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胡 朝 榮 醫 師 Chaur-Jong Hu M.D. 學歷: 台北醫學院醫學士 1990.6 現任: 台北醫學大學署立雙和醫院神經科主治醫師/副教授 2009.9-迄今 台北醫學大學署立雙和醫院教學研究部教學副主任 2008.8-迄今 台灣神經學會專科醫師 1993.8-迄今(理事 2011-2013) 台灣臨床失智症學會會員 2006.10-迄今(理事 2007-2014) 台灣腦中風醫學會會員 中華民國醫用超音波學會會員 台灣癲癇醫學會會員 台灣基礎神經學會會員 經歷: 台北市立仁愛醫院神經科主治醫師 1996.1-2004.12 美國聖路易華盛頓大學神經科研究員 2000.4-2001.3 台北市立仁愛醫院分子醫學科主任 2001.7-2004.12 高雄醫學大學神經科兼任講師 2002.8-2003.7 台北市立聯合醫院仁愛院區神經科主治醫師 2005.1-2005.7 台北市立聯合醫院教學研究部研究發展組主任 2005.1-2005.7 北市醫學雜誌, 台灣神經醫學會雜誌執行編輯 2005.1-2005.7 台北醫學大學神經科兼任主治醫師/講師 2004.8-2005.7 台北醫學大學神經科主治醫師/講師 2005.8-2007.8 台北醫學大學神經科主治醫師/助理教授 2007.8-2008.8 台北醫學大學附設醫院教學研究部教學副主任 2006.8-2008.7 台北醫學大學附設醫院實證醫學中心主任 2006.8-2008.7 著作: 期刊論文(PAPERS) : 1. Traumatic Brainstem Deafness with Normal Brainstem Auditory Evoked Potentials; Hu CJ, Chan KY, Lin TJ, Hsiao SH, Chang YM, Sung SM. Neurology 1997, 48:1448-51 (SCI) 2. Transcranial Magnetic Stimulation in Bells palsy; Hu CJ, Lin FZ, Sung SM. Acta Neurol Taiwan 1997,6:36-41 3. Association of apolipoprotein E genotype and intronic polymorphism of the presenilin-1 gene with Alzheimers disease in elderly Taiwan Chinese; Hu CJ, Sung SM, Liu HC, Chang JG. J Neurol Sci 1998, 157:158-161 (SCI) 4. Rapid detection of type 1A Charcot-Marie-Tooth (CMT1A) disease hotspot duplication by a PCR-based DNA test. Chang JG, Jong YJ, Wang WP, Wang JC, Hu CJ, Lo MC, Chang CP. Clin Chem 1998, 44:270-274 (SCI) 5. Central Pontine Myelinolysis Associated With Abnormal Magnetic Resonance Signals In Basal Ganglia. Wu Dean, Chang YM, Hu CJ. Acta Neurol Taiwan 1998, 7:119-1266. 6. No mutation of G209A in the -synuclein gene in sporadic Parkinson’s disease among Taiwan Chinese; Hu CJ, Sung SM, Liu HC, Chang JG. Eur Neurol 1999, 41:85-87 (SCI) 7. Prenatal Prediction of Spinal Muscular Atrophy of Chinese. Lin SP, Chang JG, Jong YJ, Yang TY, Tsai CH, Wang NM, Li H, Hsieh-Li HM, Hu CJ. Prenat Diagn 1999;19:657-661 (SCI) 8. A study of Audiometry in Patients with Abnormal Wave II of Brainstem Auditory Evoked potentials. Cheng CC, Hu CJ, Chang YM, Acta Neurol Taiwan, 1999; 7:272-2759. 9. No Association of Alpha-2 macroglobulin gene five-nucleotide deletion with AD in Taiwan Chinese; Hu CJ, Sung SM, Liu HC, Lee KY, Hsu WC, Wang WK, Lee CC, Tsai CH, Chang JG. Neurology 1999 53:642-643 (SCI) 10. Molecular analysis of secretor type (1,2)-Fucosyltransferase gene mutations in the Chinese and Thai populations. Chang JG, Yang TY, Liu TC, Lin TP, Hu CJ, Kao MC, Wang NM, Tsai FJ, Peng CT, Tsai CH. Transfusion 1999; 39: 1013-1017 (SCI) 11. Serotonin Syndrome: A Case Report and Literature Review. Chang WS, Hu CJ, Lin SA, Chang YM. Acta Neurol Taiwan 1999; 8:234-23712. 