Download Mapping of Research Collaborative Networks Web Tool Box

Mapping Science and Technology
with Heterogeneous Data Analysis
Tools for strategic management of innovation –
Biotech.Obs
Andrei Mogoutov | AGUIDEL
Paris - Montreal
www.aguidel.com
Tools for strategic management of innovation
•
Data collection and management « Biotech » actors using online
questionnaires, publications, patents, existing databases, institutional
contacts, company websites, news and press releases
•
Services/applications
–
–
–
–
–
–
–
–
–
–
–
–
Positioning of companies, projects, products, patents, publications, research fields
Startup support
Early warning
Partnership network building
Advice on local promotion
Advice on foundation and management of « clusters »
Evaluation of projects
Market and technological studies
Benchmarking, competitiveness
Consultancy for valorization actors
Communication strategy development
Academic research
•
Software solutions: On-line applications, off-line applications, customized
solutions, integration of customers data, analytical tools
•
Data analysis: Custom methods for the analysis of complex & heterogeneous
datasets, text and data mining, relational analysis, GIS, scientometrics
Projects & partners
• CEA (French Nuclear Energy Commission): Nano/Bio - clusters Dynamics of Nano-bio-technology field.
• Biotech Clusters - Genopole Evry – research labs, startups & big
pharma
• Public Health Canada: Clusters of Nanotechnologies in Canada,
Obesity issues and research,
• Regional innovation agencies – “Technopole” Angers
• INSERM: Evaluation of research laboratories, strategic analysis of
neurosciences research,
• INRA/CNRS: Mapping of controversies and research fields in
genetically modified food safety
• McGill University: Anticancer drugs clinical trials, Microarray R&D,
Cancer research worldwide, Cancer and genetics, Standardisation
and Migraine research,
• University of Vienna: Scientometrics of Social Studies of Science
Field
• Big International Foundations: Open Society Institute, WWF Ford
foundation, McArthur's foundation, Govcom.org foundation various
political, ecological and technological issues
• Private companies: industry, big pharma, telecoms, medical imaging
• Investors, business angels
../ANALYTICAL DIMENSIONS
SPACE
TIME
Client side Apps
News RSS Feeds
Client side Apps
News
Client/Server
Apps
RSS Feeds
archives
Client/Server Apps
News RSS Feeds
archives
Client/Server
Client/Server side
CONTENT
Client side Apps
News, Web search,
Blogs
Client/Server
Apps
Client side Apps
News archives,
Web search, Blogs
Client/Server
ACTORS & NETWORKS
Client/Server
side Apps
RSS Feeds
archives +
Scientometrix
Client/Server
Apps +
ANALYTICAL
DIMENSIONS/DATA/METHODS/TOOLS
side Apps +
Apps + offline apps side Apps +
side
Information « Spaces »
•
•
•
•
•
•
•
•
•
•
•
News Streams
Blog Sphere
Web Sites
E-Communication (Mailing Lists, Forums)
Scientific Information Data Bases (Publications, Patents)
Offline “Literature”
Press archives
Surveys/ Interviews
Traditional Media (TV, Radio) archives
Specific Data Bases
Etc ?
Traditions/Methods/Solutions
•
•
•
•
•
•
•
•
Statistics / Data Mining
Textual Analysis Tools / Text Mining
Web Cartography
Scientometrics
Tools for Qualitative Data Analysis
Social / Socio-Technical Networks
GIS
Etc.
