Download G – Responsible Teaching Staff

G – Responsible Teaching Staff
Name of University/ University of South Bohemia (USB), České Faculty of Science
Budějovice
Faculty
Name of Field of Study
First Name, Surname
Erik De Clercq
Academic titles Professor, M.D.,
Ph.D.
Contract
expires on
1941 Type and extent of contract
at University
Lecturer
Supervisor
Member of Programme Board
Other current employers
Type of contract
Extent of contract
Year of birth
Catholic University Leuven, Rega Institute for Medical Research, emeritus since 2006
Belgium
´Visiting Profesor´ since 2007 and ´Honorary Doctor´ at USB in
2009
Lectures in subjects of the relevant study programme
´Biochemistry at the Service of Medicine´
Field of university study and work experience since graduation
M.D.: Catholic University Leuven, Faculty of Medicine, 1966 (Summa Cum Laude); Ph.D.: Catholic University
Leuven, Rega Institute for Medical Research, 1972; Postdoctoral fellow: Stanford University, U.S.A., 1968-1970;
Catholic University Medical School Leuven; Rega Institute for Medical Research, (1972–present); Associate Profesor
(1972); profesor (1975); Full Profesor (1977); Director (1985-2006); Head of the Laboratory of Virology and
Chemotherapy (1970-2006); President of the Rega Foundation (1985-2011); Royal Academy of Medicine, Belgium ,
Fellow, Director (2006-2009); International Society for Antiviral Research, Founder of the Society, President (19901992)
Research topics: Chemotherapy of virus infections; Chemotherapy of AIDS; Chemotherapy of malignant diseases;
Molecular mechanism of action of antiviral and antitumor agents; Enzyme targets for antiviral and antitumor agents;
Nucleoside and nucleotide analogues; Reverse transcriptase inhibitors ; Virus adsorption, fusion and uncoating
inhibitors
List of salient publications over 5 past years
Till present, more than 2,500 scientific publications/articles published; altogether 95 of those are best recognized as
published in Nature or Science as well as in PNAS, J. Virol., Cancer Res., Mol. Pharmacol., etc.; since 1981 appointed
as member of 32 editorial boards of the top-ranking scientific journals.
A selected list of the salient publications over past 5 years follows (of several tens of publications yearly):
De Clercq E. (2011). A 40-year journey in search of selective antiviral chemotherapy. Annual Review of Pharmacology
and Toxicology 51: 1-24; De Clercq E. (2010). The next ten stories on antiviral drug discovery (Part E): Advents,
Advances, and Adventures. Medicinal Research Review 31: 118-160; De Clercq E. (2009). Antiviral drug discovery:
ten more compounds, ten more stories. Medicinal Research Review 29: 571-610; De Clercq E. (2009). Looking back in
2009 at the dawning of antiviral therapy now 50 years ago: an historical perspective. Advances in Virus Research 73: 253; Pannecouque, C., Daelemans, D., De Clercq, E. (2008). Tetrazolium-based colorimetric assay for the detection of
HIV replication inhibitors: revisited 20 years later. Nature Protocols, 3: 427-34; De Clercq E. (2007). Acyclic
nucleoside phosphonates: past, present and future. Bridging chemistry to HIV, HBV, HCV, HPV, adeno-, and poxvirus
infections: the phosphonate bridge. Biochemical Pharmacology 73: 911-922.
Names of dissertation these supervised within 2007 – 2010 (year of defence)
2007, Co-promotor: A. Hantson; 2008, Co-promotor: A. De Palma; 2008, Co-promotor: Liesbeth Lenaerts
Work experience abroad
Stanford University, U.S.A., postdoctoral fellow 1968-1970; Institute of Virology CSAS, 1971; Institute of Organic
Chemistry and Biochemistry ASCR, 1976 – present (Prof. A. Holý); Gilead Sciences, CA, U.S.A; many other research
collaborations
Academic/
Scientific
title Professor; Medical Biochemistry/Virology
at (university)
Honorary Doctor´s degree at several Catholic University
gained in the field of
universities
(Ghent,
Athens,
Ferrara,
Cited reference index
Shandong, Prague, USB, Tours).
1975
Written agreement to working I agree.
in the field
Signature:
in (year)
Abroad
> 20,000 for the
last ten years
Date
3. 6. 2011
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