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Fitmaster
HEKA
FITMASTER features analysis and fitting routines for electrophysiological data.
Analysis can be performed on the levels of Sweeps/Traces and Series. Besides
standard fit functions such as Polynomials, Exponentials, Gaussians, and
Boltzmanns, tailored functions to fit e.g. whole-cell current traces according to
Hodgkin&Huxley gating formalism, current-voltage relationships and dose-response
curves allow publication-proof analysis of your data.
The experienced patch clamp investigator will be fascinated by the versatility of the
program and logical structure of the functions. All of the features of
PATCHMASTER's Online Analysis are also present in FITMASTER. In principle,
FITMASTER extends these capabilities by adding more specific analysis features
and the generation of an analysis tree. The way FITMASTER works is tightly linked to
the tree structure of data generated by PATCHMASTER up to the level of a Series.
Hence, FITMASTER has equivalent hierarchical levels of analysis corresponding to
the tree levels featured in the Replay data tree. The analysis is organized in a
structured way, relating to Sweeps and Series. The lowest level is the analysis of a
raw data trace, a Trace. The TraceFit dialog provides tools for selecting a section of
the trace for analysis and specifications of the type of analysis to be performed. The
values determined by this sweep analysis can be further processed in SeriesFit. But
in contrast to PULSEFIT, FITMASTER allows pooling of data on the level of the
Series by introducing the new waves buffer concept. Several results of the TraceFit
can be compiled in the waves buffer and then displayed in the SeriesFit graph.
Several fit functions can be used to describe this ensemble of data points.
Features:
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Analysis is organized in a structured way
Merging results form different experiments
Analysis of train-type data
Clipboard support
Fit to raw data traces
Current/voltage relationship
BioMedical Instruments
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