Farhadian M,
Chow E. Dexamethasone for the prophylaxis of radiation-induced pain flare following palliative
radiotherapy for bone metastases - a pilot study. The Ontario Provincial Conference on Palliative and
End-of-Life Care, Toronto, Ontario, April 3-5, 2005.
33. Burch S, Bisland S, Bogaards A, Whyne C, Finkelstein J, Wilson B, Yee A: Photodynamic therapy for
the treatment of spinal metastases. A preclinical study. ISSLS, Jun 2004.
34. Burch S, Bisland S, Bogaards A, Whyne C, Wilson B, Finkelstein J, Yee A: Evaluation of spinal
metastases in a preclinical rat model of human breast carcinoma. ISSLS, Jun 2004.
35. Ahn H, Mousavi P, Chin L, Roth S, Finkelstein J, Vitkin A, Whyne C. Tumor Ablation Using Laser
Induced Thermo-Therapy with Vertebroplasty for Spinal Metastases: A Biomechanical Study. CORS,
June 2004.
36. Tschirhart C, Roth S, Whyne C. Effect of Cement Distribution Patterns on Burst Fracture Risk in the
Metastatic Spine Following Percutaneous Vertebroplasty. CORS, June 2004
37. Burch S, Bisland S, Bogaards A, Wilson BC, Whyne C, Finkelstein JA, Yang B, Yee AJ: Evaluation of
spinal metastases in a preclnical rat model of breast carcinoma. Canadian Orthopaedic Association,
Jun 2004.
38. Burch S, Bisland S, Bogaards A, Whyne C, Finkelstein J, Yee A, Wilson B: Photodynamic therapy for
the treatment of spinal metastases: a preclinical study. Canadian Orthopaedic Association, Jun 2004.
39. Ahn H, Mousavi P, Chin L, Roth S, Finkelstein J, Vitkin A, Whyne C. Tumor Ablation Using Laser
Induced Thermo-Therapy with Vertebroplasty for Spinal Metastases: A Biomechanical Study. 50th
Annual Meeting of the Orthopaedic Research Society, March, 2004.
40. Tschirhart C, Roth S, Whyne C. Effects of Cement Location and Geometry on Burst Fracture Risk in
the Metastatic Spine Following Percutaneous Vertebroplasty. 50th Annual Meeting of the Orthopaedic
Research Society, March, 2004.
5
41. Burch S, Bisland SK, Bogaards A, Wilson BC, Whyne CM, Finkelstein JA, Chow E, and Yee AJ.
Photodynamic therapy for the treatment of vertebral metastases. 50th Annual Meeting of the
Orthopaedic Research Society, March, 2004.
42. Burch S, Bisland S, Wilson B, Whyne C, Finkelstein J, Yee AJ: Percutaneous photodynamic therapy for
the treatment of metastatic breast carcinoma to the spine: A novel application. Canadian Breast
Cancer Research Alliance 3rd scientific conference, Oct 2003.
43. Tschirhart C, Nagpurkar A, Whyne CM, Effects of Tumor Location, Shape and Surface Texture on
Burst Fracture Risk in the Metastatic Spine. CORS Winnipeg, October 2003.
44. Ahn H, Mousavi P, Roth SE, Reidy D, Finkelstein J, Whyne CM, Stability of the Metastatic Spine, Pre
and Post Vertebroplasty, In a Cadaveric Biomechanical Model. CORS Winnipeg, October 2003.
45. Mousavi P, Chin L, Ahn H, Roth SE, Finkelstein J, Whyne CM, A Novel Opto-Thermal Technique for
the Ablation of Lytic Spinal Metastases Prior to Cement Injection. CORS Winnipeg, October 2003.
46. Roth SE, Mousavi P, Finkelstein J, Cheung G, Whyne CM, Volumetric Quantification of Cement
Leakage Following Percutaneous Vertebroplasty in Metastatic and Osteoporotic Vertebrae. CORS
Winnipeg, October 2003.
47. Burch S, Yee AJ, Wilson BC, Bisland SK, Bogaards A, Whyne C, Finkelstein J. The novel application of
photodynamic therapy for spinal metastases: Evaluation in a pre-clinical athymic rat model. North
American Spine Society, Oct 2003.
48. Mousavi P., Roth S, Cheung G, Chow E, Finkelstein J, Whyne C. Volumetric Quantification of Cement
Leakage Following Percutaneous Vertebroplasty in Metastatic and Osteoporotic Vertebrae. 49th
Annual Meeting of the Orthopaedic Research Society, February, 2003.
49. Roth S, Rebello M, Kreder H, Whyne C. Venting alone is insufficient in preventing complications in the
prophylactic nailing of femoral metastases. 49th Annual Meeting of the Orthopaedic Research Society,
February, 2003
50. Ahn H, Mousavi P, Roth SE, Reidy D, Finkelstein J, Whyne C. Biomechanical stability of the metastatic
spine pre and post vertebroplasty. 49th Annual Meeting of the Orthopaedic Research Society,
February, 2003
51. Tschirhart C, Nagpurkar A, Whyne C. Parametric Finite Element Analysis of the effects of tumor
location, shape and surface serration on burst fracture risk in the spine. Eleventh Annual Symposium
on Computational Methods in Orthopaedic Biomechanics, February, 2003
52. Roth S, Mousavi P, Ahn H, Chow E, Finkelstein J, Whyne C. Metastatic burst fracture risk prediction.
17th Annual meeting of the North American Spine Society. Oct 29-Nov 2, 2002.
53. Whyne C., Reidy D, Ahn H, Mousavi P, Finkelstein J. A Biomechanical Analysis of Intravertebral
Pressures During Vertebroplasty of Cadaveric Spines With and Without Simulated Metastases. Era of
Hope. Sept 2002.
54. Roth S, Mousavi P, Ahn H, Chow E, Finkelstein J, Whyne C. Metastatic burst fracture risk prediction
using biomechanically based equations. Funding the Quest, Finding the Answers. Canadian Breast
Cancer Foundation, Ontario Chapter. June, 2002.
55. Ahn H., Reidy, D., Finkelstein, J., Mousavi P., Ford M., Whyne C. A Biomechanical Analysis of
Intravertebral Pressures During Vertebroplasty of Cadaveric Spines With and Without Simulated
Metastases. CORS June 2002.
56. Whyne, C., Hu, S., Lotz, J., Biomechanical guidelines for burst fracture prediction in the metastatic
spine. Forty-Sixth Annual Meeting of the Orthopaedic Research Society, Feb 2001.
57. Whyne, C., Hu, S., Lotz, J., Development of guidelines for the prophylactic treatment of
metastatically involved vertebral bodies. Era of Hope, June, 2000.
58. Whyne, C., Hu, S., Lotz, J., Burst fracture risk assessment in the metastatically involved spine. 27th
Annual Meeting of the International Society for Study of the Lumbar Spine, Adelaide, Australia, April,
2000.
59. Whyne, C., Hu, S., Workman, K., Lotz, J., Mechanical Properties of Metastatic Tumors in Bone. FortyFifth Annual Meeting of the Orthopaedic Research Society, March 2000.
6
GRACE CHAN - Oral presentations
Qualitity of Life in Patients with Brain Metastases Treated with a Palliative Course of Radiotherapy in the
Humber College 13th Annual Hospice Palliative Care Conference on 23-25 March 2003.
