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The Importance of Mitosis The need to heal! The need to grow! How do cells have the information to reproduce? DNA Made of nucleotides Phosphate sugar Nitrogen base Adenine Guanine Cytosine thymine DNA in detail Uncoiled DNA called chromatin looks like spaghetti - between cell divisions Coiled DNA in the form of an (x) shape is called a chromosome – occurs during cell division Chromosomes Chromosomeconsists of two identical halves connected together by a centromere Chromatid- a half of one chromosome. The chromosomes of a homologous pair Carry genes for the same characteristics at the same place, or locus Chromosomes Centromere Sister chromatids How many chromosomes do we have?? Each human diploid cell is 2N and contains 46 total 23 identical pairs ( 23 x 2 = 46 ) “homologous chromosomes” carry the same traits Cell Cycle G1 = cell grows S = DNA replication G2= Prepare to divide M= Mitosis INTERPHASE How we make more identical cells. mitosis Stages of Mitosis Interphase Prophase Metaphase Anaphase Telophase (IPMAT) Stages of mitosis id: slide #1 Interphase DNA, uncoiled Stages of mitosis id: slide #2 Prophase DNA, Coils and nuclear membrane disappears. Stages of mitosis id: slide #3 Metaphase DNA lines up in the MIDDLE DNA is coiled in chromosomes Stages of mitosis id: slide #4 Anaphase DNA Separates It is pulled APART to opposite sides of the cell Stages of mitosis id: slide #5 Telophase DNA separated and new membrane is forming Cytokinesis 2 Identical cells formed (clones) Plant Interphase Cell prepares for division by: •replicating DNA and organelles •increasing cell size Plant Interphase Plant Prophase Cell prepares for nuclear division by: •condensing DNA into movable packages called chromosomes Plant Prophase Plant Metaphase Plant Metaphase Cell prepares chromosomes for division by: •aligning chromosomes at cell equator •attaching spindle fibers from each new daughter cell pole to each chromosome at the centromere Plant Anaphase Chromosomes divide: •spindle fibers pull chromosomes apart •one-half of each chromosome (chromatid) moves to a new daughter cell Plant Anaphase Plant Telophase Cytoplasm divides: •DNA decondenses and two nuclei form •new cell wall (cell plate) appears between the two nuclei to form two new daughter cells Plant Telophase Plant Interphase Cell prepares for division by: •replicating DNA and organelles •increasing cell size Plant Interphase Plant Mitosis Interphase Prophase Metaphase Anaphase Telophase Interphase Normal cell cycle (Mitosis) Happens everywhere in your body when you need a new cell. Red blood cells are reproduced fast Heart brain and muscle cells are reproduced more slowly Abnormal cell cycle Cancer= cell cycle is to fast Chemo stops or slows down the cell cycle