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International Conference on Cancer Research:
New Horizons
19th-21st November, 2015,
Venue: National Centre for Cell Science, Pune, INDIA
Programme Schedule
Day 1:
19th November, 2015
08.30 am-9.30 am
Registration
9.30 am-10.00 am
Inauguration
Session-I: Cancer Epigenetics & Therapy
Chairs: Dr. D. Mitra & Dr. S. A. Bapat
10.00-10.20 am
I-1: Integration of Epigenetic and Hormone Signaling in Prostate Cancer
Prof. Debabrata Chakravarthi, Northwestern University, USA
10.20-10.40 am
I-2: NPM1 Mediated Induction of p300 Autoacetylation and RNA Pol
II Driven Transcription: Implications in Oral Cancer
Prof. Tapas Kundu, JNCASR, India
10.40-11.00 am:
Tea Break
11.00-11.20 am
I-3: Exploring DNA Double-strand Break Repair for its Role in
Chromosomal Translocations and its Use as a Cancer Therapeutic Target
Dr. Sathees Raghavan, IISc, India
11.20-11.40 am
I-4: Cross-talk between ubiquitylation and phosphorylation mediate the
turnover and mitotic functions of BLM helicase
Dr. Sagar Sengupta, NII, India
11.40-11.55am
S-1: Protein phosphatase 1 regulatory subunit p90 suppresses tumor
growth through inactivation of MAPK pathway and is epigenetically
silenced in feedback loop
Mr. Debashish Paul, NCCS, India
1
Session-II:Cancer Immunobiology & Therapy
Chairs: Dr. G. C. Mishra & Dr. G. Lal
11.55-12.15 pm
I-5: Contribution of MDSC and Tregs to immune suppressive network in
oral cancer
Dr. Shubhada Chiplunkar, ACTREC, India
12.15-12.35 pm
I-6: Intratumoral immune landscape: From immunogenicity to
tolerogenicity
Prof. Gaurishankar Sa, Bose Institute, India
12.35-12.55 pm
I-7: Polypyrimidine tract binding protein 2 is upregulated during CML
disease progression and its deregulation in CML cells efficiently blocks
cell cycle, cell proliferation and promotes apoptosis
Dr. Soumen Chakraborty, ILS, India
12.55-1.10 pm
S-2: Intratumoral natural killer (NK) cells inhibit the differentiation of
effector Th1 cells and promote tumor growth
Mr. Sourav Paul, NCCS, India
1.10-2.10 pm
Lunch Break
Session-III: Mechanism of Tumor Progression & Drug
Resistance
Chairs:Dr. Padma Shastry & Dr. M. K. Bhat
2.10-2.30 pm
I-8: ABC drug transporters and cancer chemotherapy
Dr. Suresh Ambudkar, NCI, USA
2.30-2.50 pm
I-9: Tryptanthrin: A potent anti-melanoma molecule from Wrightia
tinctoria
Dr. Ruby Anto, RGCB, India
2.50-3.05 pm
S-3: Metal based Ayurvedic Nano compounds in cancer therapy: An
Unexplored goldmine for research
Dr. Yogesh Bendale,Rasayu Cancer Clinic, India
3.05-3.20 pm
S-4: AMPK mediated metabolic orchestration and mitochondrial
biogenesis is decisive for cancer cell survival under metabolic stress
Mr. Balkrishna Chaube, NCCS, India
2
3.20-4.50 pm
Tea Break & Poster Presentation (Poster No. P01 to P30)
Session-IV: Stem Cell & Cancer
Chairs: Dr. L. Limaye & Dr. Anjali Shiras
04.50-5.10 pm
I-10: Cancer stem cells and chemo-resistance: An approach towards
targeting ‘cellular plasticity’ in breast tumor
Prof. Tanya Das, Bose Institute,India
5.10-5.30 pm
I-11: Cancer Stem Cells: Link between anchorage-independent growth
and drug resistance
Dr. Annapoorni Rangarajan, IISc, India