Determining the Accuracy of Oncology Nurses in predicting the survival of patients with Advanced
Metastatic Cancer. The 15th Annual Provincial Conference on Palliative and End-of-Life Care, April 3-5,
2005.
EMILY SINCLAIR - Oral presentations
Review of Telephone Follow-Up Experience at the Rapid Response Radiotherapy Program (RRRP). The
15th Annual Provincial Conference on Palliative and End-of-Life Care, April 3-5, 2005.
Determining the accuracy of Doctors in Predicting the Survival of Patients with Advanced Metastatic
Cancer. The 15th Annual Provincial Conference on Palliative and End-of-Life Care, April 3-5, 2005.
Determining the Accuracy of Radiation Therapists (MRTT) in predicting the survival of patients with
Advanced Metastatic Cancer. The 15th Annual Provincial Conference on Palliative and End-of-Life Care,
April 3-5, 2005.
GUNITA MITERA, BSc, MRT(T) - Oral presentation
Reasons for Emergency Weekend Radiation Treatment in the Radiation Therapy Department at the
Toronto Sunnybrook Regional Cancer Centre (TSRCC – A Retrospective Review. The 15th Annual
Provincial Conference on Palliative and End-of-Life Care, April 3-5, 2005.
NICOLE BRADLEY
1. Bradley N, Sinclair E, Holden L, Chow E, Chan G, Yau V, Danjoux C, Barnes E, Hayter C, Tsao M.
Reasons for poor accrual in a quality of life study involving patients with brain metastases. The
Ontario Provincial Conference on Palliative and End-of-Life Care, Toronto, April 2004.
2. Bradley N, Sinclair E, Holden L, Chow E, Chan G, Yau V, Danjoux C, Barnes E, Hayter C, Tsao M.
Reasons for poor accrual in a quality of life study involving patients with brain metastases. The
Biennial Canadian Neuro-Oncology Meeting, Toronto, May 2004.
3. Bradley N, Sinclair E, Danjoux C, Barnes E, Tsao M, Farhadian M, Yee A, Chow E. The do-notresuscitate order: Incidence of documentation in patient charts of cancer patients referred for
palliative radiotherapy. The Ontario Provincial Conference on Palliative and End-of-Life Care, Toronto,
Ontario, April 3-5, 2005.
4. Doyle M, Barnes E, Tsao M, Chow E, Bradley N, Li K, Sinclair E, Farhadian M, Danjoux C. Referring
physicians expectations of palliative whole brain radiotherapy. The Ontario Provincial Conference on
Palliative and End-of-Life Care, Toronto, Ontario, April 3-5, 2005.
5. Doyle M, Loblaw A, Tsao M, Bradley N, Barnes E, Schueller T, Panzarella T, Sinclair E, Farhadian M,
Chow E. Dexamethasone for the prophylaxis of radiation-induced pain flare following palliative
radiotherapy for bone metastases - a pilot study. The Ontario Provincial Conference on Palliative and
End-of-Life Care, Toronto, Ontario, April 3-5, 2005.
6. Bradley N, Davis L, Chow E. Symptom distress in patients attending an outpatient palliative
radiotherapy clinic. The Ontario Provincial Conference on Palliative and End-of-Life Care, Toronto,
Ontario, April 3-5, 2005.
7. Wu S, Doyle M, Chow E, Bradley N, Li K. Prevalence of the Prognostic Factors in Patients Attending a
Palliative Radiotherapy Clinic. The Ontario Provincial Conference on Palliative and End-of-Life Care,
Toronto, Ontario, April 3-5, 2005.
Carol Gillies R.T.T.,M.Sc.
Podium and Poster Presentations:
May 2, 2004
Lecture, A Multidisciplinary Collaborative Approach to the Management of Bone
Metastases, International Society Of Radiographers And Radiological Technologists Barbados Association of Radiographers Islands of Technology: Rays of Sunlight,
7
April 25, 2004, A Multidisciplinary Collaborative Approach to the Management of Bone Metastases,
Humber College 14TH Annual Provincial Conference on Palliative and End-of-Life Care,
Toronto, Ontario, Descriptive Poster Oral Presentation
INVITED PRESENTATIONS
1. Practical Use of Radiotherapy in Pain and Symptom Control. 6th Annual Conference. The Science and
Art of Pain and Symptom Management, Toronto, Ontario, November 1999.
2. Complex Pain Issues. Palliative Care 10th Annual Conference, Toronto, Ontario, March 2000.
3. Latest Advances in Bone Metastases. 7th Annual Conference. The Science and Art of Pain and
Symptom Management, Toronto, Ontario, November 2000.
4. Management of Oncological Emergencies. 8th Annual Conference. The Science and Art of Pain and
Symptom Management, Toronto, Ontario, November 2001.
5. Survival Prediction: How important is it and how good are we? Grand Round. Scarborough General
Hospital, Scarborough, Ontario, January 2002.
6. International consensus on palliative radiotherapy endpoints for future clinical trials in bone
metastases. 18th UICC International Cancer Congress, Oslo, Norway, June 2002.
7. ASTRO Refresher Course 417; Bone metastases – strategies to maximize the quality of life. American
Society for Therapeutic Radiotherapy and Oncology Annual Meeting. New Orleans, Louisiana,
October 2002.
8. Palliative Radiotherapy for Bone Metastases. 9th Annual Conference. The Science and Art of Pain
and Symptom Management, Toronto, Ontario, November 2002.
9. Oncological Management of Metastatic Breast Cancer. 13th Annual Hospice Palliative Care
Conference, Toronto, Ontario, March 2003.
10. Survival Prediction – How important is it and how good are we? 13th Annual Hospice Palliative Care
Conference, Toronto, Ontario, March 2003.
11. ASTRO Refresher Course 204: Management of acute/subacute treatment-related complications.
American Society for Therapeutic Radiotherapy and Oncology Annual Meeting, Salt Lake City, Utah,
October 2003.
12. Bisphosphonates: cost, utilization and efficacy. 10th Annual Conference. The Science & Art of Pain
and Symptom Management. Toronto, Ontario, November 2003.
13. Management of locally advanced and metastatic prostate cancer. 14th Annual Ontario Provincial
Conference on Palliative and End of Life Care, Toronto, Ontario, April 2004.
14. Palliative Care Round on management of bone metastases. Scarborough Community Care Access
Centre. September 2004.
15. Management of pathological fractures and spinal cord compression in palliative care. 11th Annual
Conference. The Science & Art of Pain and Symptom Management. Toronto, Ontario, November
2004.
16. Understanding bone pain. Second Annual Conference Advanced Learning in Palliative Medicine.
Tremblant, Quebec, February 2005.
17. Pain and structural effects of external beam radiotherapy. Fifth International Conference on CancerInduced Bone Disease (CIBD). Davos, Switzerland, March 2005.
18. To know or not to know—That is the question. 15th Annual Ontario Provincial Conference on Palliative
and End-of-Life Care. Toronto, Ontario, April 2005.
19. Bone metastases and bone pain: an interdisciplinary approach to a challenging issue. 15th Annual
Ontario Provincial Conference on Palliative and End-of-Life Care. Toronto, Ontario, April 2005.
20. “Medicine for Medics: The Healing Power of History,” Royal College Annual Meeting, Ottawa,
September 21, 2001.
8
Awards
CHARLES ROBERT RUSSELL HAYTER
AWARDS AND DISTINCTIONS
Medical
2001
John B. Neilson Award
Associated Medical Services, Inc.
