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piperacillin-and-tazobactam-monograph
piperacillin-and-tazobactam-monograph

... In general, dose selection for an elderly patient should be approached with caution, usually starting at the low end of the dosing range, reflecting the greater frequency of decreased hepatic, renal, or cardiac function, and of concomitant disease or other drug therapy. Piperacillin and Tazobactam f ...
2012 Fluoride Therapy Guide
2012 Fluoride Therapy Guide

... Potential adverse reproductive effects of fluoride exposure in humans has not been adequately evaluated. Adverse effects on reproduction were reported for rats, demonstrated that lower concentrations of fluoride (5 mg/kg of body weight) did not result in impaired fertility and reproductive capabilit ...
FREE BONUS offer! - Colgate Professional
FREE BONUS offer! - Colgate Professional

... weight. In a second study, no carcinogenesis was observed in rats, males or females, treated with fluoride up to 11.3 mg/kg of body weight. Epidemiological data provide no credible evidence for an association between fluoride, either naturally occurring or added to drinking water, and risk of human ...
Ampicillin
Ampicillin

... Ampicillin is relatively resistant to inactivation by gastric acid and is moderately well absorbed from the gastrointestinal tract after oral doses. Food can interfere with the absorption of ampicillin so doses should preferably be taken at least 30 minutes before meals. Peak concentrations in plasm ...
Martindale: The Complete Drug Reference
Martindale: The Complete Drug Reference

... 1. 1. Shultz S, et al. Diclofenac poisoning is widespread in declining vulture populations across the Indian subcontinent. Proc Biol Sci 2004; 271 (suppl 6): S458–S460. PubMed 2. 2. Sharp D. Meloxicam to prevent rabies? Lancet 2006; 367: 887–8. PubMed ...
Unveiling the compatibility of eugenol with formulation excipients by
Unveiling the compatibility of eugenol with formulation excipients by

... Carbopol 940, chitosan, sodium alginate, and polycaprolactone (PCL) for their possible use in the formulation of eugenol loaded nanoemulsion gels and nanoparticles. Methods: The eugenol-excipient compatibility studies were carried out by visual observations, differential scanning calorimetry (DSC), ...
product monograph - Takeda Canada Inc.
product monograph - Takeda Canada Inc.

... was increased in patients who received high-dose, defined as multiple daily doses, and longterm PPI therapy (a year or longer). Patients should use the lowest dose and shortest duration of PPI therapy appropriate to the condition being treated. Patients at risk for osteoporosisrelated fractures shou ...
Blind copy - Open Journal Systems
Blind copy - Open Journal Systems

... The efavirenz raw material was previously characterized before and controlled during the compatibility studies. The result obtained of efavirenz by DSC was in agreement with the literature, to the Form I, which cites a melting point of about 411 – 413 K (16). Figure 1 shows the x-ray diffraction pat ...
Full Text
Full Text

... Figure 1. Locomotion assay to identify drugs that rescue the scn1Lab mutant epilepsy phenotype. a, Schematic of the phenotypebased screening process. Chemical libraries can be coded and aliquoted in small volumes (75 ␮L) into individual wells containing one mutant fish. The 96-well microplate is arr ...
A REVIEW ON ANALYTICAL METHODOLOGIES FOR THE DETERMINATION OF PIPERACILLIN
A REVIEW ON ANALYTICAL METHODOLOGIES FOR THE DETERMINATION OF PIPERACILLIN

... penicillinate sulfone, structurally related to sulbactam being a betalactamase inhibitor; it is synergistic with many beta-lactamase liable drugs such as penicillins and cephalosporins1-2. Piperacillin is not absorbed orally, and must therefore be given by intravenous or intramuscular injection; pip ...
Preparation and Evaluation of Soft Gellan Gum Gel Containing
Preparation and Evaluation of Soft Gellan Gum Gel Containing

... and they were told to keep the gel in mouth for 5 sec. The volunteers were instructed not to swallow the gel. An interval of 0.5 h was kept for the volunteers between the taste evaluations of both the samples. The volunteers were asked to comment on the bitterness, aftertaste, sweetness and flavor o ...
Martindale: The Complete Drug Reference
Martindale: The Complete Drug Reference

... By injection the usual dose is 750 mg of cefuroxime every 8 hours but in more severe infections 1.5 g may be given intravenously every 8, or in some cases every 6 hours. Those with pneumonia or with acute exacerbations of chronic bronchitis may respond to sequential therapy with parenteral cefuroxim ...
Evaluation of Diuretic activities of hydro
Evaluation of Diuretic activities of hydro

... The kidneys receive about a quarter of the cardiac output. From the several hundred litres of plasma that flow through them each day, they filter (in a 70-kg human) approximately 120 litres per day, 11 times the total extracellular fluid volume. This filtrate is similar to plasma apart from the abs ...
PRODUCT MONOGRAPH CEFAZOLIN FOR INJECTION 500 mg, 1
PRODUCT MONOGRAPH CEFAZOLIN FOR INJECTION 500 mg, 1

... There are instances of patients who have had reactions to both penicillins and cephalosporins (including fatal anaphylaxis after parenteral use). Clinical and laboratory evidence of partial cross-allergenicity of the two drug classes exists. Cefazolin sodium should be administered cautiously and the ...
`bis (L-glutamine) potassium nitrate` crystal
`bis (L-glutamine) potassium nitrate` crystal

... taken in water ~15 ml and was stirred well to obtain a clear colorless solution (pH~5.5). H 2O2 (2 ml) was added to this and the reaction mixture was left undisturbed at ambient temperature. Slow evaporation of the solvent resulted in the separation of crystals in ~7 days, which were isolated by fil ...
product monograph - Takeda Canada Inc.
product monograph - Takeda Canada Inc.

