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TREATMENT Lung cancer treatment depends on what kind of lung cancer you have, its stage, and which biomarkers, if any, are present in your cancer. Your health care team will also consider your overall health and wishes when planning your treatment. Some of the most common treatments for lung cancer include: Surgery. Each lung is divided into sections, or lobes. The right lung has three lobes: the upper, middle, and lower lobes. The left lung has just two lobes, the upper and lower. If the cancer is in only one lobe of one lung, surgery can remove the cancer and offers the highest rate of cure. Depending on the location and size of the lung cancer, surgeons may remove just part of a lobe (this kind of surgery is called a segmentectomy, or “wedge” resection), an entire lobe (lobectomy), or an entire lung (pneumonectomy). A person can survive with just one lung. Sometimes surgical removal of a cancer can be done with thoracoscopy, where instruments are inserted into the chest and guided by a small camera. When the size and location of the tumor make this possible, thoracoscopy has the advantages of smaller incisions than with standard surgery, and shorter recovery times. Ask your medical team if you are eligible for thoracoscopy. Surgery may also be used to treat advanced lung cancer, either as part of a combined approach with other forms of therapy, or to relieve symptoms like shortness of breath from fluid accumulation around the lung. Chemotherapy. Chemotherapy uses medication to kill cancer cells. Most chemotherapy drugs are given directly into the veins through an IV line, although some come in pill form. If chemotherapy is going to be delivered through the veins, clinicians will often surgically implant a special “port” into the upper part of a patient’s chest before chemotherapy treatment begins. The port leads into a major vein; health care providers can easily and reliably access the port to deliver IV chemotherapy. Ports and other types of long-term IV access are commonly used for chemotherapy because treatment often extends over many weeks. A port or long-term IV access allows patients to avoid an IV “stick” every time they go for chemotherapy. Chemotherapy is the treatment of choice for small cell lung cancer, but is also used commonly to treat non-small cell lung cancers in Stages 2, 3 and 4. Chemotherapy can be used alone or in conjunction with other cancer treatments. Sometimes, chemotherapy is used before surgery to shrink tumors and make them easier to remove surgically. Sometimes, chemotherapy is used after surgery to treat any remaining cancer. Targeted therapy is a relatively new form of chemotherapy for patients with cancers that have specific features that make them vulnerable to specific drugs. Biomarker testing is very helpful to see whether these drugs will be effective. Radiation Therapy. Radiation therapy uses high-energy x-rays or other forms of radiation to kill cancer cells. Radiation can be administered in several different ways, but most involve a source outside of the patient. During treatment, the patient is positioned on a special treatment table while a machine delivers invisible radioactive beams through the skin to the cancer. Because radiation can harm healthy tissue, the radiation oncology team will carefully measure and mark the spot that should receive radiation. Each time you have treatment, the beams will be aimed at this precise spot. Each treatment only takes a few minutes. Radiation therapy for lung cancer is usually given several days each week for several weeks. The schedule is always customized to the patient and the type, size, and location of the cancer. Your health care team will customize the plan for radiation depending on the type, size, and location of the cancer with the goal of eliminating as much cancer as possible with minimal side effects. Precise planning is important because radiation can damage normal tissue along with killing cancer cells. Other Treatments Other treatment options may be used in certain situations. Radiofrequency ablation uses heat to kill cancer cells, delivering heat through a thin, needle-like probe through the skin near the cancer. Photodynamic therapy (PDT) uses a special light delivered through a bronchoscope to cancer cells inside the breathing tubes; laser beams may be delivered through a bronchoscopy to kill cancer cells to open blocked airways, and cryosurgery uses extreme cold to kill cancer cells. Your health care team will be able to discuss these options and whether they would be right to treat your type of cancer. Lung cancer treatments have side effects. Cancer treatment may include fatigue, nausea and vomiting, loss of appetite, weakness, hair loss, sores in the mouth and/or at the site of radiation treatment, decreased immunity, memory problems, pain and discomfort, diarrhea or constipation, and skin rashes. The side effects you experience will depend on what treatments you receive and how your body responds to the treatments. Also, remember that side effects may be eased using medication before you even begin treatment. (It’s common, for instance, to give anti-nausea medication before chemotherapy.) Ask your health care providers about the possible side effects of your lung cancer treatment, and ask what you can do to help manage any side effects. Be sure to report any side effects to your health care provider. Your health care provider can’t help you feel better if he or she doesn’t know what’s going on with you.