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Pharmacology model 2
Student: abu baker
Course :3
Group :17
Faculty:M
( Subject )
1-cardiac glycosides . antiarrhythmic drug
2-antianginal drugs
3-hypertensive and antihypertensive drug .diuretics
4-respiratory system drug
5-GIT drug
6-haemopoisis, haemostasis and blood drug
8-hormonel and protein drug
9-anti- inflammatory antiallergic
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1-cardiac glycosides . antiarrhythmic drug (10 drug )
1-Amiodarone : antiarrhythmic , k+ channel blocker
Uses :supraventricular , ventricular tachyarrhythmia,extra systole
2-Corgylconum: short action cardiac glycosides
Uses : chronic heaert failure , supraventricular tachyarrhythmia
3-Digoxin : intermediate action , cardiac glycosides
Uses : chronic heaert failure , supraventricular tachyarrhythmia
4-Lodoccaine : local anesthetic , amide
Uses : local anesthetic , during operation
5-Metoprolo : neurotropic agent ,drug decreasing vasomotor cener
activity (centrally acting sympatholytics )
Uses : hypertension with supraventricular tachyarrhythmia,
previous myocardial infraction , angina pectoris , glaucoma,
migraine headache
6-Procainamide : anti-arrhythmic ,membrane stablising agent
(Na+ channels blocker )
Uses: supraventricular , ventricular tachyarrhythmia, wolfparkinson – white syndrome by prolonging the refractory period of
the accessory pathway , typically use is secondary to lidocaine in
patients who are allergic to lodocaine .
7-Propanolol : sympatholytic non- selective beta bloker (beta 1.2)
Uses : angina pectoris , migraine, myocardial infraction ,
hypertension , tachyarrthmyia
8-Strophanthin : cardiac glycosides
Uses: acute heart failure , chronic heart failure III stage,
supraventricular paroxysmal tachycardia .
9-Verapamil: anti-arrhythmic , (Ca+ channels blocker )
Uses : supraventricular arrhythmia, fibrillation, paroxysmal
tachycardia , hypertention, angina.
10-Lovastatin : cholesterol lowering agent
Uses: MI,unstable angina,CHD,hypercholesterolemia
2-antianginal drugs(5 drug)
11-Isosorbite dinitrate :osmotic diuretic
Uses : prophylaxis and prevention of angina attack, decrease
pulmonary stasis in cardiac insufficiency .
12-Nitroglycerin : antinational , nitroglycerin
Uses : prophylaxis and control of angina attack, iv infusions in
myocardial infraction , lead to decrease infraction zone due to
reduce of left ventricular blood pressure, decrease of pulmonary
stasis in cardiac insufficiency
13-Nifedipine: calcium channel blocker, anti-anginal
Uses: prophylaxis, treatment angina, hypertension .
14-Nicergoline:nootropic drug,cerebrovascular drug
Uses:memory disturbances,mood changes, senile dermentia.
15-Nicotinic acid: nootropic drug,anti-oxidants drug
Uses: memory disturbances,mood changes, senile dermentia.
3-hypertensive and antihypertensive drug .diuretics(9drug)
16-Furosemide : diuretics ,antihypertensive
Uses : hypertension , edam, congestive heart failure,
hypercalcemia ,cirrhosis .
17-Hydrochlorothiazide: Thiazide derivative, diuretic
Uses : hypertension , edam, congestive heart failure, renal tubular
acidosis,prevent kidney stone, osteoporsis
18-Spironoloctone :anti-hypertensive drug , aldostrone
antagonists
Uses : , edam, congestive heart failure, action potential of other
hypotensive drug, ascites in liver, malignant ascites , primary
hyperaldosterism
19-Enalapril : ACE-inhibitors,(ACE-angiotensin converting
enzyme)
Uses: hypertension with chronic congestive heart failure .
20-Prazosin : selective alpa-1 adrenoblocker
Uses : hypertention , migraine , raynauds, benign prostate
hypertension, diagnostic and treatment of pheochromotoma
21-Minoxidil:hypotensive action of potassium channel activators,
myptropic vasodilators
Uses : hypertension , prophylaxis and treatment angina, in IV
injection rapidly act and control hypertensive crisis
22-Reserpine:neurotropic agent,adrenergic neuron blocking
agents
Uses:hypertension,dyskinesia
23-Dobutamine:beta 1 adrenomimetic
Uses:congestive heart frailer,septic cardiovascular shock
24-Acetazolamide:carbonic-anhydrase inhibitor ,dirutic
Uses:glaucoma,acute motion sikness,eilepsy
4-respiratory system drug(5drug)
25-Aethiminizolum: respiratory stimulant , directly action on
respiratory center
Uses : stimulant of respiration in overdosage and poisoning with
narcotic drug ( e.g alcohol )
26-Oxeladine : respiration stimulants , centrally action non-opioid
Uses : spasmodic cough ,
27-Salbutamol : beta-adrenomimetics ,selective, short action
Uses : bronchial asthma, in danger of pregnancy interruption .
