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TIMETABLE OF LECTURING IN HUMAN MEDICINE 1st of March (Prof. Natale) The general basis of human anatomy The anatomical and physiological correlated in the enteric nervous system The gut-brain axis as a gateway to environmental, infectious and diet-related agents of disease with an emphasis on novel environmental casuses of neurodegeneration 7th of March (Prof Ruffoli) The movement control with general elements of locomotion The human cerebellum and neural control The environmental causes of cerebellum-related movement disorders 14th of March (Prof. Fornai) The anatomy and physiology of motivation and reward in humans The reward centers in the human brain Environment-induced alteration in the reward system with an emphasis on drug of abuse psychostimulants, neurotoxins and drug-induced human behavioral alterations THE HUMAN MEDICINE WITHIN THE PH MODULE Introductory statement This part of the module represent a mini-course aimed to explain the anatomy, the functional correlates and general disease-mechanisms of most systems specific of the human body. The mini-course will emphasize the interrelationships among locomotor, cardiorespiratory, urinary (o urogenital), endocrine and nervous systems. A survey on the involvement of these organ systems in maintaining homeostasis and their vulnerability following exposition of prototype environmental factors (toxic pollutants, detrimental factors in animal and vegetal diet ) is included. Syllabus and learning objectives The student must learn the human anatomo-physiological uniqueness which characterize the conditions of health and disease. Each topic will be integrated giving the main principles (selected according to their relevance as established by: Relevance to disease, relevance to produce homeostasis, educational relevance meant as prototypical explanation to understand the main principles which apply to most component of the human body) Teaching modalities The course is mainly grounded based on lectures in presence but it will greatly profit from constant interactions and assessment of understanding of each topic. In addition Dynamic power points, movies showing actual or simulated reality of human organs in health and disease will be offered under constant tutoring. During lectures, an active participation of each participant will be encouraged aiming to brainstorm the most challenging issues for public health. Learning modalities The student learns by attending lectures and the other activities mentioned at previous point, by participating in choral discussions, by answering or questioning specific issues, by inter student tutoring in the extra time where individual as well as group study will also carried out based on learning material provided in advance on a web platform/website or via e-mail. This latter material will follow up preliminary introducing study provided before the beginning of the mini-course during the month before the-mobility stage. Assessment Achievement The learning level will be assessed by frequent in itinere discussion and test and final multiple choice test and/or oral exam (when necessary). At this stage each student is required to possess adequate knowledge of the each topic course in a way which is sufficient to establish the learning outcome associated to such a mini-course of basic medicine as follows. Learning outcomes (and their application to subject specific competencies in Public health) At the end of the mini-course of basic medicine belonging to the module in PH, the student is expected to possess a general knowledge of main human organ and systems and how they are engaged in healthy human life. The student is required to know the general principles which correlate in a holistic perspective different organs of the human body to achieve an optimal physiological control. The student is required to be quite familiar with the most frequent causes of disease due to abnormal environmental exposure. This latter outcome is intended in a logical framework where the nature of the toxic agent is understood on the basis of its detrimental interaction with the physiology of the human systems. At this learning stage potential outcome to be explored may extend to clues on remedies based on the logical reversal of the pathophysiological chain of event.