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BMI 205: PRECISION PRACTICE WITH BIG DATA Daniel L. Rubin, MD, MS Associate Professor of Radiology, of Medicine (Biomedical Informatics), and of Biomedical Data Science Department of Radiology Stanford University Outline • Course information • Introduction: Big Data and precision practice • Big Data challenge: Decision making in cancer treatment • Big Data solution: “Learning Healthcare Systems” in cancer • Conclusion Course goals (1) • Show how medical practice and research are being transformed by large amounts of data (clinical, molecular, imaging) • Show how computer methods can enable precision care – Help physicians recognize the best therapy – Get the knowledge they need when they need it – Discover new knowledge and challenge established dogma – Broaden clinical decision making beyond just published knowledge and physician experience Course goals (2) • Some major topics illustrated – Disease sub-typing/patient profiling – Data mining – Predicting treatment response – Personalized treatment – Getting computers to work with unstructured data (text and images) – The “Learning Healthcare System” Course administration • Location: LKSC, Room 120 – * Please note October 19th class will be in LKSC 130 * • Time: Wednesdays 12:30-1:20pm, lunch will be provided and served at 12:00pm. • Videos: Recordings will be posted after each lecture Course administration • Units: 1 unit • TA: Alice Yu ([email protected]) • Requirements: Weekly attendance – If you miss a session, view recorded seminar and complete a short written assignment. – The assignment will be posted shortly after lecture and due prior to the next scheduled talk. – Submit to [email protected] with BMI205 at the beginning of the subject line. Course website http://bmi205.stanford.edu/