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Endocrine System Histology and Models ENDOCRINE SYSTEM Dry Lab Questions • Function: maintain homeostasis • • • • • Thymus gland (site of maturation of white blood cells) Thyroid gland (secretes thyroid hormone and calcitonin) Parathyroid gland (secretes parathyroid hormone) Adrenal gland (secretes aldosterone) Pituitary gland (secretes FSH, etc. The neurohypophysis stores and releases hormones produced in the hypothalamus) • Ovary (also an endocrine gland; secretes estrogen) • Testes (secretes testosterone) • Pancreas (secretes insulin; lack= diabetes mellitus) ENDOCRINE MODELS • • • • • • • Thyroid gland Adrenal gland Thymus gland Pituitary gland Pineal gland Ovary/Testes Pancreas Adrenal and Thyroid glands Thyroid Gland Parathyroid Glands (small pink dots) Thymus Gland Endocrine Glands Adrenal gland Pancreas Testes Skip Pituitary gland Pineal gland Adrenal gland Skip Ovary Testes Pancreas Spleen Duodenum Pancreas Gall bladder Spleen Kidney Pancreas Adrenal gland Kidney ENDOCRINE HISTOLOGY • • • • Ovary Testes Pancreas Thyroid gland Ovary Skip Testes Seminiferous tubules Testes Pancreas Acinar cells (secrete enzymes) Islet of Langerhans (secretes insulin) Thyroid Gland Secretes calcitonin and thyroid hormone Thyroid Gland Renal System Histology and Models Renal system in cat: – Kidney – Ureter – Urinary bladder Kidney Ureter Kidney Ureter Urinary bladder Ureters Urinary Bladder Rugae inside urinary bladder that was cut open Spleen Adrenal gland Kidney Renal artery Ureter Urinary bladder Adrenal gland Kidney Ureter Urinary bladder Prostate gland Urethra vasa recta peritubular capillaries vasa recta peritubular capillaries Kidney Regions • The kidney is divided into three REGIONS. • If the question asks you to name the REGION, the answer is one of the below: – CORTEX – MEDULLA – RENAL PELVIS REGIONS Cortex Medulla Renal Pelvis Kidney Structures • If the question asks you to name the STRUCTURE, it is one of the below: • Within the cortex, you will find the glomeruli and the proximal and distal convoluted tubules. • Within the medulla you will find the loops of Henle, collecting tubules, the pyramids and the columns (pale area between the pyramids). • Within the renal pelvis you will find the hilus, which branches into the major calyxes, which branch into the minor calyxes. On this model you need to know the regions, vessels, and the following structures: Pyramids Hilus Ureter Major calyx Minor calyx Hilus Major calyx Minor calyx Ureter Renal artery Segmental artery Interlobar artery Interlobular artery Arcuate artery Interlobar artery Interlobular artery Arcuate artery REGIONS Cortex Medulla Renal pelvis STRUCTURES Pyramids Major calyx Minor calyx Hilus Ureter VESSELS Interlobular artery Arcuate artery Interlobar artery Segmental artery Renal artery KIDNEY MODEL • Glomerulus • Proximal convoluted tubule • Descending loop of the nephron – Thick segment – Thin segment • Ascending loop of the nephron – Thick segment – Thin segment • Distal convoluted tubule • Collecting tubule (where urine is most similar to the bladder) • Vasa recta Glomerulus Vasa recta Distal convoluted tubule Proximal convoluted tubule Glomerulus Descending loop of the Nephron Ascending loop of the nephron Collecting tubule (where the fluid is most similar to urine found in the bladder) Study Tip: To get oriented, always start at the glomerulus and run your finger down the proximal convoluted tubule. When it loops back up and thickens, you are now at the distal convoluted tubule. Thick segment of the ascending loop of the nephron Thick segment of the descending loop of the nephron Thin segment of the ascending loop of the nephron Thin segment of the descending loop of the nephron GLOMERULUS Efferent arteriole Afferent arteriole Glomerular capsule The glomerular space is where urine is most dissimilar to the urine in the bladder KIDNEY SLIDES • Glomerulus • Kidney tubules (simple cuboidal epithelium) Glomerulus Tubule Skip Tubule Glomerulus Kidney Glomerulus Tubule Pancreas: don’t get this confused with a glomerulus in the kidney! Pancreas Kidney