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(R. rickettsii) By, Muneeb Jaffry Kingdom Species Bacteria Proteobacteria Alphaproteobacteria Rickettsiales Rickettsiaceae Rickettsia R. rickettsii Shape: Coccobacilli (rodlike) Gram Stain: Gram-negative(do not stain well) Respiration: aerobic Three Layers ◦ An Innermost cytoplasmic membrane ◦ Outer layer (resembles most membranes, fluidity) ◦ Cell wall If ATP is used, oxygen metabolized and consumed “The basis for the obligate parasitism of these cells is that they require the rich cytoplasm to stabilize an unusually permeable cell membrane.” Replication ◦ Normally go through Binary Fission ◦ If nutritional conditions are poor, growth ceases and rickettsia begins to grow long filamentous forms S. Burt Wolbach ◦ Recognized it as an intracellular bacterium in 1919 ◦ Proposed the name Dermacentroxenus rickettsii Emile Brumpt ◦ Felt that rickettsii belonged to the genus Rickettsia Rocky Mountain Spotted Fever ◦ Caused by Rickettsia rickettsii spread by Dermacentor ticks ◦ Initial signs and symptoms of the disease include sudden onset of fever, headache, and muscle pain, followed by development of rash ◦ Treated by antiobiotics ◦ Require vectors for transmission Transovarial transmission (Femaile tick passes on R. rickettsii to eggs) http://eyepathologist.com/disease.asp?IDNUM=310710 http://en.wikipedia.org/wiki/Rickettsia_rickettsii http://bioweb.uwlax.edu/bio203/s2008/gibson_chel/Classification.htm http://www.cartage.org.lb/en/themes/sciences/lifescience/generalbiology/microbiology/Ricke ttsia/Rickettsia.htm http://www1.cleveland.edu/Mott/BIOL%20301%20Lec8.ppt http://bioweb.uwlax.edu/bio203/s2008/gibson_chel/Rocky%20Mountain%20Spotted%20Fever. htm http://www.pasteur.fr/infosci/archives/e_bpt0.html http://www.e-healthcaresolutions.com/AAFP/lantus-afp-0111inter.php?url=http://www.aafp.org/afp/2005/0615/p2323.html http://www.azdhs.gov/phs/oids/vector/rmsf/rocky_mountain.htm http://diverge.hunter.cuny.edu/~weigang/Lecture-syllabus.html