(The Award shall be offered to a Canadian (not a professional medical historian) who has
made a significant continuing, long-standing contribution to the history of health care in
Canada. It will be made on the basis of contributions of high quality to the discipline, in
the form of noteworthy historical publications, teaching, research, and service to the
community or other significant endeavours)
Committees Chaired:
Chair, Undergraduate Education, Dept of Radiation Oncology, University of Toronto, 2000-2004
Offices held:
Director of Education, TSRCC Radiation Program, 2002 - Present
President, Toronto Medical History Club, 2003 – 4
Committee Member:
U of T Faculty of Medicine Electives Committee, 2001-2004
American Association for the History of Medicine Annual Meeting Committee, 2001-04
List of trainees, electives, fellows, students, etc
CHARLES ROBERT RUSSELL HAYTER - EDUCATIONAL ACTIVITIES
Medical Students Assigned:
Jon-Paul Voroney (4th year elective, March 18-28, 2002)
Malcolm Gibson (4th year elective, Queen’s, April 8-May 3rd 2002)
Allan Lee (2nd year observor, August 19-30, 2002)
Yongjin Wang (IMG observor, October 10, 2002)
Kevin Lai (2nd year observor, October 21, Nov 6, 15, 2002)
Susan Russell (4th year elective, Memorial, October 7-November 1st, 2002)
Alwin Cunje (4th year elective, McMaster, January 6-29, 2003)
Stacey Grossman (4th year ACE), March 13, 2003
Philip Buckler (4th Year ACE), April 15, 2003
Tim Hanna (3rd year elective, June 11 & 18, 2003)
Jane Lea (Ivan Smith student, June 9-July 25, 2003)
Mark Lomaga (3rd year elective, September 15-28, 2003)
Michael Loreto/Annisa Chang (Day of the Doctor, Oct 31, 2003)
Anand Swaminath (elective) Jan 19 – 30, 2004
Ratna Appasani (IMG observor) Apr 14 - May 14, 2004
Stephen Chin (Ivan Smith student) May 3 - Jun 11, 2004
Nisha Mistry Ivan Smith student) Jul 12-Aug 20, 2004
Perry Choi (4th year ACE) Oct 4 – 29, 2004
9
David Bowes (4th year elective) Nov 15 - Dec 3, 2004
University of Toronto- Postgraduate
Dr. Anoo Tamber (Palliative Medicine Fellow, Dec 2-30, 2003)
Dr. Justin Lee (Radiation Oncology Resident, July 1st-September 30, 2004)
Continuing Education and Community Presentations
September 14, 2004
Round Table Discussant: Using the Internet to optimize cancer care,
2nd international onference on Cancer on the Internet, NYC, USA
November 28, 2002
“Hypnosis for Symptom Control: Current Knowledge and Future
Opportunities,” Radiation Oncology Palliative Rounds, TSRCC
February 11, 2002
“Hypnosis for Cancer Pain: Myths and Realities”
8th Annual Palliative Care Awareness Day
Sunnybrook and Women’s College Health Sciences Centre
November 17, 2001
Workshop presenter
“Impending Spinal Cord Compression”
8TH Annual Art and Science of Pain and Symptom Management
Conference, University of Toronto
November 28, 2000-11-24
“From Hypocrates to Hospice: A Historical Perspective on Palliative
Medicine”
Radiation Oncology Palliative Rounds
T-SRCC
November 18, 2000
Interactive Palliative Workshop for RTTs
University of Toronto
“What is s/he thinking?: Approaching a palliative patient”
November 17, 2000
7th Annual Conference on Science & Art of Pain and Symptom
Management
University of Toronto
“Management of Pain and Symptoms with Palliative Radiotherapy”
March 25, 1999
Queen’s CME, Kingston
“Palliative Radiotherapy for Family Physicians”
Carol Gillies R.T.T.,M.Sc.
Research mentorship – Radiation Therapy students:
2003 – 2004:
Maria-Theresa de Borja
The Correlation Between Karnofsky and ECOG Performance Status Scales
•
•
Research Supervisors: Edward Chow, Carol Gillies
Recipient of the 2004 University of Toronto Radiation Sciences Program Research Award
Humber College 14TH Annual Provincial Conference on Palliative and End-of-Life Care,
Toronto, Ontario, April 25, 2004, Scientific Poster Oral Presentation
10
•
•
•
Recipient of the 14th Annual Ontario Provincial Conference on Palliative and End-of-Life Care
Oral Poster Presentation Award
Recipient of the OAMRT Ed Carpen Student Exhibit Award
Recipient of the CAMRT Dr. Marshall Mallet Student Exhibit Award
Michelle Greig
Level of Concordance Between Proxy and Cancer Patient’s Ratings in Brief Pain Inventory
Research Supervisors: Edward Chow, Carol Gillies
•
Humber College 14TH Annual Provincial Conference on Palliative and End-of-Life Care, Toronto,
Ontario, April 25, 2004, Invited Oral Presentation
Course Development:
Gillies C, Hayter C, Holden L, Szumacher E, Yee A, Course on the
Feb. 2002
Management of Bone Metastases for Fellows and Residents in Orthopedics,
Family Medicine, Radiology, Medical & Radiation Oncology, Radiation
Therapy – Workshop C: Radiation Therapist Trainees, Toronto Sunnybrook
Regional Cancer Centre and Sunnybrook & Women's College Health Science
Centre, Toronto
11
Videoconferencing: PROG-O
See Appendix __ for evaluation summary.
12
Books, Book Chapters
1. Perrin RG, Laperriere NJ, Loblaw DA, Laxton AW. Spinal axis metastases. In Levin VA, ed. Cancer in
the Nervous System, 2nd edition. Oxford University Press, New York; 2002.
2. Loblaw DA, Laperriere N, To T, Cohen M, Detsky AS. Accuracy of a linked administrative database of
malignant spinal cord compression in Ontario cancer patients. Thesis. University of Toronto; 2002
(Submitted)
Other
1. Gillies C. Research Co-Supervisors: Chow E, Danjoux C, and Finkelstein J. An integrated clinic model
for the multidisciplinary management of bone metastases. A project/dissertation in partial fulfillment
of the requirements of Anglia Polytechnic University for the degree of Master of Science Radiography
(Therapeutic).
Posters, Presentations and Published Abstracts
Course on the Management of Bone Metastases: Toronto Sunnybrook Regional Cancer
Centre, Toronto, Ontario. February 22, 2002
Andersson L, Danjoux C, Christakis M, Finkelstein J, Stephen D. Workshop A: Orthopedic /
Radiology.
Berry S, Ford M, Librach L, Pope J, Wu J. Workshop B: Radiation / Medical Oncology and Palliative
Medicine.
Holden L, Gillies C, Yee A, Szumacher E, Hayter C. Workshop C: Radiation therapist trainees.
Michener Institute: Toronto, Ontario. April 9, 2002.
Holden L. Radiation therapy in the Rapid Response Radiotherapy Program.
Danjoux C. Palliative radiotherapy.
Humber College Palliative Care 12th Annual Conference; Royal York Hotel, Toronto.
May 5 – 7, 2002
Szumacher E, Chow E, Danjoux C, Hayter C, Holden L, Andersson L, Franssen E, Adams L.
Comprehensive geriatric assessment as an indicator of health related quality of life in elderly patients
with advanced cancer (review of the literature). Humber College Palliative Care 12th Annual
Conference, Royal York Hotel, Toronto. May 5 – 7, 2002. Poster #8.