12. Genetic risk factors of sporadic Alzheimer's disease among Chinese in Taiwan. Hu CJ, Sung SM, Liu HC, Hsu WJ, Lee LS, Lee CC, Tsai CH, Chang JG. J Neurol Sci 2000; 181: 127-131. (SCI) 13. Polymorphisms of the Parkin Gene in Sporadic Pakinson’s Disease. Hu CJ, Sung SM, Liu HC, Lee CC, Tsai CH, Chang JG. Eur Neurol 2000, 44:90-93 (SCI) 14. Molecular Basis of Lewis Blood Type in Taiwanese. Liu TC, Lin SF, Yang TY, Perng LY, Jaung SJ, Hu CJ, Chang JG. Kaohsiung J Med Sci 2000;16:552-55815. 15. Reduction and Restoration of Mitochondrial DNA Content After Focal Cerebral Ischemia. eperfusion. Chen H #, Hu CJ #, He YY, Yang DI, Xu J, Hsu CY. Stroke 2001;32:2382-2387 (SCI) #co-first author 16. Molecular analysis of SMN, NAIP and P44 genes of SMA patients and their families. Tsai CH, Jong YJ, Hu CJ, Chen CM, Shih MC, Chang CP, Chang JG. J Neurol Sci 2001;190:35-40. (SCI) 17. The Association of Beta-site APP Cleaving Enzyme (BACE) C786G Polymorphism with Alzheimer’s Disease. Liu HC, Leu SJ, Chang JG, Sung SM, Hsu WC, Lee LS, Hu CJ *. Brain Res 2003;961:88-91. (SCI) *corresponding author 18. Tumor necrosis factor receptor 2 microsatellite and exon 6 polymorphisms in rheumatoid arthritis in Taiwan. Yen JH, Tsai WC, Chen CJ, Ou TT, Lin CH, Hu CJ, Liu HW. J Rheumatol 2003;30:438-42 (SCI) 19. Manganese superoxide dismutase and cytochrome P450 1A1 genes polymorphisms in rheumatoid arthritis in Taiwan. Yen JH, Chen CJ, Tsai WC, Lin CH, Ou TT, Hu CJ, Liu HW. Hum Immunol 2003;64:366-73 (SCI) 20. Cytochrome P450 1A1 and manganese superoxide dismutase genes polymorphisms in ankylosing spondylitis. Yen JH, Tsai WC, Chen CJ, Lin CH, Ou TT, Hu CJ, Liu HW.. Immunol Lett 2003;88:113-6. (SCI) 21. Association between apolipoprotein E genotype and outcome of traumatic brain injury. Chiang MF, Chang JG, Hu CJ. Acta Neurochir (Wien) 2003;145:649-54. (SCI) 22. Cytochrome P450 and manganese superoxide dismutase genes polymorphisms in systemic lupus erythematosus. Yen JH, Chen CJ, Tsai WC, Lin CH, Ou TT, Hu CJ, Liu HW. Immunol Lett 2003;90:19-24. (SCI) 23. Cytochrome P450 1A1 and manganese superoxide dismutase genes polymorphisms in reactive arthritis. Yen JH, Tsai WC, Lin CH, Ou TT, Hu CJ, Liu HW. Immunol Lett 2003; 90: 151-4. (SCI) 24. Polymorphisms of the Human Platelet Antigens and Coagulation Factor V Leiden are not Risk Factors for Stroke. Chang YM, Lee KY, Lee LS, Chang JG, Hu CJ *. Taipei City Medical Journal 2004, 1:142-149 *corresponding author 25. Cytochrome P450 1A1 and manganese superoxide dismutase gene polymorphisms in Behcet's disease. Yen JH, Tsai WC, Lin CH, Ou TT, Hu CJ, Liu HW. J Rheumatol 2004; 31:736-40. (SCI) 26. DAT polymorphism and diverse clinical manifestations in methamphetamine abusers. Liu HC, Lin SK, Liu SK, Chen SL, Hu CJ, Chang JG, Leu SJ. Psychiatr Genet 2004;14:33-7. (SCI)27. Cytochrome p450 1Al gene polymorphisms in patients with psoriatic arthritis. Yen JH, Tsai WC, Lin CH, Ou TT, Hu CJ, Liu HW. Scand J Rheumatol 2004;33:19-23. (SCI) 28. Aspirin inhibits monocyte chemoattractant protein-1 and interleukin-8 expression in TNF-alpha stimulated human umbilical vein endothelial cells. Yang YY#, Hu CJ#, Chang SM, Tai TY, Leu SJ. Atherosclerosis. 