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MUSCLE ANATOMY Copy only the red text! LEARNING GOALS • I will understand the anatomy of the muscle. • I will understand the simple neurology of the muscle. BASIC UNIT • Skeletal muscles are made up of cylinder shaped cells called fibres. • Each fibre is made up of long slender cells (myofibrils) ranging from 1mm to 50 mm in length • In each muscle, fibres are grouped together in bundles. • Bundles of muscle fibre are called fasciculi • The arrangement of the bundle determines the shape and size of each muscle. EPIMYSIUM • Skeletal muscles are sheathed by a tough layer of connective tissue called the epimysium. • Envelopes the entire muscle • Extends beyond muscle to become tendon • Tendon becomes bone’s periosteum • This is the attachment site of muscles: origin and insertion PERIMYSIUM • Sheath of connective tissue binding groups of muscle fibres together ENDOMYSIUM • Connective tissue surrounding a muscle fibre • In between fibres SARCOLEMMA • Plasma membrane that lies beneath the endomysium • Contains the muscle cell’s cytoplasm SARCOPLASM • Muscle cell’s cytoplasm • Large amounts of stored glycogen • Protein myoglobin • High concentration of Ca2+ and mitochondria SARCOMERES • Repeating structural units or compartments containing proteins ‘actin’ and ‘myosin’ • Myosin (thick filament) and Actin (thin filament) • Myosin (looks like golf club) head has an attachment site for Actin • Actin has a binding site for Myosin • Actin has two other proteins: troponin (Ca) and tropomyosin (covers binding site on actin) SARCOPLASMIC RETICULUM • Network of web like channels involved in muscle activation • Release Ca • Actin and myosin slide across one another during muscle contraction NEUROMUSCULAR FUNCTION NERVOUS ARE YOU? • Skeletal muscle is activated by the nervous system. • The nervous system can be divided into • central (spinal cord) • peripheral (away from spinal cord) • The nervous system can also be divided into • sensory (collects information from sensors and sends information to brain) • motor (sends signals to activate muscle contraction) • Motor nerves extend from spinal cord to muscle fibers MOTOR UNIT • A single nerve that activates a group of fibers is called a motor unit. • Large muscles may have hundreds of fibers in each unit (quads) • Small muscles may have as little as 10 fibers in each unit (muscles of the eye) • The smaller the motor unit the more precise the movement. • Nerves transmit impulses in “waves” that ensure smooth movements. • A single nervous impulse and the resulting contraction is called a muscle twitch. • One neuron or nerve (called the “motor neuron”) may be responsible for stimulating a number of muscle fibres. ALL OR NONE PRINCIPLE • An impulse from the CNS needs to be of a certain magnitude to cause fibers to contract. • A smaller impulse does not result in a smaller contraction. • Once the needed magnitude is reached, the muscle contracts. • This is called the all-or-none principle. When a motor unit contracts it will contract completely or not at all. • In other words, if a motor unit consists of 10 muscle fibres (or 800 muscle fibres) and they are “turned on,” either all fibres will contract or none will contract. INTRAMUSCULAR COORDINATION • Increased strength requires more motor units being activated. • This is called intramuscular coordination. • Trained athletes are able to recruit more motor units than untrained individuals (Olympic weight-lifters – 85%, untrained individuals – 60%). • Trained athletes can further increase strength only by increasing muscle diameter. INTERMUSCULAR COORDINATION • Recruiting motor units from different muscles allows for improved performance. • This is called intermuscular coordination. • A high performance athlete has trained all agonists and antagonists to work together for a fluid skill movement. RECIPROCAL INNERVATION • Muscles seldom work alone. • In almost all cases muscles work in pairs or groups to produce movement. • When you move your body, a coordinated action of several muscles must occur. • Different muscles attached around the joint cooperate to produce a smooth efficient movement. • Reciprocal innervation is a process which produces the exact amount of relaxation in the antagonist to balance the amount of contraction generated in the agonist. • For example, in the human arm, the triceps acts to extend the lower arm outward while the biceps acts to flex the lower arm inward. • In order to reach optimum efficiency, contraction of opposing muscles must be inhibited while muscles with the desired action are excited. • This reciprocal innervation occurs so that the contraction of a muscle results in the simultaneous relaxation of its corresponding antagonist. LEARNING GOALS • I will understand the anatomy of the muscle. • I will understand the simple neurology of the muscle.