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Roach's Introductory Clinical Pharmacology, Tenth Edition (Susan M. Ford and Sally S. Roach ) Lesson Plans Chapter 8—Antibacterial Drugs That Interfere With Protein Synthesis Goals of the Lesson: Cognitive: Students will be able to explain the four groups of broad-spectrum antibiotics. They will be able to discuss the nursing diagnoses, preadministration and ongoing assessment activities, how to manage adverse reactions, and educating patients and their families about the reactions. Learning Objectives: The lesson plan for each objective starts on the next page. 8.1 Discuss the uses, general drug actions, adverse reactions, contraindications, precautions, and interactions of antibacterial drugs that interfere with protein synthesis. ...................................................................................................... 2 8.2 Discuss important preadministration and ongoing assessment activities the nurse should perform on the patient taking an antibacterial drug that interferes with protein synthesis.. ................................................................................................ 6 8.3 List nursing diagnoses particular to a patient taking an antibacterial drug that interferes with protein syntehsis.......... 8 8.4 Discuss ways to promote an optimal response to the therapy, how to manage adverse reactions, and important points to keep in mind when educating patients about the use of antibacterial drugs that interfere with protein synthesis.. ........10 Legend: IR: Instructor’s Resource; SR: Student’s Resource; PPT: PowerPoint (IR); TG: Test Generator (IR) Page 1 of 11 Copyright © 2014 Wolters Kluwer | Lippincott Williams & Wilkins Roach's Introductory Clinical Pharmacology, Tenth Edition (Susan M. Ford and Sally S. Roach ) Chapter 8 Antibacterial Drugs that Interfere with Protein Synethesis Objective 8.1 Discuss the uses, general drug actions, adverse reactions, contraindications, precautions, and interactions of antibacterial drugs that interfere with protein synthesis. Lecture Outline Content Introduce the chapter by explaining of antibacterial drugs that interfere with protein synthesis. In addition, also explain their use, the general drug action, adverse reactions, and the precautions. Text page 84-88 PPT slide 2–21 Figures, Tables, and Features Resources and In-Class Activities Outside Assignments/Evaluation Table Pre-Lecture Quiz Written Assignment Summary Drug Table: Antibacterial Drugs That Interfere With Protein Synthesis pp. 92-93 True/False Figure Figure 8.1 p. 84 Page 2 of 11 Copyright © 2014 Wolters Kluwer | Lippincott Williams & Wilkins Prepare a report on the following antibiotics used for the treatment of Tetracyclines should infections: tetracyclines, be given only after aminoglycosides, having a proper meal. The macrolides inhibit macrolides, and lincosamides. protein synthesis in Draw a comparison susceptible bacteria, chart stating their causing cell death. details. In a patient taking an List their adverse aminoglycoside, if reactions and constipation occurs, the contraindications. nurse should save a sample of the stool and Web Assignment test it for occult blood Conduct online research on using a test such as antibacterial drugs that Hemoccult. interfere with protein synthesis and prepare a Fill-in-the-Blank report on the following: Manufacturing __________ are companies contraindicated in infants younger than 1 Kit name Primary matrices month old. Uncomplicated urethral, endocervical, Test Bank TG Questions 1–3, 5, 7–8, or rectal infections 17–18, 21–23, 25, and 27 caused by Chlamydia trachomatis can be Instructor’s Notes Roach's Introductory Clinical Pharmacology, Tenth Edition (Susan M. Ford and Sally S. Roach ) Chapter 8 Antibacterial Drugs that Interfere with Protein Synethesis cured using __________. __________ is a disease that affects the myoneural junction in nerves and is manifested by extreme weakness and exhaustion of the muscles. A macrolide when administered with _________ causes increased serum levels. Discussion Topics A patient admitted to the hospital with an upper respiratory infection was treated with macrolides. The patient was also given digoxin. What are the adverse reactions that the nurse should check for? What could be the effect of interaction of digoxin with a macrolide? A patient is admitted to a hospital with a skin and soft tissue