Survey
* Your assessment is very important for improving the workof artificial intelligence, which forms the content of this project
Download Cyanide Antidotes What is a safe cyanide poisoning antidote as it
Transcript
FAQ Cyanide Antidotes What is a safe cyanide poisoning antidote as it relates to smoke inhalation? What cyanide antidotes are approved by the FDA for cyanide poisoning? Is this antidote approved by the FDA for use on smoke inhalation victims? Is more than one drug contained in the packaging for this antidote? If so, what drugs? Can this antidote be used for industrial exposure to cyanide poisoning if CO is not a consideration? Can this antidote be used for cyanide poisoning as it relates to fire smoke exposure – when carbon Not harmful to patients with concurrent carbon monoxide poisoning. Quick and easy to administer. Not dangerous to patients who ultimately are found NOT to be suffering from cyanide poisoning Cyanokit/ Hydroxocobalamin Cyanide Antidote Kit (CAK), a/k/a Lilly Kit, Pasadena Kit, Keystone Kit Nithiodote Cyanokit / Hydroxocobalamin Yes Cyanide Antidote Kit Nithiodote No Yes Yes Cyanokit 5 g consists of 2 vials, each with 2.5 g lyophilized Hydroxocobalamin dark red crystalline powder for injection. After reconstitution, each vial contains hydroxocobalamin for injection, 25 mg/mL Yes Yes 2- 10mL Ampules of Sodium Nitrite 300mg in 2mL 2- 50mL Vials of Sodium Thiosulfate 12.5g in 50mL 12- Ampules of Amyl Nitrite Inhalant, 5 min (0.3mL) 1- Sterile 10mL Syringe with Needle 1- Stomach Tube 1- Sterile 60mL Syringe 1- Sterile Needle 1- Non-sterile 60mL Syringe 1- Tourniquet Instructions for the treatment of Cyanide poisoning. Yes Sodium Nitrite - 10 mL Sodium Thiosulfate - 50 mL Yes Yes Yes The entire kit should not be administered to a smoke The entire kit should not be monoxide exposure is also a consideration? Are all of the drugs in this kit safe for administration to a smoke inhalation patient? Which drug could be dangerous to a smoke inhalation a patient? Why or how could Nitrites be dangerous to a smoke inhalation victim? inhalation victim. Yes No administered to a smoke inhalation victim. No N/A Sodium Nitrite Sodium Nitrite N/A The nitrites enable the red blood cells to absorb cyanide out of the blood stream and out the body’s cells and transport it to the liver, where sodium thiosulfate transforms it into far less toxic substance that is excreted through the kidneys into urine and passed out of the body. With red blood cells transporting cyanide, there are fewer seats for oxygen to make the journey from the lungs to the rest of the body’s cells. And in the presence of carbon monoxide, there’s even far less room for the oxygen within the red blood cells. So even though the nitrites are pulling cyanide out of the cells, which would allow energy production to resume, not enough oxygen reaches the cells to fuel the process. Also, sodium nitrite is a vasodilator which can cause the blood vessels to increase in diameter, which drops the blood pressure. Since victims of cyanide poisoning are already hypotensive, meaning having low blood pressure, if sodium nitrite is delivered too rapidly, it can dilate the blood vessels making hypotension even worse. Same explanation for Cyanide Antidote Kit.