2004;174:207-13. #co-first author (SCI) 29. Manganese superoxide dismutase gene polymorphisms in psoriatic arthritis. Yen JH, Tsai WC, Lin CH, Ou TT, Hu CJ, Liu HW. Dis Markers 2003-2004;19:263-5. (SCI) 30. The Association of Folate, Vitamin B6, B12, and Homocysteine Blood Levels with Ischemic Stroke. Chang WS, Cheng CC, Wei IL, Chen PL, Chang YM, Hu CJ *. Taipei City Medical Journal 2004, 1:321-417 *corresponding author 31. Association of Neprilysin-like 2 (MMEL2) Polymorphisms with Alzheimer’ s Disease. Liu HC, Leu SJ, Chang JG, Sung SM, Hsu WC, Lee LS, Hu CJ *. Taipei City Medical Journal 2004, 1:418-425 *corresponding author 32. Assessment of synthetic peptides of severe acute respiratory syndrome coronavirus recognized by long-lasting immunity. Shichijo S, Keicho N, Long HT, Quy T, Phi NC, Ha LD, Ban VV, Itoyama S, Hu CJ, Komatsu N, Kirikae T, Kirikae F, Shirasawa S, Kaji M, Fukuda T, Sata M, Kuratsuji T, Itoh K, Sasazuki T. Tissue Antigens 2004;64:600-7. (SCI) 33. Relationship between vertebral bone marrow blood perfusion and common carotid intima-media thickness in aging adults. Chen WT, Ting-Fang Shih T, Hu CJ, Chen RC, Tu HY. J Magn Reson Imaging 2004; 20:811-816 (SCI) 34. Toll-like receptor 4 gene C119A but not Asp299Gly polymorphism is associated with ischemic stroke among Chinese in Taiwan. Lin YC, Chang YM, Yu JM, Yen JH, Chang JG, Hu CJ *. Atherosclerosis 2005;180:305-9. (SCI) *corresponding author 35. Infrared thermography to mass-screen suspected SARS patients with fever. Chiu WT, Lin PW, Chiou HY, Lee WS, Lee CN, Yang YY, Lee HM, Hsieh MS, Hu CJ, Ho YS, Deng WP, Hsu CY. Asia Pac J Public Health. 2005;17:26-8. (SCI) 36. Pravastatin Attenuates Ceramide-Induced Cytotoxicity in Mouse Cerebral Endothelial Cells with HIF-1 Activation and VEGF Upregulation. Chen SD, Hu CJ, Yang DI, Nassief A, Chen H, Yin K, Xu J, Hsu CY, Ann N Y Acad Sci 2005;1042:357-364. (SCI) 37. Natural resistance-associated macrophage protein 1 gene polymorphisms in rheumatoid arthritis. Yen JH, Lin CH, Tsai WC, Ou TT, Wu CC, Hu CJ, Liu HW. Immunol Lett 2006;102:91-7. (SCI) 38. Proteomic Identification of Lower Apolipoprotein A-I in Alzheimer's Disease. Liu HC#, Hu CJ#, Chang JG, Sung SM, Lee LS, Yuan RY, Leu SJ. Dement Geriatr Cogn Disord. 2006;21:155-161 #co-first author (SCI) 39. A Left MCA Territory Infarction During Intravenous Recombinant Tissue Plasminogen Activator Therapy for Right MCA Territory Ischemic Stroke. Lai CC, Hu CJ *. Emerg Med J 2006; 23:e11. *corresponding author (SCI) 40. A novel compound heterozygous mutation of K494_V495 deletion plus R496L and D487_F489 deletion in extreme C-terminus of cytochrome P450c17 causes 17alpha-hydroxylase deficiency. Lee LS, Shu WJ, Wu CM, Hsieh CH, Chen SM, Hu CJ, Chen WY, Chung BC. Mol Cell Endocrinol. 