28-Codeine: opioid,centrally acting,antitussive
Uses: dry or painful cough.
29-Bromhexine: mucolytic
Uses: acute and chronic tracheitis ,chronic obstructive
bronchiectasis ,chronic asthma .
5-GIT drug (14 drug)
30-Famotidine : H2 histamine receptor blocker, suppressor of
gastric secretion
Uses : hyperacid and erosive gastritis, gastric and duodenal ulcer ,
peptic esophagitis
31-Omeprazole : drug that decrease gastric gland secretion,
inhibitor of proton pump .
Uses : hyperacid and erosive gastritis, gastric and duodenal ulcer ,
peptic esophagitis
32-Pirenzepine : drug decrease gastric gland secretion,selective
Uses : hyperacid and erosive gastritis, gastric and duodenal ulcer ,
peptic esophagitis
33-Sodium bicarbonate : drug influencing on the fluid-electrolyte
and acid base balance
Uses: isotonic solution, dehydration forced dieresis, to dissolve
other drug
34-Colloidal bismuth subcitrate : covering agent,
gastroprotectors
Uses: gastric and duodenal ulcer, upset stomach
35-Colestipol : resin, interfering with intestinal absorption of lipid
Uses : hyperlipidemia of 1 type
36-Metoclopramide : anti-emetic
Uses : vomiting induces by irritation of GI mucous, vomiting with
central origin, post operative period, pregnancy toxicosis, radiation
sickness.
37-Misoprostole : prostaglandins,drug decreasing gastric gland
secrtion
Uses: preventing of ulcerogenous of NSAIDs
38-Unithiolum : antidote
Uses: poisoning in arsenic mercury,chromium,bismuth and other
metals with thiol poisons ,hepatocerebral dystrophy
39-Pancreatin: enzymes,enhancing digestion
Uses: pancreatitis,digestive disturbances,achiia,hepatitis
40-Allocholum:cholescretics agent promoting bile secrtion
Uses:chronic hepatitis,cholecystitis,cholelithic disease
41-Bisacodii:cotact purgative,increasing motility of intestine
Uses:relives constipation,during preparation for
colonoscopy,neuregic bowel dysfunction
42-Loperamide: synthetic piperidine derivative,opioid drug
Uses: gastroenteritis,inflammatory bowel disease
43-Papaverine:cholgolics (bile-expelling drug)
Uses:chronic hepatitis,cholangitis,cholecytitis,dyskinesia
6-haemopoisis, haemostasis and blood drug(12drug)
44-Warfarin: anti-cogulants, indirectly action
Uses: thrombosis,embolism,atrial fibrillation, the presence of
artificial heart valves, deep venous thrombosis ,pulmonary
embolism .
45-Heparin : directly action anticoagulant
Uses : prevent thrombus formation in MI, embolism, artificial
blood circulation in surgeries, hemodialysis .
46-Fraxiparin : directly action anticoagulant
Uses: prevent thrombus formation in MI, embolism, artificial
blood circulation in surgeries, hemodialysis
47-Ethamsylate: systemically action procoagulants promoting
haemostasis
Uses: prophylaxis,control haemorrhages from small blood vessels,
neonatal intraventricular haemorrhage, secondary bleeding due to
thrombocytopenia .
48-Ferrous sulphate :oral drug for iron deficient anemia
Uses: chronic hemorrhages , pregnancy, iron deficient anemia, iron
malabsorption
49-Ferrum-lek : same as ferrous sulphate
50-Dipyridamol : antiplatelet drug
Uses: thrombophlebitis , MI thrombo, embolism
prophylaxis,microcirculation disturbances .
51-Cyanocobalamin :B12 drug used in megaloblastic anemia
Uses: hyperchromic, pernicious, malignant,megaloblastic
(Addison-birmer disease) iron deficient, hypoplastic anemias,
radiation diseases, after operation,dystrophy,liver and nerve system
diseases.
52-Altepase : thrombolytic, fibrinolytic
Uses : lysis of thrombus (3 day old) thrombophblebitis ,thrombo
embolism, first hours after acute MI.
53-Folic acid : drug used in macrocytic anemia
Uses : macrocytic anemia,post operative anemia, pregnancyand
new born babies,radiation diseases drug therapy,interstinal
TB.prolonged ctrimazole therapy .
