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1 SCIENTIFIC PROGRAMM Monday, September 23, 2013 10.00 – 2.00 Registration at Evangelische Akademie Tutzing SET UP POSTERS 12.30 2.00 LUNCH THOMAS C. G. BOSCH AND THOMAS W. HOLSTEIN Welcome to “Unravelling the Developmental Regulatory Network in Early Animals” PHYLOGENOMICS AND ANCESTRAL GENOMES (CHAIR: ROBERT E. STEELE, Irvine) 2.15 Bornberg-Bauer, Erich (Münster) Our deprived genomes: still alive and signalling 2.35 Simion, Paul (Paris) Reconstructing phylogenetic relationships within ctenophores and cnidarians : new data and new methods 2.50 Adamski, Marcin (Bergen) Surprisingly complex developmental toolkits of calcisponges 3.05 COFFEE LIFE CYCLE EVOLUTION (CHAIR: EVELYN HOULISTON, Ville Franche) 3.35 Wei Wang (Kiel) Regulation of metamorphosis and the evolution of life cycles: insights from the common moon jelly Aurelia aurita 3.50 Kraus, Johanna (Vienna) Relationship of polyp and medusa body plan: implications for cnidarian life cycle evolution 2 4.05 Kraus, Yulia (Moscow) The unusual development of Hydractinia 4.20 Cartwright, Paulyn (Kansas) Wnt pathway expression and the evolution of medusae reduction in Hydrozoa 4.35 Sanders, Steven (Kansas) An RNA-seq approach to investigate the evolution and development of polyp polymorphism in Hydractinia symbiolongicarpus 4.50 Reyes, Alejandro (Okinawa) Tissue morphogenesis and homeostasis in scleractinian corals: cellular plasticity at the base of metazoan life. 5.05 Levy, Oren (Bar Ilan) The mystery of synchronising mass spawning events 5.25 RELAX AND ENJOY THE PARK 7.00 DINNER EVENING SESSION I SPONGE DEVELOPMENTAL BIOLOGY (CHAIR: MONIKA HASSEL, Marburg) 8.30 Adamska, Maja (Bergen) Developmental gene expression indicates homology of poriferan and eumetazoan body plans 8.50 Funayama, Noriko (Kyoto) How do sponges build up the spiculous skeleton ? 9.10 Alié, Alexandre (Kyoto) The ancestral gene toolkit of metazoan stem cells 9.25 KNOW ABOUT EACH OTHER IN THE BAR 3 Tuesday, September 24, 2013 DEVELOPMENTAL REGULATORY NETWORKS (I) (CHAIR: BERT HOBMAYER, INNSBRUCK) 8.30 Houliston, Evelyn (Villefranche) A fresh view of the metazoan developmental regulatory gene toolbox from transcriptome analysis in Clytia embryos 8.50 Hassel, Monika (Marburg) FGFR signaling in Hydra: a network controls morphogenesis and neural differentiation. 9.10 Böttger, Angelika (Munich) Creating boundaries in hydra involves notch-signalling 9.30 Manuel, Michael (Paris) Wnt/ß-catenin signalling in an adult Ctenophore 9.50 López Quintero, Javier (Kiel) How to make a border in Hydra. Analysing position-dependent gene expression in vivo 10.05 Gufler, Sabine (Innsbruck) Characterization of wnt/beta-catenin target genes in cnidarian axis formation and regeneration 10.20 COFFEE DEVELOPMENTAL REGULATORY NETWORKS (II) (CHAIR: ULI TECHNAU, Vienna) 10.50 Gibson, Matt (Kansas) Tentacle development in Nematostella: cellular mechanisms and developmental patterns 11.10 Technau, Ulrich (Vienna) Identification of brachyury target genes in Nematostella vectensis 11.30 Fajardo Castro, Rossy Johana (Bogota) Characterization of a trefoil factor (tff) gene involved in epithelial repair in the cnidarian model Hydractinia symbiolongicarpus 11.45 Dattoli, Anna Ada (Amsterdam) Characterization of the sea anemone transcription factors snail 4 12.00 Ikmi, Aissam (Kansas) Functional evolution of the yap/yorkie proto-oncogene and elucidation of its core transcriptional program 12.15 RELAX AND ENJOY THE PARK 12.30 LUNCH PATTERN FORMATION AND BODY AXIS EVOLUTION (I) (CHAIR: DAVID MILLER, Townsville) 2.00 Holstein, Thomas (Heidelberg) The hydra organizer and the evolution of metazoan body axes 2.20 Steinmetz, Patrick (Vienna) Ectodermal digestive gland cells in the sea anemone Nematostella vectensis challenge the common origin of cnidarian and bilaterian endoderm 2.35 Rentzsch, Fabian (Bergen) Interaction of six3/6 and canonical wnt signalling in the patterning of the oral-aboral axis of Nematostella vectensis 2.50 Watanabe, Hiroshi (Heidelberg) Asymmetric neural patterning of the sea anemone Nematostella vectensis 3.05 COFFEE PATTERN FORMATION AND BODY AXIS EVOLUTION (II) (CHAIR: MAJA ADAMSKA, BERGEN) 3.35 Özbek, Suat (Heidelberg) The making of tubes: the cnidarian solution 3.50 Leclère, Lucas (Bergen) Bilateral symmetry in the sea anemone Nematostella vectensis is regulated by the BMP co-receptor repulsive guidance molecule 4.05 Genikhovich, Grigory (Vienna) Molecular mechanism for specification and maintenance of the directive axis in Nematostella vectensis 5 4.20 Momose, Tsuyoshi (Villefranche) Efficient gene knock-out by talen and its application; how