5.30-5.45 pm
S-5: Notch1-MAPK Signaling Axis Regulates CD133+ Melanoma
Initiating Cell Growth and Metastasis
Mr. Dhiraj Kumar, NCCS, India
5.45-6.00 pm
S-6: A Tumor Deconstruction Platform Identifies Definitive End Points
in the Evaluation of Drug Responses
Ms. Rutika Naik, NCCS, India
6.15-8.00 pm
Cultural Programme
8.00-10.00 pm
Day-2:
Dinner at NCCS Amphitheater
20th November, 2015
Session-V: Clinical Cancer Research: Therapy and Biomarker
Chairs: Dr. G.C. Kundu & Dr. Srikanth Rapole
9.30-9.50 am
I-12: Precision and Personalized Medicine for Breast Cancer: Challenges
and Opportunities
Dr. Sudeep Gupta, TMH & ACTREC, India
9.50-10.10 am
I-13: "Prognostic markers in breast cancer: is there light at the end of the
tunnel"
Dr. Diptendra Sarkar, IPGME&R and SSKM Hospital, India
3
10.10-10.30 am
I-14: Targetable Alterations in Gynecologic Malignancies – Present and
Future
Dr. Shona Nag, Jehangir Hospital, India
10.30-10.50 am
I-15: Molecular markers in breast cancer and their clinical relevance
Dr. Anupama Mane, Ruby Hall Clinic, India
10.50-11.10 am
Tea Break
11.10-11.30 am
I-16: Clinical Practice in Breast Cancer: Lessons from Molecular Biology
Dr. C. B. Koppiker, Orchids Breast Health Center, India
11.30-11.45 am
S-7: Identification of potential biomarkers in breast cancer using
complementary gel-based and gel-free quantitative proteomic approaches
Ms. Akshada Gajbhiye, NCCS, India
11:45-12:45 pm
Session- VI: Panel Discussion: Status of Basic and Clinical
Cancer Research in India and around the Globe: Where do we
stand?
Moderators:
Dr. G. C. Kundu & Dr. S. A. Bapat
Panelists:
Dr. Shubhada Chiplunkar, Dr. Sudeep Gupta, Dr. Deirdre Coombe, Dr.
M. K. Bhat, Dr. A. Shiras, Dr. Diptendra Sarkar, Dr. Shona Nag, Dr.
Anupama Mane, Dr. C. B. Koppikar, Prof. Debabrata Chakravarti,
Prof. Tapas Kundu
12.45-1.45 pm
Lunch Break
Session-VII: Cancer Drug Development
Chairs: Dr. M. R. Wani & Dr. V. P. Kale
1.45-2.05 pm
I-17: The linkage between microtubule dynamics, apoptosis and drug
resistance
Prof. Dulal Panda, IITB, India
4
2.05-2.25 pm
I-18: Transcriptional deregulation and spatial organization of aneuploid
chromosomes in cancer cells
Dr. Kundan Sengupta, IISER, India
2.25-2.45 pm
I-19: Identification of altered cellular pathways associated with the
development of uterine cervical carcinoma in Indian patients
Dr. Chinmay Kumar Panda, CNCI, India
2.45-3.05 pm
3.05-3.20 pm
I-20: Targeting P21 activated kinase 1 (Pak1) to PAKup Pancreatic
Cancer
Dr. Suresh Rayala, IITM, India
S-8: Reassembling glioblastoma in a dish: From personalized therapy to
drug discovery
Mr. Aman Sharma, NCCS, India
3.20-4.50 pm Tea Break and Poster Presentation (Poster No. 31-60)
Session-VIII: Targeted Therapy in Cancer: Genetic,
Epigenetic & Chemical Biology Approach
Chairs: Prof. J. K. Pal & Dr. Manas Santra
4.50-5.10 pm
I-21: Melanoma Cell Adhesion Molecule (MCAM/CD146): Endocytosis,
cell migration and tumour formation
Prof. Deirdre Coombe, Curtin University, Australia
5.10-5.30 pm
I-22: Chromatin organizer SATB1 as molecular target for cancer
therapy: a novel mechanism for anti-cancer activity of Statins
Prof. Sanjeev Galande, IISER, India
