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Transseptal Puncture Technique Saibal Kar, MD, FACC, FAHA, FSCAI Heart Institute, Cedars-Sinai Medical Center, Los Angeles, CA Disclosure Statement of Financial Interest Saibal Kar, MD, FACC Within the past 12 months, I or my spouse/partner have had a financial interest/arrangement or affiliation with the organization(s) listed below. Affiliation/Financial Relationship Company • Grant/Research Support • Abbott Vascular,Boston Scientific, St Jude Medical, Circulite, Coherex, Gore, Biotronics • Consulting Fees/Honoraria • Abbott Vascular, Boston Scientific, St Jude Medical, Gore • Other Financial Benefit • Coherex, Biosensors International Introduction • Transseptal access of the left atrium, was initially developed to directly measure pressures of the left atrium and ventricle • In the present era, transseptal access of the left atrium is critical step for a wide variety of electrophysiological and interventional procedures • Accurate and safe transseptal puncture is therefore important for the success of these procedures Transseptal interventions • Electrophysiological procedures – Pulmonary vein isolation • Mitral valve interventions – Valvuloplasty, Repair, replacement, paravalvular leak closure • Left atrial appendage closure • Left sided support systems: – Tandom Heart Equipment for Transseptal Puncture 71cm BRK/BRK1 & 67cm SL1 Equipment for Transseptal Puncture Dilator Ross needle Sheath Sheath NRG® Radiofrequency Needle( Baylis Medical) Image guidance for successful transseptal puncture • Fluoro : – Two views : AP and lateral or RAO and LAO • Echo guidance – Transesophageal echo or intracardiac echo • Combined fluoro and echo – Accurate location of TS puncture based on pathology and procedure – Can be used to guide the rest of procedure – Early detection of complications Fluoroscopy: Two orthogonal views should be used Antero posterior View G. Joseph CCVD 42:138,1997 Fluoroscopy: Two orthogonal views should be used Lateral View 90 degree lateral Basic TEE views for optimal Transseptal puncture Bicaval view: LA RA Short axis view SVC 4 chamber view LA LA AO RA LV SVC RV Technique in different procedures • Mitral valve interventions • Left atrial appendage closure • Closure of paravalvular leak Mitral Valvuloplasty Posterior and superior Anterior puncture : Difficulty to advancing Stiff balloon catheter in LV MitraClip System Steerable Guide Catheter Clip Delivery System Stabilizer MitraClip Transseptal puncture during MitraClip Procedure Too close to MV Too posterior from MV Correct TS for MitraClip; 4.0 - 4.5 cm away from MV Transseptal puncture during MitraClip Procedure Appropriate location determines the success of the procedure Short axis: Posterior Bicaval view: Superior 4 chamber view: Distance From Puncture to point of coaptation 4 to 4.5 cm Special situation MitraClip for Flail leaflet 4 chamber view: Distance From Puncture to point of coaptation 4 to 4.5 cm Bicaval view: Superior Short axis: Posterior Special situation Functional MR with very large left atrium 4 chamber view: Distance From Puncture to point of coaptation 4 to 4.5 cm Bicaval view: Low Short axis: Mid or anterior TS puncture location : determining factors • Left atrial size • Type of pathology – Functional – Flail/Prolapse • Region of MV involvement – Medial aspect ( A3P3) – Lateral aspect (A1P1) Optimal location for TS puncture for left atrial appendage occlusion Low Posterior • Posterior Puncture LAA Use of Fluoro and TEE for Transseptal puncture Appropriate location and prevention of tamponade Bicaval view (90 to 100º) Short axis view ( 35 to 50º) LA LA RA RA Mid Fossa AO SVC Mid Fossa / Posterior Advantages of TEE guided Transseptal puncture • Accurate localisation • Avoid Puncture of the posterior wall or roof of LA • Early detection of pericardial effusion Posterior Puncture Anterior puncture LAA Other Important Tips during Transseptal Puncture • Avoid excessive tenting of septum • Protect Needle tip with wire • Use of stylet through needle to puncture septum • Use of radiofrequency needle, Optimal TS: Avoid/treat complications • Cardiac perforation/cardiac tamponade – Prevent it – Early recognition – Treatment • Thrombus formation – Prevention – Treatment Conclusion • Trans-septal access is a critical step to several structural procedures • Echo and Fluoro guidance is essential • Puncture is dependent on – Procedure – Location of the pathology – Size of the Left atrium • Be vigilent about potential complications