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Global TB Drug Facility “Securing timely access to quality, affordable TB drugs” What services does the GDF provide? ACCESS: • Grant Service for first-line anti-TB drugs for countries for some or all of their drug supply and wish to expand or strengthen their DOTS programmes. • Direct Procurement Service for countries, NGOs and donors to buy first- or second-line anti-TB drugs for use in DOTS programmes; RATIONAL USE: • Facilitator of Rational Use of TB medicines GDF as Rational Use facilitator • Standardization • FDC tablets • Blister sheets of 7 x 4 tablets • Patient kits • Pediatric formulations • Quantification tool GDF as Rational Use facilitator Standardization • Only medicines for WHO recommended regimens • 10 first line products: – 5 FDCs – 3 single formulations – Streptomycin and for Injections • 8 second line products GDF as Rational Use facilitator FDC tablets • Patients: less tablets to take • Improved adherence • Reduces development of MDR TB • Same No. of tablets throughout intensive and continuation phases of treatment GDF as Rational Use facilitator GDF designed blister cards • 1 card: 4 rows of 7 = 28 tablets • Based on dosing schemes of 28 dose per month • Regardless patients takes 2, 3, 4 or 5 tabs p.dose: • Always full blister cards used for intensive as well as for continuation phase of Tr. GDF as Rational Use facilitator Stop TB Patient kits Stop TB Patient Kits Full treatment for one patient in the middle weight band (40 to 54 kg) For patients in the • lower (30-39 kg) or higher (55-70 kg) weight bands and beyond • the health worker will adjust the number of blisters at the beginning of treatment Every kit is personalised for the patient by writing name, address, body weight and treatment register number on the outside of the kit: GDF as Rational Use facilitator Quantification tool (Excel based) calculate country wide TB drug requirements: • Regimens, • No. of patients / regimen • Present stocks, • Buffer stocks, • Stock-out dates / required dates of delivery • Quantities per item • Cost per item / total cost Thank you for your support to the GDF! http://www.stoptb.org/gdf/