infection. Which antibiotic can be used to treat the skin and soft tissue infection? What are the adverse effects of the antibiotic? Page 3 of 11 Copyright © 2014 Wolters Kluwer | Lippincott Williams & Wilkins Spanish-English Audio Glossary Roach's Introductory Clinical Pharmacology, Tenth Edition (Susan M. Ford and Sally S. Roach ) Chapter 8 Antibacterial Drugs that Interfere with Protein Synethesis Case Study Maria Lopez is a 24-yearold Hispanic woman. She presents to the physician’s office today seeking treatment for her acne. Her only medication is Ortho Tri-Cyclen Lo. The physician writes Ms. Lopez a prescription for doxycycline (Doryx) 150 mg once daily. What should the nurse tell Ms. Lopez about taking oral contraception with Doryx? What adverse reactions should the nurse discuss with Ms. Lopez? Preparing for NCLEX-PN Know Your Drugs Clients sometimes know a medication by the brand (or trade) name and not the generic name. To help you recognize both names, match the brand name with the generic name of the same medication. Prepare for the NCLEX-PN Build Your Knowledge Question 1 Apply Your Knowledge Question 8 Page 4 of 11 Copyright © 2014 Wolters Kluwer | Lippincott Williams & Wilkins Roach's Introductory Clinical Pharmacology, Tenth Edition (Susan M. Ford and Sally S. Roach ) Chapter 8 Antibacterial Drugs that Interfere with Protein Synethesis Alternate-Format Questions Question 9 Strategies for Effective Training Legend: IR: Instructor’s Resource; SR: Student’s Resource; PPT: PowerPoint (IR); TG: Test Generator (IR) Page 5 of 11 Copyright © 2014 Wolters Kluwer | Lippincott Williams & Wilkins Roach's Introductory Clinical Pharmacology, Tenth Edition (Susan M. Ford and Sally S. Roach ) Chapter 8 Antibacterial Drugs that Interfere with Protein Synethesis Objective 8.2 Discuss important preadministration and ongoing assessment activities the nurse should perform on the patient taking an antibacterial drug that interferes with protein synthesis. Lecture Outline Content Text page State the steps the nurse should 88-89 take before administering antibacterial drugs that interfere with protein synthesis. In addition, state the signs and symptoms of an infection. Explain the factors a nurse should consider before administering these antibiotics to the patient. Discuss the vital changes that can be observed during ongoing assessment of a patient receiving these antibiotics. Discuss the expected outcomes of a patient’s treatment with these antibiotics. PPT slide Figures, Tables, and Features 22, 23, and 26 Resources and In-Class Activities Outside Assignments/Evaluation Pre-Lecture Quiz Clinical Assignment True/False Visit a health care center and observe a nurse administering antibacterial drugs that interfere with protein synthesis to patients. Prepare a report on the following: Steps taken by the nurse before administering an antibiotic Information obtained from the patient before administering a drug and its importance Information given to the patient and family about the prescribed antibiotic course Food impairs the absorption of lincomycin. Discussion Topics A patient admitted to the hospital with an upper respiratory infection was treated with macrolides. The patient was also given digoxin. What are the adverse reactions that the nurse should check for? What could be the effect of interaction of digoxin with a macrolide? Test Bank A patient preparing for abdominal surgery is administered aminoglycosides. What should the nurse monitor for while caring for the patient during treatment? Page 6 of 11 Copyright © 2014 Wolters Kluwer | Lippincott Williams & Wilkins TG Questions 10–12 Spanish-English Audio Glossary Instructor’s Notes Roach's Introductory Clinical Pharmacology, Tenth Edition (Susan M. Ford and Sally S. Roach ) Chapter 8 Antibacterial Drugs that Interfere with Protein Synethesis Preparing for NCLEX-PN Calculate Medication Dosages Questions 1, 2 Prepare for the NCLEX-PN Build Your Knowledge Questions 2 Apply Your Knowledge Questions 6, 7 Alternate-Format Questions Question 10 Strategies for Effective Training Legend: IR: Instructor’s Resource; SR: Student’s Resource; PPT: PowerPoint (IR); TG: Test Generator (IR) Page 7 of 11 Copyright © 2014 Wolters Kluwer | Lippincott Williams & Wilkins Roach's Introductory Clinical Pharmacology, Tenth Edition (Susan M. Ford and Sally S. Roach ) Chapter 8 Antibacterial Drugs that Interfere with Protein Synethesis Objective 8.3 List