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Editöre Mektuplar / Letters to the Editor
Treatment of Mental Disorders in
Problematic Cases Due to a Nuclear Plant
Crisis: A Topic in Clinical
Psychopharmacology
Viroj Wiwanitkit
Sir, the topic of the present problematic Fukushima
nuclear plant crisis is of interest. Mental disorders are
important clinical problems in patients exposed to
radionuclides in the nuclear plant crisis. The treatment of
these cases is interesting. Referring to previous publications
on a similar nuclear plant crisis, the Chernobyl crisis, a
complexity in treatment can be seen. Several drugs
including gidazepam and piracetam can be used.
Neznamov et al. noted that “administration of
gidazepam--an atypical benzodiazepine tranquilizer--in
combination with piracetam produces correction of the
undesired stimulant action of the latter drug, while
DOI: 10.5455/bcp.20111202114549
potentiating the nootropic (antiamnesic) and anxiolytic
effects (1).” The concern about the co-presentation of
brain pathology in patients with mental disorders due to a
nuclear crisis should also be addressed (2,3). For those
cases, Otroshchenko noted that “Protiadenum combined
with nootropil and those drugs improving cerebral
microcirculation (cavintonum) enhance efficiency of
psychopharmacotherapy of depressive disorders in persons
with organic infliction of brain (2).”
Corresponding author:
Professor Viroj Wiwanitkit
Wiwanitkit House, Bangkhae, Bangkok Thailand 10160
Email: [email protected]
Phone: 6624132436
This letter was accepted for publication in November 10,
2011.
References:
1. Neznamov GG, Koshelev VV, Voronina TA, Trofimov SS.
Experimental and clinical rationale for complex treatment of mental
disorders in clean-up workers of the Chernobyl nuclear plant
accident. Eksp Klin Farmakol 2002;65(2):12-6.
3. Rymsha SV, Chernachuk SV. Therapy of mental disorders in
Chernobyl accident victims with dyscirculatory encephalopathy of
mixed genesis (practical considerations)]. Zh Nevrol Psikhiatr Im S
S Korsakova 2000;100(7):50-1.
2. Otroshchenko NP. Psychopharmacotherapy in combine treatment
of depressive disorders in patients with brain pathology affected by
the Chernobyl Atomic Electric Power Station accident. Lik Sprava
2000;(6):8-10.
Klinik Psikofarmakoloji Bülteni, Cilt: 22, Sayı: 1, 2012 / Bulletin of Clinical Psychopharmacology, Vol: 22, N.: 1, 2012 - www.psikofarmakoloji.org
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