2006; 249:16-20. (SCI) 41. Promoter Region Methylation and Reduced Expression of Thrombospondin-1 after Oxygen-Glucose Deprivation in Murine Cerebral Endothelial Cells. Hu CJ, Chen SD, Yang DI, Lin TN, Chen CM, Huang T HM, Hsu CY. J Cereb Blood Flow Metab. 2006;26:1519-26 (SCI) 42. Killer cell immunoglobulin-like receptor gene's repertoire in rheumatoid arthritis. Scand J Rheumatol. Yen JH, Lin CH, Tsai WC, Wu CC, Ou TT, Hu CJ, Liu HW. 2006;35:124-7. (SCI) 43. Segmental study of the median nerve versus comparative tests in the diagnosis of mild carpal tunnel syndrome. Sheu JJ, Yuan RY, Chiou HY, Hu CJ, Chen WT. Clin Neurophysiol. 2006, 117:1249-55. (SCI) 44. The genetic studies of dementias in Taiwan. Chen HH, Hu CJ*. Acta Neurol Taiwan. 2006;15:60-3. *corresponding author 45. Genetic Characteristics of Dementia in Taiwanese. Chen HH, Hu CJ*. Acta Neurol Taiwan. 2006;15:161-169. *corresponding author 46. Association between Polymorphisms of ACE, B2AR, ANP, ENOS and Cardiovascular Diseases: a Community Based Study in Matsu Area. Hu CJ, Wang CH, Lee JH, Hsieh CM, Cheng CC, Chang CJ. Clin Chem Lab Med 2007;45:20-5. (SCI) 47. Chicken single-chain variable fragments against the SARS-CoV spike protein. Lee YC, Leu SJ, Hu CJ, Shih NY, Huang IJ, Wu HH, Hsieh WS, Chiang BL, Chiu WT, Yang YY. J Virol Methods 2007;146:104-11. (SCI) 48. Ligands for programmed cell death 1 gene in patients with systemic lupus erythematosus. Wang SC, Lin CH, Ou TT, Wu CC, Tsai WC, Hu CJ, Liu HW, Yen JH. J Rheumatol 2007;34:721-5. (SCI) 49. A pilot study for circadian gene disturbance in dementia patients. Liu HC#, Hu CJ#, Tang YC, Chang JG. Neurosci Lett 2008;435:229-33. #co-first author (SCI) 50. Increased risk of stroke in patients who undergo cesarean section delivery: a nationwide population-based study. Lin SY, Hu CJ, Lin HC. Am J Obstet Gynecol 2008;198:391.e1-7.51. 51. Weekly pattern of stroke onset in an Asian country: a nationwide population-based study. Lin HC, Lin SY, Lee HC, Hu CJ, Choy CS. Chronobiol Int 2008;25:788-99. (SCI) 52. Seasonal variation in ischemic stroke incidence and association with climate: a six-year population-based study. Lee HC, Hu CJ, Chen CS, Lin HC. Chronobiol Int 2008;25:938-49. (SCI) 53. The epigenetic effects of amyloid-beta (1-40) on global DNA and neprilysin genes in murine cerebral endothelial cells. Chen KL, Wang SS, Yang YY, Yuan RY, Chen RM, Hu CJ*. Biochem Biophys Res Commun 2009;378:57-61. (SCI) *corresponding author 54. Botulinum Toxin for Diabetic Neuropathic Pain: A Randomized Double-Blind Cross-over Trial. Yuan RY, Sheu JJ, Yu JM, Chen WT, Tseng IJ, Chang HH, Hu CJ *. Neurology. 2009;72:1473-8. (SCI) *corresponding author 55. Low Sleep Efficiency in Patients with Cognitive Impairment. Yu JM, Tseng IJ, Yuan RY, Sheu JJ, Liu HC, Hu CJ*. Acta Neurol Taiwan. 