54-Methyluracilum: leucopoiesis dtimulators,non specific drug,
which stimulates nucleic acids synthesis .
Uses: alimentary and toxic aleukemia,agranulocytosis and
leucopenia,radiation skin damage ,fractures, ulcer
55-Ergometrine : ergot alkaloid,increasing uterine tone .
Uses: hypotonic and atonic uterine hemorrhage,prevents bleeding
after child birth.
8-hormonel and protein vitamin enzyme and
contraceptive drug (17drug)
56-Human menopausal gondotropin : anterior pituitary
hormones
Uses: infertility in women,hypogonadism ,hypospermia
57-Methyltestesterone propionate : gonadal hormone-androgens
Uses : hypogenitalism,impotence at males,climax, breast and
ovarian cancer(women before 60),dysmenorrheal, climacteric
disturbance.
58-Nandrolone derivative : anabolic steroids
Uses : cachexia,asthenia,radiation therapy,osteoporosis,bone
fractures, ischemic heart, prolong treatment with glucocortids
59-Oxytocine : pituitary hormone
Uses : weal labour, hypotonic metrorrhagias.
60-Tamoxifen citrate : steroid hormone and their antagonists
Uses : breast cancer, proctat cancer, lymphogranulotosis, chronic
lymphoid leucosis, lymphosaecoma
61-Metformin:anti-diabetic preparation,synthetic drug,biguanide
derivatives.
Uses:forms of diabetes mellitus in elderly (insulin-non-dependent
diabetes,resulting from sclerosis of insular apparatus of pancreas .
62-Regular insulin:anti diabetic drug,insulin preparations
Uses: improve glycemic control in adults and children with
diabetes mellitus .
63-Prednisolone: steroidal anti-inflammatory
drug.Glucocorticoids,
Intermediate action
Uses : replacement therapy in adrenal insufficiency, acute
hypotension .shock,heart arrest,collagenosis,rheumatism,
immunosuppression,inflammatory skin and mucosa diseases .
64-Tacopherol: vitamin E
Uses: premature labour,Alzheimers disease, cancer,catarats,
Glaucoma,heart disease,parkinsons disease, pregnancy,
65-Thiamine hydrochloride : vitamin B1
Uses:mosquito repellant, treatment of ulcerative colitis, chronic
diarrhea, cerebellar syndrome,polyneuritis, appetite stimulant .
66-Acidin-pepsin: drug for replacement therapy
Uses:pancreatitis,digestion disturbances,dyspepsia
67-Aprotinin (contrycal): drug of disturbance of pancreas
secretory function, acute pancreatitis
Uses : acute pancreatitis
68-Progesterone : gravidoprotector ,progestins
Uses:premature labour
69-Allopurinol : anti-enzymatic drug
Uses: radation therapy of tumors,massive glucocorticoid
therapy,propylaxis of gout and calcium oxalate and calcium renal
stone
.
70-Thymalinum:immunostimulator .biogenic
Uses :radation therapy,cancer
71-Marvelon: contraceptive pill,combind monoophasic
Uses:oral contraceptive
72-Dinoprost (pg 2):uterine relaxtion,decrease uterine cervix tone
Uses:induction of abortion,induction and augmentation of labour
9-anti- inflammatory antiallergic(8drug)
73-Celoxib: selective cox-2 inhibitors, sulfonamide derievative,
non-steroidal anti inflammatory drug .
Uses:osteoarthritis,rheumatoid arthritis,acute pain,painful
menstruation.
74-Cromolyn sodium : mast cell stabilizer,anti-llergic drug
Uses:prophylaxis of bronchial asthma attacks,allergic rhinitis,
Conjunctivitis .
75-Diclofenac sodium:Aryl-acetic acid derievative
Uses:collagenosis, rheumatism,lupus erythematosus, rheumatoid
polyarthritis .
76-Diphenhydramine(promedol):H1receptor blocker with
sedative effet anti-allergic
Uses:relif allergiy,hay fever,potentiate general anesthesia,urticaria
Vasomotor serum sickness
77-Ibrufen:non-selective cox inhibitor indole derievative
Uses same as (Diclofenac sodium)
78-Indomethacin: same as (Ibrufen)
79-Loratadin:H1histamine antagonist drug
Uses:relief allergy such hay fever (allergic rhinitis)urticaria(hives)
skin allergy, treat mild to moderate pain from headaches .
80-Vinpocetine:anti-iflammatory agent
Uses:parkinsons disease,alzheimers disease,nootropic for
improvement memory,motion sickness
Kharkov (2013)