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Review of Basic Principles in Optics, Wavefront and Wavefront Error Austin Roorda, Ph.D. University of California, Berkeley Google my name to find copies of these slides for free use and distribution Geometrical Optics Relationships between pupil size, refractive error and blur Optics of the eye: Depth of Focus 2 mm 4 mm 6 mm Optics of the eye: Depth of Focus Focused behind retina In focus Focused in front of retina 2 mm 4 mm 6 mm Demonstration Role of Pupil Size and Defocus on Retinal Blur Draw a cross like this one on a page. Hold it so close that is it completely out of focus, then squint. You should see the horizontal line become clear. The line becomes clear because you have used your eyelids to make your effective pupil size smaller, thereby reducing the blur due to defocus on the retina image. Only the horizontal line appears clear because you have only reduced the blur in the horizontal direction. Computation of Geometrical Blur Size blur[mrad][]blur[minutes]3.44[]DpupilsizemmDpupilsizemm where D is the defocus in diopters Application of Blur Equation • 1 D defocus, 8 mm pupil produces 27.52 minute blur size ~ 0.5 degrees Physical Optics The Wavefront What is the Wavefront? parallel beam = plane wavefront converging beam = spherical wavefront What is the Wavefront? parallel beam = plane wavefront ideal wavefront defocused wavefront What is the Wavefront? parallel beam = plane wavefront ideal wavefront aberrated beam = irregular wavefront What is the Wavefront? diverging beam = spherical wavefront ideal wavefront aberrated beam = irregular wavefront The Wave Aberration What is the Wave Aberration? diverging beam = spherical wavefront wave aberration Wave Aberration: Defocus Wavefront Aberration mm (superior-inferior) 3 2 1 0 -1 -2 -3 -3 -2 -1 0 1 mm (right-left) 2 3 Wave Aberration: Coma Wavefront Aberration mm (superior-inferior) 3 2 1 0 -1 -2 -3 -3 -2 -1 0 1 mm (right-left) 2 3 Wave Aberration: All Terms Wavefront Aberration mm (superior-inferior) 3 2 1 0 -1 -2 -3 -3 -2 -1 0 1 mm (right-left) 2 3 Zernike Polynomials Wave Aberration Contour Map 2 mm (superior-inferior) 1.5 1 0.5 0 -0.5 -1 -1.5 -2 -2.5 -2 -1 0 1 mm (right-left) 2 Breakdown of Zernike Terms Zernike term Coefficient value (microns) -0.5 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 0 0.5 1 1.5 2 astig. defocus astig. trefoil coma coma trefoil 2nd order spherical aberration 4th order 3rd order 5th order The Point Spread Function The Point Spread Function, or PSF, is the image that an optical system forms of a point source. The point source is the most fundamental object, and forms the basis for any complex object. The PSF is analogous to the Impulse Response Function in electronics. The Point Spread Function The PSF for a perfect optical system is the Airy disc, which is the Fraunhofer diffraction pattern for a circular pupil. Airy Disc 1.22aλθ⋅= Airy Disk angle subtended at the nodal point wavelength of the light pupil diameteraθλ≡≡≡ θ As the pupil size gets larger, the Airy disc gets smaller. PSF Airy Disk radius (minutes) angle subtended at the nodal point wavelength of the 2.5 2 1.5 1 0.5 0 1 2 3 4 5 pupil diameter (mm) 6 7 8 Point Spread Function vs. Pupil Size 1 mm 5 mm 2 mm 3 mm 6 mm 4 mm 7 mm Small Pupil Point Spread Function vs. Pupil Size 1 mm 2 mm 3 mm 4 mm Perfect Eye Typical Eye 5 mm 6 mm 7 mm Larger pupil Resolution Unresolved point sources Rayleigh resolution limit Resolved As the pupil size gets larger, the Airy disc gets smaller. PSF Airy Disk radius (minutes) minmin angle subtended at the nodal point wavelength o 2.5 2 1.5 1 0.5 0 1 2 3 4 5 pupil diameter (mm) 6 7 8 Keck telescope: (10 m reflector) About 4500 times better than the eye! Convolution Convolution (,) (,) (,)PSFxyOxyIxy⊗= Simulated Images 20/20 letters 20/40 letters MTF Modulation Transfer Function low medium object: 100% contrast contrast image 1 0 spatial frequency high MTF: Cutoff Frequency 1 mm 2 mm 4 mm 6 mm 8 mm modulation transfer 1 0.5 cut-off frequency 57.3 cutoffafλ=⋅ Rule of thumb: cutoff frequency increases by ~30 c/d for each mm increase in pupil size 0 0 50 100 150 200 250 spatial frequency (c/deg) 300 Modulation Transfer Function 0.8 0.6 0.4 0.2 vertical spatial frequency (c/d) horizontal spatial frequency (c/d) -100 0 c/deg 100 PTF Phase Transfer Function low medium object phase shift image 180 0 -180 spatial frequency high Phase Transfer Function • Contains information about asymmetry in the PSF • Contains information about contrast reversals (spurious resolution) Relationships Between Wave Aberration, PSF and MTF The PSF