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BY:asst.prof.Dr.firas AL-bawi Infectious Coryza (IC) INTRODUCTION Infectious coryza (IC) is an acute respiratory disease of chickens caused by the bacterium known as Avibacterium paragallinarum, once known as Haemophilus paragallinarum and Haemophilus gallinarum. Av. paragallinarum and Av. gallinarum are both Gram-negative nonmotile bacteria. In 24-hour cultures, both appear as short rods or coccobacilli 1–3 mm in length and 0.4–0.8 mm in width, with a tendency for filament formation. ETIOLOGY Hemophilus gallinarum X-(hemin) and V-(nicotinamide adenine dinucleotide—NAD) factors Hemophilus paragallinarum V-factor H. gallinarum and H. paragallinarum are identical in all other growth characteristics and disease producing potential. Incidence and Distribution Infectious coryza occurs wherever chickens are raised. Natural and Experimental Hosts The chicken is the natural host for H. paragallinarum The following species are refractory to experimental infection: Turkey, pigeon, sparrow, duck, crow, rabbit, guinea pig, and mouse. Age of Host Most Commonly Affected All ages are susceptible. Less severe in juvenile birds. The incubation period is shortened, and the course of the disease tends to be longer in mature birds, especially hens with active egg production. Transmission, Carriers, and Vectors Chronic or healthy carrier birds have long been recognized as the main reservoir of infection. 1 BY:asst.prof.Dr.firas AL-bawi On farms where multiple-age groups are brooded and raised, spread of the disease to successive age groups usually occurs within 1—6 weeks after such birds are moved from the brooder house to growing cages near older groups of infected birds. Infectious coryza is not an egg-transmitted disease. Incubation Period The characteristic feature is a coryza of short incubation that develops within 24—48 hours after inoculation of chickens with either culture or exudate. Susceptible birds exposed by contact to infected cases may show signs of the disease within 24—72 hours. In the absence of a concurrent infection, IC usually runs its course within 2—3 weeks. Clinical Signs The most prominent features are an acute inflammation of the upper respiratory tract including involvement of nasal passage and sinuses with a serous to mucoid nasal discharge, facial edema, and conjunctivitis. Swollen wattles may be evident, particularly in males. Rales may be heard in birds with infection of the lower respiratory tract. Birds may have diarrhea, and feed and water consumption Usually is decreased; in growing birds, this means an increased number of culls; and in laying flocks, this means a reduction in egg production (10—40%). A foul odor may be detected in flocks in which the disease has Become chronic and complicated with other bacteria. Gross lesion H. paragallinarum produces an acute catarrhal inflammation of mucous membranes of nasal passages and sinuses. Frequently, a catarrhal conjunctivitis and subcutaneous edema of face and wattles occur. DIAGNOSIS Isolation and Identification of Causative Agent PCR 2 BY:asst.prof.Dr.firas AL-bawi Differential Diagnosis Chronic respiratory disease, chronic fowl cholera, fowl pox, swollen head syndrome and A-vitaminosis INTERVENTION STRATEGIES Management Procedures Vaccination TREATMENT Sulfonamides and antibiotics are useful in alleviating the severity and course of IC . Erythromycin and oxytetracycline are two commonly used antibiotics. 3