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For more information on these products contact your local VWR sales office, send an e-mail to [email protected] or visit our website www.vwr.com Cell manipulation Control the power – transfer the genes BTX New Electro Cell Manipulator – the perfect tool for fusion, nuclear transfer and electroporation applications Cell fusion BTX/Harvard Apparatus, a leader in electroporation and electrofusion instruments and accessories, offers the ECM 2001 Electro Cell Manipulator (ETL and CE marked). This instrument is a safe, user-friendly tool for gene transfer, nuclear transfer and cell fusion of a variety of plant, animal and bacterial cells. • AC feature aligns cells and maintains cell membrane compression • Begin fusion cell and membranes using the DC square wave pulse • Cell fusion complete! The advanced functions of the ECM2001 are ideal for in vivo and in vitro experiments resulting in hybridomas, transfected cancer cells, and engineered embryonic stem cells (ESC), and for in vivo drug delivery and experimental cancer therapy. Nuclear transfer applications until now resulted in low efficiency and low viability. The novel technique employing electrofusion to nuclear-transfer complexes improves both efficiency and viability. In short oocyte-cell couplets are aligned in a BTX fusion chamber by applying AC Model Cat. No. ECM 2001 Embryo Manipulation System ECM 2001 Electro cell Fusion System ECM 2001 Electroporation System ECM 2001 Generator only 732-0615 732-0616 732-0802 732-0617 pulse. The fusion of the couplets is accomplished by applying two DC pulses, and a post-fusion AC pulse. A variety of electrodes incorporated in cuvettes and microslides are available for single cell experimentation, and genetrodes, tweezertrodes and genepaddles for in vivo tests on tissues and organs. The instrument’s CE mark and ETL mark allows it to be a truly global instrument applicable for experimental work around the world. The superior design carries a two year warranty from the day of purchase. BTX’s global technical support team will assist scientists worldwide to optimise their applications and choose the best accessories for their applications. VWR I n t e r n a t i o n a l Issue 17 April 2007 39