nursing diagnoses particular to a patient taking an antibacterial drug that interferes with protein synthesis. Lecture Outline Content Text page Explain the nursing diagnoses for 89 a patient receiving an antibacterial drug that interferes with protein synthesis. PPT slide Figures, Tables, and Features 24 and 25 Resources and In-Class Activities Outside Assignments/Evaluation Pre-Lecture Quiz Group Assignments True/False Have a short discussion on the nursing diagnoses associated with The minocycline administering of (Minocin) and antibacterial drugs that oxytetracycline (Terramycin) drugs can interfere with protein synthesis. be taken with food Fill-in-the-Blank __________ is a drug related to lincomycin that can cause the patient's eyes to have difficulty focusing and accommodating to light. Case Study Maria Lopez is a 24-yearold Hispanic woman. She presents to the physician’s office today seeking treatment for her acne. Her only medication is Ortho Tri-Cyclen Lo. The physician writes Ms. Lopez a prescription for doxycycline (Doryx) 150 Page 8 of 11 Copyright © 2014 Wolters Kluwer | Lippincott Williams & Wilkins Test Bank TG Questions 4, 6, 13, 16, 24, and 28–30 Spanish-English Audio Glossary Instructor’s Notes Roach's Introductory Clinical Pharmacology, Tenth Edition (Susan M. Ford and Sally S. Roach ) Chapter 8 Antibacterial Drugs that Interfere with Protein Synethesis mg once daily. How should the nurse tell Ms. Lopez to take the Doryx? Preparing for NCLEX-PN Strategies for Effective Training Legend: IR: Instructor’s Resource; SR: Student’s Resource; PPT: PowerPoint (IR); TG: Test Generator (IR) Page 9 of 11 Copyright © 2014 Wolters Kluwer | Lippincott Williams & Wilkins Roach's Introductory Clinical Pharmacology, Tenth Edition (Susan M. Ford and Sally S. Roach ) Chapter 8 Antibacterial Drugs that Interfere with Protein Synethesis Objective 8.4 Discuss ways to promote an optimal response to therapy, how to manage adverse reactions, and important points to keep in mind when educating patients about the use of antibacterial drugs that interfere with protein synthesis. Lecture Outline Content Explain how a nurse can help to avoid adverse reactions from these antibiotics during oral administration in a patient. In addition, state the tetracyclines that may be taken with food and the precautions to be taken during oral administration of antibacterial drugs that interfere with protein synthesis State the ideal time for oral administration of antibacterial drugs that interfere with protein synthesis Discuss monitoring and managing patient needs during parental administration of antibacterial drugs that interfere with protein synthesis. State the category of patients who are at risk of injury after administration of antibacterial drugs that interfere with protein synthesis Explain the importance of educating the patient and family about the prescribed therapeutic Text page PPT slide 89-91 27–39 Figures, Tables, and Features Resources and In-Class Activities Outside Assignments/Evaluation Patient Teaching for Improved Patient Outcomes p. 91 Pre-Lecture Quizzes Clinical Assignment True/False Visit a health care center and observe a nurse administering antibacterial drugs that interefere with protein synthesis to patients. Prepare a report on the following: Steps taken by the nurse before administering an antibiotic Information obtained from the patient before administering a drug and its importance Information given to the patient and family about the prescribed antibiotic course Page 10 of 11 Copyright © 2014 Wolters Kluwer | Lippincott Williams & Wilkins Food impairs the absorption of lincomycin. Preparing for NCLEX-PN Prepare for the NCLEX-PN Build Your Knowledge Questions 3, 4, 5 Strategies for Effective Training Test Bank TG Questions 14, 15, 20, and 26 Journal Articles Heart Matters: Hearts Afire: Infective Endocarditis Instructor’s Notes Roach's Introductory Clinical Pharmacology, Tenth Edition (Susan M. Ford and Sally S. Roach ) Chapter 8 Antibacterial Drugs that Interfere with Protein Synethesis regimen of antibacterial drugs that interfere with protein synthesis. Kim McCarron MS, CRNP Free Nursing Made Incredibly Easy! May/June 2012 Volume 10 Issue 3 Pages 44–48 Spanish-English Audio Glossary Legend: IR: Instructor’s Resource; SR: Student’s Resource; PPT: PowerPoint (IR); TG: Test Generator (IR) Page 11 of 11 Copyright © 2014 Wolters Kluwer | Lippincott Williams & Wilkins