2009;18:91-7. *corresponding author 56. Methylenetetrahydrofolate reductase polymorphisms and plasma homocysteine in levodopa-treated and non-treated Parkinson's disease patients. Yuan RY, Sheu JJ, Yu JM, Hu CJ, Tseng IJ, Ho CS, Yeh CY, Hung YL, Chiang TR. J Neurol Sci 2009;287:64-8 (SCI) 57. Reduction of Monocyte Chemoattractant Protein-1 and Interleukin-8 Levels by Ticlopidine in TNF-alpha Stimulated Human Umbilical Vein Endothelial Cells. Hu CJ, Yang YY, Shih NY, Tsai YH, Lee YL, Tseng H, Dai YS, Chang SM, Liu CY, Leu SJ. J Biomed Biotechnol 2009:917837 (SCI) 58. Botulinum toxin for diabetic neuropathic pain: a randomized double-blind crossover trial: botulinum toxin for neuropathic pain? Torgovnick J, Arsura E, Sethi NK, Hu CJ, Yuan RY, Sheu JJ, Apfel SC. Neurology. 2010;74:92; author reply 59. An increased risk of stroke among panic disorder patients: a 3-year follow-up study. Chen YH, Hu CJ, Lee HC, Lin HC. Can J Psychiatry. 2010;55:43-9. (SCI) 60. A highly sensitive peptide substrate for detecting two Abeta-degrading enzymes: neprilysin and insulin-degrading enzyme. Chen PT, Liao TY, Hu CJ, Wu ST, Wang SS, Chen RP. J Neurosci Methods. 2010;190:57-62. (SCI) 61. Expression of inducible nitric oxide synthase (iNOS) and period 1 (PER1) clock gene products in different sleep stages of patients with cognitive impairment. Tseng IJ, Liu HC, Yuan RY, Sheu JJ, Yu JM, Hu CJ*, J Clin Neurosci 2010;17:1140-3. (SCI) *corresponding author 62. Amyloid-beta Peptide Alteration of tau exon-10 Splicing via the GSK3-beta-SC35 Pathway. Chen KL, Yuan RY, Hu CJ *, Hsu CY *. Neurobiol Dis. 2010;40:378-85. (SCI) *corresponding author 63. Toll-like Receptor 4 and VCAM-1 in Monocyte-Endothelium Adhesion Induced by Lipopolysaccharide. Hung CH, Wu Dean, Lin FY, Yuan RY, Hu CJ*. Journal of Experimental and Clinical Medicine, 2010;2: 297-30164. 64. Get With the Guidelines-Stroke performance indicators: surveillance of stroke care in the Taiwan Stroke Registry: Get With the Guidelines-Stroke in Taiwan. Hsieh FI, Lien LM, Chen ST, Bai CH, Sun MC, Tseng HP, Chen YW, Chen CH, Jeng JS, Tsai SY, Lin HJ, Liu CH, Lo YK, Chen HJ, Chiu HC, Lai ML, Lin RT, Sun MH, Yip BS, Chiou HY, Hsu CY; Taiwan Stroke Registry Investigators. Circulation. 2010;122:1116-23. (SCI) 65. Carbamazepine-induced toxic effects and HLA-B*1502 screening in Taiwan. Chen P, Lin JJ, Lu CS, Ong CT, Hsieh PF, Yang CC, Tai CT, Wu SL, Lu CH, Hsu YC, Yu HY, Ro LS, Lu CT, Chu CC, Tsai JJ, Su YH, Lan SH, Sung SF, Lin SY, Chuang HP, Huang LC, Chen YJ, Tsai PJ, Liao HT, Lin YH, Chen CH, Chung WH, Hung SI, Wu JY, Chang CF, Chen L, Chen YT, Shen CY; Taiwan SJS Consortium. N Engl J Med. 2011;364(12):1126-33. (SCI) 66. Rapid eye movement sleep atonia in patients with cognitive impairment. Chen PC, Wu D, Chen CC, Chi NF, Kang JH*, Hu CJ*. J Neurol Sci. 2011;305:34-7 *corresponding author 67. Association between genetic