is the Fourier Transform (FT) of the pupil function ()2(,),(,)iWxyiiPSFxyFTPxyeπλ−= The MTF is the amplitude component of the FT of the PSF (){},(,) MTFffAmplitudeFTPSFxy= xyii The PTF is the phase component of the FT of the PSF (){},(,) PTFffPhaseFTPSFxy= xyii The OTF (MTF and PTF) can also be computed as the autocorrelation of the pupil function Point Spread Function Wavefront Aberration 0.5 0 -0.5 -2 -1 0 1 mm (right-left) Modulation Transfer Function 2 -200 -100 Phase Transfer Function 0.8 0.5 0.6 0 0.4 -0.5 0.2 -100 0 c/deg 100 -100 0 c/deg 100 0 100 arcsec 200 Point Spread Function Wavefront Aberration 0.5 0 -0.5 -2 -1 0 1 mm (right-left) Modulation Transfer Function 2 -200 -100 Phase Transfer Function 150 0.8 100 50 0.6 0 0.4 -50 -100 0.2 -150 -100 0 c/deg 100 -100 0 c/deg 100 0 100 arcsec 200 Point Spread Function Wavefront Aberration 1.5 1 0.5 0 -0.5 -2 -1 0 1 mm (right-left) Modulation Transfer Function 2 -1000 -500 Phase Transfer Function 150 0.8 100 50 0.6 0 0.4 -50 -100 0.2 -150 -100 0 c/deg 100 -100 0 c/deg 100 0 500 1000 arcsec Conventional Metrics to Define Imagine Quality ()()() Root Mean Square ()()21,, pupil area, wave aberration, avera Root Mean Square: Advantage of Using Zernikes to Represent the Wavefront te rm as tig m at is m .......RMSZZZZ−−=+++ 222220212223 de fo cu s as te tig rm m at is m te rm tre fo il te rm ()()()() …… Strehl Ratio diffraction-limited PSF Strehl Ratio = eyedlHH Hdl actual PSF Heye contrast Modulation Transfer Function 1 0.9 0.8 0.7 0.6 0.5 0.4 0.3 0.2 0.1 0 20/20 20/10 Area under the MTF 0 50 100 spatial frequency (c/deg) 150 Metrics to Define Image Quality Other Metrics Campbell,C.E. (2004). Improving visual function diagnostic metrics with the use of higher-order aberration information from the eye. J.Refract.Surg. 20, S495-S503 Cheng,X., Bradley,A., Hong,X., & Thibos,L. (2003). Relationship between refractive error and monochromatic aberrations of the eye. Optom.Vis.Sci. 80, 43-49. Cheng,X., Bradley,A., & Thibos,L.N. (2004). Predicting subjective judgment of best focus with objective image quality metrics. J.Vis. 4, 310-321. Guirao,A. & Williams,D.R. (2003). A method to predict refractive errors from wave aberration data. Optom.Vis.Sci. 80, 36-42. Marsack,J.D., Thibos,L.N., & Applegate,R.A. (2003). Scalar metrics of optical quality derived from wave aberrations predict visual performanc. J.Vis. 4, 322-328. Sarver,E.J. & Applegate,R.A. (2004). The importance of the phase transfer function to visual function and visual quality metrics. J.Refract.Surg. 20, S504-S507 Typical Values for Wave Aberration Strehl Ratio • Strehl ratios are about 5% for a 5 mm pupil that has been corrected for defocus and astigmatism. • Strehl ratios for small (~ 1 mm) pupils approach 1, but the image quality is poor due to diffraction. Typical Values for Wave Aberration Population Statistics trefoil coma coma trefoil spherical aberration Typical Values for Wave Aberration Change in aberrations with pupil size rms wave aberration (microns) 1.2 Shack Hartmann Methods Other Methods 1 Iglesias et al, 1998 Navarro et al, 1998 Liang et al, 1994 Liang and Williams, 1997 Liang et al, 1997 Walsh et al, 1984 He et al, 1999 Calver et al, 1999 Calver et al, 1999 Porter et al., 2001 He et al, 2002 He et al, 2002 Xu et al, 2003 Paquin et al, 2002 Paquin et al, 2002 Carkeet et al, 2002 Cheng et al, 2004 0.8 0.6 0.4 0.2 0 0 1 2 3 4 5 6 7 pupil size (mm) 8 9 Typical Values for Wave Aberration Change in aberrations with age Monochromatic Aberrations as a Function of Age, from Childhood to Advanced Age Isabelle Brunette,1 Juan M. Bueno,2 Mireille Parent,1,3 Habib Hamam,3 and Pierre Simonet3 Other Optical Factors that Degrade Image Quality Retinal Sampling Sampling by Foveal Cones Projected Image 20/20 letter Sampled Image 5 arc minutes Sampling by Foveal Cones Projected Image 20/5 letter Sampled Image 5 arc minutes Nyquist Sampling Theorem Photoreceptor Sampling >> Spatial Frequency 1 I 0 1 I 0 nearly 100% transmitted Photoreceptor Sampling = 2 x Spatial Frequency 1 I 0 1 I 0 nearly 100% transmitted Photoreceptor Sampling = Spatial Frequency 1 I 0 1 I 0 nothing transmitted Nyquist theorem: The maximum spatial frequency that can be detected is equal to _ of the sampling frequency. foveal cone spacing ~ 120 samples/deg maximum spatial frequency: 60 cycles/deg (20/10 or 6/3 acuity) MTF: Cutoff Frequency cut-off frequency 57.3 cutoffafλ=⋅ Nyquist limit 1 mm 2 mm 4 mm 6 mm 8 mm modulation transfer 1 0.5 Rule of thumb: cutoff frequency increases by ~30 c/d for each mm increase in pupil size 0 0 50 100 150 200 250 spatial frequency (c/deg) 300 Thankyou!