Chow E, Fung KW, Panzarella T, Bezjak A, Danjoux C, Tannock I. A predictive model for survival in
metastatic cancer patients. Humber College Palliative Care 12th Annual Conference, Royal York Hotel,
Toronto, May 5 – 7, 2002. Poster #11.
Holden L, Cheung G, Chow E, Finkelstein J, Danjoux C. Prospective evaluation of functional status
and quality of life in patients undergoing percutaneous vertebroplasty. Humber College Palliative
Care 12th Annual Conference, Royal York Hotel, Toronto, May 5 – 7, 2002. Abstract #500-B.
13
18th UICC International Cancer Congress: Oslo, Norway. June 30 – July 5, 2002.
Holden L, Cheung G, Chow E, Finkelstein J, Danjoux C. Prospective Evaluation of functional status
and quality of life in patients undergoing percutaneous vertebroplasty. Abstract O206.
12th International Conference on Cancer Nursing – 2002: London, United Kingdom. August
28 – September 1, 2002
Andersson L, Horvath N, Stefaniuk K, Librach L. Pain Clinic Accessibility: An essential component of
palliative care in oncology patients. Oral presentation and poster. Abstract #82.
Andersson L, Chow E, Wong R, Vachon M, Hruby G, Franssen E, Pope J, Szumacher E, Hayter C,
Danjoux C. Patients understanding of their own illness and expectation of rapid response
radiotherapy. Oral presentation. Abstract #57.
12th ISRRT World Congress: Amsterdam, Holland. September 20 – 24, 2002
Holden L, Cheung G, Chow E, Finkelstein J, Danjoux C. Prospective Evaluation of functional status
and quality of life in patients undergoing percutaneous vertebroplasty. Page 20.
ASTRO Annual Meeting; New Orleans, Louisiana. October 6 – 12, 2002
Chow E, Cheung G, Holden L, Vidmar M, Danjoux C, Finkelstein J. Successful salvage with
percutaneous vertebroplasty for cancer patients with painful bony metastases failing palliative
radiotherapy. Abstract #80.
CARO Annual Meeting; Toronto. October 25 – 27, 2002
Szumacher E, Franssen E, Lewellyn TH, Chow E, Danjoux C, Hayter C, Wong R, Andersson L, Pope J,
Holden L. Patient’s decisional preferences in palliative radiotherapy for bone metastases (preliminary
results). Radiother Oncol 2002; 65 (supplement 1): S16. Abstract #68.
Chow E, Cheung G, Holden L, Vidmar M, Danjoux C, Finkelstein J. Successful salvage with
percutaneous vertebroplasty for cancer patients with painful bony metastases failing palliative
radiotherapy. Radiother Oncol 2002; 65 (supplement 1): S30. Abstract #128.
Wong RKS, Franssen E, Danjoux C, Bezjak A, Loblaw DA, Chow E, Szumacher E, Choo R, Morton G,
Levin W, McLean M, Hayter C, Wilson P, O’Brien M, Taylor D, Fung K. A randomized double blind
placebo controlled trial of radiotherapy +/- single dose pamidronate for pain relief in patients with
painful bone metastases. Radiother Oncol 2002; 65 (supplement 1): S31. Abstract #129.
Loblaw DA, Laperriere N, Cohen M, To T, Mackillop WJ, Detsky AS. Lessons learned from an
electronic database comparison and chart reabstraction audit of a population-based, linked
administrative database. Radiother Oncol 2002; 65 (supplement 1): S34. Abstract #142.
Loblaw DA, Laperriere N, To T, Cohen M, Mackillop WJ, Detsky AS. Chart reabstraction study
assessing the accuracy of a population-based, linked administrative database of malignant spinal cord
compression. Radiother Oncol 2002; 65 (supplement 1): S34. Abstract #144.
“Bone Pain” Conference; Regional Palliative Pain and Symptom Management Service: St.
Catharines, Ontario. November 13, 2002.
14
Holden L, Cheung G, Chow E, Finkelstein J, Connolly R, Danjoux C. Percutaneous Vertebroplasty. An
Evolving Strategy.
Awards
Ms. Lou Andersson – 2002 Excellence in Nursing; Canadian Association of Nurses in Oncology (CANO)
Dr. Cyril Danjoux – 2001-2002 Award for Excellence in Innovation in Continuing Education at the
Sunnybrook and Women's College Health Sciences Centre; Peters-Boyd Academy Faculty
Educational Electives
The RRRP provides a half-day elective for health care workers to experience the activities of the RRRP
clinics. Some of the participants in those electives were:
Newly hired oncology nursing staff and nursing visitors
Medical Students
Community Health Care Professionals
Clinical Trials
We participate in several clinical trials. Attachment C provides a summary of current active studies.
15
PROG-O (Palliative Radiation Oncology Group Ontario)
Our collaboration with PMH and Hamilton Regional Cancer Centre Palliation Radiation Oncology Group led
to the formation of the Palliative Radiotherapy Oncology Group Ontario (PROG-O). In November 2001,
Ottawa Regional Cancer Centre became involved in PROG-O. Currently, this group meets monthly
through video conference. This has improved communication between the staff involved in the palliative
radiotherapy program in those centres and offered the opportunity for collaboration in research. These
are scheduled on the fourth Tuesday of every month 8:00 – 9:30 a.m.
The subjects discussed during 2004 were:
Sept 28
Oct 26
Nov 30
An Overview on Art Therapy & Music Therapy
Money Worries: Research about Financial Issues for People with
Cancer
Love, Learning and Listening - The Art of Communication in
Palliative Care
Susan Watson
Ross Gray, and Judy
Gould
Brian Berger
The subjects discussed during 2003 were:
January 14
March 11
Improving neurologic outcomes in malignant spinal cord
compression
A revisit of and International Trial of single vs. multi-fraction reirradiation for painful bone metastases
Assessment of planning CT in palliative radiotherapy
April
Rounds cancelled
February 11
Dr. Andrew Loblaw
Dr. Jackson Wu
Drs. Haddad and R.
Wong
The subjects discussed during 2002 were:
January 29
March 26
April 30
May 28
October 22
November 12
December 10
In search of the best palliative RT schedule for lung cancer
Examining a novel neuroprotectant in malignant spinal cord
compression: human recombinany erythropoetin
Determination of the patient expectation of a clinically relevant
partial response as achieved with palliative external beam
radiotherapy for bone metastases
Physicians’ expectation of palliative bone radiation – where do we
go from here?
Single Dose Pamidronate and External Beam Radiotherapy for
Painful Bone Metastases - Does it work?”
Quality of life in patients with brain metastases treated with a
palliative course of radiotherapy
Is a trial of immediate vs. delayed radiotherapy for asymptomatic
brain metastases feasible?
Dr. Andrea Bezjak
Dr. Andrew Loblaw
Dr. Edward Chow
Dr. Paula Wilson
Dr. Rebecca Wong
Dr. May Tsao,
Ms. Grace Chan
Dr. Edward Chow
Dr. Peiman Haddad
The subjects discussed during 2001 were:
Feb 6
Feb 27
Mar 27
May 22
The Pain of Measuring Pain
The Pain of Measuring Pain – Part II
Palliative Radiation Therapy: Outcomes Unknown?
