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Transcript
Manufacturers of
Hypo-allergenic
Nutritional
Supplements
Hyaluronic
Acid
What Is It?
What Is The Source?
Hyaluronic acid, or HA, is a naturally occurring polymer
found in every tissue of the body. It is particularly
concentrated in the skin (almost 50% of all HA in the body
is found in the skin) and synovial fluid. It is composed
of alternating units of n-acetyl-d-glucosamine and
d-glucuronate. This polymer's functions include attracting
and retaining water in the extracellular matrix of tissues,
in layers of skin, and in synovial fluid.*
The source of Pure Encapsulations Hyaluronic acid is
rooster comb. Hypo-allergenic plant fiber is derived from
pine cellulose.
Features Include
Are There Any Potential Side Effects Or
Precautions?
Easily Absorbed: In nature, HA is a large molecular
weight compound, ranging in size from 500,000-6,000,000
daltons. This is too large to be absorbed in the small
intestines. Pure Encapsulations HA has undergone a
sophisticated, patent-pending enzymatic process that
alters the molecular weight, though not chemical
composition. The final result is an easily absorbed HA
polymer with a molecular weight of 5,000 daltons.
Preliminary Research: Subjective evaluations conducted by
scientists at a Japanese university involved 96 individuals.
The reports suggest an enhancement of skin and joint
health using low molecular weight HA. A number of
anecdotal and preliminary results also indicate a positive
effect on skin and joint health.*
Uses For Hyaluronic Acid
Skin Health: For skin cells, the ability of HA to attract
and retain water is essential for proper cell-to-cell
communication, hydration, nutrient delivery, and waste
and toxin elimination. HA also appears to support the
skin by promoting healthy turnover and renewal
of keratinocytes, moderating the appearance of fine lines
and age spots.*
Recommendations
Pure Encapsulations recommends taking 6 capsules per
day (providing 37.8 mg HA), in divided doses, with or
between meals.
At this time, there are no known side effects or precautions.
If pregnant or lactating, consult your physician before taking
this product.
Are There Any Potential Drug Interactions?
At this time, there are no known adverse reactions when
taken in conjunction with medications.
References:
1. Sakai S, Yasuda R, Sayo T, Ishikawa O, Inoue S. Hyaluronan exists in the
normal stratum corneum. J Invest Dermatol 2000 Jun;114(6):1184-7.
2. Meyer LJ, Stern R. Age-dependent changes of hyaluronan in human skin.
J Invest Dermatol 1994 Mar;102(3):385-9.
3. Ghersetich I, Lotti T, Campanile G, Grappone C, Dini G. Hyaluronic acid in
cutaneous intrinsic aging. Int J Dermatol 1994 Feb;33(2):119-22.
4. Manna F, Dentini M, Desideri P, De Pita O, Mortilla E, Maras B.
Comparative chemical evaluation of two commercially available derivatives
of hyaluronic acid (hylaform from rooster combs and restylane from streptococcus) used for soft tissue augmentation. J Eur Acad Dermatol Venereol
1999 Nov;13(3):183-92.
(continued)
Joint Health: For joints, HA is especially supportive of
healthy lubrication and shock absorption. Furthermore,
in vitro studies indicate that HA modulates prostaglandin
production, providing additional support for joint function.*
*These statements have not been evaluated by the Food & Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
For educational purposes only. Consult your physician for any health problems.
5. Altman RD. Status of hyaluronan supplementation therapy in osteoarthritis. Curr Rheumatol Rep 2003 Feb;5(1):7-14.
6. Omori, Seiji. Panel Study on Injuv (low molecular weight hyaluronic acid).
Otsuma Universtiy, Japan, 2000.
7. Healthnotes Clinical Essentials. Copyright 2004. Healthnotes, Inc.
Hyaluronic Acid
e a c h ve g e t a b l e c a p s u l e c o n t a i n s
hyaluronic acid powder (low molecular weight) ...............................70 mg.
(providing a minimum of 9% hyaluronic acid)
(hypo-allergenic plant fiber added to complete capsule volume requirement)
6 capsules per day, in divided doses, with or between meals.