planar cell polarity is coordinated to body axis? 4.35 Röttinger, Eric (Nice) Etsa1 is required for gastrulation movements and specification of the central domain within the cnidarian gene regulatory network MODEL-BASED APPROACHES (CHAIR: MATT GIBSON, Kansas) 4.50 Meinhardt, Hans (Tübingen) Pattern formation in hydra and planarians: modeling reveals similarities and differences 5.10 Kaandorp, Jaap (Amsterdam) A model-based approach for inferring a gene regulatory network for the developing Nematostella vectensis gut 5.30 RELAX AND ENJOY THE PARK 7.00 DINNER EVENING SESSION II INVITED LECTURE (CHAIR: THOMAS C.G. BOSCH, Kiel) 8.30 9.30 Gilbert, Scott F. (Swarthmore/Helsinki) We were never individuals: symbiosis as the way of animal life KNOW ABOUT EACH OTHER IN THE BAR 6 Wednesday, September 25, 2013 THE CNIDARIAN HOLOBIONT: HOST-SYMBIONT INTERACTIONS (CHAIR: NORIKO FUNAYAMA, Kyoto) 8.30 Bosch, Thomas (Kiel) Coupling developmental pathways to the environment 8.50 Guse, Annika (Heidelberg) Dissecting the molecular basis of cnidarian-dinoflagellate-endosymbiosis using Aiptasia as a model system 9.05 Fraune, Sebastian (Kiel) Distinct antimicrobial peptide expression determines host species-specific bacterial associations 9.20 Grasis, Juris (Kiel, San Diego) Species-specific viromes in the ancestral holobiont Hydra 9.35 Hamada, Mayuko (Kiel, Okinawa) The Hydra viridissima / Chlorella symbiosis revisited: understanding a complex team of players at the base of animal evolution 9.50 Pernice, Mathieu (Lausanne) From single cell to ecosystem: understanding how the biology of elements sustains Cnidariadinoflagellate symbiosis 10.05 Voolstra, Christian Robert (Thuwal, KAUST) Effect of gene transfer agents on bacterial gene expression and coral larvae 10.20 COFFEE 7 ALLORECOGNITION AND STRESS RESPONSE (CHAIR: MAJA ADAMSKA, Bergen) 10.50 Nicotra, Matthew (Pitsburgh) Molecular mechanisms of allorecognition specificity in Hydractinia symbiolongicarpus 11.10 Miller, David (Townsville) Studying the transcriptional response of Acropora millepora to stress using high-throughput sequencing 11.30 Zarate-potes, Alejandra (Bogota) The Hydractinia symbiolongicarpus immunotranscriptome 11.45 Ocampo-Ibañez, Ivan Dario (Bogota) The immune-transcriptome of caribbean reef-building coral Diploria strigosa 12.00 RELAX AND ENJOY THE PARK 12.30 LUNCH EPIGENETIC REGULATION (CHAIR: YASHODA GHANEKAR, Bangalore) 2.00 Foret, Sylvain (Canberra) DNA methylation in the coral Acropora millepora 2.20 Galande, Sanjeev (Pune) Identification and functional characterization of histones and their variants in Hydra: insights into dynamic epigenetic regulation 8 HYDRA IN TRANSLATIONAL RESEARCH (CHAIR: ANGELA BÖTTGER, Munich) 2.35 Ambrosone, Alfredo (Pozzuoli) Gold nanoparticle journey in Hydra: ultrastructural analysis of entrance, intracellular trafficking and clearance 2.50 Tortiglione, Claudia (Pozzuoli) Nanoparticle-mediated remote control of hyperthermia in an invertebrate model 3.05 5.00 – 8.00 8.00 – 10.00 COFFEE BOAT EXCURSION AND BAVARIAN BUFFET ON STARNBERGER SEE POSTER PRESENTATIONS (WITH WINE AND BEER) GENES AND DEVELOPMENT (G) SENSORY AND NERVOUS SYSTEMS (N) SYMBIOSIS AND ALLORECOGNITION (S) ENVIRONMENTAL INTERACTIONS (E) METAMORPHOSIS (M) CELLULAR DIFFERENTIATION (C) 9 Thursday, September 26, 2013 STEM CELLS AND PRECURSOR DIFFERENTIATION IN HYDROZOANS (CHAIR: RICARDO BENAVENTE, Würzburg) 8.30 Domazet- Lošo, Tomislav (Zagreb) Tracing the origin of tumor cells 8.45 Ghanekar, Yashoda (Bangalore) Quiescent stem cells in Hydra 9.00 Bradshaw, Brian (Galway) Stem cell mediated regeneration in the cnidarian Hydractinia 9.15 Fraune, Johanna (Würzburg) The single nuclear lamin of Hydra: a role in polyp proliferation and senescence? 9.30 COFFEE 10.00 Juliano, Celina (New Haven) Uncovering the conserved stem cell functions of the piwi/pirna pathway in Hydra 10.15 Klimovich, Alexander (Kiel) The interstitial stem cell niche in Hydra 10.30 Richards, Gemma Aian (Bergen) The development of neurons and nematocytes from a pool of neural progenitor cells in Nematostella is controlled by opposing roles of notch signaling and a soxb gene 10 EVOLUTION OF THE NERVOUS SYSTEM (CHAIR: GABY KASS-SIMON, Kingston) 10.45 Schueler, Andreas (Münster) How hydra got the touch - the evolution of the nompc gene family and its implications for mechanosensation in Cnidaria 11.00 Mason, Benjamin Matthew (Townsville) Evidence for multiple opsin phototransduction pathways in larvae of a reef-building coral 11.15 Shimizu, Hiroshi (Mishima) Is there a brain in Hydra? 11.30 POSTER PRIZE AWARDS GENERAL DISCUSSION AND CONCLUDING REMARKS Take down posters! 12.30 LUNCH DEPARTURE