Design and Evaluation of a Strategy to Improve Information Needs
Dr. Jonathan Sussman
Dr. Jonathan Sussman
Ms. Angela Turner
Mr. Stephen Scott
16
in Patients Living With Advanced Cancer – Part II
Jun 26
Oct 2
Oct 30
Nov 27
Dec 18
Ms. Joan Pope
PROP team
Dr. Lisa Barbera
An Evidence Based Epidemiologic Approach to Estimating RT
Needs for Lung Cancer (cancelled)
Update of 2000-2001 and Fentanyl Study
A Randomized Study for Management of SVCO
International Consensus on Palliative Radiotherapy Endpoints for
Future Clinical Trials in Bone Metastases and Retreatment Trial
Proposal
Percutaneous Vertebroplasty and Oncology
Dr. Rebecca Wong and
Cyril Danjoux
Dr. Paula Wilson
Dr. Jackson Wu
Dr. Gordon Cheung and
Dr. Walter Montanera
,
,
17
RRRP and BMC Monthly Meetings
We have monthly research rounds at TSRCC, scheduled on the second Tuesday of every month.
The subjects discussed during 2004 were:
Jan 20
Apr 20
March 18
Jun 15
Sept 21
Oct 19
Nov 16
Bench Percutaneous Vertebroplasty /
Biomechanics
Medical Oncology
Measuring fatigue
Bone Mets Clinic
Annual Business meeting
Minimally Invasive Management of
Vertebral Compression Fractures
Using Ultrasound to Follow Tumor Changes
in Response to Therapy
Drs. Joel Finkelstein and Dr. Andrew Loblaw
Drs. Mark Clemons & Maureen Trudeau
Dr. Marg Fitch
Drs. Edward Chow, Albert Yee and team
members
Dr. Michael Ford
Dr. Gregory Czarnota
The subjects discussed during 2003 were:
Jan 21
March 18
May 20
June 17
Jul 15
Aug 19
Nov 18
Dec 16
Current update on the Rx of breast mets –
bisphosphonates
Measuring fatigue
Radiology of bone metastases
Impending/pathological fractures of the
hip/lower extremity
Clinical Trial on burst fracture prediction
Clinical Percutaneous Vertebroplasty
Orth/Health Research/Spinal Cord
Compression
Business Meeting / Special Requests
Dr. Maureen Trudeau
Dr. Marg Fitch
Dr. Monique Christakis
Dr. Hans Kreder
Sandie Roth and Dr. Finkelstein
Dr. Gordon Cheung
Dr. Joel Findelstein & Dr. Andrew Loblaw
Open Forum
The subjects discussed during 2002 were:
January 11
February 8
March 8
May 10
November 19
December 17
Supportive care needs study
Pain management
Patient decisional preferences for treatment using palliative
radiotherapy
Hypnosis for cancer pain
Biomechanics
Communications with referring physicians/fatigue
Dr. Marg Fitch
Dr. Larry Librach
Dr. Ewa Szumacher
Dr. Charles Hayter
Dr. Cari Whyne
Dr. Toni Barnes
The subjects discussed during 2001 were:
Oct 12
Nov 9
Percutaneous Vertebroplasty
Spinal Cord Compression
Dr. Gordon Cheung
Dr. Andrew Loblaw and
Dr. Joel Finkelstein
18
APPENDIX A
Rapid Response Radiotherapy Palliative Clinics
http://www.tsrcc.on.ca/RRRP.htm
Staff: Ms. L. Andersson (Nursing), Dr. E. Chow (Rad Onc), Dr. C. Danjoux (Rad Onc), Dr. C. Hayter
(Rad Onc), Ms. L. Holden (RT), Ms. J. Pope (Nursing), Ms. T. Schueller (Pharmacy), Ms. K. Stefaniuk
(Pharmacy), Dr. E. Szumacher (Rad Onc), Dr. T. Barnes (Rad Onc), and Dr. A. Loblaw (Rad Onc), Dr. M.
Fitch and Ms. M. Winterhoff (Social Service) and Dr. M. Branigan (Palliative Medicine).
Objective:
Provide expedited access for symptom relief from incurable cancers in patients with limited life
expectancies.
Eligible Patients:
1. Symptomatic cancer (any disease site) where palliative radiotherapy may be indicated.
2. Patients with life expectancies of <6 months.
3. A “most responsible physician” available to provide follow-up and ongoing oncological care upon
completion of the RRRP consultations.
Ineligible Patients:
1. Candidates for potentially curative treatments.
2. Patients requiring further investigations before radiotherapy opinion can be rendered.
3. Patients who are currently actively being followed by a radiation oncologist at T-SRCC (unless
otherwise specifically arranged).
4. Patients whose disease status is better served by a radiation oncologist who could provide
longitudinal follow-up.
5. Off-service in-patients who require transfer of care to radiation oncology for ongoing oncological
care.
Monday
Tuesday
Wednesday
Thursday
Friday
Dr. T. Barnes
Dr. T. Barnes/Dr. L. Barbera
Dr. C. Danjoux
Dr. E. Chow
Dr. M. Tsao
Sim 4
Sim 4
Sim 4
Sim 4
Sim 4
To make a referral:
1. Contact the new patient booking office and request a referral to the Rapid Response clinic.
2. Contact the RRRP nurse 480-5897.
3. Contact one of the RRRP physicians directly.
19
APPENDIX B
Decision Tree for Patients Referred to RRRP / BMC (January 2001)
Yes
No
Yes
No
Is patient new to T-SRCC?
Did patient see a T-SRCC Rad Onc?
No
Is patient estimated survival
greater than 6 months?
Yes
Refer to his / her Rad Onc
To site group based on diagnosis
- lung
What is the urgency of appointment?
- breast
- GU etc.
Emergency
Urgent
< 24 h
<1 week
(Cord Compression
(Bleeding,
SVCO)
SOB)
No
Elective
Book next available RRRP slot
Do not book beyond 2 weeks
Is RRRP slot available? Yes
Discuss with RRRP Rad Onc who has a
clinic for that day or next few days.
Is RRRP Rad Onc able to see patient?
Yes
-
overbook patient to Rad Onc in RRRP
inform ref MD and patient
No
Refer to Rad Onc on call
nd
** RRRP Policy circulated as addendum to Minutes of Radiation Oncology staff meeting of March 2 2000
20
APPENDIX C
Jan 1999: Initiated Bone Metastases Clinic (BMC)
A bi-weekly Bone Metastasis Clinic (BMC) started operation at the T-SRCC on January 8, 1999. The clinic
is staffed by Orthopaedic Surgical Oncologists: Drs. T. Axelrod, J. Finkelstein, D. Stephen, and M. Ford
and A. Yee; Radiation Oncologists: Drs. E. Chow, C. Danjoux, C Hayter, J. Kamra, A. Loblaw, and E.
Szumacher; and Dr. Librach (palliative care physician).
The BMC is held on the 2nd and 4th Friday morning of each month in clinic C at the TSRCC.
The goals of the BMC are to:
1. Provide an elective orthopaedic consultation service for patients with bone metastasis referred by TSRCC oncologists; Provide elective radiation oncology consultations to patients with bone metastasis
referred by SWHSC physicians.
2. Provide elective orthopaedic and radiation oncology consultations to patients with bone metastasis
referred by community physicians.
3. Provide follow-up to oncology patients after orthopaedic interventions.
Bone Metastases Clinic – 2nd and 4th Friday (Clinic C)
To make a referral:
1. Contact the new patient booking office and request referral to the Bone metastases
clinic.
