Download DNA worksheet

Name ____________________________
Date ____________________________
DNA
1. Give the base sequence of the complementary DNA strand.
Original strand: T T A C G G T C A C C A A G C G T G
2. Draw this complete DNA molecule,using the sugars and phosphates along with the
above base pairs, in the space below.
3. Give the base sequence of the strand of mRNA read from the original DNA strand.
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4. What protein fragment would this mRNA code for ? ( write out the amino acids in
order).
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5. If the fourth nucleotide in the original DNA strand were changed from C to G, what
would
the resulting mRNA look like?
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6. What would the resulting protein look like ( amino acid sequence)?
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7. If a G were added to the original DNA strand after the 3rd nucleotide, what would the
resulting mRNA look like?
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8. What would the resulting protein look like ( amino acid sequence)?
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When DNA is bombarded with ultraviolet light, a chemical reaction occurs
between two adjoining thymine molecules. The TT complex is covalently joined
near the bottom of the molecules forming a thymine dimer (T-T). This dimer will
cause a bulge in the linear structure of the DNA sequence. If it is not repaired it
may cause serious damage to the protein that will be produced as a result of
translation. Most of these dimers are recognized and repaired by the cell before
they can cause such damage. Below you will find data collected from an
experiment trying to prove the hypothesis that age as an affect on the
development of these dimers. Graph the following data and answer the questions
that follow.
Age of Organism in
years
Number of Dimers per DNA
molecule
5
10
10
15
20
20
35
45
55
60
75
100
Graph Title:
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1. What is a dimer? ______________________________________________________.
2. Why are they important to the well being of a DNA
molecule?_____________________
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3. What does the above data indicate concerning,the general well being of, the subjects
DNA?
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4. What is the dependent variable? ___________________________________________
Answers
1. A A T G C C A G T G G T G G T T C G C A
2. Draw this complete DNA molecule,using the sugars and phosphates along with the
above base pairs, in the space below.
3. AAU CCC AGC GGU UCG CAC
4. ASPARIGINE, PROLINE, SERINE, GLYCINE, SERINE, HISTIDINE
5. AAU GCC AGC GGU UCG CAC
6. ASPARIGINE, ALANINE, SERINE, GLYCINE, SERINE, HISTIDINE
7. AAU CCC AGC GGG UUC GCA C
8. ASPARIGINE, PROLINE, SERINE, GLYCINE, PHENYALANINE, ALANINE
1. Two adjoining thymine molecules are covalently joined in a DNA molecule forming a
thymine dimer (T-T).
2. This dimer will cause a bulge in the linear structure of the DNA sequence. If it is not
repaired it may cause serious damage to the protein that will be produced as a result of
translation.
3. The older the subject gets the more dimers form. This situation may become critical if
they slip through and cause mutations in key cells.
4. Number of dimers.