Download STUDI PENGGUNAAN OBAT PADA PASIEN GASTRITIS EROSIVA

ADLN - Perpustakaan Universitas Airlangga
STUDI PENGGUNAAN OBAT PADA PASIEN GASTRITIS EROSIVA (Penelitian
Dilakukan di Instalasi Rawat Inap Medik RSUD Dr. Soetomo Surabaya)
RAHMA NOOR FAUZIAH
dr. Titong Sugihartono, Sp.PD.,K-GEH
KKB KK FF 312 11 Fau s
ABSTRACT
Erosive gastritis is a disease of gastric mucosal erosion due to an impaired mucosal
defense. Patients with erosive gastritis require proper care to achieve optimal outcome.
The purpose of the present study was to identify and analyze drug use in patients with
erosive gastritis. Research was carried out prospectively from March to May 2011 at the
Inpatient Wards of Dr. Soetomo Hospital of Surabaya. Data was analyzed descriptively.
Of the 26 patients with erosive gastritis enrolled in this study, the major etiology were
consumption of herbs (42.31%) and use of NSAIDs (30.77%). Clinical/laboratory data
indicated that those patients experienced melena (84.62%), anemia (80.77%),
hematemesis (50.00%), nausea (34.62%), and abdominal pain (34.62%). Drugs used in
the therapy of erosive gastritis were PPI class, ARH2 class, sucralfate, and antacids.
Patients received therapy in single form or in combination. The most widely used monotherapy was from PPI classes, i.e omeprazole i.v. 1-2 dd 40 mg. While the most widely
used combination therapy was a combination of omeprazole i.v. 2 dd 40 mg and
sucralfate p.o. i.v. 3-4 dd 15-30 mL. Intravenous route was the most frequently used
initial route of therapy. The duration therapy of PPI classes is 3-21 days. Drug-related
problems occurring in the study included an improper combination of omeprazole and
ranitidine and potential interaction of omeprazole with clopidogrel.
Keyword: Drug Utilization Study, Erosive Gastritis, Proton Pump Inhibitor, Stress
Related Mucosal Disease
Skripsi
Studi penggunaan obat ...
Rahma Noor Fauziah