2. Contact the RRRP nurse 480-5897.
3. Contact one of the RRRP physicians directly.
21
APPENDIX D
Clinical Trials for Palliative Patients
Brain Metastases
Bone Metastases
Phase III study of accelerated whole brain irradiation
for patients with brain metastases of good
performance status not suitable for surgical resection
PI: Dr. P. Davey
Procedure:
• Patients randomized to either 20 Gy/5/1 week or 40
Gy/20/2 weeks
Eligibility:
• ECOG 0, 1, or 2
• Predicted survival > 6
Contact: Keitha McMurry p 7341
Palliative radiotherapy for bone metastases: Patients’
treatment preferences
PI: Dr. E. Szumacher
Procedure:
• Patients complete a questionnaire about their desire to
participate in treatment decisions
• Patients who wish to participate in treatment decision
board to aid their decision between 2 treatment
regimens (8 Gy/1; 2000 Gy/5)
Contact: Dr. E. Szumacher x 4982
Quality of life and proxy agreement in patients with
brain metastases treated with a palliative course of
radiotherapy
PI: Dr. May Tsao, Dr. Edward Chow, Ms. Grace Chan
Procedure:
• prospective collection of quality of life outcomes
Eligibility:
• ability to read/understand English
• availability of proxy/caregiver
Contact: Dr. M. Tsao x 4806
Determination of the Patient Expectation of a
Clinically Relevant Partial Response as Achieved with
Palliative External Beam Radiotherapy for Bone
Metastases
PI: Dr. E. Chow
Procedure:
• 15-minute patient interview, pre-treatment, and two
month post last treatment
Eligibility:
• Bone mets treated with palliative XRT
• ability to read/understand English
• bone pain of ≥ three on a numerical scale of 0 – 10
Contact: Dr. E. Chow x 4998
GI, LUNG
Breast Cancer
Evaluation of remineralization due to radiotherapy for
breast cancer patients with osteolytic bone
metastases using CT density measurements
PI: Dr. E. Chow
Procedure:
• 8 Gy/1; 20 Gy/5; 30 Gy/10
• CT of area of interest pre XRT & 3 months post XRT
• Telephone assessment of pain and analgesic requirement
at weeks 1,2,3,8 and 12 post XRT
Eligibility:
• Long bones/ vertebrae
• Expected survival > 4 months
Ineligibility:
• Pathological Fracture
• Cord compression
• Previous XRT to site of concern
Contact: Lori Holden x 7044
Anorexia & Cachexia
Phase III double blind, Placebo-Controlled
Randomized Comparison of Megace vs an N-3 Fatty
Acid Enriched Nutritional Supplement vs. both for the
treatment of Cancer Cachexia and Anorexia (NCIC
CTG).
PI: Dr. R. Wong
Procedure:
• Megace Liquid 600 mg qid + placebo PA vs. placebo
Megace+EPA
• vs Megace+EPA
Eligibility:
• Life expectancy > 3m, ECOG < 2 + Wt. Lost > 5lbs in 2
months
Ineligible:
• Breast, Endometrium, Ovary, Prostate
• Long terms steroids
• Bowel obstruction
• History of Pulmonary Embolins/DVT
• Diabetics on Insulin
Contact: Dr. R. Wong: 416-946-2919
22
All Histologies
Pre- and Post- radiation oncology consultation survey on patients with advanced cancer for the
understanding of their illness and expectations from palliative radiotherapy for symptomatic metastases
PI: Ms. Lou Andersson, Dr. Edward Chow
Procedure:
• survey prior to seeing radiation oncologist and again after consultation
Eligibility:
• speak English
• ability to give written consent
Contact: Ms. L. Andersson x 5897
23
APPENDIX E
CONTENT OF PREVIOUS ISSUES AND INSERTS OF HOT SPOT
Volume 1, Issue
1
February 1999
Volume 1, Issue
2
May 1999
Insert
May 1999
Editor’s Corner
From the Chief Executive Officer
The first RRRP newsletter
Palliative radiotherapy rounds
New combined bone metastases clinic
A phase II trial of palliative radiotherapy for metastatic renal cell carcinoma
Prospective assessment of symptom palliation for patients attending a rapid
response radiotherapy program
The challenge of speedy delivery of pain relief met by the rapid response clinic
at T-SRCC
The cancer pain and palliative care clinic at T-SRCC
Research Corner
Dr. Ken Shumak
Dr. Gillian Thomas
Dr. Ewa Szumacher
Drs. Joel Finkelstein and Edward Chow
Drs. Edward Chow and Padraig Warde
Drs. Edward Chow, Cyril Danjoux, and
Rebecca Wong
Dr. Ewa Szumacher and Ms. Lou
Andersson
Dr. Larry Librach
Dr. Rebecca Wong
Message from the Chief Executive Officer
A note of thanks
Editor’s Corner
Differentiating normal grief from clinical depression
Ontario Drug Benefit (ODB) Formulary Changes
Surgical management of metastatic spine disease
Radiosurgery for brain metastases
Surgical management of metastatic extremity lesions
Highlights in the Multinational Association of Supportive Care Cancer
Dr. Carol Sawka
Ms. Ruth Connolly and Dr. Edward Chow
Dr. Mary Vachon
Ms. Trudi Schueller
Dr. Joel Finkelstein
Dr. Phillip Davey
Dr. David Stephen
Dr. Rebecca Wong
Cancer Related Pain Management
Dr. David Warr
Sponsored by Janssen-Ortho Inc.
Volume 1, Issue
Referring physicians’ satisfaction with the RRRP
Ms. Ruth Connolly and Dr. Edward Chow
CONTENT OF PREVIOUS ISSUES AND INSERTS OF HOT SPOT
3
August 1999
Insert
August 1999
Preparing the community and health care professionals for new challenges in
palliative care – a new endeavour of the rapid response radiotherapy program
Editor’s Corner
Management of bone metastases with external beam radiotherapy
Single dose wide field radiotherapy
Bisphosphonates in palliative care
Mitoxantrone and prednisone for hormone refractory prostate cancer
Research Corner
Ms. Lou Andersson and Dr. Ewa
Szumacher
Drs. Ewa Szumacher and Rebecca Wong
Dr. Cyril Danjoux
Dr. Sandeep Sehdev
Dr. Scott Berry
Dr. Rebecca Wong
Malignant wound management
Dr. Valerie Schultz
Sponsored by Convatec
Volume 1, Issue
4
November 1999
Insert
November 1999
Bayview Support Network: Ontario’s first on-site cancer support network
Ms. Mridula Sood
Dope and cope: it is no longer enough
Editor’s comment
Psychosocial issues with a cancer diagnosis
Cancer care at York Central Hospital
Yee Hong palliative care services: A culturally sensitive approach
Hill House – A Richmond Hill hospice
Charles R.R. Hayter, MD, BA, MA, FRCPC joins T-SRCC
Interview with Russell Goldman, MD, CCFP, palliative care physician with the
Temmy Latner Centre for Palliative Care, Mount Sinai Hospital
Research Corner
Dr. Michele Chaban
Bowel Obstruction
Management of Radiotherapy-Induced Acute Gastrointestinal Toxicities
Dr. Margaret Fitch
Ms. Jane Anderson
Dr. Stanley Zheng
Ms. Ann Gold
Dr. Rebecca Wong
Dr. Larry Librach
Dr. Rebecca Wong
Sponsored by Novartis Pharmaceuticals
26
CONTENT OF PREVIOUS ISSUES AND INSERTS OF HOT SPOT
Canada, Inc.