5.30-5.50 pm
I-23: An update on PSP94: Structure, Function and application in
prostate cancer diagnosis
Dr. Smita Mahale, NIRRH, India
5.50-6.10 pm
I-24: Loss of 14-3-3
leads to the induction of an Epithelial
Mesenchymal Transition
Dr. Sorab Dalal, ACTREC, India
5
6.10-6.30 pm
I-25: Genome-wide analysis of squamous cell carcinoma of the oral
tongue reveals novel insights into wild type and mutant TP53
transcription program
Dr. Murali Bashyam, CDFD, India
6.30-6.50 pm
I-26: Integrated Genomics Approach to Identify Biologically Relevant
Alterations in Fewer Samples
Dr. Amit Dutt, ACTREC, India
7.00- 7.45 pm:
Transport to Le Royale Hotel
7.45-10.30 pm
Banquette Dinner at Le Royale Hotel
Day 3:
21st November, 2015
Session-IX: Tumor Suppressor, Regulation of Gene
Expression & Therapeutic Target in Cancer
Chairs: Dr. J. Joseph & Dr. Deepa Subramanyam
9.00-9.20 am
I-27: Regulation of tumor suppressor gene SMAR1 in cancers
Dr. Samit Chattopadhyay, IICB, India
9.20-9.40 am
I-28: Signaling Crosstalk and Gene Regulation in Cancer to Identify
Novel Target(s) for Therapeutics
Dr. Mrinal Ghosh, IICB, India
9.40-9.55am
S-9: Evaluation of agents of diverse origin for their anticancer activity
in vitro
Dr. Kalpana Pai, SPP University, India
9.55-10.10 am
S-10: Putting Cancer Cells to Sleep: A Novel Safer Approach for
Intervention
Dr. Gunjan Guha, SASTRA University, India
6
10.10-10.25 am
S-11: Evaluation of cinnamaldehyde functionalized magnetite
nanoparticles for hyperthermia and drug delivery applications in breast
cancer
Dr. Ruchika Kaul-Ghanekar, IRSHA, India
10.25-10.40 am
S-12: p53 causes histone deacetylation to downregulate Pro-Metastasis
Proteins Toca-1 and FBP17 in Breast Cancer
Dr. Harish Chander, Central University of Punjab, India
10.40-10.55 am
S-13: Dietary flavonoids for the reversal of P-glycoprotein mediated
Multi-drug resistance
Dr. Rajendra Prasad, Annamalai University, India
10.55-11.10 am
S-14:
iNOs+ macrophages represent Potential Alternate of
Radiotherapy for the Treatment of Pancreatic tumors
Dr. Hridayesh Prakash, University of Hyderabad, India
11.10-11.30 am
Tea Break
Session X: Nanomedicine in Cancer & Cancer
Metabolism
Chairs: Dr. D. K. Tewary & Prof. Ameeta Ravi Kumar
11.30-11.50 am
I-29: Protective metabolic cross-talk between tumour and stroma in
acute lymphoblastic leukaemia
Dr. Vaskar Saha, TMC, India
11.50-12.10 pm
I-30: Implantable nanomedicines: A short-cut to bypass systemic toxicity
and biological barriers
Dr. Manzoor K, Amrita University, India
12.10-12.30 pm
I-31: Chimeric Nanoparticle: A Platform for Simultaneous Targeting of
Phosphatidylinositol-3-Kinase Signaling and Damaging DNA in Cancer
Cells
Dr. Sudipta Basu, IISER, India
12.30-12.50 pm
I-32: Eco-fabrication of biomedically and technologically important
nanoparticles
Dr. Absar Ahmad, NCL, India
7
12.50-1.10 pm
I-33: Nanomedicines: Vehicle for Targeted Drug Delivery
Prof. Suresh Gosavi, SPP University, India
1.10-1.40 pm
Session XI: Valedictory, Poster Award & Concluding
remarks (Dr. S C Mande, Dr. Samit Chattopadhyay, Dr. G C Kundu
& Dr. S A Bapat)
Vote of thanks
Dr. Jyoti Rao
1.40-2.40 pm
Lunch
8