Heterogeneous Data Sets: Back Office
Press archives
Online Data
Collection
Tools
Parsing & Matching
System
“Offline”
Questionnaires
Actor
Location
Existing
Databases
Contents
Classification
Schema
Actor
Identity
Sci publications
Patents
Web Crawler
NETWORK ORIENTED DATABASE
Design of Analytical Solution
OFF-LINE
DATA UPDATE
ON-LINE
Front Office
- graphical/analytical interfaces
(GIS, Relational Mappings,
Statistical Charts)
- statistical tables, indicators and
textual synthesis
- integrated querying tools
Middle Office
- a layer of analytical queries
- pre-defined queries for multilevel data aggregation
and synthetic analysis and
indicators
FEED-BACK
Back Office
- data tables
- web crawler
- matching tools
- tools for textual analysis
- tools for data update and control
“Online” Data Collection Tool
Front Office “Desktop”
350
300
250
200
150
100
50
0
cancer family
history
risk factors
hormonalcontraception
personal
medical
history
family relatives environment- cancer genes
tobacco
Scientometrix – Publications and Patents
PubMed (Medline)
ISI
Derwent
/Scientometrics/results (ReseauLu Sci_Metrix)
10
00
sugar crops
public opinion
phosphinothricin
acetyltransferase
1
Weed management -0
0
oilseed plants
geneflow
rape
release
GM Food
safety
glyphosate
sugarbeet
risk
regulations
biosafety
maize
DNA
cereals
cultivars
Detection
contamination
backcrossing
seed production
intergeneric hybridization
volunteer dispersal
interspecific hybridization plant genetic resources
pollen
plants
population dynamics
safety
gene flow
hybridization
Herbicide resistant weeds
population genetics
crop plants as weeds
1
ecology
Biology
evolution
tomatoes
Oil plants
models
reviews
food legislation
transgenics
methodology
foods
proteins selectable markers
analytical methods
labelling
detection
food products
fruits
polymerase chain reaction
vegetables
soyabeans
1
0
pollination
2
2
0
2
0
2
0
3
1
0
2
1
9
0
1
1
9
0
1
9
9
1
9
8
1
9
7
1
9
6
1
9
5
1
9
4
1
9
3
1
9
2
1
9
1
1
9
8
0
1
9
8
9
1
9
8
1
9
8
7
9
8
6
8
5
4
European Union
allergens
legislation
food allergies
consumer attitudes
food safety
glufosinate swede
herbicides
rape
weed control
genetic
chemical
markers
herbicide resistance
control
weeds
flowering
invasion
wild relatives
introgression
tolerance
plant breeding
environmental impact
risk
assessment
nontarget organisms
potatoes
lectins
pesticides
insecticides entomopathogenic bacteria
entomopathogens
Pathogens
biological
agricultural entomology
beta-glucuronidase nontarget effects
control
toxins
nucleotide sequences
control
bacterial insecticides
agglutinins
marker genes
effects natural enemies
gene transfer
root
Pest control
gene expression
crops
microbial pesticides
pest resistance
promoters
parasitoids
genes leaves
trypsin
inhibitors
Insect
pests
genetics
reporter genes
insect control
genomes tobacco
rice enzymes
biological control agents
lines
proteinase
inhibitors
plant pests
molecular genetics
growth
larvae
resistance
Potyvirus
plant parasitic nematodes
survival
plant diseases
Mol. Biol.
and Virol.
stimulant plants plant pathogens
plant pathology
coat proteinsdisease resistance
plant pathogenic bacteria
plant pathogenic fungi
toxicity
Agr. entomology
Top Journals
N. Art.
Journal of Economic Entomology
98
Theoretical and Applied Genetics
41
Biotechnology and Development Monitor
37
Nature
33
Molecular Ecology
33