Volume 2, Issue
1
February 2000
Insert
February 2000
Volume 2, Issue
2
May 2000
Insert
Editor’s comments
Advance care planning for people with cancer
The emotional needs of the person with advanced cancer
Historical Vignette: The beginnings of palliative radiotherapy in Canada
When does palliative care begin?
Palliative radiation oncology program at the Princess Margaret Hospital
Ask the Experts
Research Corner
Prevention and treatment of radiation-induced emesis
Prevention and treatment of chemotherapy-induced nausea and vomiting
(N&V)
From the associate editor’s desk
Enhancing culturally sensitive practice when caring for seriously ill patients
and their families
Quality end-of-life care: What do patients think?
Family dealing with advanced cancer
Percutaneous vertebroplasty / cementoplasty at bone metastases clinic,
TSRCC
Historical Vignette: Dr. Joseph-Ernest Gendreau and the early use of radium
Research Corner
Accessing palliative care in your community
Dr.
Dr.
Dr.
Dr.
Dr.
Dr.
Dr.
Scott Berry
Mary Vachon
Charles Hayter
Larry Librach
Andrea Bezjak
Rebecca Wong
Rebecca Wong
Dr. Rebecca Wong
Mr. Carlo De Angelis
Sponsored by Glaxo-Wellcome
Dr. Edward Chow
Dr. Elizabeth Latimer
Dr. Scott Berry
Dr. Mary Vachon
Dr. Edward Chow
Dr. Charles Hayter
Dr. Rebecca Wong
Ms. Joan Pope and Ms. Lou Andersson
27
CONTENT OF PREVIOUS ISSUES AND INSERTS OF HOT SPOT
May 2000
Volume 2, Issue
3
August 2000
From the editorial board
When the patient of a young child is seriously ill
Disclosure
Utilization of complementary therapies in palliative care
Historical Vignette: Private radiotherapy in Canada
Research Corner – Summer research for the Rapid Response Radiotherapy
Program
Andrew Loblaw, MD, FRCPC, joins T-SRCC
Insert
August 2000
Volume 2, Issue
4
November 2000
Dr. Ewa Szumacher and Ms. Ruth Connolly
Dr. Mary Vachon
Dr. Philip Hebert
Ms. Ruth Connolly
Dr. Charles Hayter
Dr. Rebecca Wong
Nutrition and cancer
The ABCs of vitamins and minerals
Ms. Elaine Posluns
Ms. Elaine Posluns
Supported by Novartis Pharmaceuticals
Canada, Inc.
Editor’s Corner
Report from the “tri-centre” meeting with Dr. William E. Powers
Adolescents living with a parent with advanced illness
Resources on the Internet for improving end-of-life care – How to get started
Historical Vignette: Vera Peters: Canadian pioneer in psychosocial oncology
Research Corner – Informational needs assessment on patients receiving
palliative radiotherapy
Seventh Annual Conference – The Science and Art of Pain and Symptom
Management
Dr. Rebecca Wong
Dr. Jackson Wu
Dr. Mary Vachon
Dr. Scott Berry
Dr. Charles Hayter
Dr. Rebecca Wong
28
CONTENT OF PREVIOUS ISSUES AND INSERTS OF HOT SPOT
Insert
November 2000
Volume 3, Issue
1
February 2001
Insert
February 2001
Cancer-related fatigue
Algorithm for managing cancer-related fatigue
Dr. Rebecca Wong
Dr. Rebecca Wong
Supported by Janssen-Ortho Inc.
From the associate editor’s desk
Dr. Maureen Trudeau
Staff stress and suffering
Historical Vignette: Cancer care before medicare
Pain and symptom management conference
Follow-up for breast cancer
Research Corner – Shared treatment decision-making
Thank you…
Dr.
Dr.
Dr.
Dr.
Hormones in Breast Cancer
Dr. Maureen Trudeau
Metastatic Breast Cancer
Dr. Maureen Trudeau
Supported by Astra-Zeneca Canada Inc.
Dr. Maureen Trudeau
Dr. Maureen Trudeau
Supported by Aventis
Dr. Maureen Trudeau
Supported by Hoffman LaRoche
Chemotherapy in Metastatic Breast Cancer Treatment
Treatment of Systemic Recurrence with Chemotherapy
Herceptin
Volume 3, Issue
2
May 2001
From the guest editor's desk
Addressing spiritual needs
When the shrink gets cancer and gets spiritually transformed
Historical Vignette: The history of hospices
Edward Chow
Kathleen Pritchard
Mary Vachon
Charles Hayter
Dr. Eva Grunfeld
Dr. Rebecca Wong
Dr.
Dr.
Dr.
Dr.
Charles Hayter
Sharon Grant
Mary Vachon
Charles Hayter
29
CONTENT OF PREVIOUS ISSUES AND INSERTS OF HOT SPOT
Insert
May 2001
Volume 3, Issue
3
August 2001
Insert
August 2001
Volume 3, Issue
4
November 2001
Ethics: Caring for patients with different faiths
Research Corner - Patient expectations
Notice regarding treatment delays...
Dr. Scott Berry
Dr. Rebecca Wong
A guide to spiritual care of the caregiver
A guide to spiritual assessment of cancer patients
Dr. Michele Chaban
Dr. Michele Chaban
Supported by AstraZeneca Canada Inc.
and Purdue Pharma
From the editor's desk
Comfort and stress among cancer caregivers
On suffering in terminal illness
Historical Vignette: The history of morphine
Research Corner
Dr.
Dr.
Dr.
Dr.
Dr.
Palliation in lung cancer
From the guest editor's desk
Survey shows 40% of RRRP patients arrive with missing info: A plea for help
Finding meaning in life in the face of advancing cancer
Historical Vignette: The 50th anniversary of cobalt treatment
Tough decisions about funding for new palliative therapies: How do we
decide?
Research Corner
Cyril Danjoux
Eva Grunfeld
Mary Vachon
Charles Hayter
Rebecca Wong
Dr. Andrea Bezjak, Dr. Catherine Heath,
Ms. Jane Lea
Supported by AstraZeneca Inc. and
Purdue Pharma
Dr. D. Andrew Loblaw and Ms. Lori Holden
Dr. Charles Hayter and Ms. Ruth Connolly
Dr. Mary Vachon
Dr. Charles Hayter
Dr. Scott Berry
Dr. Rebecca Wong
30
CONTENT OF PREVIOUS ISSUES AND INSERTS OF HOT SPOT
Insert
November 2001
Volume 4, Issue
1
February 2002
Insert
February 2002
Volume 4, Issue
2
May 2002
Insert
May 2002
Malignant Spinal Cord Compression
Dr. D. Andrew Loblaw and Ms. Lori Holden
Partially supported by Purdue Pharma
From the editor's desk
Advance notice of the ninth annual conference on the science and art of pain
and symptom management
Denial and minimization in advanced cancer
Global health ethics and palliative care
Historical Vignette: The story of Essiac
Research Corner
Dr. Ewa Szumacher and Ms. Joan Pope
Oral health care in the patient with cancer
Mouth care for radiation patients
Dr. Trey Petty
Dr. Alex Hammond
Supported by Biotene Canada, Division of
Bolton Dental Mfg. Inc.
From the associate editor’s desk
New chiefs at TSRCC and University of Toronto
Depression in advanced cancer
Historical Vignette: Blood and medicine
Hope for a good death
Research Corner
Dr.
