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Isaac Levinsky Page 1 Irritable Bowel Disease (IBD) and Irritable Bowel Syndrome (IBS) Irritable Bowel Disease (IBD) definition: Inflammatory bowel disease (IBD) refers is a chronic conditions that cause inflammation in some part of the intestines. Inflammation leads to ulcers, serious digestive problems, strictures (narrowing), possible blockages and the need for surgery and or medication. There are two types of IBD, including Crohn’s disease and Ulcerative Colitis: Crohn's disease is a form of IBD and it can occur anywhere along the digestive tract – from the mouth to the anus. It affects the deeper layers of the digestive lining and diseased areas can be present anywhere in the digestive system. Strictures, narrowing of the intestine can lead to blockages, pain, and the need the surgery in Crohn’s. Unlike Crohn's disease, Ulcerative colitis only involves the colon and rectum. Inflammation and ulcers typically affect only the innermost lining in these areas, compared with the deeper lesions seen in Crohn's disease. Irritable Bowel Syndrome (IBS) definition: Irritable bowel syndrome is not a disease; it is a syndrome or group of symptoms. IBS affects the colon (large intestine). IBS is a functional disorder, which means that the functioning of the bowel is incorrect, yet the tissue remains undamaged. IBD and IBS are not the same condition: Unlike IBD (Crohn’s and Ulcerative colitis), IBS does not involve inflammation, and it does not damage the digestive system or cause ulcers. IBD often leads to serious complications such as surgery or even intestinal blockage. 66% to 75% of persons with Crohn’s disease will require one or more surgeries to remove diseased tissue, and remove strictures or blockages in the small or large intestine most often. 20% of persons with Ulcerative colitis will require surgery on the large intestine. IBS does not require surgery because it is not structural. Symptoms of Irritable Bowel Disease: Symptoms are similar for Crohn’s and Ulcerative colitis, but vary depending on severity and where there is actively diseased tissue. Abdominal pain or cramping Diarrhea multiple times per day Bloody stools Weight loss IBD can cause problems outside of the digestive system: • Mouth sores and skin problems • Arthritis • Eye problems that affect vision Symptoms of Irritable Bowel Syndrome: The main symptoms of IBS are • abdominal pain or discomfort, usually relieved or related to bowel movements • chronic diarrhea, constipation, or a combination of both 1 Isaac Levinsky Page 2 Medication Issues: IBD Treatment has two goals including achieving remission and maintaining remission. Medications are targeted to reduce inflammation of the intestine as inflammation causes symptoms. Types: IBD: Aminosalicylates, Corticosteroids, Immunomodulators, Antibiotics, Biologic therapies. Aminosalicylates: mesalamine, balsalazide, balsalazide Corticosteroids: prednisone, methylprednisolone, hydrocortisone, Budesonide (specific to Crohn’s) Immunomodulators: Azathioprine, 6-mercaptopurine (6-MP), Cyclosporine A, tacrolimus, Methotrexate Antibiotics: Metronidazole, Ciprofloxacin Biologic Therapies: Anti-TNF: Infliximab, Adalimumab, Certolizumab pegol, Integrin Receptor Antagonist: Natalizumab IBS: Medications for diarrhea, for constipation, for pain and cramping, and for anxiety or depression Diarrhea: diphenoxylate and loperamide, Bile acid binding agents (cholestyramine), Alosetron Constipation: Lubiprostone, Osmotic laxatives, Polyethylene glycol, Stimulant laxatives Pain and Cramping: Anticholinergics (antispasmodics), antidepressants Anxiety or Depression: antidepressants, anti-anxiety (including benzodiazepines) Adherence: Medications have side effects and may have to be taken for long periods of time. Some medications have serious, potentially fatal side effects. Adherence is problematic due to side effects, high cost, and chronic need for symptom relief. Effect of noncompliance: Noncompliance can be serious for IBD and can lead to serious complications. Long term consequences of noncompliance in IBD can be disability, pain, functional impairment, increased need for surgery and hospitalizations or death. Noncompliance for IBS is less serious but leads to the symptoms of IBS going untreated. Other Management Issues: Diet and stress play a role in IBS and persons with IBS should learn to avoid their trigger foods. IBD (Crohn’s and Ulcerative colitis) are not caused or exacerbated by a person’s diet. If inflammation is severe and causes strictures or narrowing, caution should be taken with foods that could become lodged behind the stricture. Health Behavior Change Areas Assess relevance Assess patient’s perception of importance of change in area Assess prior efforts to change Emotional Regulation Assess relevance, skill level, need for training Tracking Form - explain 2 Isaac Levinsky Page 3 Intervention/Technique Handout Eliminating or Reducing Environmental Stressors: Plan ahead: Bring medication to manage symptoms, be careful with your diet, find out where the bathrooms are located, bring emergency supplies when you travel (toilet paper, medication). Reducing Vulnerabilities & Risk Factors: Diet and nutrition: Avoid foods that cause an increase in symptoms. Speak to your Doctor about specific dietary plans or nutritional needs. Also, do not take NSAIDs if you have IBD as they irritate the digestive system. Alcohol moderation: Alcohol increases the motility of the digestive tract. Limit alcohol to improve IBS and IBD symptoms. Increase activity levels and exercise: Low impact aerobic exercise can improve mood and aid digestion. Increasing Coping Skills: Problem-Solving: If you do not feel well, listen to your body. Generating options Goal setting / means-end thinking Reducing/eliminating cognitive errors: Pay attention to automatic negative thoughts Assertiveness training: Communicate your needs and learn to set boundaries Increasing pleasurable activities: Participate in activities you enjoy. Increasing social interaction: Do not isolate, participate socially. Acceptance and commitment techniques: Dealing with a chronic illness is tough, be easy on yourself. Values clarification: Remember that before you can take care of others, you must take care of yourself first. Reducing Perceived Stress: Alternate response to stress - relaxation / mindfulness: Stress is the enemy, learn to relax. Stress management techniques: Deep breathing, yoga, tai chi, progressive muscle relaxation Anger management techniques: Count to ten. Take a deep breath. Getting angry will only add to your stress level. Communication training: Communicate your needs and make others aware of what your condition involves and when you are not feeling well. Cognitive reappraisal of perceived stress level: A positive attitude and remembering a situation is not “the end of the world” 3 Isaac Levinsky Page 4 Keeping Track IBS and IBD MONDAY TUESDAY WEDNESDAY THURSDAY FRIDAY Your Symptoms Rate on a scale of 0 = no symptoms whatsoever; 10= unbearable symptoms Stressful Events Rate how stressful the day was for you, with 0 = not stressful, and 10 = extremely stressful Deep. Breathing Whether or not you practiced Yes or No Medication Whether or not you took your medication - Yes or No 4