Transgenic Research
32
Nature Biotechnology
32
OCL - Oleagineux, Corps Gras, Lipides
30
Molecular Breeding
28
Science
27
Euphytica
26
Current Science
23
Biofutur
23
Environmental Entomology
22
Proceedings of the National Academy of
Sciences of the United States of America
20
/tools (ReseauLu X2 SciMetrix)
/tools (ReseauLu X2 SciMetrix)
../Stem Cells - Counts
6000
5000
4000
3000
2000
1000
0
1960
1965
1970
1975
1980
1985
1990
1995
2000
2005
2010
STEM CELLS - AUTHORS
Name
Nb Pub
WEISSMAN, IL
45
ZSEBO, KM
26
ORKIN, SH
26
OGAWA, M
25
GAGE, FH
24
JAENISCH, R
22
BRADLEY, A
22
ROSSANT, J
22
MOORE, MAS
21
EAVES, CJ
21
WILLIAMS, DA
19
LANSDORP, PM
19
NISHIKAWA, S
18
MULLIGAN, RC
18
SMITHIES, O
18
HUMPHRIES, RK
16
ALT, FW
16
DICK, JE
16
MAK, TW
15
DEXTER, TM
15
ARMITAGE, JO
15
RAJEWSKY, K
14
MORRISON, SJ
14
MoyenneDePosition
Name
0,87 WEISSMAN, IL
0,83 BRADLEY, A
0,76 ROSSANT, J
0,86 MULLIGAN, RC
0,62 ZSEBO, KM
0,82 MAK, TW
0,95 JAENISCH, R
0,71 RAJEWSKY, K
0,84 ORKIN, SH
0,83 OGAWA, M
0,94 GAGE, FH
0,54 LANSDORP, PM
0,27 WAKEHAM, A
0,86 SMITHIES, O
0,38 GERTSENSTEIN, M
1 CAPECCHI, MR
0,65 REYNOLDS, BA
0,84 WILLIAMS, DA
0,7 MOORE, MAS
0,88 DEXTER, TM
0,91 WEISS, S
0,81 LI, E
0,47 LANGLEY, KE
0,3 BRONSON, RT
0,44 NISHIKAWA, S
0,78 SORIANO, P
NbCit
10455
8217
7859
7029
7016
6275
5798
5729
5471
5368
5244
5197
4889
4850
4611
4519
4487
4429
4301
4025
3985
3957
3893
3850
3831
3766
NbCitPos
8971
7435
5398
6451
5119,75
5666
5588,5
3963,5
4472
4483,75
4905,5
2774,25
1277,5
4074
1503,75
4519
3149
3444,5
2947,75
3806
3598,5
3335,5
1782,25
1298,5
1669
3296,5
Stem Cells Co-Citation
STEM CELLS – Collaboration networks
STEM CELLS – International Collaboration
STEM CELLS – Emerging themes
Scientometrix: Early Warning: Strategic Diagrams of Research
Community Evolution: biosafety research
0,1
0,001
0,01
0,1
2000-2003
0,0001
TABASHNIK BE - 250
GOULD F - 258
HILBECK A - 92
ELLSTRAND NC - 114
DANIELL H - 89
SCHULER TH - 64
LOSEY JE - 59
SAXENA D - 47
SCHUBBERT R - 41
MALONE LA - 35
GATEHOUSE AMR - 71
ROUSH RT - 96
PILCHER CD - 49
SIMS SR - 59
PERLAK FJ - 98
NIELSEN KM - 50
MCGAUGHEY WH - 98
CHEVRE AM - 48
CRAWLEY MJ - 76
ANDOW DA - 44
SHELTON AM - 43 LIU YB - 49
KOZIEL MG - 72
TANG JD - 47SCHEFFLER JA - 50
PADGETTE SR - 43
DALE PJ - 85
TAYLOR SL - 45 ALSTAD DN - 44
STEWART CN - 49
SNOW AA - 41
JORGENSEN RB - 49
ONSTAD DW - 41
JOHNSON MT - 45
RAYBOULD AF - 57
CAPRIO MA - 37
LEFOL E - 35
KLINGER T - 54
MACINTOSH SC - 37
MIKKELSEN TR - 54
JEFFERSON RA - 36
LINDER CR - 40
HILDER VA - 37
DEBLOCK M - 43
RIESEBERG LH - 37
MEYER R - 42
BARTSCH D - 45
0,01
WILLIAMSON M - 37
MICHAUD D - 36
1984-1999
0,001
Scientometrix/ Adds Heterogeneous Networks
Companies & Technologies
Scientometrix / Adds: Actor/Networks
R&D Collaboration Strategic Diagram
8%
Centrality
Glaxo SmithKline plc
Pharma Group I
Central, Star-like hierarchical networks
Aventis
7%
Johnson & Johnson
Pfizer
6%
Roche
Bristol-Myers Squibb Co.
Novartis
Wyeth
Pharma Group II
Less central, Less hierarchical
5%
Pharmacia
Eli Lilly and Co.
Applera Corporation
Abbott
Valentis Inc.
National Institutes of Health
Genzyme Corp.
4%
AstraZeneca
Amersham Pharmacia Biotech
Merck & Co. Inc.
Elan Corporation plc.
Chiron Corp.
Platform Tech. Companies
Clique-like, complex networks
Bayer AG
3%
Incyte Genomics
Schering AG
Genentech Inc. Schering-Plough Corp.
Millennium Pharmaceuticals Inc.
