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Download - Mediterranean Journal of Hematology and Infectious
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Mehdi Taghipour M.D Shiraz University of Medical Sciences Medical School, Zand St, Shiraz, Iran [email protected] Dr. Giuseppe Leone Editor-in-Chief The Mediterranean Journal of Hematology and Infectious Diseases (MJHID) November 23, 2014 Dear Dr. Wajcman, I am pleased to submit an original research article entitled “Reliability of different RBC indices and formulas in discriminating between β-thalassemia minor and other causes of microcytic hypochromic anemia” by Elahe Bordbar, Mehdi Taghipour and Beth E. Zucconi for consideration for publication in the Journal of The Mediterranean Journal of Hematology and Infectious Diseases. In this manuscript, we applied RBC indexes of hypochromic microcytic anemic individuals to five previous published formulas and our new formula to detect the best one for premarital beta thalassemia minor screening. We showed that none of the formulas had 100% sensitivity or specificity in finding beta thalassemia minor individuals; however our new formula and ShineLal formula are the best for this goal. We believe that this manuscript is appropriate for publication by the Journal of The Mediterranean Journal of Hematology and Infectious Diseases because it had something new to create new, effective formula in screening of cases with minor thalassemia. Our manuscript creates a paradigm for future studies in evaluation of different formulas in different populations. This manuscript has not been published and is not under consideration for publication elsewhere. We have no conflicts of interest to disclose. Thank you for your consideration! Sincerely, Mehdi Taghipour, MD Shiraz University of Medical Sciences
