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University of Virginia Department of Student Health Gynecology Clinic If you are taking Yasmin or Yaz… Your oral contraceptive pill is different from other brands. Like most combined oral contraceptives, Yasmin and Yaz contain ethinyl estradiol (a synthetic estrogen). But instead of a progestin (synthetic progesterone) like all other hormonal contraceptives, Yasmin and Yaz contain drospirenone, which is closely related to spironolactone, a medication that can be used in higher doses to treat high blood pressure. Drospirenone interferes with the normal functioning of your kidneys in such a way as to prevent the excretion of potassium. When potassium is not excreted by the kidneys, it can build up in the bloodstream. If the levels become too high, you are at risk for an irregular heart rhythm. Although rarely fatal in young people, an irregular heart beat can be dangerous by causing lightheadedness or fainting. To reduce your chance of this potentially serious complication, you should avoid taking other medications that can also raise your potassium levels. If you are taking Yasmim or Yaz, do not take any of the following without checking with your health care provider first: • More than 200 mg per day of pain or arthritis medicine such as aspirin, ibuprofen, or naproxen sodium (also known as NSAIDs), whether generic or brand names such as Advil®, Motrin®, Naprosyn® ,Nuprin®, Aleve®, Bextra®, Celebrex®, Ecotrin®. • A potassium supplement, or a diuretic ("water pill") such as spironolactone, triamterene, or Aldactone®. • A salt substitute such as Nu-Salt®, AlsoSalt®, LoSalt® or others. • An ACE inhibitor such as captopril, enalapril, lisinopril, Accupril®, Capoten®, Lotrel®, Mavik®, Monopril®, Prinivil®, Vasotec®, Zestoretic®, or Zestril®. • Angiotensin II receptor inhibitors such as Cozaar®, Diovan®, Avapro®, and others • Heparin. • Sports drinks with electrolytes. You should also avoid eating large amounts (more than three servings per day) of high-potassium foods. See the reverse of this page for a list of common foods that are high in potassium (from: http://www.kidney.org/ATOZ/atozItem.cfm?id=103). C.M. Peterson, M.D. July 2008 What foods are high in potassium (greater than 200 milligrams per portion)? The following table lists foods that are high in potassium. The portion size is ½ cup unless otherwise stated. Please be sure to check portion sizes. While all the foods on this list are high in potassium, some are higher than others. High-Potassium Foods Fruits Vegetables Other Foods Apricot , raw (2 medium) dried (5 halves) Acorn Squash Artichoke Bran/Bran products Avocado (¼ whole) Bamboo Shoots Chocolate (1.5-2 ounces) Banana (½ whole) Baked Beans Granola Cantaloupe Butternut Squash Milk, all types (1 cup) Dates (5 whole) Refried Beans Molasses (1 Tablespoon) Dried fruits Beets, fresh then boiled Figs, dried Black Beans Grapefruit Juice Broccoli, cooked Nutritional Supplements: Use only under the direction of your doctor or dietitian. Nuts/seeds Honeydew Brussels Sprouts Nuts and Seeds (1 ounce) Kiwi (1 medium) Chinese Cabbage Peanut Butter (2 tbs.) Mango(1 medium) Carrots, raw Salt Substitutes/Lite Salt Nectarine(1 medium) Dried Beans and Peas Salt Free Broth Orange(1 medium) Greens, except Kale Snuff/Chewing Tobacco Orange Juice Hubbard Squash Yogurt Papaya (½ whole) Kohlrabi Pomegranate (1 whole) Lentils Pomegranate Juice Legumes Prunes Mushrooms, canned Prune Juice Parsnips Raisins Potatoes, white and sweet Pumpkin Rutabagas Spinach, cooked Tomatoes/Tomato products Vegetable Juices C.M. Peterson, M.D. July 2008