... Short-term and long-term treatment with pantoprazole sodium in a limited number of patients up to 6 years have not resulted in any significant pathological changes in gastric oxyntic exocrine cells. Endocrine and Metabolism Hypomagnesemia Hypomagnesemia, symptomatic and asymptomatic, has been report ...
MAXIDOL® Liquid Gels
MAXIDOL® Liquid Gels

... Adults (12-65 years): 1 caplet/capsule every 8 - 12 hours. For individuals over 65 years, 1 capsule every 12 hours. Do not take more than 2 capsules in a 24 hour period. Drink a full glass of water with each dose. Under 12 years: Children under 12 should not take this drug. The safety in pediatric u ...
Formulation, Characterization and Physicochemical Evaluation of
Formulation, Characterization and Physicochemical Evaluation of

... organic acids such as citric and tartaric acid.1 Generally, these tablets are included drugs that are solved rapidly when entered to water and they are recommended as a clear and palatable solution.2 So, they can be prescribed to patients who suffered from swallow capsules or tablets.3The main advan ...
Stability and viscosity of a flavored omeprazole oral suspension for
Stability and viscosity of a flavored omeprazole oral suspension for

... oral suspension (omeprazole–sodium bicarbonate) during refrigerator and room temperature storage were investigated. Methods. Omeprazole–sodium bicarbonate 20-mg packets were suspended to initial omeprazole concentrations of 0.6 and 2 mg/mL, and omeprazole–sodium bicarbonate 40-mg packets were suspen ...
August  II,2000 VIA  Fax:  301.8275562 and  Fed-Ex Attention:
August II,2000 VIA Fax: 301.8275562 and Fed-Ex Attention:

... Procedure: A standardized procedure for inhalation has been developed. The challenge is performed by giving a subject ascending serial concentrations of Provocholine@ (methacholine chloride powder for inhalation). At each concentration, five breaths are administered by a nebulizer that permits inter ...
Clindamycin in 0.9% Sodium Chloride Injection
Clindamycin in 0.9% Sodium Chloride Injection

... with severe colitis which may end fatally, it should be reserved for serious infections where less toxic antimicrobial agents are inappropriate [see Indications and Usage (1)]. It should not be used in patients with nonbacterial infections such as most upper respiratory tract infections. C. difficil ...
PRODUCT MONOGRAPH PRIMAXIN® (imipenem and cilastatin
PRODUCT MONOGRAPH PRIMAXIN® (imipenem and cilastatin

... Concomitant administration of PRIMAXIN® and probenecid results in only minimal increases in plasma levels of imipenem and plasma half-life. It is not recommended that probenecid be given with PRIMAXIN®. PRIMAXIN® should not be mixed with or physically added to other antibiotics. PRIMAXIN® has been a ...
Furosemide - Circulation
Furosemide - Circulation

... where they were given a diet of constant composition. Metabolic ward techniques and analytic procedures for blood and urine have been reported previously.15 In the balance studies patients had been on a constant diet for at least 4 days prior to administration of diuretics. In evaluation of the effi ...
Multiple-choice questions : 1. Which of the following solutions
Multiple-choice questions : 1. Which of the following solutions

... No. of moles of NaOH in a bottle of the oven cleaner = 0.399  2 mol = 0.798 mol Molar mass of NaOH = 23.0 + 16.0 + 1.0 = 40.0 g mol1 Mass of NaOH = 0.798  40.0 = 31.9 g [1] The oven cleaner contains 31.9 g of sodium hydroxide. ...
Analysis of Monoclonal Antibody and Related Substances using a
Analysis of Monoclonal Antibody and Related Substances using a

... salting-out agent, which at high salt concentration, retains the protein by increasing hydrophobic interaction between the protein and the stationary phase. HIC has been widely used as an orthogonal method to size exclusion chromatography and ion exchange chromatography for analysis of mAb and relat ...
1 2 3 4 5 ... 16 >

Sodium

Sodium /ˈsoʊdiəm/ is a chemical element with symbol Na (from New Latin natrium) and atomic number 11. It is a soft, silver-white, highly reactive metal. In the Periodic table it is in column 1 (alkali metals), and shares with the other six elements in that column that it has a single electron in its outer shell, which it readily donates, creating a positively charged atom - a cation. Its only stable isotope is 23Na. The free metal does not occur in nature, but instead must be prepared from its compounds. Sodium is the sixth most abundant element in the Earth's crust, and exists in numerous minerals such as feldspars, sodalite and rock salt (NaCl). Many salts of sodium are highly water-soluble: sodium ions have been leached by the action of water from the earth's minerals over eons, so that sodium (and chlorine) are the most common dissolved elements by weight in the oceans.Sodium was first isolated by Humphry Davy in 1807 by the electrolysis of sodium hydroxide. Many sodium compounds are useful, such as sodium hydroxide (lye) for soap-making and sodium chloride for use as a de-icing agent and a nutrient (edible salt).Sodium is an essential element for all animals and some plants. Sodium ions are the major cation in the extracellular fluid (ECF) and as such are the major contributor to the ECF osmotic pressure, and thus ECF compartment volume. Loss of only water from the ECF compartment increases the sodium concentration: hypernatremia. Isotonic loss of water and sodium from the ECF compartment decreases the size of that compartment: ECF hypovolemia.Sodium ions are pumped out of cells by Na+/K+-ATPase in exchange for potassium. It pumps three sodium ions out of the cell for every two potassium ions pumped in, contributing to the fact that about forty times as much potassium is inside cells compared to outside, and about ten times as much sodium is outside cells compared to inside. In nerve cells, a buildup of electrical charge across the cell membrane allows transmission of a nerve impulse - an action potential - when the charge is dissipated.
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