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How your body defends itself from foreign invasion. NON-SPECIFIC NOT differentiate between invaders Same response for pollen HIV 1 & 2nd lines of defense SPECIFIC Creates specific response for each invader Ability to remember & target invaders (antibodies) 3rd line of defense MAJOR CHEMICALS/PROTEINS: Antigen Protein matches to an antigen used to “remember” You have a different antibody for every different foreign molecule ever entered your body Histamine Unique protein (name tag) all living tissue Antibody Interferon Chemical triggers allergy response (runny nose, water eyes, blood flow) Protein release by infected cells “interferes” w/ viral reproduction Interleukin Chemical messenger controls temperature regulation SAME RESPONSE TO ALL INVADERS 1st Line of Defense Physical Barriers 2nd Line of Defense Attempts to prevent invasion Skin Mucous membranes pH Digestive enzymes Inflammatory Resp. Triggered by tissue damage Increase blood flow to promote clotting WBC’s consume all foreign material Fever 3RD LINE 0F DEFENSE DIFFERENT RESPONSE FOR EACH INVADER Humoral Response B-cells “highlights” foreign material Produces Antibodies – “memory cells” Cell-Mediated Response T-cells “killer” cells Consume invaders highlighted by the bcells PASSIVE Requires no effort Antibodies given out Examples: Mother fetus (umbilical chord) Mother baby (breast milk) ACTIVE Requires effort Body must produce antibodies by fighting off infection Natural – get chicken pox Artificial – chicken pox vaccine T-cells (kill invaders) antibodies (remember invaders) wbc’s (consume invaders) pathogen reproductive rates An exagerated immune response to typically harmless environmental antigens Only activate 1st & 2nd lines of defense Never reach 3rd – never form antibodies that would prevent re-occurance Why Overmedicated, over vaccinated & under exposed Immune system learns it job by practicing, if you give it nothing to practice on, it will find something (grass, pollen, food allergies, etc.) Read the article & be prepared to respond to the following essay prompts: VACCINATION, ISOLATION or EXPOSURE? Which method(s) would you choose for your own children? Describe several ways to improve or boost you and/or your future children’s immune system? Name method & describe how it helps.