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B3: 9 Polydrug Use HO1 Responding to polydrug use Framework Responding to the needs of a person who engages in polydrug use is one of many common situations encountered in general practice. It is easy to be overwhelmed by the patient who uses several drugs, and the multiple associated physical, social and psychological problems. In providing a framework for thinking about this topic, it is important to remember that the situation is even more overwhelming for the patient. Adopt a global perspective and a long term time scale in helping to achieve minimal harm – and, where accepted by the patient, a return to safer levels of use. Usually, it is of little use to try and get patients off a number of drugs simultaneously; negotiate with them about their priorities and the most significant risks to their health and well being. Generally, try approaching polydrug use sequentially, acknowledging the need to minimise harm as effectively and quickly as possible. The ability of drugs to potentiate or counteract each other should be appreciated – some people use various combinations of drugs deliberately. For example, alcohol and benzodiazepines are both CNS depressants, whereas others may combine psychostimulants and cannabis as they believe (quite inaccurately) that the effects of one will “oppose” or negate the other. At other times, patients may use one drug to treat the effects of withdrawal of another drug, hence making the withdrawal from any one drug more complex. Some patients may “transfer” their dependence from one drug to another during the treatment process. Faced with the reality of giving up one drug, their attention may focus on another. Giving up amphetamines, for example, may lead to increased benzodiazepine use, at least in the short term. As the clinician, we need to acknowledge – and share with the patient – the likelihood of these fluctuations and be prepared to ride them out. We need to be cognisant of the range of problems that can be associated with any one drug in order to be “on top” of the situation with patients changing between several drugs. Take the long view – and reassure the patient they will get the long term support necessary to achieve overall goals. Standards 8.1 8.2 8.3 The general practitioner should know the potential range of harms associated with each type of drug use. The general practitioner should know how the main classes of drugs tend to interact with each other. The general practitioner should be able to prioritise their approach to polydrug use to recognise the most hazardous (in terms of immediate harm to the patient) drug use first. Resource Kit for GP Trainers on Illicit Drug Issues Part B3 Clinical Complexity: Polydrug use Practical guidelines Prioritising your approach means trying to minimise the risk and harm to the patient, for example, try addressing injecting drug use complications before addressing other issues. While you need to personalise your approach, generally deal with the problems that result in most harm first. It may be that behaviours or risks associated with the use of a particular drug may require your immediate attention rather than focussing on the drug itself. Other than this, the approach given to different types of drugs should progress as outlined in the preceding chapter. We are trying to assess the relative risk of each element of the patient’s alcohol and drug use. Remember that they may be at different “stages of change” for each drug – they may be actively trying to change their use of amphetamines, contemplating reducing their drinking, but not even acknowledging that their tobacco use is a health risk simultaneously. Work your way from one to another, and take a long term outlook. Relapse issues may be magnified with polydrug situations – keep pointing out to your patient the small gains they continue to make and emphasise the importance of continuing to attend regularly for support, monitoring and follow up. Polydrug use is often a situation where early referral for a specialist opinion can help to guide a community based care plan enacted by the general practitioner. “Shared care” models of treatment between general practice and drug and alcohol agencies are now being tried with increasing success in a variety of settings – know where to get help and know how to use it. Source: Wales, S., Brough, R. & Dammery, D., 1995?, Drink, Drugs and Doctors: A guide to quality care. Standards and Guidelines for General Practice (Draft), Draft Standards and Guidelines Working Party, The Royal Australian College of General Practitioners, Carlton, Victoria. Resource Kit for GP Trainers on Illicit Drug Issues Part B3: Clinical Complexity: Polydrug use