variant on Chromosome 12p13 and stroke survival and recurrence: A one year prospective study in Taiwan. Hsieh YC, Seshadri S, Chung WT, Hsieh FI, Hsu YH, Lin HJ, Tseng HP, Lien LM, Bai CH, Hu CJ, Jeng JS, Tang SC, Chen CI, Yu CC, Chiou HY. J Biomed Sci. 2012;19 (1):1. (SCI) 68. Postoperative Adverse Outcomes in Surgical Patients with Dementia: A Retrospective Cohort Study. Hu CJ, Liao CC, Chang CC, Wu CH, Chen TL. World Journal of Surgery, 2012;36 (9):2051-8. (SCI) 69. Postoperative Adverse Outcomes in Surgical Patients with Epilepsy: a Population-based Study. Chang CC, Hu CJ, Chang H, Liao CC, Chen TL. Epilepsia. 2012;53 (6):987-94. (SCI) 70. OnabotulinumtoxinA improves tactile and mechanical pain perception in painful diabetic polyneuropathy. Chen WT, Yuan RY, Chiang SC, Sheu JJ, Yu JM, Tseng IJ, Yang SK, Chang HH, Hu CJ*. The Clinical Journal of Pain, 2012, (in press) (SCI) *corresponding author 71. Increase of Toll-like Receptor 4 but Decrease of Interleukin-8 mRNA Expression among Ischemic Stroke Patients under Aspirin Treatment. Wu D; Sheu JS, Liu HC; Yuan RY; Yu JM, Sheu JJ; Hung CH; Hu CJ*. Clin Biochem. 2012;45(16-17):1316-9 (SCI) *corresponding author 72. Effects of The APOE4 Allele on Functional MRI during n-back Working Memory Tasks in Healthy Middle-aged Adults. Chen CJ, Chen CC, Wu Dean, Chi NF, Chen PC, Liao YP, Chiu HW, Hu CJ*. AJNR, 2012 (in press) (SCI) *corresponding author 73. Alzheimer’s Disease and Risk of Stroke: A Population-Based Cohort Study. Chi NF, Chien LN, Ku HL, Hu CJ, Chiou HY*. Neurology, 2012 (in press) (SCI) 74. Risk of epilepsy after traumatic brain injury: a retrospective population-based cohort study. Yeh CC, Chen TL, Hu CJ, Chiu WT, Liao CC. J Neurol Neurosurg Psychiatry. 2012 Oct 31. (SCI) 75. Epistasis analysis for estrogen metabolic and signaling pathway genes on young ischemic stroke patients. Hsieh YC, Jeng JS, Lin HJ, Hu CJ, Yu CC, Lien LM, Peng GS, Chen CI, Tang SC, Chi NF, Tseng HP, Chern CM, Hsieh FI, Bai CH, Chen YR, Chiou HY; Formosa Stroke Genetic Consortium (FSGC). PLoS One. 2012;7(10):e47773. (SCI) 76. The impact Factors on the Cost and Length of Stay among Acute Ischemic Stroke. Journal of Stroke and Cerebrovascular Diseases, 2012 (in press) (SCI) 77. Functional Role of Soluble Receptor for Advanced Glycation End Products in Stroke. Tang SC, Wang YC, Li YI, Lin HC, Manzanero S, Hsieh YH, Phipps S, Hu CJ, Chiou HY, Huang YS, Yang WS, Mattson MP, Arumugam TV, Jeng JS. Arterioscler Thromb Vasc Biol. 2013 Jan 3. (in press) (SCI) 78. Multiscale Entropy Analysis of Electroencephalography during Sleep in Patients with Parkinson’s Disease. Chung CC, Kang JH, Yuan RY, Wu D, Chen CC, Chi NF, Chen PC, Hu CJ*. Clinical EEG & Neuroscience. 2013 (in press) (SCI) *corresponding author 學會服務 台灣神經學會理事 (2007-2009,2011-2013,甄審委員會委員) 台灣臨床失智症學會理事 (2006-2012,學術委員會召集人) 台灣腦中風學會副秘書長 (2007-2008)