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Integumentary System Skin = Integument Skin Skin has 7 functions Protective Covering. Regulates body temperature. Manufactures Vitamin D. Sensory Function (touch, pressure, etc.) Temporary storage of fat, glucose, water and salts. Screens out harmful ultraviolet radiation. Absorbs certain drugs. Layers of Skin 2 basic layers (Epidermis and Dermis) Epidermis Outermost covering Epithelial cells Avascular Stratum Corneum = outermost layer of epidermis. Stratum Germinativum = innermost layer of epidermis http://www.nku.edu/~dempseyd/SKIN.htm Stratum Corneum Outermost layer of epidermis Cytoplasm inside cells is replaced with keratin, keratin makes the cells waterproof. Cells are flat and flake off. First line of defense against surface bacteria. Thick on hands & feet. Stratum Germinativum Innermost epidermal layer. Reproductive layer = new cells grow and push their way up, then become keratinized, and replace the top layer which flakes off. Contains melanocytes = cells that contain pigment (melanin). Ridges in stratum germinativum arise from the dermis, these ridges are called Papillae. Melanin Pigment color depends on racial origin. The more melanin, the darker the skin. Freckles = patches of melanin. Albinism = no melanin. Sunlight stimulates melanocytes to make more melanin. Most skin cancer caused by sun (UV) exposure. Papillae Ridges that arise from the dermis create ridges in the epidermis = Papillae. Permanent ridges are present on fingers, palms of the hands, and soles of the feet. Finger prints = friction ridges = grip Dermis Thick True skin Connective tissue Vascular Contains : Blood vessels, nerve endings (sensory), muscles, hair follicles, oil and sweat glands, and fat cells (adipose tissue). Subcutaneous Layer Lies under the dermis Not really part of the Integumentary system. Made up of loose connective tissue. Contains half of the body’s stored fat. Appendages of the Skin Hair Outer layer = Cortex Inner layer = Medulla Part under the skin = Root Part outside the skin = Shaft (part we see) Pocket that holds hair = Follicle Tissue in root that contains capillaries = Papilla Alopecia Baldness. Normal hair replaced with fine almost transparent hair. Appendages of Skin Nails Nail is formed in the nail bed or MATRIX. Epidermal cells fuse together and fill with KERATIN. Sweat Glands (Sudoriferous Glands) Perspiration is 99% water. All over skins surface but large #s are present under the arms, palms of the hands, soles of the feet, and forehead. Duct extends from the dermis to the epidermis and forms a pore in the skin. May be activated by heat, pain, fever, and nervousness. Average fluid loss is 500ml per day. Oil Glands (Sebaceous Glands) Secrete oil (Sebum). Protects and lubricates the skin and hair. Glands usually located with a hair follicle. Arrector Pili Muscle Smooth muscle attached to hair follicle Arrector Pili muscle pulls on follicle causing hair to move. Bumps or Goose Bumps are seen on the skin. Purpose is to trap a layer of warm air around the body. Skin and Microorganisms Intact skin = best protection against pathogens, toxins, and water loss. Skin generally too dry for microbial growth, except for moist places. Most skin bacteria associated with hair follicles or sudoriferous glands. Perspiration odor caused by bacteria. The best way to prevent the spread of disease is by hand washing. Handwashing http://www.scrubclub.org/site/meet.aspx http://www.cdc.gov/CDCTV/HandsTogether/ Disorders of the Skin Acne Common, sometimes chronic, disorder of sebaceous glands. Sebum (oil) plugs pore, sometimes bacteria grows, then area fills with leukocytes (WBC) in an effort to clear plug and/or bacteria. Athlete’s Foot Contagious fungal infection. Usually contracted in public baths, and showers. Need antifungal medication to cure athlete’s foot. Dermatitis Non-Specific inflammation of the skin. Rash – reaction to soap, lotions, plants etc. Blotches – can be caused by emotional stress. Genital Herpes Viral = virus causes genital herpes. Blisters appear in genital area. Periods of remission and exacerbation. Spread through sexual contact. Can be passed to newborn during vaginal birth. May need C-Section. Acyclovir may help decrease outbreaks and length of each outbreak. Video Skin Cancer Most common type of cancer. Main cause is exposure to sun (UV rays). Example: Basal Cell Carcinoma (below). Video Malignant Melanoma Occurs in melanocytes. Appears as a brown, or black, irregular patch. A change in an existing wart or mole may indicate melanoma. Metastasizes to other areas quickly. Must surgically remove area & do chemotherapy. Melanoma Burns Caused by radiation, sun, boiling water, chemicals, fire, or electricity. Rule of Nines = measures % of body burned. Body is divided into 11 areas, and each is 9% of body surface. First Degree Burns Superficial. Skin red and dry. Involves only epidermis. Apply cold water, wound should heal within one week. Second Degree Burn Involves epidermis and dermis. Pain, swelling, redness, and blistering May be exposed to infection due to broken skin. Give pain medication, apply a dry sterile dressing. Heals within 2 weeks. Third Degree Burn Epidermis, dermis, and subcutaneous layers involved. Blackened skin, areas of skin may be totally gone. May be life threatening. Need to seek medical attention. The End Integumentary System Allied Health I