Dr.
Dr.
Dr.
Dr.
Dr.
Anemia in hematology and medical/radiation oncology
Dr. Gerard Morton and Dr. Rena Buckstein
Supported by Ortho Biotech
Dr.
Dr.
Dr.
Dr.
Mary Vachon
Scott Berry
Charles Hayter
Rebecca Wong
Edward Chow
Edward Chow and Dr. Cyril Danjoux
Mary Vachon
Charles Hayter
Monica Branigan
Rebecca Wong
31
CONTENT OF PREVIOUS ISSUES AND INSERTS OF HOT SPOT
Volume 4, Issue
3
August 2002
Insert
August 2002
Volume 4, Issue
4
November 2002
From the associate editor’s desk
TSRCC pharmacy services
The transformation from tragedy into grace in terminal illness – part one
Historical Vignette: Plants, poisons and potions: Drug treatments for cancer
TSRCC pharmacy assists Third World countries
Informed decision-making in palliative care
Research Corner
Ms. Lou Andersson and Dr. Cyril Danjoux
Ms. Kim Stefaniuk
Dr. Mary Vachon
Dr. Charles Hayter
Ms. Kim Stefaniuk
Dr. Scott Berry
Dr. May Tsao and Dr. Rebecca Wong
Accessing medication
Ms. Kim Stefaniuk
Supported by Amgen Canada Inc. and
Abbott Laboratories
From the associate editor’s desk
Palliative care is not euthanasia
The transformation from tragedy into grace in terminal illness – part two
Palliative care at the University of Texas M.D. Anderson Cancer Center
Historical Vignette: Charles Huggins: The Canadian who discovered hormone
therapy for prostate cancer
Research Corner
Award of Excellence
Dr.
Dr.
Dr.
Dr.
Insert
November 2002
Expanded role of hormone therapy as neoadjuvant or adjuvant therapy in
prostate cancer patients undergoing definitive treatment
Volume 5, Issue
From the editor’s desk
Edward Chow
Monica Branigan
Mary Vachon
Toni Barnes
Dr. Charles Hayter
Dr. Rebecca Wong
Dr. Cyril Danjoux
Dr. Richard Choo
Supported by Aventis
Dr. Cyril Danjoux and Dr. Edward Chow
32
CONTENT OF PREVIOUS ISSUES AND INSERTS OF HOT SPOT
1
February 2003
Insert
February 2003
Volume 5, Issue
2
May 2003
Insert
May 2003
Volume 5, Issue
3
August 2003
Congratulations on fifth year
Congratulations on fifth year
Suffering, healing and the wounded healer
More fifth year congratulations
Advance care planning – update and practical tips
Historical Vignette – A century of radiation therapy in Canada
Research Corner
Dr. Carol Sawka
Dr. Peeter Poldre
Dr. Mary Vachon
Dr. Shun Wong
Dr. Scott Berry
Dr. Charles Hayter
Dr. Rebecca Wong
Pain in cancer: The CARE approach
Dr. Larry Librach
From the guest editor’s desk
The role of the social worker in palliative oncology
Reflections on anxiety in confronting advanced cancer
Historical Vignette – Spring fever
Research Corner
Dr. Charles Hayter and Ms. Lou Andersson
Ms. Magdalene Winterhoff
Dr. Mary Vachon
Dr. Charles Hayter
Dr. Rebecca Wong
Advances and challenges in the management of febrile neutropenia
Dr. Elizabeth J. Phillips
Supported by Amgen Canada Inc.
From the guest editor’s desk
Lymphoma in the elderly
Demorarlization in persons with advanced cancer
Dr. Toni Barnes
Dr. Tom Kouroukis
Dr. Mary Vachon
33
CONTENT OF PREVIOUS ISSUES AND INSERTS OF HOT SPOT
Insert
August 2003
Volume 5, Issue
4
November 2003
Insert
November 2003
Volume 6, Issue
1
February 2004
Insert
Ethical issues in dealing with demands for “futile” treatment
Historical Vignette – The history of oxygen therapy
Research Corner
Dr. Scott Berry
Dr. Charles Hayter
Dr. Rebecca Wong
Advances for end-of-life respiratory care
Dr. Chin K. Chung
Supported by Vital Aire
From the guest editor’s desk
Referral of patients to the rapid response radiotherapy clinic
Boredom in terminal illness
Hot Spot Survey 2003
“No CPR” – Talking it over
Historical Vignette – The Radium Institute of Toronto
Research Corner
Dr. Cyril Danjoux
Dr. Mary Vachon
Dr. Scott Berry
Dr. Charles Hayter
Dr. Andrea Bezjak
Androgen ablation for metastatic prostate cancer
Dr. Richard Choo
Supported by Aventis
From the guest editor’s desk
Brain metastases: The magnitude of the problem and the struggle to improve
outcomes
Dignity-conserving care in palliative care
When capacity fluctuates, what happens to consent?
Historical Vignette: The Montreal Neurological Institute
Research Corner
Dr. May Tsao
Palliation in patients with metastatic cancer to the brain
Dr. May Tsao
Dr. May Tsao
Dr. Mary Vachon
Ms. Karen Faith
Dr. Charles Hayter
Dr. Alina Sturdza and Dr. Andrea Bezjak
34
CONTENT OF PREVIOUS ISSUES AND INSERTS OF HOT SPOT
February 2004
Management of brain metastases
Supported by Aventis
May 2004
From the guest editor’s desk
Bisphosphonates in cancer
Anger in the person with advanced disease
Ethics and SARS: Collateral damage and relationships in health care
Historical Vignette: Dr. Herbert Bruce: Ontario cancer visionary
Research Corner
Dr. Charles Hayter
Dr. Rebecca Wong
Dr. Mary Vachon
Ms. Karen Faith
Dr. Charles Hayter
Dr. Jackson Wu & Dr. Edward Chow
Insert
May 2004
Use of bisphosphonates in men with hormone refractory prostate cancer
Use of bisphosphonates in women with breast cancer
Dr. Scott Berry
Dr. Mark Clemons
From the guest editor’s desk
Supportive Care in Cancer Symposium
Forgiveness in palliative care
Making decisions for others
Survey shows 40% of RRRP patients arrive with missing info: A plea for help
Research Corner
Dr. Cyril Danjoux
Dr. Cyril Danjoux
Dr. Mary Vachon
Ms. Karen Faith
Dr. Charles Hayter & Ruth Connolly
Dr. Laura Dawson
Insert
August 2004
Rapid Response Radiotherapy Program (RRRP) Review 1996-2003
RRRP Referral Form
Dr. C. Danjoux
Volume 6,
Issue4
November 2004
From the guest editor’s desk
Dr. Edward Chow
The effect of SARS on access to palliative radiotherapy in the RRRP
Dr. Justin Lee, L. Holden, K. Fung, C.
Volume 6,
Issue2
Volume 6,
Issue3
August 2004
35
CONTENT OF PREVIOUS ISSUES AND INSERTS OF HOT SPOT
Insert
November 2004
Reflections on the life and death of Mary Peacock
Quality end-of-life care: Role of economics and the moral climate
Historical Vignette: The Canadian Society for the History of Medicine
Research Corner
Danjoux, E. Chow, C. Gillies
Dr. Mary Vachon
Ms. Karen Faith
Dr. Charles Hayter
Dr. Jackson Wu & Dr. Edward Chow
Cannabinoids in medical practice
Dr. Vincent Maida
36