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Biology 230 Genetics, Winter Semester 2012 Place and time: Science Building Lecture Hall, Tues, Wed & Fri 10.30-11.20 a.m. Course coordinator and lecturer: Dr. Francis Choy, Cunningham Building Room 062, tel. 721-7107, email: [email protected] Lecturer: Dr. John Taylor, Petch Building Rm 011, tel. 472-4079, email: [email protected] Senior Lab Instructor: Ms. Dawna Brand, Cunningham Rm. 110, Tel.721-7096, email: [email protected] Textbook: Genetics Analysis and Principles by Brooker, 4th (2012) edition, McGraw Hill Publisher. Since the pre- and/or co-requisites for Biol. 230 are Biol. 225 Cell Biology/Biochemistry 299, students are expected to have fundamental knowledge of DNA structure & function, transcription & translation, amino acids, proteins, carbohydrates, and lipids. Method of grade assignment: Laboratory: 30%; lectures: 70% Lecture component - 1st and 2nd midterm examination 15% each; final lecture examination, 40%. Students must pass both the lecture & lab exams by scoring at least an overall 50% in both components, in order to pass the course. Grades: A+ 90100% A 8589.9% A- B+ 8084.9% 7579.9% B 7074.9% B- C+ 6569.9% 6064.9% C 5559.9% D 5054.9% F 049.9% There is NO E grade assigned and subsequently no supplementary exam. Tentative lectures schedule Dr. Choy will cover the eukaryotic cell cycle, mitosis, meiosis, Mendelian genetics and extension, pedigree analysis, non-Mendelian inheritance, cytogenetics, quantitative genetics, biochemical genetics, the Lyon’s hypothesis, & molecular basis of mutations Jan 4, Introduction, chromosomes, and the cell cycle, Ch.1 (general reading), Ch.3, p.44-50 Jan 6 and 10, Reproduction and chromosome transmission, mitosis and meiosis, Ch.3, p.50-63, 66-67 Jan 13, Mendelian inheritance, probability and statistics, Ch.2, p.17-39 Jan 17, 18, Extension of Mendelian inheritance, Ch.4, p.71-94 Jan 20, 24 Cytogenetics – chromosome structure and chromosome aberrations, Ch.8, p.189-215 Jan 25, Guest lecture, Dr. Michelle Steinraths, Medical Genetics Jan. 27, Pedigree analysis and biochemical genetics Jan 31, First mid-term examination Feb 1, 3, Biochemical genetics II; non-Mendelian inheritance, epigenetics and the Lyon’s hypothesis Ch.5, p.103-121 Feb 7 Quantitative genetics, Ch. 25, p. 700-721 Feb 8, 10 Gene mutation and repair, Ch. 16, p.424-453 Feb 13-17, Reading break Dr. John Taylor's lectures begins on Feb 21 and his schedule will be posted on a separate BIOL 230 homepage The 2nd mid-term is scheduled on March 6 2009 and will cover lectures from Feb 1 to March 2.