Monsanto
University of California
Boehringer Ingelheim
EI DuPont de Nemours & Co. Inc.
2%
Amgen
Celltech Group plc
Medarex Inc.
Pharmacopeia Inc.
Novo Nordisk
Perkin
Affymetrix Inc.
Baxter International
inc.Elmer
Shire Pharmaceuticals Group plc
Vertex Pharmaceuticals Incorporated
Corixa Corp.
Merck KGaA
Mitsubishi Group Harvard University
ISIS
Pharmaceuticals
Inc.
Johns Hopkins University
Harvard Medical School
Abgenix
Inc.
Akzo Nobel NV
Lion Bioscience AG
University of Texas
Interneuron
MedImmune Inc.
ArQule Inc.
Biogen Inc.
Procter & Gamble Co.
Acambis plc
Lexicon Genetics Incorporated
Sequenom Inc. Becton Dickinson
BASF
and Co.
Yamanouchi Pharmaceutical Co. Ltd.
Massachusetts Institute of Technology
SkyePharma
Xenova Group plc
Mds Inc.
Sanofi-Synthelabo
Duke University Health System
Cephalon
Inc.
Sankyo
Fujisaw a Healthcare INC
OSI Pharmaceuticals Inc.
Allergan INC.
Genome Therapeutics Corp.
Takeda Chemical Industries Ltd
Dyax Corporation
Cell Pathw ays Inc.
Applied Biosystems Group
Ligand Pharmaceuticals
Medtronic Inc.
Chugai Biopharmaceuticals Inc.
Cytogen Corp. Stanford University School of Medicine
Bio-Technology General Corp.
Xoma ltd.
Biovail Corporation
Aurora Biosciences Corp.
Solvay Pharmaceuticals inc
Schw arz Pharma AG
Corning Inc Tyco International Ltd.
Watson Pharmaceuticals Inc
Nycomed Amersham plc.
QUIDEL Corp.
Teva Pharmaceutical Industries Ltd
Degussa AG
King Pharmaceuticals Inc
IVAX Corporation
Cardinal Health Inc.
1%
ICN Pharmaceuticals Inc.
0%
0%
2%
4%
6%
8%
10%
Density
Scientometrix /GIS Spatial Network - Collaboration between NanoBiotech Clusters

01803
01730
01801
Scientometrix /GIS
Space
Biotech Clusters

02451
02139
02118
02210
Boston

02481
Boston Region
02132

01801



Scientometrix /GIS
Space
Nano-Biotech Clusters
Scientometrix /GIS – Zooming In
Canadian Nano-Bio publications by province and by discipline
Scientometrix /GIS – Zooming In
Number of publications by type, Montreal region
Scientometrix /GIS – Zooming In
Sub-clusters of the Montreal region, Note the Bio/medicine sub cluster in Laval.
Web Cartography III
IssueCrawler Project – GovCom.Org, Amsterdam (R Rogers et al)
Technology transfer: Industrial Partners of
INSERM
450
400
600
GROUPE
PME
350
500
START-UP
Total
300
400
250
300
200
150
200
100
100
50
0
0
1980 1982 1983 1984 1985 1986 1987 1988 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003
Industrial partners of INSERM: Emerging domains
INSERM: international Collaboration
Technologies & Companies
Network in Time
News
The North Korean English News
Space, Sept. 15 – Nov. 15, 2003.
Findings:
Whitehouse.gov (press release) couches
North Korea in terms of regime
change and human rights. The
only other outlet that does so is
Frontpagemag.org, a site which at
the time of this map, extolled
surfers to sign and e-petition and
help “Stop the Left’s Anti-American
Agenda… Help expose terrorists
in our midst>”
Connecting regime change to war is
done by Fox News, Newsweek,
and Asia Times online. Thus it is
clear that these media outlets are
framing regime change in terms of
military conflict.
Regime Change and Reunification are,
basically, disconnected. Thus
there is little talk of a German
model achievement of Regime
Change.
The Financial Times subscription
service, a strong example of the
corporate angle on the issue,
presented North Korea only in
terms of regime change, notably
isolating the issue from conflict,
reunification, famine and other
issues.
Only CNN is able to connect famine and
reunification, one of the more
practical and meaningful
associations between the issues of